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MON-P263: Increased Awareness of Obesity is Related with Decreased Metabolic Syndrome Risk in Obese Children
Obesity and the metabolic syndrome 2 overweight/obese individuals. A larger sample size may be required to detect changes in such variable anthropometric measures. Reference 1. EFSA Journal 2009;7(9):1254. Disclosure of Interest: S. Zaremba Other: Nairn’s Oatcakes Ltd., Edinburgh, manufactured β-glucan-enriched oatcakes and has given financial support towards analytical costs for SZ’s PhD study., I. Gow: None declared, J. McCluskey: None declared, G. McDougall: None declared, S. Drummond: None declared.
MON-P262 ACUTE EFFECTS OF DIFFERENTLY COMPOSED MEALS ON POSTPRANDIAL METABOLISM IN OLDER ADULTS WITH A CVD RISK PHENOTYPE Y. B. Schönknecht1 *, S. Crommen1, B. Stoffel-Wagner2, M. Coenen3, R. Fimmers4, P. Stehle1, S. Egert1. 1Department of Nutrition and Food Sciences, University of Bonn, 2Institute of Clinical Chemistry and Clinical Pharmacology, 3Study Centre, Institute of Clinical Chemistry and Clinical Pharmacology, 4 Institute of Medical Biometry, University Hospital Bonn, Bonn, Germany Rationale: The postprandial situation is characterized by lipaemia, glycaemia/insulinaemia and associated events such as oxidative stress and inflammation. Repeated overshoot of this ‘stress-like’ postprandial response may lead to low-grade chronic inflammation, especially in individuals with an already existing metabolic syndrome. We hypothesize that the magnitude and duration of the postprandial response depend on the meal composition. Methods: In a randomized crossover design 60 subjects with metabolic syndrome traits and mean age 70 ± 5 y consumed three differently composed iso-energetic (4300 kJ) meals: a Western diet high fat (WDHF), a Western diet high carbohydrate (WDHC), and a Mediterranean diet (MED; rich in oleic acid and antioxidants) meal. Blood samples were collected at fasting and 1, 2, 3, 4, and 5 h postprandial and analysed for parameters of glucose and lipid metabolism and plasma interleukin-6. Data were analysed by linear mixed models. Results: MED and WDHF meal showed lower glycaemic response (incremental AUC (iAUC): MED = 244 min*mmol/l, WDHF = 177 min*mmol/l vs. WDHC = 293 min*mmol/l) and insulinaemic response (iAUC: MED = 86108 min*pmol/l, WDHF = 63555 min*pmol/l vs. WDHC = 108735 min*pmol/l) than WDHC meal. Magnitude of serum triglyceride increase was lowest in the WDHC meal (iAUC: 175 min*mmol/l) compared with MED (iAUC: 184 min*mmol/l) and WDHF meal (iAUC: 243 min*mmol/l). Insulin and triglycerides remained elevated after 5 h independent of meal composition. Plasma interleukin-6 significantly increased postprandial without significant differences between meals. Conclusion: In line with our hypothesis, magnitude of the postprandial response depends on the meal composition. A Mediterranean-like diet rich in unsaturated fatty acids and antioxidative compounds may diminish the risk for the development of low-grade inflammation. Disclosure of Interest: None declared.
S275 MON-P263 INCREASED AWARENESS OF OBESITY IS RELATED WITH DECREASED METABOLIC SYNDROME RISK IN OBESE CHILDREN Y. Ertaş1 *, R. Bozbulut2, E. Köksal1. 1Nutrition and Dietetics, 2 Faculty of Medicine, GAZI University, Ankara, Turkey Rationale: The prevalence of metabolic syndrome (MetS) is increasing in parallel with the increasing of obesity in childhood. Increased knowledge about obesity in children may reduce the risk of having MetS. Assessment of obesity awareness and diet quality of obese children according to MetS groups were aimed in this study. Methods: This study was consist of totally 236 children (119 male and 117 female) aged 10–14 years. Anthropometric measurements (body weight (kg), height (cm), waist circumference (cm)) and biochemical parameters (glucose, insulin, total cholesterol, LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C) and triglyceride) of the children were taken. Diagnosis of metabolic syndrome (MetS) were done according to The International Diabetes Federation (IDF) consensus definition. Having MetS was demonstrated as MetS (+) and not having was MetS (-). Obesity knowledge of children were assessed with ‘Obesity Awareness (OBA) Scale’ and diet quality were evaluated via ‘Adapted Healthy Lifestyle-Diet Index for Turkey (HLD-TR)’. Results: Median ± IQR values of age were 14.0 ± 1.25 and 12.0 ± 2.00 years for MetS (+) and MetS (−) respectively. Having MetS was higher in male gender (58.1%) than female gender. Higher median OBA index scores and HLD-TR index scores were found in Met (−) group ( p < 0.001). As the OBA index scores increased HLD-TR index scores (r = 0.265, p < 0.001), HDL-C levels (r = 0.205, p = 0.002) increased and body weight (r = −0.191, p < 0.001), waist circumference (r = −0.238, p < 0.001) and glucose levels (r = −0.221, p = 0.001) decreased. Conclusion: Increased obesity awareness were related with decreased MetS occurrence and associated health outcomes. Furthermore, diet quality were positively associated with increased obesity knowledge suggested that obesity awareness have impact for healthy nutritional behaviors in obese children. Disclosure of Interest: None declared.
MON-P264 TOTAL SERUM ANTIOXIDANT CAPACITY IN HEALTHY NORMAL WEIGHT AND ASYMPTOMATIC OVERWEIGHT ADULTS Z. Jenko Pražnikar1 *, A. Petelin1, M. Stubelj1. 1Dietetics, University of Primorska Faculty of Health Sciences, Izola, Slovenia Rationale: Obesity and overweight are major contributors to the burden of chronic disease. Both are defined as abnormal or excessive fat accumulation and by increased production of free radicals leading to oxidative stress. The aim of the present study was to evaluate whether overweight and fat accumulation is associated with serum total antioxidant capacity (TAC) in men and women, irrespective of nutritional habits, nutrient intakes, physical activity, smoking, and other confounders, which may be responsible for modifying the association between serum TAC and overweight/obesity measures. Methods: This cross-sectional study was conducted on 60 normal weight and 60 overweight adults aged 25–49. All participants underwent standard anthromorphological
MON-P262 ACUTE EFFECTS OF DIFFERENTLY COMPOSED MEALS ON POSTPRANDIAL METABOLISM IN OLDER ADULTS WITH A CVD RISK PHENOTYPE Y. B. Schönknecht1 *, S. Crommen1, B. Stoffel-Wagner2, M. Coenen3, R. Fimmers4, P. Stehle1, S. Egert1. 1Department of Nutrition and Food Sciences, University of Bonn, 2Institute of Clinical Chemistry and Clinical Pharmacology, 3Study Centre, Institute of Clinical Chemistry and Clinical Pharmacology, 4 Institute of Medical Biometry, University Hospital Bonn, Bonn, Germany Rationale: The postprandial situation is characterized by lipaemia, glycaemia/insulinaemia and associated events such as oxidative stress and inflammation. Repeated overshoot of this ‘stress-like’ postprandial response may lead to low-grade chronic inflammation, especially in individuals with an already existing metabolic syndrome. We hypothesize that the magnitude and duration of the postprandial response depend on the meal composition. Methods: In a randomized crossover design 60 subjects with metabolic syndrome traits and mean age 70 ± 5 y consumed three differently composed iso-energetic (4300 kJ) meals: a Western diet high fat (WDHF), a Western diet high carbohydrate (WDHC), and a Mediterranean diet (MED; rich in oleic acid and antioxidants) meal. Blood samples were collected at fasting and 1, 2, 3, 4, and 5 h postprandial and analysed for parameters of glucose and lipid metabolism and plasma interleukin-6. Data were analysed by linear mixed models. Results: MED and WDHF meal showed lower glycaemic response (incremental AUC (iAUC): MED = 244 min*mmol/l, WDHF = 177 min*mmol/l vs. WDHC = 293 min*mmol/l) and insulinaemic response (iAUC: MED = 86108 min*pmol/l, WDHF = 63555 min*pmol/l vs. WDHC = 108735 min*pmol/l) than WDHC meal. Magnitude of serum triglyceride increase was lowest in the WDHC meal (iAUC: 175 min*mmol/l) compared with MED (iAUC: 184 min*mmol/l) and WDHF meal (iAUC: 243 min*mmol/l). Insulin and triglycerides remained elevated after 5 h independent of meal composition. Plasma interleukin-6 significantly increased postprandial without significant differences between meals. Conclusion: In line with our hypothesis, magnitude of the postprandial response depends on the meal composition. A Mediterranean-like diet rich in unsaturated fatty acids and antioxidative compounds may diminish the risk for the development of low-grade inflammation. Disclosure of Interest: None declared.
S275 MON-P263 INCREASED AWARENESS OF OBESITY IS RELATED WITH DECREASED METABOLIC SYNDROME RISK IN OBESE CHILDREN Y. Ertaş1 *, R. Bozbulut2, E. Köksal1. 1Nutrition and Dietetics, 2 Faculty of Medicine, GAZI University, Ankara, Turkey Rationale: The prevalence of metabolic syndrome (MetS) is increasing in parallel with the increasing of obesity in childhood. Increased knowledge about obesity in children may reduce the risk of having MetS. Assessment of obesity awareness and diet quality of obese children according to MetS groups were aimed in this study. Methods: This study was consist of totally 236 children (119 male and 117 female) aged 10–14 years. Anthropometric measurements (body weight (kg), height (cm), waist circumference (cm)) and biochemical parameters (glucose, insulin, total cholesterol, LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C) and triglyceride) of the children were taken. Diagnosis of metabolic syndrome (MetS) were done according to The International Diabetes Federation (IDF) consensus definition. Having MetS was demonstrated as MetS (+) and not having was MetS (-). Obesity knowledge of children were assessed with ‘Obesity Awareness (OBA) Scale’ and diet quality were evaluated via ‘Adapted Healthy Lifestyle-Diet Index for Turkey (HLD-TR)’. Results: Median ± IQR values of age were 14.0 ± 1.25 and 12.0 ± 2.00 years for MetS (+) and MetS (−) respectively. Having MetS was higher in male gender (58.1%) than female gender. Higher median OBA index scores and HLD-TR index scores were found in Met (−) group ( p < 0.001). As the OBA index scores increased HLD-TR index scores (r = 0.265, p < 0.001), HDL-C levels (r = 0.205, p = 0.002) increased and body weight (r = −0.191, p < 0.001), waist circumference (r = −0.238, p < 0.001) and glucose levels (r = −0.221, p = 0.001) decreased. Conclusion: Increased obesity awareness were related with decreased MetS occurrence and associated health outcomes. Furthermore, diet quality were positively associated with increased obesity knowledge suggested that obesity awareness have impact for healthy nutritional behaviors in obese children. Disclosure of Interest: None declared.
MON-P264 TOTAL SERUM ANTIOXIDANT CAPACITY IN HEALTHY NORMAL WEIGHT AND ASYMPTOMATIC OVERWEIGHT ADULTS Z. Jenko Pražnikar1 *, A. Petelin1, M. Stubelj1. 1Dietetics, University of Primorska Faculty of Health Sciences, Izola, Slovenia Rationale: Obesity and overweight are major contributors to the burden of chronic disease. Both are defined as abnormal or excessive fat accumulation and by increased production of free radicals leading to oxidative stress. The aim of the present study was to evaluate whether overweight and fat accumulation is associated with serum total antioxidant capacity (TAC) in men and women, irrespective of nutritional habits, nutrient intakes, physical activity, smoking, and other confounders, which may be responsible for modifying the association between serum TAC and overweight/obesity measures. Methods: This cross-sectional study was conducted on 60 normal weight and 60 overweight adults aged 25–49. All participants underwent standard anthromorphological