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MYOEPITHELIOMA OF THE SOFT PALATE
OOOO Volume 129, Number 1 MYOEPITHELIOMA OF THE SOFT PALATE. CAROLINA EMERICK DA SILVA RANGEL, LARA DINIZ SALVIANO, LIVIA RAMALHO CRESCENCIO, MARIA CAROLINA DE LIMA JACY MONTEIRO BARKI, RENATA TUCCI, PRISCILA ^ RODRIGUEZ CAMARA and, REBECA DE SOUZA AZEVEDO Myoepithelioma is an uncommon benign salivary gland tumor almost exclusively composed of myoepithelial cells. This is a case of myoepithelioma occurring in the soft palate of a 73year-old woman, who wears a complete upper denture. On intraoral examination, an ulcerated sessile normochromic swelling measuring approximately 1 cm in diameter was seen, which was present for 3 years. An incisional biopsy was performed, and the microscopic examination revealed a nonencapsulated proliferation of a variety of cells, including spindle, epithelioid, and plasmacytoid. They were arranged in nests and cords and were also dispersed within areas of hyalinized and myxoid stroma. Tumor cells were positive for smooth muscle actin, and S100 protein was in the immunohistochemical reaction, rendering the diagnosis of myoepithelioma. The patient was referred, received treatment by enucleation surgery, and is currently well with no signs of recurrence.
MULTIPLE LIPOMAS ON BILATERAL BORDER OF THE TONGUE. MARIANA ^ DES, MARIA CAROLINA DE MARINHO ARE LIMA JACY MONTEIRO, RENATA TUCCI, BRUNA LAVINAS SAYED PICCIANI, PHILLIPPE MOREIRA and, REBECA DE SOUZA AZEVEDO Lipoma is an uncommon soft tissue benign neoplasm of mouth. It is rarely in multiple locations on a single patient. This is a report of a 70-year-old black male patient with the complaint of multiple swellings on the tongue lasting 1 year. Physical examination revealed 3 well-delimited, yellow, smooth nodules located bilaterally on the border of the tongue. The main clinical hypothesis was amyloidosis. The patient presented controlled hypertension, diabetes, and any personal or family history of similar lesion. An incisional biopsy from 1 nodule was performed, and microscopic examination revealed an encapsulated proliferation of mature adipocytes, sometimes interweaving the muscle fibers, rendering the diagnosis of lipoma. The remaining lesions were excised, and the microscopic examinations were similar. The patient is well with no signs of relapse or recurrence. The present case highlighted the rarity of multiple classical lipomas occurring unassociated with lipomatosis or other systemic disease.
PLASMABLASTIC LYMPHOMA OF THE MANDIBLE: A CASE REPORT. GLAUCE e GUIMARAES PEREIRA, PABLYANNNE TEREZA LOUZADA GUEDES, WILKELLY ALVES DE LIMA, AMANDA DE OLIVEIRA MACEDO, ANA CAROLINA ^A SANTIAGO DA SILVA, FLAVIA SIROTHEAU CORRE PONTES and, HELDER ANTONIO REBELO PONTES Plasmablastic lymphoma is non-Hodgkin’s lymphoma usually found in the head and neck region. It is a rare and aggressive subtype of B-cell lymphoma that affects, in most cases, HIV-positive individuals; it has a propensity for the oral cavity,
ABSTRACTS
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presenting primary oral lesion with superficial ulceration and mass of rapid evolution as the only clinical finding. A 24-yearold seropositive man was referred to an oral pathology center presenting with a 2-month history of lesion in the left posterior mandible. Clinically, there was a lesion with no defined limits, involving teeth with a high degree of mobility. An incisional biopsy was performed. The anatomopathologic examination revealed a proliferation of diffuse neoplastic cells, and immunohistochemical reactions were positive for leukocyte common antigen and CD-138, showed high Ki-67, and were negative for CD-20 and CD-3, concluding the diagnosis of plasmablastic lymphoma. The patient was referred to a hematology center to start treatment.
JUVENILE OSSIFYING FIBROMA AND FIBROUS DYSPLASIA: A CASE REPORT OF A COMPLEX DIFFERENTIAL DIAGNOSIS. MALENA REGINA DE FREITAS E. SILVA, FRANCISCO ^ ARTUR FORTE OLIVEIRA, PAULO GOBERLANIO DE e BARROS SILVA, TACIO PINHEIRO BEZERRA, JOAO e PAULO VELOSO PERDIGAO, CLARISSA PESSOA FERNANDES and, FABRICIO BITU SOUSA The authors describe a case report of a 10-year-old female patient with a painless, rapid, progressive, expansive swelling in the anterior mandible region. Radiographically, the lesion was a unilocular radiolucency with well-delineated margin, "ground glass" appearance, and 32 and 33 teeth roots displacement. Incisional biopsy was performed, and result of juvenile ossifying fibroma (JOF) was obtained. Surgical resection of the lesion and involved bone was performed, but histopathologic feature of the surgical specimen was consistent with fibrous dysplasia (FD). In a 3-month follow-up time, the patient presents no recurrence. Differential diagnosis in fibro-osseous lesions may be difficult to establish. Margin definitions, fibrous capsule presence, and analysis of immature bone, may be relevant in differential diagnosis of FD and JOF. However, when these lesions have any atypical presentation, FD or JOF characteristics may mimic themselves histologically and radiographically.
CENTRAL GIANT CELL LESION TREATED WITH CORTICOSTEROID—A CASE REPORT. CAROLINA RODRIGUES TEOFILO, ROBERTA BARROSO CAVALCANTE, NAYANA OLIVEIRA AZEVEDO, LIGIA HELENA ALMEIDA PINHEIRO, RICARDO FRANKLIN GONDIM, RAFAEL LIMA VERDE OSTERNE and, RENATO LUIZ MAIA NOGUEIRA Central giant cell lesions (CGCL) are proliferative nonneoplastic lesions more frequently presented in young female patients. Treatment often requires aggressive resection, which leads to major defects of the jaws. The authors present a CGCL case report treated with intralesional corticosteroid injection. A 24-year-old woman presenting no important medical condition had a chief complaint of a painless expansion swelling in the teeth 34 to 36 region, without alteration on oral mucosa color. Radiographically, a multilocular, radiolucent, well-defined margin measuring about 5 £ 6 cm was identified. The incisional biopsy was performed to establish CGCL histologic diagnosis. The patient was successfully treated with 10 sessions of intralesional administration of corticosteroid (triamcinolone acetonide + articaine), distributed in all
MULTIPLE LIPOMAS ON BILATERAL BORDER OF THE TONGUE. MARIANA ^ DES, MARIA CAROLINA DE MARINHO ARE LIMA JACY MONTEIRO, RENATA TUCCI, BRUNA LAVINAS SAYED PICCIANI, PHILLIPPE MOREIRA and, REBECA DE SOUZA AZEVEDO Lipoma is an uncommon soft tissue benign neoplasm of mouth. It is rarely in multiple locations on a single patient. This is a report of a 70-year-old black male patient with the complaint of multiple swellings on the tongue lasting 1 year. Physical examination revealed 3 well-delimited, yellow, smooth nodules located bilaterally on the border of the tongue. The main clinical hypothesis was amyloidosis. The patient presented controlled hypertension, diabetes, and any personal or family history of similar lesion. An incisional biopsy from 1 nodule was performed, and microscopic examination revealed an encapsulated proliferation of mature adipocytes, sometimes interweaving the muscle fibers, rendering the diagnosis of lipoma. The remaining lesions were excised, and the microscopic examinations were similar. The patient is well with no signs of relapse or recurrence. The present case highlighted the rarity of multiple classical lipomas occurring unassociated with lipomatosis or other systemic disease.
PLASMABLASTIC LYMPHOMA OF THE MANDIBLE: A CASE REPORT. GLAUCE e GUIMARAES PEREIRA, PABLYANNNE TEREZA LOUZADA GUEDES, WILKELLY ALVES DE LIMA, AMANDA DE OLIVEIRA MACEDO, ANA CAROLINA ^A SANTIAGO DA SILVA, FLAVIA SIROTHEAU CORRE PONTES and, HELDER ANTONIO REBELO PONTES Plasmablastic lymphoma is non-Hodgkin’s lymphoma usually found in the head and neck region. It is a rare and aggressive subtype of B-cell lymphoma that affects, in most cases, HIV-positive individuals; it has a propensity for the oral cavity,
ABSTRACTS
e127
presenting primary oral lesion with superficial ulceration and mass of rapid evolution as the only clinical finding. A 24-yearold seropositive man was referred to an oral pathology center presenting with a 2-month history of lesion in the left posterior mandible. Clinically, there was a lesion with no defined limits, involving teeth with a high degree of mobility. An incisional biopsy was performed. The anatomopathologic examination revealed a proliferation of diffuse neoplastic cells, and immunohistochemical reactions were positive for leukocyte common antigen and CD-138, showed high Ki-67, and were negative for CD-20 and CD-3, concluding the diagnosis of plasmablastic lymphoma. The patient was referred to a hematology center to start treatment.
JUVENILE OSSIFYING FIBROMA AND FIBROUS DYSPLASIA: A CASE REPORT OF A COMPLEX DIFFERENTIAL DIAGNOSIS. MALENA REGINA DE FREITAS E. SILVA, FRANCISCO ^ ARTUR FORTE OLIVEIRA, PAULO GOBERLANIO DE e BARROS SILVA, TACIO PINHEIRO BEZERRA, JOAO e PAULO VELOSO PERDIGAO, CLARISSA PESSOA FERNANDES and, FABRICIO BITU SOUSA The authors describe a case report of a 10-year-old female patient with a painless, rapid, progressive, expansive swelling in the anterior mandible region. Radiographically, the lesion was a unilocular radiolucency with well-delineated margin, "ground glass" appearance, and 32 and 33 teeth roots displacement. Incisional biopsy was performed, and result of juvenile ossifying fibroma (JOF) was obtained. Surgical resection of the lesion and involved bone was performed, but histopathologic feature of the surgical specimen was consistent with fibrous dysplasia (FD). In a 3-month follow-up time, the patient presents no recurrence. Differential diagnosis in fibro-osseous lesions may be difficult to establish. Margin definitions, fibrous capsule presence, and analysis of immature bone, may be relevant in differential diagnosis of FD and JOF. However, when these lesions have any atypical presentation, FD or JOF characteristics may mimic themselves histologically and radiographically.
CENTRAL GIANT CELL LESION TREATED WITH CORTICOSTEROID—A CASE REPORT. CAROLINA RODRIGUES TEOFILO, ROBERTA BARROSO CAVALCANTE, NAYANA OLIVEIRA AZEVEDO, LIGIA HELENA ALMEIDA PINHEIRO, RICARDO FRANKLIN GONDIM, RAFAEL LIMA VERDE OSTERNE and, RENATO LUIZ MAIA NOGUEIRA Central giant cell lesions (CGCL) are proliferative nonneoplastic lesions more frequently presented in young female patients. Treatment often requires aggressive resection, which leads to major defects of the jaws. The authors present a CGCL case report treated with intralesional corticosteroid injection. A 24-year-old woman presenting no important medical condition had a chief complaint of a painless expansion swelling in the teeth 34 to 36 region, without alteration on oral mucosa color. Radiographically, a multilocular, radiolucent, well-defined margin measuring about 5 £ 6 cm was identified. The incisional biopsy was performed to establish CGCL histologic diagnosis. The patient was successfully treated with 10 sessions of intralesional administration of corticosteroid (triamcinolone acetonide + articaine), distributed in all