Inl. J. B~ochem. Vol 17. No 12, pp. 13X3 13X4. 1985 Pergamon Press Ltd. Prmted m Great Briran
BOOK REVIEWS Multiple Choice Questions in Biochemistry-by H. HASSAL, A. J. TURNER and E. J. WOOD. 249 pp. 1985. Pitman, London/Urban & Schwarzenberg, MD, U.S.A. $11.50.
Secondary Metabolism in Microorganisms, Plants and Animals, 2nd revised and enlarged edition-by M. LUCKNER. 576 pp. 1984. Springer-Verlag, Berlin. DM 124; $43.60.
This is a very good set of MCQ because the authors give detailed and full answers to the questions and go into details why the different alternatives are right or wrong. In this way the student who has made the incorrect choice can learn why it is incorrect and why the other answers are valid or invalid. This book provides an excellent method for the reader to check his knowledge of basic biochemistry since it is only too easy to read through a standard text book and think that one knows and understands what is written. These MCQs and their detailed answers will make it clear what you know and understand. It provides an excellent revision course in basic biochemistry suitable for scientists and medical students.
Primary metabolism is concerned with energy production and the synthesis of the major structural components of cells and tissues. Secondary metabolites are such compounds as alkanes, eicosanoids, tetraketids, isoprenoids, shikimic acid, quinolines, porphyrins, erotic acid, pyrrolizidines. indole alkylamines, ergolines, kynurenic acid, melanins, cinnamic acid, coumarins. lignins etc. This volume describes the enzymes involved in the production of second metabolites, the methods used in their investigation, their synthesis and breakdown, their role in the living system. The first English edition of this work appeared in 1970. In this new edition the material has been brought up to date and is an excellent source if you want to trace artemesia lactone, carlina oxide, safynol, narwedine, mescaline, capsaicin or many other of these tantalizing compounds. It shows there is more to living things than DNA, RNA and glucose.
HPLC in Nucleic Acid Research; Methods and Applications -Edited by P. R. BROWN. 403 pp. 1984. Dekker, New York, $59.75 (USA & Canada); $71.50 (other countries). High performance liquid chromatography has led to rapid and repeatable systems of purification and analysis of nucleic acids. This multi-author volume starts with an overview of nucleic acid research and the structure. properties and chromatographic behaviour of nucleic acid components. The two main actions of the book are Methodology (sample preparation. chromatography, peak identification, quantitative analysis, microbore columns. detection systems and mobile phase control) and Applications (nucleic acid, oligonucleotides, free nucleotides in biological samples, cyclic nucleotides, enzyme assays. nucleotide coenzymes, pyrimidine and purine antimetabolite drugs, methylxanthine drugs. nucleic acid constituents in disease process). This is Volume 28 in the Dekker series Chromatogruphic Sciencr series and it maintains the high standard of the previous volumes.
DNA Repair-E. C. FKIEI~BERC;.614 pp. New York. $39.95.
1985. Freeman,
The Adaptive Role of Lipids in Biological Systems-by N. HADLEY. 319 pp. 1985. Wiley Interscience. Chichester, U.K. f50.60. As a result of the very good analytical methods available for the study of lipids we know a great deal about the role and variability of lipids in biological systems. This singleauthor volume provides an excellent readable account of the role that lipids have in membrane structure and composition; the way the lipid composition in the membranes alters as animals adapt to different temperatures; their role in nerve membranes; in waterproof waxing of surfaces and control of permeability; as a source of energy; in heat production and thermal insulation; their role in buoyancy; in communication pheromones and semichemicals; in pulmonary surfactants and lubricants. This book will interest biochemists. biologists, ecologists, physiologists and chemists in the dynamism of the fats of life.
The Biosynthesis of Polysaccharides-by 354 pp. 1984. Macmillan, New York.
Ionizing radiation, ultraviolet light, X-rays. chemical agents and spontaneous damage all can affect DNA leading to breakage and faulty copies. Over the last 30 years there has been extensive research in DNA damage and the extent to which cells have a mechanism for the repair of such damage. This textbook provides an excellent account of these mechanisms. The main chapter headings are: DNA damage; DNA repair by reversal of damage; DNA glycosidases and AP endonucleases; Incision of DNA; Postincision events and mismatch repair in Prokaryotic cells and Mammalian cells; DNA damage tolerance in Prokaryotic and Eukaryotic cells; DNA damage and human disease. The text is well-written and easy to read. It has excellent illustrations in two colours. There are detailed references after each chapter. This book lives up to the high standards we have come to expect from Freeman and will become the first source that readers interested in DNA damage and repair will consult. 1383
R. W. STODDART. $44.50.
Though polysaccharides are often thought of just in terms of storage materials such as starch and glycogen, modern research has shown that they are much more variable in size, form and function and that they play an important role in cell structure, cell recognition and immunological patterns. This volume written by one author describes these important functions. The main chapter headings are: The nature of polysaccharides; Sugar nucleotides and cyclitols: Glycosylation in bacteria: Glycoprotein and glycolipid assembly;. Polysaccharide assembly; Cytological aspects of glycosyl transfer in eukaryotes; Pathological aspects of glycosylation. The book will be useful to advanced students and research workers.
The Biology of Glycoproteins-Edited by R. J. IVATT. 449 pp. 1984. Plenum Press. New York. S59.50. Glycoproteins
function
to glue cells together.
to provide