Morphometric analysis of late adaptation of the residual lung following pneumonectomy in young and adult rabbits

Morphometric analysis of late adaptation of the residual lung following pneumonectomy in young and adult rabbits

486 INTERNATIONAL metastases were apparent (en block with thyroidectomy at the initial surgical procedure or as a solitary procedure when metastases...

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486

INTERNATIONAL

metastases were apparent (en block with thyroidectomy at the initial surgical procedure or as a solitary procedure when metastases appear or are discovered later). Radioactive iodine was administered for treatment of pulmonary metastases. Control of these tumors was not achieved by external radiation used in 5 secondary patients who received their primary care elsewhere. Results achieved include an operative mortality of 1 in 69 procedures (1.5 per cent) with 47 patients surviving 5 years or more (a 5-year survival rate of 92.1 per cent) and 8 are living and well 20 years following treatment. Of the 12 deaths, only 3 were due to cancer of the thyroid gland; however, residual thyroid cancer was present in 8 who died of other causes. Three patients were lost to followup.--W. K. Sieber.

THORAX THE CORREC~ON OF FUNNEL CHEST IN ADOLESCENTS AND ADULTS. A NEW OPERATION. H. G.

Bruck and G. Salzer. Acta Chir. Austriaca 14 (January), 1969.

1:8-

Personal experiences, based on a series of 18 patients, with a new operative technic for correction of funnel chest are given. In cases with a deep funnel the costal cartilages are divided in the area of the pathologic angle. A transverse as well as a median stemotomy is preformed and stabilization of the mobilized sternum achieved by use of a dermisgraft, which is tightly sutured under the fragments. In cases of extensive flat depressions where a repositioning is possible, one or two pairs of Kirschner wire are drilled through the ribs and sternum, crossing in the midline. They are bent into some overcorrection and left in place for about 6 months. The importance of preserving both mammary arteries to insure sufficient blood supply is stressed. Using these technics no recurrences were seen; the functional and cosmetic results were satisfactory.-G. Brandesky. OF A LARGE CHONDROMYXOIDFIBROMA OF THE STERNUM. S. L. Teitelbaum and L.

RESECTION

Bessone. (March),

J. Thor. 1969.

Cardiov.

Surg.

57:333-340

The authors report a 17-year-old girl who underwent resection of a chondromyxoid fibroma of the sternum and remains free of recurrence 2 years later. Thirty-three chondromyxoid sarcomas of bone are reported from Barnes Hospital, 80 per cent of them in patients under 30 years of age. Initial manifestations are usually a painful mass. Locations were: long bones, 19 cases; feet, 8

ABSTRACTS

OF

PEDIATRIC

SURGERY

cases; vertebral body, 1 case; and flat bones, 5 cases. No previous reports of occurrence in the sternum were found in the Barnes’ experience nor in the literature. Although local recurrence is common and radical excision recommended, the lesion is considered benign.-J. G. Rosenkrantz.

LEIOMYOMA OF THE BRONCHUS. T. L. Taylor and

D. R. Miller. J. Thor. Cardiov. 288 (February), 1969.

Surg. 57:284-

This is a case report of leiomyoma of the bronchus in an adult and a review of the literature (21 references). Of the 22 cases reviewed from the literature, 5 patients were 18 years of age or younger. Resection has been successful, but has often required pneumonectomy.-J. G. Rosenkrantz. PULMONARY ALVEOLAR MICROLITHIASIS: LUNG FVNCI-ION IN FIVE CASES. F. J. D. Fuleihan,

R. T. Abband, Nucho. Thorax

1. P. Balikian, and C. K. V. 24:84-90 (January), 1969.

Pulmonary alveolar microlithiasis, a rare disorder, of unknown etiology, is characterized by many microscopic stones in the pulmonary alveoli. Only late in the course do symptoms of respiratory insufficiency appear. Detailed pulmonary function studies in 5 patients (ages 6, 15, 15, 17, and 17) are reported.--W. K. Sieber. MORPHOMETRIC ANALYSIS OF LATE ADAPTATION OF THE RESIDUAL LUNG FOLLOWING PNEUMONECTOMY IN YOUNG AND ADULT RABBITS. Zd.

Serj,, E. Keprt, and M. Cardiov. Surg. 57:549-557

Obru&ik. J. Thor. (April), 1969.

Right pneumonectomy was done in young (6-10 weeks old) and adult rabbits and the animals were killed 6-16 months later. Lung volumes were measured and estimates made from lung slices of volume of parenchymatous (respiratory) and nonparenchymatous (vessels, bronchi, etc.) structures. From this internal alveolar surface and number of alveoli were calculated. Mean volume of the preoperative left lung was 15 ml. and 25 ml. in young and adult rabbits, respectively. After right pneumonectomy this more than doubled, with no difference between young and adult animals. There was no evidence of increased internal alveolar surface or number of alveoli postpneumonectomy in either young or adult rabbits. The authors conclude that after pneumonectomy the lung enlarges, but does not undergo hyperplasia and that the young rabbit has no advantage over the adult rabbit in this regard.--l. G. Rosenkrantz.