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INS; years of age and older
Abstracts / Journal of the Neurological Sciences 333 (2013) e152–e214
Conclusions: More frequent ENDs have been reported in linear patterns than skipped and lacunar patterns in small deep infarction. We found the usefulness of coronal DWI in predicting early clinical course and in depicting small deep infarction. doi:10.1016/j.jns.2013.07.672
Abstract — WCN 2013 No: 328 Topic: 3 — Stroke Mortality-related factors in ischemic stroke patients 80 years of age and older Y. Kaplan, O. Kamisli, S. Kamisli, S. Altınayar, C. Ozcan. Neurology, Inonu University, Malatya, Turkey Background: To date, many variables that affect the early and late prognosis in stroke patients have been reported. Many of these factors cannot be changed, such as oldest age. It is important to determine the changeable and non-changeable factors related to disability and death in the oldest age groups. Objective: The aim was to investigate mortality-related factors in ischemic stroke patients 80 years of age and older. Methods: We reviewed all ischemic stroke patients admitted to our clinic between January 2010 and January 2012. The patients' database information was retrospectively analyzed. One hundred and ten patients aged older than 80 years with ischemic stroke were included in the study. The patients were divided into two groups based on survival. Age, gender, recurrent stroke, risk factors, clinical syndrome, etiology, radiographic localization, duration of hospitalization, and presence of systemic complications were accepted as mortality-related prognostic factors. The groups were compared according to these prognostic factors. Results: In the clinical follow-up, 58 (52.7%) patients died; 65.5% died of neurological causes, and 31% died of systemic complications. No significant differences existed between the two groups in age, gender, risk factors, recurrent stroke, or etiology. The frequency of total anterior circulation infarct syndrome was much higher in deceased than living patients (50% and 36.5% respectively; p b 0.05). Deceased patients had a statistically significantly higher incidence of total MCA infarct and systemic complications than did living patients (p b 0.05). Conclusion: Starting appropriate treatment and care initiatives as soon as possible is also very necessary in the oldest stroke patients. doi:10.1016/j.jns.2013.07.673
Abstract — WCN 2013 No: 337 Topic: 3 — Stroke Prevalence of cardioembolic stroke increased significantly in Chinese population in the past 10 years Y. Sooa, X. Huanga,b, X.Y. Chena, N. Chana, V. Ipa, L. Aua, F. Fana, A. Chana, T. Leunga, L.K.S. Wonga. aDepartment of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, Hong Kong; bDepartment of Neurology, Houjie Hospital, Dongguan, China Background: Atrial fibrillation-related cardioembolic stroke (AF-CE) is a major cause of cardioembolism, which may be potentially preventable with anti-coagulation. Objective: The aim of the study was to evaluate the changes in the prevalence of AF-CE over the past ten years in Chinese population.
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Patients and methods: We evaluated the prevalence of AF-CE and risk factor profile from data collected prospectively from Prince of Wales Hospital Stroke Registry in 1999, 2004 and 2009. Results: Total 2744 patients were admitted for ischaemic stroke or transient ischaemic attack in these three years — 946 patients in 1999, 887 in 2004 and 911 in 2009. There was no significant difference in the mean age of patients (71.2 ± 11.3 years, 70.7 ± 12.8 years, and 70.8 ± 12.5 years respectively, p = 0.644). The number of AF-CE increased significantly — 92 patients (9.7%) in 1999, 104 patients (11.7%) in 2004 and 216 patients (23.7%) in 2009 (p b 0.001). Among patients with atrial fibrillation, the mean CHADS score prior to the index stroke was 2.7 ± 1.3 in 1999, 3.0 ± 1.3 in 2004 and 2.2 ± 1.3 in 2009. The percentage of patients who were on warfarin before admission was 21.7% in 1999, 23.1% in 2004 and 13.0% in 2009. Conclusion: Over the past 10 years, the prevalence of AF-CE has increased significantly in Chinese population. Although most of the patients with atrial fibrillation had CHADS score 3 2, only a minority of them were anticoagulated before admission. Raising the awareness of this potentially preventable stroke subtype is warranted in Chinese population. doi:10.1016/j.jns.2013.07.674
Abstract — WCN 2013 No: 369 Topic: 3 — Stroke The safety and efficacy of the intravenous recombinant tissue plasminogen activator for the ischemic stroke patients in community based hospital J. Jounga, I.U. Songb, D. Joungc. aNeurology, Soonchunhyang University, Gumi-City, Republic of Korea; bNeurology, Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Republic of Korea; cNeurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Republic of Korea Background: The results of the NINDS r-tPA Stroke Trial generated considerable hope, but also concerns about whether the results of the NINDS r-tPA Stroke Trial can be replicated in routine clinical practice. We studied whether r-tPA infusion could be applied in a community based hospital with safety and efficacy. Methods: We analyzed retrospectively the data of thirty-three patients with acute ischemic stroke treated with intravenous r-tPA, from Feb. 2003 to Dec. 2006. Safety was evaluated by intracranial hemorrhage, symptomatic intracranial hemorrhage and mortality. Clinical neurologic status was measured by NIHSS at baseline, 24 h, and 7 days after r-tPA treatment. Efficacy was assessed by the response rate of r-tPA using improvement of NIHSS by 4 or more points at 24 h after treatment and the long term outcome with the modified Rankin scale at 3 months after stroke. Results: The Median NIHSS was 18. Mean onset to needle time was 140 ± 30 min. Among the 33 patients, 10 patients had intracranial hemorrhage. Two patients had symptomatic intracranial hemorrhage but no death occurred. 15 patients showed improvement of NIHSS by 4 or more points at 24 h after r-tPA. 12 patients showed good outcome at 3 months. 9 patients had no or minimal symptoms,7 patients had mild to moderate disability, 10 patients had severe disability and 7 patients were died. Conclusions: The efficacy and safety of intravenous r-tPA for acute ischemic stroke in the community based hospital mirror the results of the NINDS stroke trial. doi:10.1016/j.jns.2013.07.675
Conclusions: More frequent ENDs have been reported in linear patterns than skipped and lacunar patterns in small deep infarction. We found the usefulness of coronal DWI in predicting early clinical course and in depicting small deep infarction. doi:10.1016/j.jns.2013.07.672
Abstract — WCN 2013 No: 328 Topic: 3 — Stroke Mortality-related factors in ischemic stroke patients 80 years of age and older Y. Kaplan, O. Kamisli, S. Kamisli, S. Altınayar, C. Ozcan. Neurology, Inonu University, Malatya, Turkey Background: To date, many variables that affect the early and late prognosis in stroke patients have been reported. Many of these factors cannot be changed, such as oldest age. It is important to determine the changeable and non-changeable factors related to disability and death in the oldest age groups. Objective: The aim was to investigate mortality-related factors in ischemic stroke patients 80 years of age and older. Methods: We reviewed all ischemic stroke patients admitted to our clinic between January 2010 and January 2012. The patients' database information was retrospectively analyzed. One hundred and ten patients aged older than 80 years with ischemic stroke were included in the study. The patients were divided into two groups based on survival. Age, gender, recurrent stroke, risk factors, clinical syndrome, etiology, radiographic localization, duration of hospitalization, and presence of systemic complications were accepted as mortality-related prognostic factors. The groups were compared according to these prognostic factors. Results: In the clinical follow-up, 58 (52.7%) patients died; 65.5% died of neurological causes, and 31% died of systemic complications. No significant differences existed between the two groups in age, gender, risk factors, recurrent stroke, or etiology. The frequency of total anterior circulation infarct syndrome was much higher in deceased than living patients (50% and 36.5% respectively; p b 0.05). Deceased patients had a statistically significantly higher incidence of total MCA infarct and systemic complications than did living patients (p b 0.05). Conclusion: Starting appropriate treatment and care initiatives as soon as possible is also very necessary in the oldest stroke patients. doi:10.1016/j.jns.2013.07.673
Abstract — WCN 2013 No: 337 Topic: 3 — Stroke Prevalence of cardioembolic stroke increased significantly in Chinese population in the past 10 years Y. Sooa, X. Huanga,b, X.Y. Chena, N. Chana, V. Ipa, L. Aua, F. Fana, A. Chana, T. Leunga, L.K.S. Wonga. aDepartment of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, Hong Kong; bDepartment of Neurology, Houjie Hospital, Dongguan, China Background: Atrial fibrillation-related cardioembolic stroke (AF-CE) is a major cause of cardioembolism, which may be potentially preventable with anti-coagulation. Objective: The aim of the study was to evaluate the changes in the prevalence of AF-CE over the past ten years in Chinese population.
e161
Patients and methods: We evaluated the prevalence of AF-CE and risk factor profile from data collected prospectively from Prince of Wales Hospital Stroke Registry in 1999, 2004 and 2009. Results: Total 2744 patients were admitted for ischaemic stroke or transient ischaemic attack in these three years — 946 patients in 1999, 887 in 2004 and 911 in 2009. There was no significant difference in the mean age of patients (71.2 ± 11.3 years, 70.7 ± 12.8 years, and 70.8 ± 12.5 years respectively, p = 0.644). The number of AF-CE increased significantly — 92 patients (9.7%) in 1999, 104 patients (11.7%) in 2004 and 216 patients (23.7%) in 2009 (p b 0.001). Among patients with atrial fibrillation, the mean CHADS score prior to the index stroke was 2.7 ± 1.3 in 1999, 3.0 ± 1.3 in 2004 and 2.2 ± 1.3 in 2009. The percentage of patients who were on warfarin before admission was 21.7% in 1999, 23.1% in 2004 and 13.0% in 2009. Conclusion: Over the past 10 years, the prevalence of AF-CE has increased significantly in Chinese population. Although most of the patients with atrial fibrillation had CHADS score 3 2, only a minority of them were anticoagulated before admission. Raising the awareness of this potentially preventable stroke subtype is warranted in Chinese population. doi:10.1016/j.jns.2013.07.674
Abstract — WCN 2013 No: 369 Topic: 3 — Stroke The safety and efficacy of the intravenous recombinant tissue plasminogen activator for the ischemic stroke patients in community based hospital J. Jounga, I.U. Songb, D. Joungc. aNeurology, Soonchunhyang University, Gumi-City, Republic of Korea; bNeurology, Catholic University of Korea, Incheon St. Mary's Hospital, Incheon, Republic of Korea; cNeurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Republic of Korea Background: The results of the NINDS r-tPA Stroke Trial generated considerable hope, but also concerns about whether the results of the NINDS r-tPA Stroke Trial can be replicated in routine clinical practice. We studied whether r-tPA infusion could be applied in a community based hospital with safety and efficacy. Methods: We analyzed retrospectively the data of thirty-three patients with acute ischemic stroke treated with intravenous r-tPA, from Feb. 2003 to Dec. 2006. Safety was evaluated by intracranial hemorrhage, symptomatic intracranial hemorrhage and mortality. Clinical neurologic status was measured by NIHSS at baseline, 24 h, and 7 days after r-tPA treatment. Efficacy was assessed by the response rate of r-tPA using improvement of NIHSS by 4 or more points at 24 h after treatment and the long term outcome with the modified Rankin scale at 3 months after stroke. Results: The Median NIHSS was 18. Mean onset to needle time was 140 ± 30 min. Among the 33 patients, 10 patients had intracranial hemorrhage. Two patients had symptomatic intracranial hemorrhage but no death occurred. 15 patients showed improvement of NIHSS by 4 or more points at 24 h after r-tPA. 12 patients showed good outcome at 3 months. 9 patients had no or minimal symptoms,7 patients had mild to moderate disability, 10 patients had severe disability and 7 patients were died. Conclusions: The efficacy and safety of intravenous r-tPA for acute ischemic stroke in the community based hospital mirror the results of the NINDS stroke trial. doi:10.1016/j.jns.2013.07.675