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Morphotype of OSA Patients
Sleep Disorders SESSION TITLE: Sleep Disorders 2 SESSION TYPE: Original Investigation Poster PRESENTED ON: Wednesday, October 26, 2016 at 01:30 PM - 02:30 PM
Morphotype of OSA Patients Moussa Riachy MD* Rachelle Hamade MD Joelle Hobeika MD; and Ihab Ibrahim MD Hotel Dieu de France, Beirut, Lebanon PURPOSE: Compare the craniofacial morphological phenotype of subjects with and without obstructive sleep apnea (OSA) using a clinical analysis technique. METHODS: Design: Prospective observational study. Morphotype comparison of case-control groups and of matched groups for age and sex. Setting: Sleep Center in a university teaching hospital: Hotel Dieu de France. Patients: 109 subjects with OSA (Respiratory Disturbance Index RDI$ 15 /h) and 53 controls (RDI <15/ h). Interventions: craniofacial clinical measures defined and standardized are performed for each subject prior to polysomnography. RESULTS: Many craniofacial measures differentiate statistically OSA patients from control subjects morphotype at several levels of the face, mandibula, maxilla, palate level, head and neck. The main relevant parameters apart age (OR ¼ 1.04; p 0.017) are the Mallampati-dynamic (OR ¼ 1.93; p 0.024) and the perpendicular distance to the deepest point at the crico-mental distance (OR ¼ 0.49; p 0.004). After matching 1-by-1 for age and sex for 70 subjects (35 in each group), significant measured remained: Mallampati-inspiration (OR ¼ 1.80; p 0.042) and the perpendicular distance to the deepest point at the crico-mental distance (OR ¼ 0.93; p 0.042).
SLEEP DISORDERS
CONCLUSIONS: Defined craniofacial morphological aspects can differentiate between OSA and controls subjects. The dynamic Mallampati and the perpendicular distance to the deepest point at the crico-mental distance are useful to screen patients at risk for moderate-severe obstructive sleep apnea. These craniofacial measurements seem to capture the soft tissue and skeletal anatomy abnormalities. CLINICAL IMPLICATIONS: Models including specific morphotype measures including the dynamic Mallampati and the perpendicular distance to the deepest point at the crico-mental distance in association to other known risk factors as age, sex, hight, neck circumference, Epworth and Berlin score are of big help to screen moderate to severe OSA. This high risk population will perform a definitive diagnosis with polysomnography earlier in life. This needs to be validated prospectively on a general population. DISCLOSURE: The following authors have nothing to disclose: Moussa Riachy, Rachelle Hamade, Joelle Hobeika, Ihab Ibrahim No Product/Research Disclosure Information DOI:
http://dx.doi.org/10.1016/j.chest.2016.08.1396
Copyright ª 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
1282A
[
150#4S CHEST OCTOBER 2016
]
Morphotype of OSA Patients Moussa Riachy MD* Rachelle Hamade MD Joelle Hobeika MD; and Ihab Ibrahim MD Hotel Dieu de France, Beirut, Lebanon PURPOSE: Compare the craniofacial morphological phenotype of subjects with and without obstructive sleep apnea (OSA) using a clinical analysis technique. METHODS: Design: Prospective observational study. Morphotype comparison of case-control groups and of matched groups for age and sex. Setting: Sleep Center in a university teaching hospital: Hotel Dieu de France. Patients: 109 subjects with OSA (Respiratory Disturbance Index RDI$ 15 /h) and 53 controls (RDI <15/ h). Interventions: craniofacial clinical measures defined and standardized are performed for each subject prior to polysomnography. RESULTS: Many craniofacial measures differentiate statistically OSA patients from control subjects morphotype at several levels of the face, mandibula, maxilla, palate level, head and neck. The main relevant parameters apart age (OR ¼ 1.04; p 0.017) are the Mallampati-dynamic (OR ¼ 1.93; p 0.024) and the perpendicular distance to the deepest point at the crico-mental distance (OR ¼ 0.49; p 0.004). After matching 1-by-1 for age and sex for 70 subjects (35 in each group), significant measured remained: Mallampati-inspiration (OR ¼ 1.80; p 0.042) and the perpendicular distance to the deepest point at the crico-mental distance (OR ¼ 0.93; p 0.042).
SLEEP DISORDERS
CONCLUSIONS: Defined craniofacial morphological aspects can differentiate between OSA and controls subjects. The dynamic Mallampati and the perpendicular distance to the deepest point at the crico-mental distance are useful to screen patients at risk for moderate-severe obstructive sleep apnea. These craniofacial measurements seem to capture the soft tissue and skeletal anatomy abnormalities. CLINICAL IMPLICATIONS: Models including specific morphotype measures including the dynamic Mallampati and the perpendicular distance to the deepest point at the crico-mental distance in association to other known risk factors as age, sex, hight, neck circumference, Epworth and Berlin score are of big help to screen moderate to severe OSA. This high risk population will perform a definitive diagnosis with polysomnography earlier in life. This needs to be validated prospectively on a general population. DISCLOSURE: The following authors have nothing to disclose: Moussa Riachy, Rachelle Hamade, Joelle Hobeika, Ihab Ibrahim No Product/Research Disclosure Information DOI:
http://dx.doi.org/10.1016/j.chest.2016.08.1396
Copyright ª 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
1282A
[
150#4S CHEST OCTOBER 2016
]