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Morphologic changes in the heart in experimental myxedema
630
THE
AMERICAN
HEART
JOURNAT,
On the hasis of these correlated observations, it is fair to assume that a tliagnc1sis of transient ventricular fibrillation may be suspected in N pat,ient with A-X’ 11i,s sociation and syncopal attacks if any of these cardiac mechanisms are observe,1 to appear either prior to or suhsequent to syncopal seizures. AUTfIOK.
Webster, Bruce, and Cooke, Crispin: Morphologic Changes in the Heart in Experimental Myxedema. ilrch. Tnt. Med. 58: 269, 1936. Myxedema was readily produced in adult rabbits by total removal of the thyroid gland. In the cases of more severe involvement this was accompanied by perieardial and peritoneal effusions. The heart muselo of these myxedematous animals had an average fluid content of 81.9 per cent, as compared with 75.6 per cent in a control series of normal animals. On microscopic examination this heart muselc showeil marked degenerative changes, characterized I)y a decrease in tht* number of tilrcrs, edema, and a disappearance of the perinuclear sarcoplasm. iLlyxedema is apparently capable of producing serious myo(*ar~lial damage in tho adult rabbit. L~UTHOR.
Hochrein,
M., and f. Kreislaufforsch.
Schneyer, 28:
257,
K.:
Prognosis
of Myocardial
Infarction.
Ztschr.
1936.
Myocardial infarction is a serious concern of the cardiologist because of its high mortality and the restriction of activity in those who survive. The authors found a mortality rate of 71 per cent in their group of 226 cases. In 97 cases death o(*curred within a few days. During convalescence, 24 died of heart failure, 16 from the infarction, 7 from emboli, and 7 from secondary heart causes. There were 65 ~110 survived, but only 23 without incapacity, while 32 had dyspnea on effort, Ii had stenocardia, and 14 had edema. Of bad prognostic omen are (a) atypirral clinical and electlo~ardiograpllii: find 1ngs, (b) signs of secretory insufficiency, and (c) appearance of cardiac insufficiency. Xormal vital capacity and a rapid return of blood pressure are favorable signs. Recovery is retarded by irregular habits, sexual excesses, and emotional upsets.
Shookhoff, Charles, Douglas, Albert Time in Acute Cardiac Infarction.
H., and Rabinowitz, Meyer: Sedimentation Ann. Tnt. Med. 9: 1101, 1936.
The red blood cell sedimentation time was studied in twenty-nine eases of acute cardiac infarction. It was abnormally 1npid in all. It became rapid betweeu the second .1nd fifth days and returned to m1rmal 1~ tween the thirteenth and thirty-ninth days. An abnormal sedimentation rate may outlast the return of temperature amI leucocyte count to normal by as much as four weeks. It may be abnormal when the temperature and leucocyte count have been normal throughout. It is of great help in cases seen first several days or weeks after the oceurrencc of a cardiac infarction. It helps in the recognition of subsequent thrombosis or infection. It makes less arbitrary the duration of bed rest. QUTEuR.
Mullins, sylvania
William M.
L.: J. 39:
Age Incidence 322,
and Mortality
in Coronary
Occlusion.
Penn-
1936.
The age incidence and m.ortality of 400 cases examined fro111 the Hea1.t Depart merit of the Mercy Hospital, Pittsburgh, are tabulated. The immediate mortality 1n all eases was 9 per cent. In 80 cases seen between July, 1928, and July, 1930,
THE
AMERICAN
HEART
JOURNAT,
On the hasis of these correlated observations, it is fair to assume that a tliagnc1sis of transient ventricular fibrillation may be suspected in N pat,ient with A-X’ 11i,s sociation and syncopal attacks if any of these cardiac mechanisms are observe,1 to appear either prior to or suhsequent to syncopal seizures. AUTfIOK.
Webster, Bruce, and Cooke, Crispin: Morphologic Changes in the Heart in Experimental Myxedema. ilrch. Tnt. Med. 58: 269, 1936. Myxedema was readily produced in adult rabbits by total removal of the thyroid gland. In the cases of more severe involvement this was accompanied by perieardial and peritoneal effusions. The heart muselo of these myxedematous animals had an average fluid content of 81.9 per cent, as compared with 75.6 per cent in a control series of normal animals. On microscopic examination this heart muselc showeil marked degenerative changes, characterized I)y a decrease in tht* number of tilrcrs, edema, and a disappearance of the perinuclear sarcoplasm. iLlyxedema is apparently capable of producing serious myo(*ar~lial damage in tho adult rabbit. L~UTHOR.
Hochrein,
M., and f. Kreislaufforsch.
Schneyer, 28:
257,
K.:
Prognosis
of Myocardial
Infarction.
Ztschr.
1936.
Myocardial infarction is a serious concern of the cardiologist because of its high mortality and the restriction of activity in those who survive. The authors found a mortality rate of 71 per cent in their group of 226 cases. In 97 cases death o(*curred within a few days. During convalescence, 24 died of heart failure, 16 from the infarction, 7 from emboli, and 7 from secondary heart causes. There were 65 ~110 survived, but only 23 without incapacity, while 32 had dyspnea on effort, Ii had stenocardia, and 14 had edema. Of bad prognostic omen are (a) atypirral clinical and electlo~ardiograpllii: find 1ngs, (b) signs of secretory insufficiency, and (c) appearance of cardiac insufficiency. Xormal vital capacity and a rapid return of blood pressure are favorable signs. Recovery is retarded by irregular habits, sexual excesses, and emotional upsets.
Shookhoff, Charles, Douglas, Albert Time in Acute Cardiac Infarction.
H., and Rabinowitz, Meyer: Sedimentation Ann. Tnt. Med. 9: 1101, 1936.
The red blood cell sedimentation time was studied in twenty-nine eases of acute cardiac infarction. It was abnormally 1npid in all. It became rapid betweeu the second .1nd fifth days and returned to m1rmal 1~ tween the thirteenth and thirty-ninth days. An abnormal sedimentation rate may outlast the return of temperature amI leucocyte count to normal by as much as four weeks. It may be abnormal when the temperature and leucocyte count have been normal throughout. It is of great help in cases seen first several days or weeks after the oceurrencc of a cardiac infarction. It helps in the recognition of subsequent thrombosis or infection. It makes less arbitrary the duration of bed rest. QUTEuR.
Mullins, sylvania
William M.
L.: J. 39:
Age Incidence 322,
and Mortality
in Coronary
Occlusion.
Penn-
1936.
The age incidence and m.ortality of 400 cases examined fro111 the Hea1.t Depart merit of the Mercy Hospital, Pittsburgh, are tabulated. The immediate mortality 1n all eases was 9 per cent. In 80 cases seen between July, 1928, and July, 1930,