NAFAZATROM IN THROMBOCYTOPENIC PURPURA

498 KONG IN HONG COT DEATH " XBD=2432 XBD=1381 XHG=2356 XBD=1476 XBD=1568 XBD=1683 XBD=1735 XBD=1778 XBD=1899 XBD=2086 XBD=2253 XBD=2331 XHG=1328 XHG=1409 XHG=1502 XHG=1596 XHG=1709 XHG=1762 XHG=1805 XHG=1926 XHG=2114 XHG=2279 YBD=312 YBD=305 YBD=306 YHG=278>the YHG=277>idea YHG=278>that YHG=277>there YHG=277>is YHG=286>a YHG=277>lower YHG=277>incidence YHG=282>amongst YHG=285>our YHG=275>Asian " XBD=1524 XBD=1731 XBD=1824 XBD=2018 XBD=2172 XBD=2280 XBD=2373 XBD=2433 XHG=1329 XHG=1566 XHG=1771 XHG=1863 XHG=2057 XHG=2211 XHG=2315 XHG=2404 YBD=358 YBD=355 YBD=356 YBD=357 YBD=349 YHG=321>population. YHG=321>However, YHG=320>the YHG=320>Leicester YHG=320>figures YHG=328>may YHG=320>also YHG=322>be " XBD=1226 XBD=245 XHG=802 XBD=331 XBD=420 XBD=560 XBD=626 XBD=788 XBD=963 XBD=1042 XBD=1105 XBD=1140 XHG=129 XHG=260 XHG=343 XHG=434 XHG=573 XHG=639 XHG=974YBD=376 XHG=1055 XHG=1120 XHG=1153 YBD=371 YBD=370 YBD=376 YBD=373 YBD=375 YBD=376 YHG=343>SIR,-I YHG=343>read YHG=343>with YHG=343>interest YHG=341>the YHG=347>apparent YHG=340>suspicion YHG=340>(Jan YHG=340>25, YHG=348>p YHG=340>214) " XBD=1616 XBD=1766 XBD=1825 XBD=2110 XBD=2161 XBD=2292 XHG=1329 XHG=1635 XHG=1786 XHG=1837 XHG=2129 XHG=2180 XHG=2310 YBD=402 YBD=394 YBD=401 YBD=393 YBD=392 YBD=400 YHG=365>unrepresentative YHG=365>because YHG=364>of YHG=365>under-reporting YHG=364>in YHG=363>certain YHG=364>religious " XBD=2434 XBD=171 XHG=881 XBD=288 XBD=460 XBD=616 XBD=821 XBD=874 XBD=933 XBD=1007 XBD=1181 XBD=1233 XHG=93 XHG=184 XHG=301 XHG=474 XHG=631 XHG=836 XHG=947 XHG=1020 XHG=1196 YBD=414 YBD=414 YBD=413 YBD=419 YBD=412 YBD=412 YBD=411 YHG=386>with YHG=386>which YHG=385>Professor YHG=384>Davies’s YHG=383>description YHG=383>of YHG=384>the YHG=384>low YHG=383>incidence YHG=382>of " XBD=1447 XBD=1492 XBD=1597 XBD=1725 XHG=1331 XHG=1459 XHG=1505 XHG=1608 XHG=1738 YBD=438 YBD=446 YHG=418>groups YHG=416>to YHG=409>avoid YHG=408>official YHG=417>necropsy. "" XBD=1900 XBD=144 XBD=258 XBD=309 XBD=426 XBD=552 XBD=603 XBD=716 XBD=885 XBD=1032 XBD=1177 XBD=1227 XHG=94 XHG=165 XHG=277 XHG=329 XHG=445 XHG=578 XHG=621 XHG=736 XHG=907 XHG=1051 XHG=1195 YBD=457 YBD=456 YBD=463 YBD=462 YBD=455 YBD=463 YBD=455 YHG=435>cot YHG=428>death YHG=429>in YHG=428>Hong YHG=420>Kongl YHG=427>is YHG=427>being YHG=427>received. YHG=427>Having YHG=427>worked YHG=427>in XBD=1470 XBD=1506 XBD=1558 XBD=1716 XBD=1758 XBD=1900 XBD=2036 XBD=2168 XBD=2375 XBD=2435 XHG=1366 XHG=1480 XHG=1516 XHG=1569 XHG=1725 XHG=1769 XHG=1912 XHG=2049 XHG=2178 XHG=2382 YBD=482 YBD=489 YBD=488 YBD=481 YHG=453>There YHG=453>is YHG=462>no YHG=452>evidence YHG=459>to YHG=459>support YHG=451>Davies’ YHG=452>further YHG=451>speculations YHG=453>that " XBD=1228 XBD=278 XHG=908 XBD=320 XBD=426 XBD=531 XBD=601 XBD=643 XBD=704 XBD=787 XBD=811 XBD=898 XBD=985 XBD=1092 XBD=1166 XHG=94 XHG=288 XHG=330 XHG=435 XHG=540 XHG=610 XHG=651 XHG=712 XHG=798 XHG=821 XHG=995 XHG=1101 XHG=1175 YBD=507 YBD=497 YBD=505 YBD=506 YBD=504 YBD=498 YBD=499 YBD=499 YBD=499 YBD=500 YHG=471>paediatrics YHG=471>Hong YHG=470>Kong YHG=470>and YHG=470>in YHG=470>the YHG=470>UK, YHG=470>I YHG=470>have YHG=471>little YHG=471>doubt YHG=470>that YHG=470>the " XBD=2436 XBD=1430 XBD=1523 XBD=1675 XBD=1808 XBD=1897 XBD=1960 XBD=2112 XBD=2203 XBD=2247 XBD=2308 XHG=1332 XHG=1442 XHG=1536 XHG=1686 XHG=1820 XHG=1907 XHG=1972 XHG=2123 XHG=2214 XHG=2258 XHG=2319 YBD=525 YBD=533 YBD=524 YBD=523 YBD=532 YHG=497>either YHG=497>close YHG=497>parental YHG=503>contact YHG=496>with YHG=496>the YHG=496>sleeping YHG=496>baby YHG=504>or YHG=495>the YHG=495>sleeping |>" " XBD=241 XBD=433 XBD=626 XBD=855 XBD=947 XBD=1094 XBD=1228 XBD=696 XHG=95 XHG=273 XHG=464 XHG=718 XHG=886 XHG=977 XHG=1123 XHG=655 YBD=541 YBD=541 YBD=542 YBD=542 YBD=540 YBD=543 YHG=513>different YHG=513>incidence YHG=513>described YHG=513>Chinese YHG=514>and YHG=514>British YHG=513>in YHG=514>babies " XBD=1469 XBD=1528 XBD=1660 XBD=1773 XBD=1846 XBD=2028 XBD=2087 XBD=2150 XBD=2270 XBD=2396 XBD=2437 XHG=1332 XHG=1490 XHG=1543 XHG=1681 XHG=1793 XHG=1867 XHG=2048 XHG=2101 XHG=2171 XHG=2292 XHG=2411 YBD=576 YBD=567 YBD=568 YHG=540>position YHG=539>infants YHG=539>affect YHG=539>the YHG=539>incidence YHG=539>of YHG=546>cot YHG=538>death. YHG=538>Indeed YHG=549>m |>" " XBD=333 XBD=519 XBD=559 XBD=645 XBD=710 XBD=824 XBD=910 XBD=978 XBD=1064 XBD=1230 XBD=285 XHG=300 XHG=347 XHG=534 XHG=573 XHG=661 XHG=725 XHG=838 XHG=923 XHG=992 XHG=1077 XHG=94YBD=586 YBD=583 YBD=593 YBD=584 YBD=585 YBD=591 YBD=586 YBD=595 YHG=565>vs YHG=556>2-3/1000) YHG=556>is YHG=557>real. YHG=556>An YHG=557>infant YHG=558>who YHG=557>has YHG=556>(0-03/1000 YHG=557>died YHG=557>suddenly " XBD=1467 XBD=1529 XBD=1608 XBD=1748 XBD=1854 XBD=1906 XBD=2036 XBD=2146 XBD=2261 XBD=2319 XBD=2437 XHG=1333 XHG=1476 XHG=1539 XHG=1618 XHG=1759 XHG=1863 XHG=1916 XHG=2046 XHG=2156 XHG=2269 XHG=2328 YBD=620 YBD=619 YBD=612 YBD=611 YBD=618 YHG=584>perhaps YHG=583>the YHG=583>first YHG=583>medical YHG=592>paper YHG=592>on YHG=583>sudden YHG=582>infant YHG=582>deaths YHG=582>the YHG=582>dangers " XBD=1230 XBD=159 XHG=579 XBD=196 XBD=344 XBD=389 XBD=419 XBD=568 XBD=802 XBD=1031 XBD=1143 XHG=97 XHG=171 XHG=208 XHG=357 XHG=402 XHG=431 XHG=815 XHG=1054 XHG=1153 YBD=627 YBD=634 YBD=627 YBD=628 YBD=636 YBD=629 YBD=630 YHG=599>and YHG=598>is YHG=599>brought YHG=606>to YHG=609>a YHG=600>casualty YHG=600>department’s YHG=601>resuscitation YHG=610>room YHG=601>with " XBD=1372 XBD=1617 XBD=1696 XBD=1817 XBD=1973 XBD=2148 XBD=2244 XBD=2374 XHG=1334 XHG=1383 XHG=1635 XHG=1711 XHG=1834 XHG=1990 XHG=2165 XHG=2260 XHG=2388 YBD=656 YBD=663 YBD=655 YBD=661 YBD=659 YHG=627>of YHG=627>overcrowding YHG=627>and YHG=626>babies YHG=627>sleeping YHG=626>alongside YHG=626>their YHG=633>parents YHG=636>was " XBD=2437 XBD=137 XHG=929 XBD=271 XBD=307 XBD=356 XBD=548 XBD=613 XBD=717 XBD=893 XBD=919 XBD=987 XBD=1088 XBD=1144 XBD=1231 XHG=98 XHG=147 XHG=282 XHG=317 XHG=366 XHG=558 XHG=623 XHG=727 XHG=906 XHG=997YBD=670 XHG=1098 XHG=1153 YBD=678 YBD=679 YBD=671 YBD=681 YBD=680 YBD=672 YBD=673 YBD=673 YBD=673 YHG=641>its YHG=649>parents YHG=642>is YHG=651>an YHG=643>experience YHG=650>not YHG=644>easily YHG=644>forgotten. YHG=644>I YHG=653>can YHG=644>recall YHG=645>six YHG=645>such " XBD=1524 XBD=1789 XBD=1987 XBD=2133 XBD=2207 XBD=2284 XBD=2367 XBD=2438 XHG=1335 XHG=1539 XHG=1804 XHG=2001 XHG=2146 XHG=2221 XHG=2299 XHG=2380 YBD=699 YBD=698 YBD=707 YHG=670>graphically YHG=670>described-the YHG=670>conclusion YHG=669>reached YHG=679>was YHG=669>that YHG=669>&dquo;the YHG=670>only " XBD=1232 XBD=241 XHG=725 XBD=324 XBD=408 XBD=545 XBD=646 XBD=688 XBD=715 XBD=893 XBD=1005 XBD=1113 XHG=98 XHG=252 XHG=335 XHG=418 XHG=555 XHG=656 XHG=698 XHG=903 XHG=1015 XHG=1123 YBD=721 YBD=714 YBD=722 YBD=716 YBD=724 YBD=717 YBD=717 YHG=685>episodes YHG=695>over YHG=687>nine YHG=687>months YHG=694>spent YHG=697>as YHG=697>a YHG=689>paediatric YHG=689>senior YHG=688>house YHG=688>officer " XBD=1498 XBD=1640 XBD=1752 XBD=1869 XBD=1907 XBD=1984 XBD=2050 XBD=2147 XBD=2270 XBD=2315 XBD=2405 XBD=2438 XHG=1335 XHG=1509 XHG=1653 XHG=1765 XHG=1882 XHG=1918 XHG=1996 XHG=2062 XHG=2158 XHG=2280 XHG=2327 XHG=2414 YBD=750 YBD=741 YBD=742 YBD=743 YHG=714>safeguard YHG=714>(against YHG=713>infant YHG=714>death) YHG=714>is YHG=713>that YHG=713>the YHG=713>child YHG=712>should YHG=713>be YHG=713>made YHG=721>to " XBD=1232 XBD=129 XHG=615 XBD=155 XBD=285 XBD=417 XBD=562 XBD=605 XBD=990 XBD=1076 XBD=1171 XHG=99 XHG=139 XHG=166 XHG=295 XHG=428 XHG=573 XHG=1001 XHG=1088 XHG=1180 YBD=757 YBD=757 YBD=758 YBD=765 YBD=767 YBD=759 YBD=768 YBD=760 YBD=761 YHG=735>at YHG=738>a YHG=729>district YHG=730>general YHG=730>hospital YHG=731>in YHG=732>Kingston-on-Thames, YHG=732>UK. YHG=732>Over YHG=733>the "" XBD=2439 XBD=1457 XBD=1488 XBD=1641 XBD=1706 XBD=1803 XBD=1855 XBD=2041 XBD=2238 XBD=2285 XBD=2346 XHG=1336 XHG=1472 XHG=1503 XHG=1657 XHG=1721 XHG=1817 XHG=1870 XHG=2061 XHG=2254 XHG=2298 XHG=2360 YBD=794 YBD=786 YBD=790 YBD=784 YBD=785 YBD=793 YHG=767>occupy YHG=767>a YHG=764>separate YHG=764>cot YHG=757>from YHG=758>its YHG=749>parents&dquo;.1 YHG=756>Moreover, YHG=757>in YHG=757>the YHG=766>prone XBD=169 XHG=891 XBD=223 XBD=376 XBD=422 XBD=453 XBD=587 XBD=726 XBD=876 XBD=923 XBD=1034 XBD=1143 XBD=1234 XHG=100 XHG=188 XHG=239 XHG=393 XHG=437 XHG=467 XHG=603 XHG=740 XHG=937YBD=804 XHG=1048 XHG=1157 YBD=809 YBD=801 YBD=802 YBD=803 YBD=811 YBD=812 YBD=811 YBD=811 YBD=805 YHG=779>past YHG=774>18 YHG=774>months, YHG=780>at YHG=783>a YHG=774>district YHG=775>general YHG=776>hospital YHG=776>in YHG=776>Hong YHG=776>Kong YHG=776>with " XBD=1476 XBD=1635 XBD=1699 XBD=1809 XBD=1965 XBD=2090 XBD=2268 XBD=2440 XHG=1337 XHG=1487 XHG=1646 XHG=1711 XHG=1819 XHG=1975 XHG=2100 XHG=2280 YBD=830 YBD=838 YBD=829 YBD=836 YBD=837 YHG=801>sleeping YHG=800>position, YHG=801>the YHG=800>safety YHG=800>of YHG=800>Davies YHG=800>questions, YHG=800>respiratory which "" XBD=1235 XBD=213 XBD=353 XBD=439 XBD=645 XBD=899 XBD=970 XBD=1059 XHG=101 XHG=252 XHG=391 XHG=477 XHG=683 XHG=937 XHG=1007 XHG=1098 YBD=845 YBD=846 YBD=855 YBD=849 YBD=847 YBD=848 YBD=856 YHG=816>on-call YHG=817>duties YHG=817>for YHG=818>paediatric YHG=819>resuscitation YHG=819>in YHG=819>the YHG=819>casualty XBD=1480 XBD=1532 XBD=1644 XBD=1823 XBD=1914 XBD=2255 XBD=2373 XHG=1337 XHG=1507 XHG=1558 XHG=1671 XHG=1852 XHG=1938 XHG=2281 XHG=2393 YBD=880YHG=863>traumatic YBD=872 YBD=873 YHG=844>function YHG=844>is YHG=853>more YHG=837>efficient2 YHG=844>and YHG=843>gastro-oesophageal YHG=843>reflux YHG=844>less " XBD=2440 XBD=307 XHG=746 XBD=336 XBD=427 XBD=494 XBD=584 XBD=660 XBD=733 XBD=909 XBD=1114 XHG=102 XHG=322 XHG=349 XHG=440 XHG=508 XHG=597 XHG=671 XHG=923YBD=892 YBD=897 YBD=889 YBD=890 YBD=891 YBD=899 YHG=861>department, YHG=862>I YHG=861>have YHG=868>not YHG=871>once YHG=863>had YHG=863>this YHG=863>experience. "" XBD=2441 XBD=1488 XBD=1757 XBD=1935 XBD=2049 XBD=2098 XBD=2275 XBD=2315 XHG=1337 XHG=1695 XHG=1766 XHG=1949 XHG=2057 XHG=2109 XHG=2285 XHG=2324 YBD=916 YBD=915 YBD=924 YHG=880>marked.3 YHG=888>and YHG=880>Shaddick4 YHG=887>found YHG=896>no YHG=886>difference YHG=887>in YHG=887>sleeping XBD=280 XBD=361 XBD=463 XBD=645 XBD=809 XBD=903 XBD=966 XBD=1048 XBD=1093 XBD=1192 XBD=1236 XHG=138 XHG=292 XHG=372 XHG=475 XHG=656 XHG=821 XHG=913 XHG=977 XHG=1061 XHG=1104 XHG=1204 YBD=933 YBD=942 YBD=943 YBD=934 YBD=934 YBD=934 YHG=904>Davies’s YHG=905>data YHG=905>bring YHG=906>important YHG=915>messages YHG=906>from YHG=906>the YHG=906>East YHG=913>to YHG=905>those YHG=906>in " XBD=1490 XBD=1541 XBD=1596 XBD=1701 XBD=1817 XBD=1860 XBD=2040 XBD=2126 XBD=2280 XBD=2349 XBD=2386 XBD=2441 XHG=1338 XHG=1503 XHG=1546 XHG=1608 XHG=1712 XHG=1829 XHG=1872 XHG=2048 XHG=2136 XHG=2292 XHG=2358 XHG=2395 YBD=966 YBD=963 YBD=958 YBD=959 YHG=930>positions YHG=929>of YHG=936>cot YHG=930>death YHG=930>babies YHG=940>as YHG=930>compared YHG=930>with YHG=930>controls, YHG=930>and YHG=931>in YHG=940>one " XBD=156 XBD=259 XBD=351 XBD=406 XBD=548 XBD=597 XBD=663 XBD=856 XBD=924 XBD=1189 XBD=1236 XHG=104 XHG=173 XHG=275 XHG=367 XHG=422 XHG=565 XHG=613 XHG=680 XHG=872 XHG=940 XHG=1205 YBD=981 YBD=976 YBD=978 YBD=977 YBD=985 YBD=976 YHG=947>the YHG=948>West YHG=948>with YHG=958>an YHG=949>interest YHG=949>in YHG=956>cot YHG=949>death-for YHG=949>the YHG=948>epidemiologist YHG=955>to " XBD=1376 XBD=1439 XBD=1523 XBD=1808 XBD=1941 XBD=2037 XBD=2169 XBD=2262 XHG=1338 XHG=1385 XHG=1456 XHG=1539 XHG=1824 XHG=1956 XHG=2053 XHG=2184 XHG=2278 YBD=1000 YBD=1008 YBD=1001 YBD=1002 YHG=972>of YHG=972>the YHG=972>first YHG=973>epidemiological YHG=973>studies YHG=980>most YHG=972>infants YHG=981>were YHG=972>found&dquo;face "" XBD=2442 XBD=178 XBD=323 XBD=520 XBD=1095 XBD=1240 XHG=106 XHG=199 XHG=344 XHG=860 XHG=1116 YBD=1018 YBD=1027 YBD=1025 YBD=1027 YBD=1028 cardiorespiratory YHG=989>look YHG=990>beyond YHG=984>Sheffield, YHG=991>paediatricians YHG=991>beyond XBD=1431 XBD=1482 XBD=1544 XBD=1625 XBD=1811 XBD=1923 XBD=2018 XBD=2229 XBD=2263 XBD=2404 XBD=2442 XHG=1338 XHG=1446 XHG=1492 XHG=1553 XHG=1635 XHG=1821 XHG=1933 XHG=2028 XHG=2238 XHG=2272 XHG=2412 YBD=1051 YBD=1043 YBD=1052 YBD=1044 YBD=1045 YHG=1008>up&dquo;.5 YHG=1015>In YHG=1024>my YHG=1025>own YHG=1016>interviews YHG=1017>where YHG=1023>exact YHG=1015>information YHG=1016>is YHG=1016>available YHG=1018>22 " XBD=192 XBD=289 XBD=369 XBD=549 XBD=716 XBD=886 XBD=1028 XBD=1145 XBD=1239 XHG=106 XHG=211 XHG=307 XHG=385 XHG=568 XHG=736 XHG=904 XHG=1043 XHG=1163 YBD=1064 YBD=1063 YBD=1065 YBD=1072 YBD=1071 YBD=1071 YBD=1063 YBD=1062 YHG=1035>heart YHG=1042>rates YHG=1036>and YHG=1036>breathing YHG=1043>patterns, YHG=1035>allergists YHG=1035>beyond YHG=1035>breast YHG=1034>milk " XBD=1444 XBD=1537 XBD=1652 XBD=1743 XBD=1788 XBD=1854 XBD=1965 XBD=2125 XBD=2159 XBD=2211 XBD=2301 XBD=2369 XBD=2443 XHG=1339 XHG=1457 XHG=1552 XHG=1665 XHG=1755 XHG=1801 XHG=1867 XHG=1979 XHG=2141 XHG=2173 XHG=2218 XHG=2313 XHG=2379 YBD=1096 YBD=1087 YBD=1088 YBD=1089 YHG=1058>babies YHG=1068>were YHG=1058>found YHG=1059>dead YHG=1059>in YHG=1060>the YHG=1068>prone YHG=1059>position. YHG=1060>8 YHG=1059>of YHG=1059>these YHG=1059>had YHG=1060>their " XBD=260 XBD=372 XBD=509 XBD=554 XBD=687 XBD=796 XBD=904 XBD=941 XBD=1025 XBD=1112 XBD=1154 XBD=1195 XBD=1237 XHG=105 XHG=273 XHG=385 XHG=522 XHG=567 XHG=701 XHG=809 XHG=916 XHG=953 XHG=1037 XHG=1124 XHG=1165 XHG=1207 YBD=1108 YBD=1115 YBD=1107 YBD=1114 YBD=1113 YBD=1106 YBD=1106 YBD=1106 YBD=1111 YHG=1079>(artificial YHG=1079>infant YHG=1079>feeding YHG=1080>in YHG=1079>Shatin, YHG=1079>Hong YHG=1079>Kong YHG=1078>is YHG=1086>over YHG=1078>90% YHG=1084>at YHG=1078>2, YHG=1078>4, " XBD=1405 XBD=1549 XBD=1612 XBD=1765 XBD=1838 XBD=1887 XBD=1977 XBD=2090 XBD=2152 XBD=2236 XBD=2265 XBD=2371 XBD=2443 XHG=1340 XHG=1416 XHG=1559 XHG=1623 XHG=1776 XHG=1851 XHG=1897 XHG=1987 XHG=2099 XHG=2162 XHG=2247 XHG=2274 XHG=2380 YBD=1131 YBD=1138 YBD=1130 YBD=1132 YHG=1101>face Perhaps YHG=1102>towards YHG=1101>the YHG=1108>mattress YHG=1102>and YHG=1103>14 YHG=1112>were YHG=1103>facing YHG=1103>the YHG=1103>side; YHG=1103>8 YHG=1103>babies YHG=1113>were "" XBD=1086 XBD=171 XBD=204 XBD=369 XBD=448 XBD=667 XBD=806 XBD=939 XHG=109 XHG=186 XHG=220 XHG=387 XHG=462 XHG=682 XHG=821 XHG=953 YBD=1149 YBD=1158 YBD=1150 YBD=1157 YBD=1148 YBD=1148 YHG=1120>and YHG=1122>6 YHG=1121>months), YHG=1121>and YHG=1121>pathologists YHG=1121>beyond YHG=1120>carotid YHG=1112>bodies.3 XBD=1426 XBD=1472 XBD=1537 XBD=1655 XBD=1805 XBD=1879 XBD=1909 XBD=2003 XBD=2058 XBD=2150 XBD=2262 XHG=1341 XHG=1439 XHG=1483 XHG=1549 XHG=1668 XHG=1818 XHG=1893 XHG=1923 XHG=2016 XHG=2070 XHG=2162 YBD=1182 YBD=1173 YBD=1174 YBD=1175 YHG=1145>lying YHG=1145>in YHG=1146>the YHG=1145>lateral YHG=1145>position YHG=1146>and YHG=1146>5 YHG=1155>were YHG=1155>on YHG=1146>their YHG=1146>backs. " XBD=195 XBD=231 XBD=260 XBD=395 XBD=525 XBD=569 XBD=633 XBD=790 XBD=917 XBD=1035 XBD=1098 XBD=1238 XHG=108 XHG=207 XHG=244 XHG=272 XHG=408 XHG=537 XHG=581 XHG=646 XHG=801 XHG=929 XHG=1047 XHG=1110 YBD=1195 YBD=1194 YBD=1202 YBD=1192 YBD=1193 YBD=1192 YHG=1166>there YHG=1166>is YHG=1176>a YHG=1167>holistic YHG=1175>answer YHG=1173>to YHG=1165>the YHG=1165>question YHG=1164>&dquo;What YHG=1173>causes YHG=1170>cot YHG=1164>death?&dquo; " XBD=1537 XBD=1573 XBD=1612 XBD=1857 XBD=1935 XBD=2239 XBD=2445 XHG=1375 XHG=1551 XHG=1587 XHG=1626 XHG=1869 XHG=1948 XHG=2251 YBD=1225 YBD=1217 YBD=1226 YHG=1188>Although YHG=1188>it YHG=1189>is YHG=1188>disheartening YHG=1189>that YHG=1190>cardiorespiratory YHG=1190>physiologists " XBD=1241 XBD=212 XHG=860 XBD=293 XBD=365 XBD=499 XBD=553 XBD=671 XBD=728 XBD=761 XBD=842 XBD=986 XBD=1040 XBD=1193 XHG=108 XHG=229 XHG=311 XHG=383 XHG=514 XHG=571 XHG=687 XHG=745 XHG=777 XHG=1003YBD=1236 XHG=1051 XHG=1209 YBD=1239 YBD=1246 YBD=1238 YBD=1237 YBD=1245 YBD=1235 YBD=1235YHG=1206>volume YHG=1209>which YHG=1210>will YHG=1216>not YHG=1209>readily YHG=1210>be YHG=1209>found YHG=1209>by YHG=1217>a YHG=1214>vast YHG=1207>of YHG=1207>research YHG=1208>in

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Carpenter

XBD=2445 XBD=1412 XBD=1500 XBD=1600 XBD=1654 XBD=1712 XBD=1814 XBD=1964 XBD=2005 XBD=2066 XBD=2143 XBD=2263 XBD=2344 XBD=2399 XHG=1342 XHG=1422 XHG=1508 XHG=1609 XHG=1663 XHG=1722 XHG=1823 XHG=1972 XHG=2013 XHG=2075 XHG=2152 XHG=2272 XHG=2352 XHG=2406 YBD=1261 YBD=1269 YBD=1262 YBD=1271 YHG=1232>who YHG=1232>taken YHG=1241>up YHG=1239>cot YHG=1232>death YHG=1232>research YHG=1233>in YHG=1233>the YHG=1240>past YHG=1233>decade YHG=1233>have YHG=1240>not YHG=1242>yet XBD=240 XBD=426 XBD=628 XBD=671 XBD=808 XBD=900 XBD=946 XBD=1064 XBD=1144 XBD=1202 XBD=1248 XHG=110 XHG=247 XHG=435 XHG=637 XHG=680 XHG=816 XHG=909 XHG=949 XHG=1072 XHG=1152 XHG=1211 YBD=1283 YBD=1290 YBD=1281 YBD=1280 YBD=1287 YBD=1279 YBD=1279 YBD=1281 YBD=1280 YHG=1253>isolated YHG=1254>disciplines YHG=1252>of YHG=1261>or YHG=1251>isolated YHG=1257>parts YHG=1250>of YHG=1250>infants YHG=1250>who YHG=1251>die YHG=1250>of medicine XBD=1443 XBD=1559 XBD=1618 XBD=1710 XBD=1771 XBD=1902 XBD=1927 XBD=2063 XBD=2140 XBD=2325 XBD=2446 XHG=1343 XHG=1453 XHG=1570 XHG=1629 XHG=1721 XHG=1783 XHG=1915 XHG=1939 XHG=2074 XHG=2152 XHG=2335 YBD=1305 YBD=1310 YBD=1304 YBD=1313 YBD=1306 YBD=1307 YHG=1276>found YHG=1286>causes YHG=1276>for YHG=1283>most YHG=1283>cot YHG=1276>deaths, YHG=1276>I YHG=1283>suspect YHG=1277>that YHG=1277>Davies YHG=1277>clouded has XBD=160 XHG=885 XBD=276 XBD=305 XBD=396 XBD=456 XBD=601 XBD=693 XBD=773 XBD=836 XBD=871 XBD=957 XBD=1035 XBD=1099 XBD=1205 XBD=1243 XHG=110 XHG=174 XHG=292 XHG=319 XHG=410 XHG=470 XHG=614 XHG=704 XHG=785 XHG=851 XHG=970YBD=1332 XHG=1049 XHG=1113 XHG=1218 YBD=1326 YBD=1325 YBD=1324 YBD=1323 YBD=1329 YBD=1331 YBD=1324 YBD=1323 YBD=1324 YHG=1304>cot YHG=1297>death. YHG=1298>I YHG=1297>echo YHG=1297>Dr YHG=1295>Odent’s YHG=1295>view YHG=1295>(Jan YHG=1295>25, YHG=1304>p YHG=1295>214) YHG=1294>that YHG=1301>cot YHG=1295>death YHG=1295>is XBD=1459 XBD=1574 XBD=1694 XBD=1787 XBD=1956 XBD=2042 XBD=2200 XBD=2268 XBD=2335 XBD=2446 XHG=1343 XHG=1476 XHG=1592 XHG=1711 XHG=1805 XHG=1973 XHG=2059 XHG=2220 XHG=2284 XHG=2351 YBD=1349 YBD=1357 YBD=1348 YBD=1350 YBD=1358 YHG=1321>several YHG=1321>issues YHG=1320>rather YHG=1320>than YHG=1320>provided YHG=1330>new YHG=1321>insights. YHG=1320>He YHG=1321>has YHG=1322>merely XBD=226 XBD=263 XBD=399 XBD=457 XBD=613 XBD=710 XBD=846 XBD=951 XBD=1091 XBD=1244 XHG=111 XHG=246 XHG=283 XHG=420 XHG=472 XHG=633 XHG=730 XHG=866 XHG=971 XHG=1111 YBD=1378 YBD=1369 YBD=1370 YBD=1368 YBD=1367 YBD=1375 YBD=1367 YHG=1341>largely YHG=1350>a YHG=1341>disease YHG=1340>of YHG=1339>societies YHG=1338>with YHG=1338>certain YHG=1338>child YHG=1339>rearing YHG=1338>cultural XBD=1506 XBD=1569 XBD=1648 XBD=1724 XBD=1902 XBD=2073 XBD=2118 XBD=2310 XBD=2447 XHG=1343 XHG=1515 XHG=1580 XHG=1658 XHG=1736 XHG=1914 XHG=2083 XHG=2129 XHG=2320 YBD=1393 YBD=1401 YBD=1392 YBD=1400 YHG=1364>reiterated YHG=1364>the YHG=1364>idea YHG=1364>that YHG=1364>particular YHG=1363>life-styles YHG=1373>or YHG=1364>care-taking YHG=1365>practices XBD=272 XHG=904 XBD=346 XBD=409 XBD=639 XBD=706 XBD=828 XBD=893 XBD=986 XBD=1031 XBD=1146 XBD=1244 XHG=112 XHG=285 XHG=356 XHG=421 XHG=651 XHG=717 XHG=839 XHG=999YBD=1419 XHG=1041 XHG=1157 YBD=1421 YBD=1412 YBD=1411 YBD=1410 YBD=1411 YBD=1412 YBD=1413 YHG=1385>practices, YHG=1384>and YHG=1383>the YHG=1382>pathogenesis YHG=1382>lies YHG=1382>within YHG=1382>the YHG=1392>ways YHG=1383>in YHG=1382>which YHG=1383>these

" XBD=2060 XBD=1393 XBD=1576 XBD=1763 XBD=1817 XHG=1344 XHG=1406 XHG=1589 XHG=1775 XHG=1830 XHG=1943 YBD=1444 YBD=1437 YBD=1436 YHG=1417>are YHG=1408>important YHG=1407>influences YHG=1417>on YHG=1407>infant YHG=1407>deaths. " XBD=1930 XBD=217 XHG=845 XBD=291 XBD=383 XBD=527 XBD=641 XBD=733 XBD=830 XBD=874 XBD=984 XBD=1067 XBD=1146 XBD=1245 XHG=886 XHG=111 XHG=230 XHG=304 XHG=396 XHG=540 XHG=652 XHG=746 XHG=996YBD=1455 XHG=1080 XHG=1158 YBD=1457 YBD=1456 YBD=1462 YBD=1454 YBD=1455 YBD=1455 YHG=1428>babies YHG=1428>and YHG=1427>their YHG=1425>families YHG=1425>spend YHG=1425>their YHG=1425>lives. YHG=1425>A YHG=1425>closer YHG=1426>look YHG=1426>into YHG=1426>these " XBD=1243 XBD=245 XHG=786 XBD=441 XBD=530 XBD=581 XBD=675 XBD=775 XBD=886 XBD=1026 XBD=1137 XHG=112 XHG=257 XHG=454 XHG=542 XHG=593 XHG=688 XHG=898YBD=1498 XHG=1038 XHG=1149 YBD=1499 YBD=1505 YBD=1505 YBD=1499 YBD=1500 YHG=1471>cultural YHG=1470>differences YHG=1469>with YHG=1478>an YHG=1478>open YHG=1469>mind YHG=1469>might YHG=1470>provide YHG=1471>better YHG=1470>clues. Department of Paediatrics, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong

Department of Paediatrics, Leicester General Hospital, 1.

ROBERT Y. M. TSENG

1. Davies DP. Cot death in Hong Kong: a rare problem. Lancet 1985; ii: 1346-47. 2. O’Brien SJ, Matthews TG. Sheffield cot death risk score applied to an Irish population. Lancet 1985, i: 706. 3. Perrin DG, et al. Ultrastructure of carotid bodies in sudden infant death syndrome.

Pediatrics 1984; 73: 646-51.

|>" " XBD=557 XBD=634 XBD=784 XBD=858 XBD=930 XBD=1045 XBD=1158 XBD=1256 XBD=420 XHG=443 XHG=579 XHG=657 XHG=804 XHG=881 XHG=953 XHG=1068 XHG=1180 XHG=158 YBD=1987 YBD=1988 YBD=1988 YBD=1992 YBD=1988 YHG=1958>Davies YHG=1959>has YHG=1960>entered YHG=1959>the YHG=1966>cot YHG=1959>death YHG=1957>SIR,-Professor YHG=1968>arena YHG=1959>with

" XBD=515 XBD=312 XHG=407 XBD=393 XHG=124 YBD=2039 XHG=325 YBD=2038 YHG=2001>flying. YBD=2031 YHG=2001>speculative YHG=2002>fists " XBD=1263 XBD=213 XHG=921 XBD=350 XBD=413 XBD=545 XBD=684 XBD=746 XBD=822 XBD=882 XBD=912 XBD=994 XBD=1067 XBD=1128 XBD=1218 XHG=159 XHG=221 XHG=359 XHG=423 XHG=553 XHG=691 XHG=754 XHG=831 XHG=892 XHG=1001 XHG=1075 XHG=1136 XHG=1225 YBD=2073 YBD=2074 YBD=2082 YBD=2076 YBD=2080 YBD=2083 YBD=2075 YHG=2044>Mr YHG=2045>Nicholl YHG=2046>has YHG=2045>already YHG=2046>pointed YHG=2053>out YHG=2046>(Jan YHG=2046>25, YHG=2056>p YHG=2046>214) YHG=2047>that YHG=2046>the YHG=2046>basis YHG=2046>of XBD=179 XBD=291 XBD=401 XBD=465 XBD=573 XBD=744 XBD=860 XBD=1009 XBD=1140 XBD=1260 XHG=127 XHG=195 XHG=306 XHG=416 XHG=481 XHG=588 XHG=761 XHG=875 XHG=1025 XHG=1155 YBD=2125 YBD=2124 YBD=2117 YBD=2126 YBD=2119 YBD=2126 YHG=2090>the YHG=2089>Hong YHG=2088>Kong YHG=2094>cot YHG=2088>death YHG=2089>&dquo;survey&dquo; YHG=2099>seems YHG=2096>suspect. YHG=2089>Davies YHG=2089>points |>" " XBD=1691 XBD=1764 XBD=1947 XBD=2030 XBD=2092 XBD=2126 XBD=2209 XBD=2351 XBD=2406 XBD=2458 XBD=1541 XHG=1552 XHG=1702 XHG=1774 XHG=1957 XHG=2046 XHG=2105 XHG=2137 XHG=2220 XHG=2361 XHG=2414 XHG=1391 YBD=2125 YBD=2127 YBD=2124 YBD=2126 YBD=2118 YBD=2124 YHG=2089>Durrant YHG=2089>and YHG=2089>colleagues YHG=2089>(Oct YHG=2090>12, YHG=2099>p YHG=2090>842) YHG=2089>describe YHG=2089>the YHG=2099>use YHG=2090>SIR,-Dr XBD=180 XHG=902 XBD=260 XBD=291 XBD=439 XBD=642 XBD=682 XBD=789 XBD=833 XBD=887 XBD=917 XBD=1084 XBD=1170 XBD=1213 XBD=1259 XHG=126 XHG=194 XHG=275 XHG=305 XHG=453 XHG=657 XHG=696 XHG=801 XHG=847 XHG=931YBD=2163 XHG=1096 XHG=1184 XHG=1221 YBD=2169 YBD=2161 YBD=2162 YBD=2170 YBD=2161 YHG=2138>out YHG=2132>that YHG=2141>a YHG=2132>forensic YHG=2132>pathologist YHG=2133>is YHG=2133>asked YHG=2139>to YHG=2133>do YHG=2142>a YHG=2142>necropsy YHG=2133>only YHG=2132>if YHG=2142>an " XBD=2458 XBD=1394 XBD=1619 XBD=1720 XBD=1966 XBD=2040 XBD=2257 XHG=1357 XHG=1429 XHG=1659 XHG=1759 XHG=2007 XHG=2079 XHG=2295 YBD=2170 YBD=2162 YHG=2133>of YHG=2133>nafazatrom YHG=2133>and YHG=2133>prostacyclin YHG=2133>in YHG=2133>intractable YHG=2133>thrombotic XBD=225 XHG=850 XBD=328 XBD=391 XBD=481 XBD=632 XBD=672 XBD=698 XBD=840 XBD=987 XBD=1190 XBD=1260 XHG=126 XHG=235 XHG=337 XHG=401 XHG=490 XHG=640 XHG=681 XHG=705 XHG=996YBD=2213 XHG=1200 YBD=2204 YBD=2205 YBD=2206 YBD=2213 YHG=2175>infant YHG=2175>death YHG=2176>has YHG=2176>been YHG=2176>certified YHG=2176>in YHG=2185>a YHG=2177>hospital YHG=2177>casualty YHG=2176>department YHG=2176>and " XBD=2459 XBD=1668 XBD=1821 XBD=1952 XBD=2023 XBD=2114 XBD=2199 XBD=2227 XBD=2349 XHG=1357 XHG=1682 XHG=1832 XHG=1967 XHG=2037 XHG=2127 XHG=2212 XHG=2241 XHG=2362 YBD=2214 YBD=2205 YBD=2206 YBD=2213 YHG=2177>thrombocytopenic YHG=2186>purpura YHG=2177>(TTP). YHG=2177>We YHG=2177>have YHG=2186>seen YHG=2186>a YHG=2176>similar YHG=2177>patient " XBD=2458 XBD=143 XHG=917 XBD=250 XBD=305 XBD=408 XBD=537 XBD=591 XBD=710 XBD=902 XBD=966 XBD=1213 XBD=1260 XBD=1429 XBD=1623 XBD=1673 XBD=1809 XBD=1995 XBD=2100 XBD=2224 XBD=2353 XHG=127 XHG=159 XHG=267 XHG=315 XHG=424 XHG=553 XHG=608 XHG=729 XHG=983YBD=2249 XHG=1227 XHG=1357 XHG=1448 XHG=1641 XHG=1692 XHG=1829 XHG=2015 XHG=2118 XHG=2242 XHG=2368 YBD=2248 YBD=2255 YBD=2256 YBD=2257 YBD=2248 YBD=2257 YBD=2250 YBD=2249 YBD=2256 YHG=2228>a YHG=2228>cause YHG=2218>of YHG=2219>death YHG=2226>cannot YHG=2220>be YHG=2220>given. YHG=2219>Following YHG=2220>his YHG=2220>questionnaire YHG=2220>who YHG=2221>responded YHG=2227>to YHG=2220>exchange, YHG=2220>fresh YHG=2220>frozen YHG=2220>plasma YHG=2220>(FFP), XBD=250 XHG=684 XBD=491 XBD=585 XBD=663 XBD=898 XBD=1052 XBD=1260 XHG=127 XHG=270 XHG=511 XHG=603 XHG=919YBD=2293 XHG=1072 YBD=2300 YBD=2301 YBD=2292 YBD=2293 YBD=2300 YHG=2263>various YHG=2263>professionals YHG=2263>only YHG=2272>one YHG=2263>Government YHG=2263>forensic YHG=2263>pathologist " XBD=1880 XBD=1593 XBD=1669 XHG=1358 XHG=1608 XHG=1682 YBD=2302 YBD=2293 YHG=2264>dipyridamole, YHG=2264>and YHG=2264>nafazatrom. XBD=273 XHG=932 XBD=472 XBD=528 XBD=589 XBD=727 XBD=913 XBD=965 XBD=1059 XBD=1183 XBD=1262 XHG=128 XHG=290 XHG=490 XHG=540 XHG=608 XHG=747 XHG=982YBD=2336 XHG=1077 XHG=1202 YBD=2344 YBD=2341 YBD=2337 YBD=2344 YHG=2307>reported YHG=2308>experience YHG=2307>of YHG=2314>cot YHG=2307>deaths. YHG=2307>However, YHG=2308>in YHG=2307>both YHG=2307>public YHG=2308>and " XBD=2461 XBD=1421 XBD=1619 XBD=1750 XBD=1820 XBD=1844 XBD=1972 XBD=2018 XBD=2116 XBD=2145 XBD=2239 XBD=2411 XHG=1392 XHG=1428 XHG=1626 XHG=1758 XHG=1828 XHG=1853 XHG=1980 XHG=2021 XHG=2128 XHG=2154 XHG=2248 XHG=2418 YBD=2337 YBD=2346 YBD=2345 YBD=2336 YHG=2308>A YHG=2308>43-year-old YHG=2317>woman YHG=2308>had YHG=2318>a YHG=2308>relapse YHG=2308>of YHG=2308>TTP. YHG=2309>3 YHG=2317>years YHG=2308>previously YHG=2307>she XBD=247 XHG=756 XBD=400 XBD=557 XBD=613 XBD=733 XBD=861 XBD=1055 XBD=1262 XHG=128 XHG=270 XHG=423 XHG=580 XHG=637 XHG=885YBD=2387 XHG=1076 YBD=2388 YBD=2380 YBD=2379 YBD=2380 YHG=2351>private YHG=2351>medical YHG=2351>practice YHG=2351>in YHG=2351>Hong YHG=2351>Kong, YHG=2351>childhood YHG=2351>respiratory " XBD=2461 XBD=1420 XBD=1507 XBD=1716 XBD=1960 XBD=2165 XBD=2252 XHG=1358 XHG=1446 XHG=1533 XHG=1744 XHG=1989 XHG=2192 XHG=2277 YBD=2380 YBD=2386 YBD=2381 YBD=2388 YHG=2352>had YHG=2352>headaches, YHG=2351>paraesthesia, YHG=2352>confusion, YHG=2352>and YHG=2358>spontaneous XBD=295 XHG=912 XBD=360 XBD=448 XBD=618 XBD=684 XBD=897 XBD=959 XBD=1025 XBD=1113 XBD=1187 XBD=1261 XHG=129 XHG=311 XHG=374 XHG=461 XHG=635 XHG=699 XHG=973YBD=2423 XHG=1039 XHG=1126 XHG=1201 YBD=2424 YBD=2431 YBD=2423 YBD=2430 YHG=2394>infections YHG=2403>are YHG=2404>very YHG=2404>common. YHG=2394>An YHG=2394>explanation YHG=2394>for YHG=2394>the YHG=2403>very YHG=2394>low YHG=2401>cot" XBD=2462 XBD=1509 XBD=1598 XBD=1673 XBD=1755 XBD=2138 XBD=2224 XBD=2329 XBD=2404 XHG=1358 XHG=1532 XHG=1619 XHG=1693 XHG=1997 XHG=2158 XHG=2237 XHG=2350 XHG=2420 YBD=2432 YBD=2429 YBD=2424 YBD=2423 YHG=2395>bruising. YHG=2396>Her YHG=2396>Hb YHG=2404>was YHG=2396>platelets YHG=2396>24 YHG=2388>10911, YHG=2396>and YHG=2396>the x XBD=222 XHG=849 XBD=380 XBD=456 XBD=541 XBD=591 XBD=670 XBD=835 XBD=942 XBD=1040 XBD=1158 XBD=1221 XBD=1262 XHG=129 XHG=235 XHG=393 XHG=470 XHG=553 XHG=604 XHG=685 XHG=954YBD=2475 XHG=1052 XHG=1171 XHG=1234 YBD=2467 YBD=2469 YBD=2474 YBD=2467 YBD=2466 YHG=2438>death YHG=2439>reported YHG=2444>rate YHG=2447>may YHG=2439>be YHG=2438>that YHG=2438>although YHG=2447>many YHG=2447>more YHG=2438>babies YHG=2438>die YHG=2444>at " XBD=2463 XBD=1455 XBD=1550 XBD=1733 XBD=2056 XBD=2276 XBD=2329 XHG=1359 XHG=1481 XHG=1577 XHG=1760 XHG=2083 XHG=2303 XHG=2354 YBD=2468 YBD=2476 YBD=2467 YBD=2475 YHG=2439>blood YHG=2439>film YHG=2439>indicated YHG=2439>microangiopathic YHG=2439>haemolysis. YHG=2439>A YHG=2439>clotting XBD=233 XHG=843 XBD=267 XBD=400 XBD=577 XBD=663 XBD=716 XBD=830 XBD=876 XBD=1001 XBD=1068 XBD=1175 XBD=1233 XBD=1264 XHG=130 XHG=251 XHG=282 XHG=416 XHG=593 XHG=678 XHG=732 XHG=892YBD=2510 XHG=1014 XHG=1083 XHG=1188 XHG=1248 YBD=2515 YBD=2518 YBD=2517 YBD=2510 YBD=2517 YBD=2509 YHG=2482>home, YHG=2491>a YHG=2482>private YHG=2482>physician YHG=2490>may YHG=2482>be YHG=2481>called YHG=2489>to YHG=2481>certify YHG=2481>the YHG=2481>death YHG=2481>(as YHG=2490>a " XBD=2463 XBD=1467 XBD=1538 XBD=1630 XBD=1784 XBD=1873 XBD=2011 XBD=2109 XBD=2179 XBD=2351 XBD=2413 XHG=1361 XHG=1476 XHG=1546 XHG=1640 XHG=1792 XHG=1883 XHG=2023 XHG=2118 XHG=2189 XHG=2359 XHG=2421 YBD=2518 YBD=2511 YHG=2491>screen YHG=2482>renal YHG=2482>function YHG=2491>were YHG=2483>normal. YHG=2483>TTP YHG=2492>was YHG=2482>diagnosed YHG=2483>and YHG=2483>she XBD=318 XHG=850 XBD=493 XBD=567 XBD=620 XBD=836 XBD=983 XBD=1046 XBD=1214 XHG=131 XHG=330 XHG=506 XHG=579 XHG=634 XHG=996YBD=2554 XHG=1059 YBD=2562 YBD=2553 YBD=2561 YBD=2553 YHG=2526>respiratory YHG=2524>infection) YHG=2525>and YHG=2534>no YHG=2531>government YHG=2525>officials YHG=2534>are YHG=2525>involved. " XBD=2464 XBD=1422 XBD=1558 XBD=1652 XBD=1685 XBD=1912 XBD=2068 XBD=2189 XBD=2359 XBD=2438 XHG=1360 XHG=1441 XHG=1575 XHG=1669 XHG=1704 XHG=1929 XHG=2085 XHG=2207 XHG=2375 XHG=2452 YBD=2556 YBD=2555 YBD=2563 YBD=2554 YHG=2535>was YHG=2526>treated YHG=2526>with YHG=2525>prostacyclin YHG=2526>infusion YHG=2526>which YHG=2526>produced YHG=2526>only YHG=2535>a XBD=194 XHG=933 XBD=316 XBD=406 XBD=457 XBD=626 XBD=724 XBD=915 XBD=972 XBD=1101 XBD=1264 XHG=166 XHG=212 XHG=334 XHG=424 XHG=476 XHG=646 XHG=742 XHG=991YBD=2597 XHG=1120 YBD=2598 YBD=2605 YBD=2597 YBD=2597 YHG=2569>A YHG=2575>recent YHG=2569>visit YHG=2576>to YHG=2569>northern YHG=2568>Italy YHG=2568>illustrated YHG=2578>an YHG=2568>almost YHG=2568>identical " XBD=2464 XBD=1511 XBD=1584 XBD=1630 XBD=1794 XBD=1982 XBD=2118 XBD=2343 XBD=2404 XHG=1361 XHG=1525 XHG=1598 XHG=1644 XHG=1810 XHG=1996 XHG=2131 XHG=2356 XHG=2415 YBD=2606 YBD=2598 YHG=2570>transient YHG=2570>rise YHG=2570>in YHG=2569>platelets. YHG=2569>Following YHG=2569>clinical YHG=2570>deterioration YHG=2570>she YHG=2578>was " XBD=1266 XBD=281 XBD=393 XBD=620 XBD=836 XBD=921 XBD=1029 XBD=1079 XHG=133 XHG=291 XHG=406 XHG=632 XHG=931 XHG=1038 XHG=1089 YBD=2642 YBD=2641 YBD=2648 YBD=2649 YBD=2641 YBD=2648 YHG=2613>situation YHG=2613>where YHG=2612>Government YHG=2612>pathologists YHG=2612>only YHG=2612>rarely YHG=2612>do YHG=2612>necropsies XBD=1479XHG=847 XBD=1569 XBD=1790 XBD=1968 XBD=2068 XBD=2144 XBD=2366 XBD=2413 XBD=2465 XHG=1362 XHG=1491 XHG=1580 XHG=1802 XHG=1983 XHG=2082 XHG=2156 XHG=2379 XHG=2425 YBD=2642 YBD=2649 YHG=2614>treated YHG=2613>with YHG=2613>whole-blood YHG=2613>exchange, YHG=2613>FFP, YHG=2613>and YHG=2613>prednisolone YHG=2614>60 YHG=2622>mg XBD=175 XHG=841 XBD=239 XBD=348 XBD=468 XBD=613 XBD=825 XBD=866 XBD=1001 XBD=1214 XBD=1267 XHG=133 XHG=190 XHG=256 XHG=362 XHG=482 XHG=629 XHG=882YBD=2685 XHG=1016 XHG=1231 YBD=2684 YBD=2693 YBD=2691 YHG=2666>on YHG=2663>cot YHG=2656>death YHG=2656>babies YHG=2656>because YHG=2655>notification YHG=2655>is YHG=2656>grossly YHG=2655>incomplete. YHG=2655>In " XBD=2465 XBD=1454 XBD=1541 XBD=1729 XBD=1813 XBD=1913 XBD=1953 XBD=2062 XBD=2140 XBD=2286 XBD=2396 XHG=1362 XHG=1480 XHG=1566 XHG=1752 XHG=1836 XHG=1938 XHG=1977 XHG=2085 XHG=2164 XHG=2309 XHG=2416 YBD=2694 YBD=2693 YBD=2686 YBD=2685 YHG=2656>daily. YHG=2656>She YHG=2656>improved YHG=2657>and YHG=2657>after YHG=2667>a YHG=2657>week YHG=2657>her YHG=2656>platelet YHG=2664>count YHG=2666>was

2.

Templeman C. Two hundred and fifty-eight cases of suffocation of infants. Edinb Med J 1892; 38: 322-29. Martin RJ, Herrell N, Rubin D, Fanaroff A. Effect of supine and prone positions on arterial oxygen tension in the preterm infant. Pediatrics

XBD=348 XHG=789 XBD=546 XBD=655 XBD=746 XBD=774 XBD=867 XBD=1082 XBD=1182 XBD=1271 XHG=139 XHG=363 XHG=564 XHG=670 XHG=761 XHG=882YBD=2944 XHG=1096 XHG=1196 YBD=2954 YBD=2945 YBD=2945 YBD=2945 YHG=2917>&dquo;respiratory YHG=2916>infection&dquo;. YHG=2916>Since YHG=2917>then YHG=2916>I YHG=2916>have YHG=2916>interviewed YHG=2925>more YHG=2917>than XBD=2469 XBD=1449 XBD=1544 XBD=1628 XBD=1856 XBD=2032 XBD=2106 XBD=2251 XBD=2362 XBD=2428 XHG=1366 XHG=1469 XHG=1567 XHG=1649 XHG=1878 XHG=2054 XHG=2128 XHG=2272 XHG=2382 XHG=2446 YBD=2955 YBD=2954 YBD=2946 YBD=2947 YHG=2918>daily YHG=2918>FFP YHG=2918>and YHG=2917>prostacyclin YHG=2918>infusions YHG=2918>the YHG=2918>platelet YHG=2924>count YHG=2918>fell YHG=2926>to XBD=199 XHG=898 XBD=354 XBD=452 XBD=556 XBD=642 XBD=784 XBD=873 XBD=976 XBD=1102 XBD=1193 XBD=1272 XHG=142 XHG=226 XHG=380 XHG=478 XHG=582 XHG=669 XHG=811 XHG=1002 XHG=1127 XHG=1219 YBD=2996 YBD=2989 YBD=2988 YBD=2988 YHG=2961>100 YHG=2960>couples YHG=2961>who YHG=2960>have YHG=2960>lost YHG=2960>infants YHG=2959>and YHG=2959>have YHG=2959>found YHG=2960>that YHG=2959>the XBD=1435 XBD=1530 XBD=1620 XBD=1650 XBD=1756 XBD=1833 XBD=1907 XBD=2055 XBD=2114 XBD=2376 XBD=2415 XBD=2470 XHG=1371 XHG=1448 XHG=1547 XHG=1633 XHG=1662 XHG=1772 XHG=1845 XHG=1920 XHG=2067 XHG=2128 XHG=2387 XHG=2426 YBD=2989 YBD=2993 YBD=2997 YBD=2990 YBD=2991 YHG=2962>12 YHG=2954>109/1 YHG=2970>over YHG=2971>a YHG=2962>week. YHG=2961>She YHG=2971>was YHG=2961>referred YHG=2961>for YHG=2961>plasmapheresis YHG=2969>to YHG=2971>our x XBD=407 XHG=763 XBD=671 XBD=742 XBD=959 XBD=1055 XBD=1163 XBD=1272 XHG=140 XHG=427 XHG=692 XHG=979YBD=3039 XHG=1074 XHG=1184 YBD=3032 YBD=3031 YBD=3031 YHG=3003>epidemiological YHG=3003>characteristics YHG=3012>are YHG=3003>comparable YHG=3002>with YHG=3003>those YHG=3003>other XBD=1472 XBD=1554 XBD=1716 XBD=1797 XBD=1888 XBD=2026 XBD=2218 XBD=2298 XBD=2393 XBD=2471 XHG=1368 XHG=1493 XHG=1575 XHG=1736 XHG=1819 XHG=1909 XHG=2047 XHG=2239 XHG=2317 XHG=2411 YBD=3032 YBD=3040 YBD=3042 YBD=3033 YHG=3011>centre YHG=3005>received YHG=3011>two YHG=3004>litre YHG=3004>plasma YHG=3005>exchanges YHG=3005>and YHG=3005>daily YHG=3005>FFP XBD=223 XBD=339 XBD=402 XBD=523 XBD=586 XBD=773 XBD=940 XHG=140 XHG=236 XHG=352 XHG=416 XHG=537 XHG=599 YBD=3073 YBD=3074 YBD=3082 YBD=3081 YHG=3054>areas YHG=3046>where YHG=3053>cot YHG=3046>deaths YHG=3055>are YHG=3046>accurately YHG=3045>reported. XBD=1532XHG=785 XBD=1783 XBD=1855 XBD=1920 XBD=2017 XBD=2119 XBD=2212 XBD=2282 XBD=2407 XBD=2471 XHG=1368 XHG=1547 XHG=1798 XHG=1868 XHG=1931 XHG=2029 XHG=2131 XHG=2222 XHG=2293 XHG=2419 YBD=3084 YBD=3083 YBD=3075 YBD=3085 YBD=3076 YBD=3077 YHG=3047>infusions. YHG=3048>Dipyridamole YHG=3049>100 YHG=3056>mg YHG=3048>three YHG=3048>times YHG=3048>daily YHG=3057>was YHG=3049>started. YHG=3049>Her XBD=291 XHG=917 XBD=452 XBD=538 XBD=612 XBD=782 XBD=897 XBD=956 XBD=1019 XBD=1148 XBD=1201 XBD=1274 XHG=176 XHG=312 XHG=472 XHG=559 XHG=633 XHG=803 XHG=970YBD=3117 XHG=1040 XHG=1168 XHG=1221 YBD=3124 YBD=3125 YBD=3117 YBD=3117 YHG=3088>Davies YHG=3095>suggests YHG=3089>that YHG=3089>the YHG=3095>apparent YHG=3089>rarity YHG=3088>of YHG=3095>cot YHG=3088>deaths YHG=3088>in YHG=3088>the XBD=1494 XBD=1600 XBD=1688 XBD=1761 XBD=1825 XBD=2089 XBD=2240 XBD=2274 XBD=2386 XBD=2423 XBD=2472 XHG=1369 XHG=1504 XHG=1610 XHG=1700 XHG=1770 XHG=1835 XHG=2099 XHG=2250 XHG=2285 XHG=2395 XHG=2431 YBD=3125 YBD=3126 YBD=3120 YBD=3119 YHG=3090>platelet YHG=3097>count YHG=3099>rose, YHG=3091>and YHG=3091>her YHG=3090>haematological YHG=3099>progress YHG=3091>is YHG=3091>shown YHG=3092>in YHG=3092>the XBD=278 XHG=802 XBD=487 XBD=548 XBD=661 XBD=779 XBD=827 XBD=1019 XBD=1119 XBD=1193 XBD=1275 XHG=142 XHG=301 XHG=510 XHG=565 XHG=684 XHG=849YBD=3160 XHG=1041 XHG=1140 XHG=1215 YBD=3167 YBD=3159 YBD=3168 YBD=3160 YBD=3160 YBD=3159 YHG=3131>Chinese YHG=3131>population YHG=3131>of YHG=3131>Hong YHG=3131>Kong YHG=3132>is YHG=3132>consistent YHG=3132>with YHG=3131>the YHG=3131>low XBD=1479 XBD=1532 XBD=1597 XBD=1677 XBD=1819 XBD=1863 XBD=2036 XBD=2130 XBD=2214 XBD=2279 XBD=2420 XBD=2472 XHG=1369 XHG=1492 XHG=1544 XHG=1609 XHG=1689 XHG=1831 XHG=1874 XHG=2048 XHG=2141 XHG=2227 XHG=2291 XHG=2428 YBD=3169 YBD=3161 YBD=3162 YBD=3170 YBD=3163 YHG=3133>figure. YHG=3134>At YHG=3133>the YHG=3133>first YHG=3140>attempt YHG=3140>to YHG=3133>withdraw YHG=3133>daily YHG=3133>FFP YHG=3133>she YHG=3134>relapsed YHG=3135>but XBD=287 XHG=770 XBD=375 XBD=417 XBD=579 XBD=650 XBD=762 XBD=935 XBD=1064 XBD=1112 XBD=1275 XHG=143 XHG=296 XHG=384 XHG=426 XHG=588 XHG=657 XHG=944YBD=3203 XHG=1076 XHG=1121 YBD=3210 YBD=3202 YBD=3211 YBD=3203 YBD=3202 YBD=3203 YHG=3174>reported YHG=3180>rates YHG=3174>in YHG=3174>Malaysia YHG=3175>and YHG=3175>North YHG=3174>American YHG=3174>Asians. YHG=3174>In YHG=3174>Leicester XBD=1533 XBD=1629 XBD=1770 XBD=1944 XBD=2221 XBD=2300 XBD=2395 XBD=2473 XHG=1370 XHG=1552 XHG=1650 XHG=1791 XHG=1965 XHG=2241 XHG=2320 XHG=2413 YBD=3212 YBD=3213 YBD=3206 YBD=3214 YBD=3205 YHG=3176>improved YHG=3177>with YHG=3176>further YHG=3176>intensive YHG=3176>plasmapheresis YHG=3177>and YHG=3177>daily YHG=3177>FFP XBD=215 XHG=907 XBD=286 XBD=371 XBD=441 XBD=547 XBD=678 XBD=798 XBD=889 XBD=920 XBD=1015 XBD=1111 XBD=1277 XHG=143 XHG=232 XHG=303 XHG=391 XHG=459 XHG=565 XHG=694 XHG=814 XHG=937YBD=3246 XHG=1031 XHG=1128 YBD=3253 YBD=3245 YBD=3254 YBD=3247 YHG=3227>over YHG=3217>the YHG=3224>past YHG=3217>5V2 YHG=3226>years YHG=3217>during YHG=3218>which YHG=3218>time YHG=3218>I YHG=3218>have YHG=3219>been YHG=3217>officially XBD=1578 XBD=1652 XBD=1690 XBD=1762 XBD=1856 XBD=1982 XBD=2097 XBD=2295 XBD=2361 XBD=2416 XBD=2473 XHG=1371 XHG=1590 XHG=1661 XHG=1700 XHG=1774 XHG=1867 XHG=1991 XHG=2108 XHG=2303 XHG=2371 XHG=2425 YBD=3248 YBD=3256 YBD=3255 YBD=3257 YBD=3249 YHG=3220>replacement YHG=3221>and YHG=3226>at YHG=3220>this YHG=3226>stage YHG=3220>started YHG=3219>taking YHG=3219>nafazatrom YHG=3221>400 YHG=3230>mg YHG=3221>five XBD=277 XBD=331 XBD=399 XBD=544 XBD=598 XBD=648 XBD=784 XBD=900 XBD=1024 XBD=1073 XBD=1141 XBD=1230 XBD=1283 XHG=144 XHG=290 XHG=345 XHG=415 XHG=560 XHG=608 XHG=664 XHG=917 XHG=1041 XHG=1088 XHG=1157 XHG=1244 YBD=3297 YBD=3288 YBD=3289 YBD=3290 YBD=3290 YBD=3298 YBD=3290 YHG=3260>notified YHG=3261>by YHG=3260>the YHG=3270>coroner YHG=3260>of YHG=3261>all YHG=3261>sudden YHG=3261>infant YHG=3262>deaths YHG=3262>in YHG=3262>the YHG=3261>City YHG=3260>of XBD=1461XHG=800 XBD=1565 XHG=1371 XHG=1475 YBD=3292 YBD=3300 YHG=3262>times YHG=3263>daily. XBD=309 XHG=750 XBD=341 XBD=448 XBD=566 XBD=655 XBD=739 XBD=917 XBD=1004 XBD=1053 XBD=1175 XBD=1248 XBD=1276 XHG=145 XHG=323 XHG=353 XHG=459 XHG=577 XHG=667 XHG=927YBD=3339 XHG=1014 XHG=1066 XHG=1187 XHG=1258 YBD=3337 YBD=3331 YBD=3332 YBD=3333 YBD=3332 YBD=3331 YHG=3304>Leicester, YHG=3304>6 YHG=3302>Asian YHG=3303>babies YHG=3304>have YHG=3304>died YHG=3304>compared YHG=3304>with YHG=3305>49 YHG=3304>whites YHG=3304>and YHG=3305>7 XBD=1607 XBD=1675 XBD=1743 XBD=1895 XBD=1969 XBD=2112 XBD=2319 XBD=2360 XBD=2420 XBD=2475 XHG=1405 XHG=1621 XHG=1688 XHG=1757 XHG=1909 XHG=1982 XHG=2127 XHG=2335 XHG=2373 XHG=2432 YBD=3342 YBD=3335 YBD=3334 YHG=3306>Nafazatrom YHG=3306>did YHG=3313>not YHG=3307>produce YHG=3315>any YHG=3306>obvious YHG=3306>side-effects. YHG=3307>It YHG=3307>did YHG=3314>not

" XBD=1116 XBD=1277 XBD=182 XBD=295 XBD=402 XBD=450 XBD=554 XBD=678 XBD=785 XBD=886 XBD=975 XBD=1064 XHG=145 XHG=191 XHG=307 XHG=416 XHG=464 XHG=567 XHG=695 XHG=799 XHG=990 XHG=1077 XHG=1123 YBD=3376 YBD=3382 YBD=3374 YBD=3375 YBD=3375 YBD=3375 YHG=3346>of YHG=3346>mixed YHG=3346>white YHG=3355>or YHG=3346>black YHG=3346>origin. YHG=3346>Since YHG=3355>more YHG=3347>than YHG=3348>30% YHG=3347>of YHG=3347>Leicester XBD=1501XHG=899 XBD=1528 XBD=1656 XBD=1719 XBD=1763 XBD=1900 XBD=2005 XBD=2048 XBD=2177 XBD=2339 XBD=2405 XBD=2475 XHG=2415 XHG=1372 XHG=1512 XHG=1540 XHG=1666 XHG=1730 XHG=1774 XHG=1910 XHG=2017 XHG=2060 XHG=2188 XHG=2351 YBD=3376 YBD=3385 YBD=3378 YBD=3377 YHG=3356>prevent YHG=3359>a YHG=3350>second YHG=3349>fall YHG=3349>in YHG=3349>platelet YHG=3356>count YHG=3358>as YHG=3349>plasma YHG=3349>exchange YHG=3350>and YHG=3349>FFP XBD=244 XBD=308 XBD=353 XBD=461 XBD=606 XBD=706 XBD=834 XBD=947 XBD=1045 XBD=1089 XBD=1233 XHG=144 XHG=258 XHG=321 XHG=366 XHG=474 XHG=619 XHG=719 XHG=961 XHG=1056 XHG=1102 XHG=1246 YBD=3417 YBD=3418 YBD=3426 YBD=3425 YBD=3419 YBD=3426 YBD=3418 YHG=3389>births YHG=3399>are YHG=3390>in YHG=3389>Asian YHG=3389>families YHG=3390>these YHG=3389>figures YHG=3390>might YHG=3399>seem YHG=3396>support YHG=3397>to " XBD=1278 XBD=1452XHG=848 XBD=1566 XBD=1780 XBD=1858 XBD=1931 XBD=2069 XBD=2144 XBD=2286 XBD=2321 XBD=2476 XHG=1371 XHG=1472 XHG=1586 XHG=1802 XHG=1878 XHG=1952 XHG=2090 XHG=2163 XHG=2306 XHG=2340 YBD=3428 YBD=3419 YBD=3427 YBD=3420 YBD=3421 YHG=3401>were YHG=3393>being YHG=3392>withdrawn, YHG=3393>but YHG=3392>the YHG=3392>patient YHG=3392>did YHG=3392>achieve YHG=3402>a YHG=3392>sustained

1979; 63: 528-31

3. Orenstein SR,

Whitington PF, Orenstein DM. The infant seat as treatment for gastroesophageal reflux. N Engl J Med 1983; 309: 760-63. 4. Carpenter RG, Shaddick CW. Role of infection, suffocation and bottle feeding m cot death: an analysis of some factors in the histories of 110 cases and their controls. Br J Prev Soc Med 1965; 19: 1-7. 5. Emery JL. Epidemiology of sudden unexpected or rapid deaths in children. Br Med J 1959; ii: 925-28.

NAFAZATROM IN THROMBOCYTOPENIC PURPURA

" XBD=1561 XBD=215 XHG=616 XBD=336 XBD=378 XBD=528 XBD=587 XBD=855 XBD=1000 XBD=1267 XBD=1452 XHG=138 XHG=244 XHG=366 XHG=408 XHG=555 XHG=884YBD=2728 XHG=1027 XHG=1363 XHG=1465 YBD=2729 YBD=2728 YBD=2728 YBD=2729 YHG=2701>1979 YHG=2700>when YHG=2700>I YHG=2700>arrived YHG=2699>in YHG=2699>Leicestershire YHG=2699>similar YHG=2699>circumstances YHG=2701>239x YHG=2693>109/1. XBD=1461 XBD=1632 XBD=1713 XBD=1768 XBD=1822 XBD=1999 XBD=2088 XBD=2117 XBD=2248 XBD=2378 XHG=1399 XHG=1474 XHG=1643 XHG=1727 XHG=1780 XHG=1835 XHG=2011 XHG=2100 XHG=2130 XHG=2260 XHG=2389 YBD=2771 YBD=2772 YBD=2780 YBD=2773 YHG=2744>She YHG=2744>remained YHG=2743>well YHG=2752>on YHG=2752>no YHG=2750>treatment YHG=2744>with YHG=2753>a YHG=2744>normal YHG=2744>platelet YHG=2751>count " XBD=2467 XBD=301 XHG=864 XBD=552 XBD=644 XBD=709 XBD=854 XBD=902 XBD=1027 XBD=1138 XBD=1267 XHG=135 XHG=315 XHG=563 XHG=655 XHG=721 XHG=907YBD=2771 XHG=1038 XHG=1148 YBD=2781 YBD=2772 YBD=2771 YBD=2776 YHG=2743>prevailed. YHG=2743>Paediatricians YHG=2751>were YHG=2749>not YHG=2742>notified YHG=2742>of YHG=2742>sudden YHG=2742>infant YHG=2742>deaths, XBD=197 XHG=790 XBD=222 XBD=296 XBD=375 XBD=428 XBD=456 XBD=570 XBD=778 XBD=952 XBD=1029 XBD=1091 XBD=1196 XBD=1268 XHG=136 XHG=209 XHG=234 XHG=308 XHG=386 XHG=439 XHG=468 XHG=582 XHG=964YBD=2822 XHG=1041 XHG=1104 XHG=1207 YBD=2814 YBD=2823 YBD=2815 YBD=2816 YBD=2814 YBD=2815 YHG=2787>and YHG=2786>I YHG=2796>was YHG=2787>told YHG=2787>by YHG=2796>a YHG=2786>senior YHG=2786>community YHG=2786>physician YHG=2786>that YHG=2792>cot YHG=2786>death YHG=2795>was " XBD=2468 XBD=1445 XBD=1622 XBD=1746 XBD=1870 XBD=1948 XBD=2128 XBD=2329 XBD=2414 XHG=1363 XHG=1476 XHG=1658 XHG=1777 XHG=1900 XHG=1976 XHG=2159 XHG=2359 XHG=2438 YBD=2824 YBD=2823 YBD=2821 YBD=2816 YBD=2817 YHG=2788>until YHG=2788>October, YHG=2787>1985, YHG=2782>when YHG=2787>leg YHG=2788>bruising, YHG=2787>confusion, YHG=2789>and YHG=2797>an " XBD=203 XBD=245 XBD=315 XBD=453 XBD=516 XBD=645 XBD=780 XBD=810 XBD=882 XBD=977 XBD=1066 XBD=1140 XBD=1269 XHG=136 XHG=212 XHG=253 XHG=324 XHG=465 XHG=525 XHG=655 XHG=788 XHG=820 XHG=892 XHG=986 XHG=1074 XHG=1149 YBD=2860 YBD=2858 YBD=2859 YBD=2866 YBD=2857 YBD=2865 YBD=2857 YBD=2858 YHG=2840>rare YHG=2830>in YHG=2830>this YHG=2830>district. YHG=2829>On YHG=2829>further YHG=2829>inquiry YHG=2829>it YHG=2838>was YHG=2829>quite YHG=2829>clear YHG=2829>that YHG=2830>sudden |>"XBD=2465 XBD=1540 XBD=1716 XBD=1906 XBD=1985 XBD=2121 XBD=2225 XBD=2294 XBD=2361 XBD=2386 XBD=2465 XHG=1365 XHG=1551 XHG=1727 XHG=1920 XHG=1997 XHG=2131 XHG=2235 XHG=2308 XHG=2368 XHG=2398 XHG=2457 YBD=2868 YBD=2867 YBD=2859 YBD=2855 YBD=2860 YBD=2860 YHG=2831>expressive YHG=2830>dysphasia YHG=2830>developed. YHG=2831>Her YHG=2831>platelet YHG=2838>count YHG=2840>was YHG=2832>166 YHG=2836>x YHG=2825>109/1 YHG=2833>1 XBD=237 XHG=720 XBD=357 XBD=449 XBD=555 XBD=709 XBD=752 XBD=1081 XBD=1223 XBD=1270 XHG=137 XHG=250 XHG=370 XHG=461 XHG=567 XHG=765YBD=2901 XHG=1092 XHG=1236 YBD=2904 YBD=2903 YBD=2909 YBD=2902 YBD=2909 YBD=2901 YBD=2902 YHG=2873>infant YHG=2874>deaths YHG=2882>were YHG=2873>being YHG=2873>certified YHG=2882>as YHG=2872>&dquo;cardiorespiratory YHG=2872>failure&dquo; YHG=2882>or " XBD=2469 XBD=1428 XBD=1565 XBD=1820 XBD=1894 XBD=2032 XBD=2086 XBD=2153 XBD=2259 XBD=2345 XHG=1366 XHG=1441 XHG=1579 XHG=1832 XHG=1908 XHG=2046 XHG=2100 XHG=2165 XHG=2271 XHG=2360 YBD=2910 YBD=2904 YBD=2903 YBD=2911 YHG=2875>and YHG=2875>red-cell YHG=2874>fragmentation YHG=2884>was YHG=2881>present YHG=2884>on YHG=2874>the YHG=2874>blood YHG=2875>film. YHG=2875>Despite

" " " " " " " " " "

PETER G. F. SWIFT

Leicester LE5 4PW

9-9x10/1,

" " " " "

499

XBD=2420 XBD=1380 XBD=1641 XBD=1692 XBD=1859 XBD=1914 XBD=2080 XBD=2279 XBD=1371 XBD=1518 XBD=1594 XBD=1681 XBD=1725 XBD=1790 XBD=1899 XBD=2027 XBD=2096 XBD=2148 XBD=2300 XBD=2346 XBD=2422 XBD=1497 XBD=1591 XBD=1673 XBD=1845 XBD=1937 XBD=1984 XBD=2103 XBD=2143 XBD=2236 XBD=2299 XBD=2334 XBD=2374 XBD=2420 XBD=1476 XBD=1558 XBD=1609 XBD=1798 XBD=1897 XBD=2020 XBD=2125 XBD=2276 XBD=2419 XBD=1409 XBD=1586 XBD=1675 XBD=1819 XBD=1871 XBD=1911 XBD=2003 XBD=2161 XBD=2200 XBD=2286 XBD=2375 XBD=2419

XHG=2296 XHG=1291 XHG=1398 XHG=1658 XHG=1709 XHG=1876 XHG=1931 XHG=2098 XHG=1291 XHG=1387 XHG=1534 XHG=1609 XHG=1697 XHG=1742 XHG=1809 XHG=1914 XHG=2042 XHG=2112 XHG=2165 XHG=2315 XHG=2361 XHG=1290 XHG=1506 XHG=1602 XHG=1681 XHG=1855 XHG=1946 XHG=1994 XHG=2112 XHG=2152 XHG=2246 XHG=2309 XHG=2343 XHG=2382 XHG=1291 XHG=1497 XHG=1577 XHG=1629 XHG=1818 XHG=1918 XHG=2039 XHG=2144 XHG=2296 XHG=1291 XHG=1423 XHG=1601 XHG=1688 XHG=1834 XHG=1878 XHG=1926 XHG=2016 XHG=2176 XHG=2213 XHG=2299 XHG=2387

YBD=320 YBD=321 YBD=313 YBD=312 YBD=319 YBD=358 YBD=357 YBD=363 YBD=356 YBD=365 YBD=410 YBD=402 YBD=400 YBD=401 YBD=453 YBD=451 YBD=446 YBD=454 YBD=445 YBD=496 YBD=490 YBD=498 YBD=489

YHG=285>platelet YHG=285>remit YHG=285>spontaneously YHG=293>or YHG=284>maintain YHG=293>an YHG=284>adequate YHG=283>circulating YHG=338>mass YHG=328>without YHG=329>help YHG=335>at YHG=328>all. YHG=328>They YHG=327>should YHG=334>not YHG=327>be YHG=327>exposed YHG=334>to YHG=338>any YHG=382>unnecessary YHG=373>risks. YHG=373>Any YHG=380>treatment YHG=379>must YHG=372>shown YHG=371>work YHG=371>if YHG=372>is YHG=379>to YHG=373>be it YHG=417>acceptable, YHG=417>and YHG=418>in YHG=417>childhood YHG=418>ITP, YHG=418>where YHG=426>more YHG=417>patients YHG=425>recover YHG=461>despite YHG=468>treatment YHG=462>than YHG=461>because YHG=462>of YHG=462>it, YHG=462>such YHG=462>evidence YHG=462>is YHG=470>very YHG=460>hard YHG=467>to

" XBD=1405 XHG=1290 YBD=535 YHG=505>obtain. Department of Haematology, Children’s Hospital,

J. S. LILLEYMAN

Sheffield S10 2TH

1.

Lilleyman JS. Management Haematol

2. Smith E. A

of childhood

idiopathic thrombocytopenic purpura Br J

1983; 54: 11-14.

practical treatise on disease in children London. Churchill,

1886. 247-52

IS LONE ATRIAL FIBRILLATION REALLY BENIGN?

" XBD=2422 XBD=1516 XHG=2357 XBD=1674 XBD=1853 XBD=1947 XBD=1996 XBD=2046 XBD=2122 XBD=2333 XHG=1329 YBD=1010 XHG=1535 XHG=1694 XHG=1871 XHG=1965 XHG=2014 XHG=2065 XHG=2140 YBD=1014 YHG=981>that YBD=1016 YBD=1017 YBD=1009 YBD=1008 YHG=979>SIR,-Your YHG=980>editorial YHG=980>challenge YHG=979>(Feb YHG=980>8) YHG=987>to YHG=989>our YHG=974>conclusion " XBD=2423 XBD=1479 XHG=2407 XBD=1565 XBD=1669 XBD=1867 XBD=2012 XBD=2061 XBD=2114 XBD=2300 XBD=2391 XHG=1293 YBD=1053 XHG=1495 XHG=1582 XHG=1685 XHG=1884 XHG=2029 XHG=2077 XHG=2131 XHG=2315 YBD=1060 YHG=1034>a YBD=1054 YHG=1024>established YHG=1025>lone YHG=1024>atrial YHG=1024>fibrillation YHG=1033>appears YHG=1032>to YHG=1025>be YHG=1025>associated YHG=1025>with reference

" XBD=2422 XBD=1407 XHG=2390 XBD=1582 XBD=1619 XBD=1725 XBD=1777 XBD=1870 XBD=2103 XBD=2208 XHG=1292 YBD=1097 XHG=1419 XHG=1594 XHG=1631 XHG=1736 XHG=1793 XHG=1883 XHG=2114 YBD=1105 YHG=1076>to YBD=1104 YBD=1102 YHG=1068>benign YHG=1069>prognosis YHG=1069>is YHG=1069>based YHG=1078>on YHG=1069>1985 YHG=1068>Framingham YHG=1061>data, " XBD=2421 XBD=1395 XHG=2345 XBD=1511 XBD=1590 XBD=1697 XBD=1748 XBD=1807 XBD=1860 XBD=2009 XBD=2145 XBD=2263 XBD=2331 XHG=1292 YBD=1142 XHG=1410 XHG=1525 XHG=1605 XHG=1710 XHG=1755 XHG=1821 XHG=1875 XHG=2023 XHG=2158 XHG=2276 YBD=1150 YHG=1113>have YBD=1141 YHG=1112>which YHG=1113>shows YHG=1113>that YHG=1122>many YHG=1112>of YHG=1113>the YHG=1113>43 YHG=1113>patients YHG=1113>studied YHG=1113>would YHG=1119>not " XBD=2424 XBD=330 XHG=608 XBD=447 XBD=493 XBD=597 XBD=733 XHG=84 XHG=340 XHG=458 XHG=498 YBD=1191 YBD=1184 YBD=1185 YHG=1160>Haematological YHG=1167>course YHG=1167>a YHG=1160>of case TTP. XBD=1373 XBD=1568 XBD=1613 XBD=1741 XBD=1870 XBD=1972 XBD=2167 XBD=2221 XBD=2291 XHG=1294 XHG=1387 XHG=1581 XHG=1627 XHG=1755 XHG=1886 XHG=1986 XHG=2180 XHG=2235 XHG=2304 YBD=1184 YBD=1192 YBD=1185 YHG=1155>been YHG=1156>considered YHG=1165>as YHG=1156>having YHG=1155>&dquo;lone&dquo; YHG=1156>atrial YHG=1155>fibrillation YHG=1165>on YHG=1166>our YHG=1157>criteria " XBD=1435 XBD=1524 XBD=1577 XBD=1672 XBD=1748 XBD=1962 XBD=2244 XBD=2350 XBD=2425 XHG=1293 XHG=1453 XHG=1540 XHG=1585 XHG=1687 XHG=1762 XHG=1977 XHG=2259 XHG=2364 YBD=1228 YBD=1237 YBD=1229 YHG=1200>(because YHG=1201>12% YHG=1200>of YHG=1201>them YHG=1201>had YHG=1200>pre-existing YHG=1200>intraventricular YHG=1201>block YHG=1201>and " XBD=1191 XBD=413 XHG=760 XBD=728 XBD=929 XBD=1050 XHG=110 XHG=445 XHG=959YBD=1244 XHG=1081 YBD=1248 YBD=1250 YBD=1244 YBD=1252 YHG=1218>NFTM=nafazatrom; YHG=1218>DP=dipyridamole; YHG=1219>FFP=fresh YHG=1219>frozen YHG=1220>plasma; " XBD=1368 XBD=1441 XBD=1686 XBD=1948 XBD=2066 XBD=2149 XBD=2237 XBD=2328 XBD=2423 XHG=1294 XHG=1381 XHG=1452 XHG=1698 XHG=1964 XHG=2079 XHG=2160 XHG=2248 XHG=2339 YBD=1272 YBD=1281 YBD=1282 YBD=1273 YHG=1244>3107o YHG=1244>had YHG=1244>repolarisation YHG=1244>abnormalities). YHG=1245>There YHG=1254>may YHG=1245>have YHG=1244>been YHG=1254>more |>" XBD=148 XBD=354 XBD=492 XBD=681 XBD=850 XBD=850 XHG=84 XHG=158 XHG=365 XHG=504 XHG=692 XHG=831 YBD=1291 YBD=1288 YBD=1289 YBD=1290 YBD=1283 YHG=1258>PGI2 YHG=1258>= YHG=1258>infusion; YHG=1258>PE YHG=1252>exchange.2 YHG=1252>2 prostacyclin = plasma " XBD=2424 XBD=1364 XHG=2363 XBD=1483 XBD=1573 XBD=1665 XBD=1830 XBD=1884 XBD=1955 XBD=2089 XBD=2132 XBD=2224 XBD=2349 XHG=1293 YBD=1317 XHG=1378 XHG=1496 XHG=1586 XHG=1680 XHG=1843 XHG=1898 XHG=1969 XHG=2103 XHG=2139 XHG=2239 YBD=1316 YHG=1289>had YBD=1318 YBD=1326 YHG=1287>who YHG=1288>would YHG=1288>have YHG=1289>been YHG=1288>excluded YHG=1298>on YHG=1298>our YHG=1289>criteria YHG=1288>if YHG=1289>chest YHG=1288>X-rays " XBD=1983 XBD=1372 XHG=1764 XBD=1461 XBD=1505 XBD=1618 XBD=1751 XHG=1293 YBD=1369 XHG=1384 XHG=1473 XHG=1518 XHG=1632 YBD=1360 YHG=1333>enlargement. YBD=1361 YHG=1332>been YHG=1333>used YHG=1339>to YHG=1333>detect YHG=1333>cardiac

" XBD=2419 XBD=1392 XHG=2334 XBD=1603 XBD=1689 XBD=1801 XBD=1859 XBD=1930 XBD=2121 XBD=2213 XBD=2316 XHG=1326 YBD=1415 XHG=1411 XHG=1628 XHG=1707 XHG=1818 XHG=1878 XHG=1948 XHG=2140 XHG=2234 YBD=1408 YHG=1378>(7-5) YBD=1416 YBD=1407 YBD=1406 YHG=1378>Our YHG=1371>conclusion YHG=1389>was YHG=1379>based YHG=1388>on YHG=1379>the YHG=1379>follow-up, YHG=1388>over YHG=1378>1-19 " " " " " "" " " " " " " " " " "

XBD=2418 XBD=1386 XBD=1440 XBD=1487 XBD=1635 XBD=1725 XBD=1926 XBD=2026 XBD=2232 XBD=2373 XHG=1289 XHG=1402 XHG=1448 XHG=1503 XHG=1650 XHG=1740 XHG=1940 XHG=2040 XHG=2248 XHG=2387 YBD=1461 YBD=1460 YBD=1453 YBD=1452 YBD=1458 YBD=1451 YHG=1432>years, YHG=1423>of YHG=1424>83 YHG=1424>patients YHG=1424>with YHG=1423>established YHG=1423>atrial YHG=1423>fibrillation, YHG=1422>defined YHG=1432>as XBD=240 XBD=352 XBD=405 XBD=469 XBD=568 XBD=744 XBD=944 XBD=1043 XBD=1109 XBD=1199 XHG=90 XHG=251 XHG=365 XHG=416 XHG=481 XHG=582 XHG=756 XHG=955 XHG=1056 XHG=1120 YBD=1475 YBD=1474 YBD=1482 YBD=1483 YBD=1475 YBD=1475 YBD=1475 YBD=1476 YHG=1446>remission YHG=1445>whilst YHG=1455>on YHG=1445>the YHG=1447>drug. YHG=1446>Although YHG=1446>nafazatrom YHG=1446>alone YHG=1446>has YHG=1447>been XBD=1453 XBD=1514 XBD=1555 XBD=1642 XBD=1671 XBD=1778 XBD=1824 XBD=1889 XBD=2031 XBD=2177 XBD=2418 XHG=1289 XHG=1466 XHG=1527 XHG=1568 XHG=1656 XHG=1683 XHG=1792 XHG=1836 XHG=1901 XHG=2044 XHG=2188 YBD=1504 YBD=1502 YBD=1496 YBD=1497 YHG=1468>persistent YHG=1467>for YHG=1474>at YHG=1468>least YHG=1477>a YHG=1468>week, YHG=1468>in YHG=1468>the YHG=1468>absence YHG=1467>of YHG=1467>abnormalities ECG XBD=158 XBD=239 XBD=367 XBD=423 XBD=636 XBD=808 XBD=850 XBD=987 XBD=1114 XBD=1199 XHG=89 XHG=167 XHG=248 XHG=376 XHG=432 XHG=646 XHG=818 XHG=859 XHG=997 XHG=1123 YBD=1519 YBD=1527 YBD=1520 YBD=1518 YBD=1519 YBD=1527 YBD=1520 YHG=1490>used YHG=1490>with YHG=1499>success YHG=1490>for YHG=1490>maintaining YHG=1491>remission YHG=1490>in YHG=1490>another YHG=1491>patient YHG=1490>with XBD=1387 XBD=1499 XBD=1579 XBD=1820 XBD=1971 XBD=2210 XBD=2282 XBD=2417 XHG=1288 XHG=1417 XHG=1528 XHG=1610 XHG=1852 XHG=2002 XHG=2241 XHG=2312 YBD=1548 YBD=1541 YBD=1549 YHG=1512>(apart YHG=1512>from YHG=1512>the YHG=1512>arrhythmia), YHG=1512>cardiac YHG=1512>enlargement YHG=1521>on YHG=1511>X-ray, XBD=187 XBD=225 XBD=287 XBD=350 XBD=488 XBD=563 XBD=719 XBD=831 XBD=963 XBD=1128 XBD=1199 XHG=89 XHG=203 XHG=235 XHG=297 XHG=360 XHG=498 XHG=574 XHG=730 XHG=844 XHG=973 XHG=1139 YBD=1569 YBD=1571 YBD=1563 YBD=1564 YBD=1572 YBD=1564 YHG=1528>TTP, YHG=1535>it YHG=1534>did YHG=1541>not YHG=1541>prevent YHG=1535>that YHG=1534>patient’s YHG=1534>death. YHG=1535>Plasma YHG=1535>exchange YHG=1536>and XBD=1521 XBD=1586 XBD=1675 XBD=1857 XBD=2054 XBD=2202 XBD=2265 XBD=2419 XHG=1289 XHG=1552 XHG=1616 XHG=1703 XHG=1885 XHG=2084 XHG=2232 XHG=2294 YBD=1594 YBD=1586 YBD=1585 YBD=1593 YHG=1557>hypertension, YHG=1566>any YHG=1557>clinically YHG=1557>detectable YHG=1557>cardiac YHG=1566>or YHG=1556>thyroid XBD=156 XBD=379 XBD=451 XBD=527 XBD=631 XBD=824 XBD=958 XBD=1015 XBD=1198 XHG=89 XHG=179 XHG=402 XHG=475 XHG=551 XHG=655 XHG=847 XHG=982 XHG=1038 YBD=1608 YBD=1616 YBD=1608 YBD=1607 YBD=1615 YHG=1579>FFP YHG=1579>replacement YHG=1588>are YHG=1578>the YHG=1585>most YHG=1579>important YHG=1579>factors YHG=1579>in YHG=1579>achieving XBD=1494 XBD=1534 XBD=1597 XBD=1682 XBD=1732 XBD=1902 XBD=1971 XBD=2099 XBD=2132 XBD=2375 XBD=2417 XHG=1290 XHG=1505 XHG=1545 XHG=1609 XHG=1694 XHG=1737 XHG=1915 XHG=1982 XHG=2110 XHG=2144 XHG=2386 YBD=1629 YBD=1638 YBD=1630 YHG=1601>abnormality YHG=1608>at YHG=1601>the YHG=1601>time YHG=1601>of YHG=1601>diagnosis. YHG=1601>We YHG=1601>believe YHG=1601>it YHG=1601>inappropriate YHG=1608>to XBD=239 XBD=296 XBD=415 XBD=499 XBD=714 XBD=811 XBD=905 XBD=1007 XBD=1050 XBD=1140 XBD=1198 XHG=89 XHG=264 XHG=322 XHG=443 XHG=526 XHG=740 XHG=836 XHG=931 XHG=1034 XHG=1077 XHG=1166 YBD=1652 YBD=1651 YBD=1658 YBD=1661 YBD=1652 YBD=1652 YBD=1652 YHG=1623>remission YHG=1623>in YHG=1623>TTP, YHG=1624>but YHG=1622>nafazatrom YHG=1632>may YHG=1623>well YHG=1623>have YHG=1633>a YHG=1623>role YHG=1623>in XBD=1383 XBD=1463 XBD=1571 XBD=1716 XBD=1852 XBD=1897 XBD=2077 XBD=2212 XBD=2417 XHG=1289 XHG=1411 XHG=1493 XHG=1602 XHG=1747 XHG=1882 XHG=1927 XHG=2107 XHG=2240 YBD=1674 YBD=1682 YHG=1644>apply YHG=1646>the YHG=1645>label YHG=1645>&dquo;lone&dquo; YHG=1645>unless YHG=1655>a YHG=1645>stringent YHG=1646>search YHG=1645>(nowadays XBD=261 XBD=442 XHG=89 XHG=273 YBD=1704 YBD=1697 YHG=1668>supporting YHG=1667>remission. XBD=1450 XBD=1789 XBD=1869 XBD=1988 XBD=2045 XBD=2170 XBD=2256 XBD=2416 XHG=1289 XHG=1476 XHG=1815 XHG=1895 XHG=2013 XHG=2071 XHG=2197 XHG=2282 YBD=1726 YBD=1719 YBD=1727 YBD=1718 YHG=1689>including YHG=1690>echocardiography) YHG=1690>has YHG=1690>failed YHG=1697>to YHG=1690>reveal YHG=1699>any YHG=1689>relevant XBD=237 XBD=386 XBD=587 XBD=854 XBD=935 XBD=1012 XBD=1197 XHG=119 XHG=276 XHG=425 XHG=626 XHG=894 XHG=973 XHG=1052 YBD=1750 YBD=1741 YBD=1741 YBD=1742 YHG=1711>Platelet YHG=1718>counts YHG=1712>measured YHG=1712>automatically YHG=1721>on YHG=1721>an YHG=1712>ELT800 XBD=1458 XBD=1683 XHG=1289 XHG=1470 YBD=1764 YBD=1772 YHG=1734>associated YHG=1734>abnormality. XBD=261 XHG=948 XBD=337 XBD=458 XBD=525 XBD=630 XBD=713 XBD=786 XBD=938 XBD=989 XBD=1077 XBD=1198 XHG=88 XHG=272 XHG=349 XHG=471 XHG=535 XHG=640 XHG=726 XHG=797 XHG=1000 XHG=1088 YBD=1787 YBD=1787 YBD=1786 YBD=1794 YBD=1795 YBD=1794 YBD=1787 YHG=1758>instrument YHG=1757>that YHG=1763>counts YHG=1757>red YHG=1757>blood YHG=1757>cells YHG=1757>and YHG=1756>platelets YHG=1758>by YHG=1756>light YHG=1764>scatter Regional Cardiac Unit, XBD=142 XHG=845 XBD=363 XBD=457 XBD=505 XBD=641 XBD=711 XBD=790 XBD=836 XBD=952 XBD=1035 XBD=1156 XBD=1197 XHG=88 XHG=150 XHG=372 XHG=465 XHG=514 XHG=650 XHG=720 XHG=798 XHG=960 XHG=1044 XHG=1166 YBD=1831 YBD=1838 YBD=1832 YBD=1831 YBD=1839 YBD=1838 YBD=1837 YBD=1831 YHG=1802>and YHG=1802>distinguishes YHG=1802>them YHG=1802>by YHG=1802>particle YHG=1802>size YHG=1811>may YHG=1802>be YHG=1802>falsely YHG=1801>high YHG=1802>where, YHG=1811>as

" " " "

XBD=1197XHG=952 XBD=116 XBD=222 XBD=325 XBD=369 XBD=522 XBD=664 XBD=930 XBD=988 XBD=1063 XHG=88 XHG=133 XHG=242 XHG=344 XHG=387 XHG=540 XHG=683 XHG=1006 XHG=1080 YBD=1875 YBD=1881 YBD=1876 YBD=1875 YBD=1882 YBD=1874 YBD=1875 YBD=1883 YHG=1847>in YHG=1847>TTP, YHG=1846>there YHG=1846>is YHG=1846>unusual YHG=1846>red-cell YHG=1846>fragmentation. YHG=1847>In YHG=1856>our YHG=1847>patient XBD=252 XHG=771 XBD=324 XBD=458 XBD=582 XBD=674 XBD=759 XBD=916 XBD=1041 XBD=1196 XHG=88 XHG=263 XHG=335 XHG=471 XHG=594 XHG=686 XHG=929 XHG=1054 YBD=1920 YBD=1920 YBD=1928 YBD=1919 YBD=1927 YBD=1928 YHG=1891>automated YHG=1891>and YHG=1891>manual YHG=1897>counts YHG=1900>were YHG=1899>very YHG=1890>different YHG=1891>during YHG=1891>relapses, XBD=136 XHG=823 XBD=232 XBD=401 XBD=472 XBD=575 XBD=731 XBD=814 XBD=996 XBD=1065 XBD=1197 XHG=87 XHG=146 XHG=242 XHG=410 XHG=482 XHG=584 XHG=741 XHG=1004 XHG=1074 YBD=1964 YBD=1965 YBD=1971 YBD=1964 YBD=1972 YBD=1964 YHG=1936>but YHG=1935>when YHG=1935>remission YHG=1945>was YHG=1935>being YHG=1935>achieved YHG=1935>they YHG=1935>converged YHG=1935>and YHG=1935>red-cell XBD=242 XHG=830 XBD=333 XBD=386 XBD=505 XBD=591 XBD=645 XBD=710 XBD=818 XBD=906 XHG=87 YBD=2016 XHG=255 XHG=346 XHG=400 XHG=519 XHG=604 XHG=658 XHG=722 YBD=2015YHG=1979>fragments YBD=2009 YBD=2008 YHG=1989>were YHG=1988>no YHG=1979>longer YHG=1988>seen YHG=1989>on YHG=1979>the YHG=1979>blood YHG=1979>film.

Papworth Hospital, Papworth Everard, Cambridge CB3 8RE

1. Close JB, Evans DW, Bailey SM. Persistent lone atrial fibrillation- its prognosis after clinical diagnosis. J R Coll Gen Pract 1979; 29: 547-49. 2. Brand FN, Abbott RD, Kannel WB, Wolf PA. Characteristics and prognosis of lone atrial fibrillation. 30 year follow-up in the Framingham Study. JAMA 1985; 254: 3449-53.

" XBD=799 XBD=159 XHG=627 XBD=248 XBD=342 XBD=408 XBD=460 XBD=616 XHG=114 YBD=2072 XHG=169 XHG=259 XHG=353 XHG=419 XHG=471 YBD=2079 YHG=2047>nafazatrom. YHG=2048>We YHG=2047>thank YHG=2048>Bayer YHG=2047>UK YHG=2047>for YHG=2047>supplying

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J. A. COPPLESTONE Department ofHaematology, Royal Victoria Hospital, Bournemouth BH1 4JG

D. WAINWRIGHT EVANS S. M. BAILEY

ALISON WORSLEY S. SADULLAH T. J HAMBLIN

LIFE EXTENSION IN HEART DISEASE

XBD=2421 XHG=2356 XBD=1477 XBD=1577 XBD=1649 XBD=1816 XBD=1977 XBD=2062 XBD=2100 XBD=2131 XBD=2212 XBD=2348 XHG=1328 YBD=2318 XHG=1487 XHG=1588 XHG=1658 XHG=1825 XHG=1986 XHG=2075 XHG=2111 XHG=2140 XHG=2221 YBD=2322 YHG=2289>that YBD=2317 YBD=2323 YBD=2325 YHG=2287>SIR,-Dr YHG=2288>Tapp YHG=2289>and YHG=2288>Professor YHG=2288>Natelson YHG=2288>(Feb YHG=2289>1, YHG=2298>p YHG=2289>238) YHG=2289>showed 1. Williams HJH, KN. Thrombotic XBD=1575 XBD=1743 XBD=1920 XBD=1968 XBD=2127 XBD=2221 XBD=2297 XBD=2421 XHG=1293 XHG=1593 XHG=1761 XHG=1936 XHG=1985 XHG=2144 XHG=2239 XHG=2315 YBD=2369 YBD=2362 YBD=2370 YHG=2332>cardiomyopathic YHG=2333>hamsters YHG=2333>subjected YHG=2340>to YHG=2340>constant YHG=2333>light YHG=2333>live YHG=2334>longer Myatt L, Young thrombocytopenic purpura: treatment with nafazatrom. Clin Lab Haematol 1984; 6: 199-202. XBD=1367 XBD=1469 XBD=1643 XBD=1688 XBD=1718 XBD=1771 XBD=1806 XBD=1950 XHG=1292 YBD=2407 XHG=1381 XHG=1484 XHG=1656 XHG=1702 XHG=1736 XHG=1785 XHG=1820 YBD=2413 YHG=2387>are YBD=2405 YBD=2414 YHG=2377>than YHG=2377>those YHG=2377>subjected YHG=2384>to YHG=2387>a YHG=2378>12 YHG=2378>h YHG=2377>light/12 XBD=2073 XBD=2180 XBD=2358 XBD=2421 XHG=2000 XHG=2087 XHG=2197 XHG=2371 YBD=2406 YBD=2415 YBD=2408 YHG=2378>dark YHG=2378>cycle. YHG=2378>Hamsters XBD=1455 XHG=2333 XBD=1593 XBD=1735 XBD=1920 XBD=1962 XBD=2098 XBD=2259 XBD=2322 XBD=2419 XHG=1293 YBD=2459 XHG=1466 XHG=1608 XHG=1746 XHG=1930 XHG=1973 XHG=2108 XHG=2270 YBD=2451 YHG=2431>span. YBD=2450 YHG=2421>nocturnal YHG=2421>feeders. YHG=2421>Dietary YHG=2422>restriction YHG=2422>in YHG=2422>rodents YHG=2422>increases YHG=2422>life

h

" XBD=2418 XBD=1328 XHG=2279 XBD=1400 XBD=1513 XBD=1576 XBD=1738 XBD=1828 XBD=1891 XBD=1939 XBD=2073 XBD=2184 XBD=2268 XHG=1292 YBD=2505 XHG=1338 XHG=1412 XHG=1525 XHG=1587 XHG=1749 XHG=1839 XHG=1900 XHG=1948 XHG=2083 XHG=2193 YBD=2493 YHG=2466>pair-fed. YBD=2503 YBD=2494 YBD=2495 YHG=2466>In YHG=2465>this YHG=2466>study, YHG=2466>the YHG=2466>hamsters YHG=2475>were YHG=2465>fed YHG=2466>ad YHG=2466>libitum YHG=2466>rather YHG=2466>than

IMMUNE VINCRISTINE CHILDHOOD " XBD=2424 XBD=1397 XBD=1435 XBD=1490 XBD=1704 XBD=1759 XBD=1846 XBD=1971 XBD=2063 XBD=2118 XBD=2223 XBD=2349 XHG=1293 FOR XHG=1411 XHG=1448 XHG=1503 XHG=1717 XHG=1772 XHG=1859 XHG=1986 XHG=2077 XHG=2130 XHG=2237 XHG=2363 YBD=2539 YBD=2544 YBD=2538 YHG=2509>There YHG=2509>is YHG=2518>no YHG=2509>information YHG=2509>food YHG=2509>intake, YHG=2509>little YHG=2519>on YHG=2516>water YHG=2510>intake, YHG=2509>and

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THROMBOCYTOPENIA XBD=2424 XHG=2320 XBD=1375 XBD=1429 XBD=1525 XBD=1660 XBD=1768 XBD=1877 XBD=1948 XBD=2092 XBD=2154 XBD=2269 XBD=2306 XHG=1293 XHG=1388 XHG=1441 XHG=1537 XHG=1676 XHG=1781 XHG=1889 XHG=1961 XHG=2105 XHG=2167 XHG=2283 YBD=2591 YHG=2553>would YBD=2589 YBD=2590 YBD=2582 YBD=2583 YHG=2563>none YHG=2563>on YHG=2554>body YHG=2554>weight. YHG=2554>Some YHG=2553>tissue YHG=2561>wet YHG=2554>weights YHG=2563>are YHG=2555>given; YHG=2554>it XBD=1370 XBD=1477 XBD=1677 XBD=1739 XBD=1846 XBD=1966 XBD=2091 XBD=2176 XBD=2334 XBD=2424 XHG=1293 XHG=1398 XHG=1507 XHG=1707 XHG=1769 XHG=1875 XHG=1996 XHG=2120 XHG=2204 XHG=2363 YBD=2627 YBD=2635 YBD=2634 YBD=2626 YHG=2598>been YHG=2598>preferable YHG=2605>to YHG=2598>have YHG=2598>given YHG=2598>tissue YHG=2598>dry YHG=2598>weights YHG=2597>and XBD=254 XHG=883 XBD=459 XBD=547 XBD=587 XBD=621 XBD=706 XBD=871 XBD=921 XBD=1122 XBD=1194 XHG=113 XHG=265 XHG=471 XHG=558 XHG=601 XHG=634 XHG=718 XHG=937YBD=2642 XHG=1133 YBD=2649 YBD=2651 YBD=2643 YBD=2652 YBD=2652 YHG=2613>SIR,-Dr YHG=2614>Manoharan YHG=2614>(Feb YHG=2615>8, YHG=2624>p YHG=2614>317) YHG=2614>describes YHG=2623>an YHG=2614>11-year-old YHG=2615>boy XBD=1414 XBD=1582 XBD=1641 XBD=1747 XBD=1938 XBD=2059 XBD=2144 XBD=2286 XBD=2339 XBD=2419 XHG=1291 XHG=1440 XHG=1611 XHG=1668 XHG=1777 XHG=1965 XHG=2087 XHG=2173 XHG=2314 XHG=2365 YBD=2671 YBD=2679 YBD=2672 YHG=2643>protein YHG=2650>contents YHG=2652>as YHG=2643>well. YHG=2643>Increased YHG=2643>tissue YHG=2650>wet YHG=2643>weight YHG=2644>is YHG=2649>not XBD=150 XHG=758 XBD=302 XBD=629 XBD=740 XBD=830 XBD=1011 XBD=1105 XBD=1193 XHG=81 XHG=168 XHG=320 XHG=646 XHG=848 XHG=1029 XHG=1123 YBD=2687 YBD=2695 YBD=2696 YBD=2687 YBD=2687 YBD=2687 YHG=2658>with YHG=2658>immune YHG=2658>thrombocytopenia YHG=2658>(ITP) YHG=2658>who YHG=2658>recovered YHG=2657>after YHG=2658>four XBD=1475 XBD=1660 XBD=1719 XBD=1924 XBD=2057 XBD=2255 XBD=2367 XBD=2419 XHG=1292 XHG=1495 XHG=1681 XHG=1733 XHG=1947 XHG=2078 XHG=2276 XHG=2387 YBD=2724 YBD=2723 YBD=2716 YHG=2687>necessarily YHG=2687>indicative YHG=2686>of YHG=2688>congestion. YHG=2687>Before YHG=2687>physicians YHG=2687>begin YHG=2694>to XBD=225 XHG=789 XBD=281 XBD=482 XBD=553 XBD=649 XBD=718 XBD=769 XBD=974 XBD=1045 XBD=1144 XBD=1193 XHG=81 XHG=245 XHG=294 XHG=504 XHG=574 XHG=669 XHG=738 XHG=992 XHG=1064 XHG=1161 YBD=2731 YBD=2732 YBD=2731 YBD=2739 YBD=2731 YBD=2731 YHG=2701>infusions YHG=2702>of YHG=2702>vincristine. YHG=2702>He YHG=2703>cites YHG=2712>me YHG=2712>as YHG=2703>supporting YHG=2702>the YHG=2703>need YHG=2709>to XBD=1403XHG=777 XBD=1493 XBD=1637 XBD=1723 XBD=1817 XBD=1938 XBD=1979 XBD=2131 XBD=2219 XBD=2275 XBD=2419 XHG=1291 XHG=1414 XHG=1503 XHG=1647 XHG=1732 XHG=1829 XHG=1948 XHG=1990 XHG=2142 XHG=2229 XHG=2286 YBD=2759 YBD=2760 YBD=2768 YBD=2767 YHG=2740>expose YHG=2731>their YHG=2731>patients YHG=2731>with YHG=2731>heart YHG=2730>failure YHG=2738>to YHG=2738>constant YHG=2731>light YHG=2732>(or YHG=2732>perhaps XBD=179 XBD=240 XBD=270 XBD=348 XBD=425 XBD=581 XBD=760 XBD=825 XBD=1009 XBD=1117 XBD=1193 XHG=81 XHG=194 XHG=255 XHG=286 XHG=365 XHG=440 XHG=597 XHG=840 XHG=1024 XHG=1138 YBD=2774 YBD=2774 YBD=2775 YBD=2775 YBD=2780 YBD=2775 YHG=2747>search YHG=2755>a YHG=2746>safe YHG=2746>and YHG=2746>effective YHG=2753>treatment YHG=2746>for YHG=2746>childhood YHG=2740>ITP, YHG=2747>but XBD=1322 XBD=1490 XBD=1600 XBD=1698 XBD=1816 XBD=1958 XBD=1998 XBD=2157 XBD=2308 XBD=2419 XHG=1290 XHG=1348 XHG=1517 XHG=1627 XHG=1723 XHG=1842 XHG=1983 XHG=2024 XHG=2183 XHG=2334 YBD=2804 YBD=2808 YBD=2802 YBD=2811 YBD=2803 YHG=2782>to YHG=2781>constant YHG=2775>dark, YHG=2784>man YHG=2775>being YHG=2775>mainly YHG=2784>a YHG=2775>daytime YHG=2775>feeder), YHG=2784>more XBD=158 XBD=179 XBD=227 XBD=299 XBD=339 XBD=422 XBD=479 XBD=541 XBD=623 XBD=671 XBD=791 XBD=970 XBD=993 XBD=1053 XBD=1194 XHG=81 XHG=168 XHG=189 XHG=237 XHG=310 XHG=349 XHG=432 XHG=488 XHG=551 XHG=632 XHG=674 XHG=801 XHG=981 XHG=1003 XHG=1061 YBD=2818 YBD=2823 YBD=2819 YBD=2827 YBD=2818 YBD=2826 YBD=2824 YBD=2817 YBD=2818 YBD=2819 YHG=2790>since YHG=2789>I YHG=2790>do YHG=2796>not, YHG=2797>at YHG=2790>least YHG=2789>for YHG=2790>the YHG=2797>type YHG=2790>of YHG=2790>patient YHG=2790>described, YHG=2790>I YHG=2799>am YHG=2790>relieved XBD=1491 XHG=2394 XBD=1553 XBD=1628 XBD=1831 XBD=1930 XBD=1990 XBD=2057 XBD=2229 XBD=2373 XBD=2419 XHG=1290 YBD=2846 XHG=1513 XHG=1575 XHG=1649 XHG=1854 XHG=1952 XHG=2005 XHG=2079 XHG=2251 YBD=2847 YHG=2818>is YHG=2818>information YHG=2827>on YHG=2818>nutritional YHG=2825>state YHG=2818>of YHG=2818>the YHG=2819>hamsters YHG=2818>studied XBD=109 XHG=921 XBD=216 XBD=292 XBD=381 XBD=419 XBD=483 XBD=562 XBD=677 XBD=897 XBD=975 XBD=1099 XBD=1191 XHG=80 XHG=132 XHG=240 XHG=317 XHG=407 XHG=445 XHG=508 XHG=587 XHG=700 XHG=1000 XHG=1123 YBD=2862 YBD=2869 YBD=2861 YBD=2862 YBD=2863 YBD=2862 YHG=2839>to YHG=2833>point YHG=2840>out YHG=2833>that YHG=2833>I YHG=2833>do YHG=2840>not YHG=2833>think YHG=2833>Manoharan YHG=2833>has YHG=2833>found YHG=2843>one. XBD=1442 XHG=1290 YBD=2899 YHG=2862>required. XBD=265 XHG=864 XBD=439 XBD=493 XBD=677 XBD=762 XBD=848 XBD=980 XBD=1050 XBD=1117 XBD=1193 XHG=81 XHG=280 XHG=455 XHG=508 XHG=693 XHG=780 XHG=996 XHG=1063 XHG=1133 YBD=2906 YBD=2906 YBD=2905 YBD=2914 YBD=2906 YBD=2906 YBD=2913 YHG=2876>Manoharan YHG=2877>overlooks YHG=2886>an YHG=2877>important YHG=2877>fact. YHG=2877>The YHG=2878>patient YHG=2877>did YHG=2884>not YHG=2878>just

" XBD=1191 XBD=189 XHG=925 XBD=399 XBD=480 XBD=568 XBD=654 XBD=694 XBD=847 XBD=901 XBD=976 XBD=1083 XHG=81 XHG=213 XHG=424 XHG=504 XHG=593 XHG=679 XHG=719 XHG=872 XHG=1001 XHG=1107 YBD=2949 YBD=2955 YBD=2951 YBD=2950 YBD=2950 YHG=2920>receive YHG=2920>vincristine, YHG=2921>but YHG=2921>also YHG=2922>had YHG=2931>a YHG=2921>laxative YHG=2928>at YHG=2921>the YHG=2931>same YHG=2922>time.

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Cardiothoracic Institute,

P. H. SUGDEN London SW3 6HP XBD=1193XHG=921 XBD=249 XBD=366 XBD=473 XBD=576 XBD=685 XBD=829 XBD=890 XBD=958 XBD=1131 XHG=81 XHG=279 XHG=396 XHG=503 XHG=606 XHG=715 XHG=859 XHG=989 XHG=1161 YBD=3001 YBD=3001 YBD=2995 YBD=2994 YBD=2994 YBD=2994 YHG=2964>Purgatives YHG=2965>alone YHG=2965>have YHG=2966>long YHG=2966>been YHG=2965>known YHG=2973>to YHG=2966>be YHG=2965>effective YHG=2966>in XBD=287 XHG=836 XBD=375 XBD=468 XBD=618 XBD=674 XBD=820 XBD=947 XBD=1034 XBD=1145 XBD=1192 XHG=81 XHG=302 XHG=389 XHG=484 XHG=632 XHG=690 XHG=964 XHG=1050 XHG=1161 YBD=3037 YBD=3046 YBD=3038 YBD=3043 YBD=3038 YBD=3038 YHG=3009>iTP-indeed YHG=3009>they YHG=3018>were YHG=3009>extolled YHG=3010>by YHG=3010>Eustace YHG=3009>Smith, YHG=3010>who YHG=3016>wrote YHG=3010>in XBD=164 XHG=896 XBD=237 XBD=301 XBD=396 XBD=593 XBD=710 XBD=827 XBD=881 XBD=980 XBD=1147 XBD=1193 XHG=83 XHG=181 XHG=251 XHG=316 XHG=409 XHG=607 XHG=723 XHG=841 XHG=995 XHG=1161 YBD=3080 YBD=3080 YBD=3081 YBD=3082 YBD=3089 YBD=3090 YBD=3082 YHG=3053>1886: YHG=3052>&dquo;In YHG=3053>the YHG=3052>form YHG=3053>of YHG=3054>which YHG=3062>comes YHG=3063>on YHG=3053>quite YHG=3053>suddenly YHG=3054>in purpura LOW-SOLUTE ADAPTED MILK FORMULAE XBD=197 XHG=804 XBD=348 XBD=414 XBD=483 XBD=570 XBD=625 XBD=788 XBD=969 XBD=1009 XBD=1193 XHG=80 XHG=212 XHG=363 XHG=431 XHG=498 XHG=587 XHG=635 XHG=984 XHG=1025 YBD=3132 YBD=3132 YBD=3125 YBD=3133 YBD=3125 YBD=3134 YHG=3096>healthy YHG=3096>children YHG=3097>the YHG=3097>old YHG=3097>plan YHG=3096>of YHG=3097>energetic YHG=3096>purgation YHG=3097>is YHG=3097>peculiarly XBD=1514 XBD=1591 XBD=1633 XBD=1797 XBD=1863 XBD=1984 XBD=2132 XBD=2344 XBD=2419 XHG=1325 XHG=1535 XHG=1615 XHG=1658 XHG=1821 XHG=1886 XHG=2008 XHG=2155 XHG=2366 YBD=3174 YBD=3168 YBD=3175 YBD=3167 YHG=3140>SIR,-Your YHG=3140>Jan YHG=3140>4 YHG=3139>editorial YHG=3148>on YHG=3139>infant YHG=3139>feeding YHG=3139>emphasises YHG=3139>the XBD=275 XHG=974 XBD=302 XBD=371 XBD=467 XBD=513 XBD=601 XBD=721 XBD=867 XBD=965 XBD=989 XBD=1123 XBD=1193 XHG=79 XHG=286 XHG=311 XHG=379 XHG=476 XHG=516 XHG=609 XHG=729 XHG=875 XHG=998 XHG=1133 YBD=3168 YBD=3176 YBD=3169 YBD=3168 YBD=3177 YBD=3169 YHG=3139>valuable YHG=3139>few YHG=3140>doses YHG=3140>of YHG=3149>some YHG=3141>drastic YHG=3141>aperient YHG=3149>cause YHG=3149>a YHG=3147>prompt YHG=3141>and ... XBD=1481XHG=728 XBD=1537 XBD=1649 XBD=1791 XBD=1869 XBD=2083 XBD=2241 XBD=2416 XHG=1290 XHG=1500 XHG=1548 XHG=1667 XHG=1808 XHG=1886 XHG=2100 XHG=2258 YBD=3220 YBD=3219 YHG=3184>importance YHG=3184>of YHG=3184>breast YHG=3184>feeding YHG=3183>and YHG=3183>appropriate YHG=3184>weaning YHG=3184>practices. XBD=149 XBD=390 XBD=478 XBD=720 XBD=949 XBD=1029 XBD=1086 XBD=1107 XBD=1145 XBD=1193 XHG=80 XHG=158 XHG=399 XHG=487 XHG=960 XHG=1037 XHG=1095 XHG=1116 XHG=1154 YBD=3213 YBD=3213 YBD=3220 YBD=3221 YBD=3212 YBD=3212 YBD=3213 YHG=3184>final YHG=3184>disappearance YHG=3184>of YHG=3184>haemorrhagic YHG=3176>symptoms. YHG=3183>Nor YHG=3193>am YHG=3184>I YHG=3191>at YHG=3184>all all &dquo;2 XBD=1454 XBD=1518 XBD=1587 XBD=1663 XBD=1747 XBD=1795 XBD=1935 XBD=2008 XBD=2055 XBD=2132 XBD=2173 XBD=2282 XBD=2362 XBD=2419 XHG=1290 XHG=1466 XHG=1528 XHG=1598 XHG=1673 XHG=1758 XHG=1799 XHG=1945 XHG=2017 XHG=2064 XHG=2141 XHG=2182 XHG=2292 XHG=2371 YBD=3261 YBD=3255 YBD=3256 YHG=3228>However, YHG=3227>the YHG=3227>fact YHG=3227>that YHG=3228>95% YHG=3227>of YHG=3227>mothers YHG=3227>will YHG=3227>be YHG=3227>able YHG=3234>to YHG=3228>breast YHG=3227>feed YHG=3227>for XBD=143 XHG=887 XBD=225 XBD=419 XBD=463 XBD=554 XBD=706 XBD=795 XBD=868 XBD=959 XBD=1017 XBD=1142 XBD=1191 XHG=79 XHG=162 XHG=243 XHG=439 XHG=482 XHG=575 XHG=724 XHG=814 XHG=978 XHG=1036 XHG=1160 YBD=3255 YBD=3264 YBD=3257 YBD=3256 YBD=3256 YBD=3264 YHG=3236>sure YHG=3227>that YHG=3227>vincristine YHG=3227>is YHG=3227>safe. YHG=3227>Anyone YHG=3228>who YHG=3228>has YHG=3237>seen YHG=3228>its YHG=3228>ability XBD=207 XHG=701 XBD=242 XBD=413 XBD=627 XBD=681 XBD=929 XBD=1044 XBD=1190 XHG=79 XHG=226 XHG=261 XHG=433 XHG=646 XHG=949 XHG=1066 YBD=3306 YBD=3299 YBD=3307 YBD=3308 YBD=3300 YBD=3299 YHG=3271>produce YHG=3280>a YHG=3271>crippling YHG=3271>neuropathy YHG=3281>or YHG=3271>subcutaneous YHG=3271>tissue YHG=3271>&dquo;burn&dquo; XBD=1353 XBD=1492 XBD=1610 XBD=1687 XBD=1752 XBD=1828 XBD=1904 XBD=1979 XBD=2042 XBD=2152 XBD=2210 XBD=2375 XBD=2418 XHG=1289 XHG=1367 XHG=1505 XHG=1623 XHG=1701 XHG=1765 XHG=1840 XHG=1918 XHG=1990 XHG=2054 XHG=2163 XHG=2221 XHG=2386 YBD=3305 YBD=3300 YBD=3307 YBD=3308 YBD=3299 YHG=3272>4-6 YHG=3270>months YHG=3280>means YHG=3271>that YHG=3272>5% YHG=3271>will YHG=3278>not, YHG=3272>and YHG=3271>the YHG=3271>desire YHG=3272>(or YHG=3272>pressure) YHG=3278>to XBD=1395 XBD=1440 XBD=1537 XBD=1611 XBD=1675 XBD=1755 XBD=1806 XBD=2051 XBD=2204 XBD=2246 XBD=2343 XBD=2418 XHG=1289 XHG=1409 XHG=1453 XHG=1551 XHG=1624 XHG=1689 XHG=1768 XHG=1812 XHG=2064 XHG=2217 XHG=2259 XHG=2355 YBD=3350 YBD=3342 YBD=3343 YHG=3321>return YHG=3320>to YHG=3314>and YHG=3314>the YHG=3314>lack YHG=3314>of YHG=3315>child-minding YHG=3314>facilities YHG=3321>at YHG=3315>work YHG=3315>will XBD=149 XHG=966 XBD=375 XBD=487 XBD=533 XBD=664 XBD=748 XBD=787 XBD=956 XBD=978 XBD=1122 XBD=1192 XHG=79 XHG=158 XHG=383 XHG=495 XHG=542 XHG=672 XHG=755 XHG=796 XHG=988 XHG=1132 YBD=3342 YBD=3351 YBD=3343 YBD=3350 YBD=3342 YBD=3350 YHG=3314>after YHG=3314>extravasation YHG=3314>would YHG=3315>be YHG=3315>equally YHG=3315>hard YHG=3321>to YHG=3315>persuade, YHG=3315>I YHG=3321>suspect, YHG=3315>and XBD=89 XHG=78 XBD=197 XBD=346 XBD=453 XBD=506 XBD=550 XBD=670 XBD=844 XBD=890 XBD=1022 XBD=1099 XBD=1191 XHG=105 XHG=212 XHG=362 XHG=467 XHG=513 XHG=565 XHG=683 XHG=858 XHG=905 XHG=1037 XHG=1114 YBD=3384 YBD=3394 YBD=3387 YBD=3386 YBD=3386 YHG=3357>I YHG=3358>doubt YHG=3357>whether YHG=3366>many YHG=3358>of YHG=3367>us YHG=3358>would YHG=3358>volunteer YHG=3365>to YHG=3358>receive YHG=3358>this YHG=3358>drug XBD=1349 XBD=1396 XBD=1463 XBD=1553 XBD=1601 XBD=1759 XBD=1847 XBD=1961 XBD=2018 XBD=2174 XBD=2274 XBD=2351 XBD=2418 XHG=1289 XHG=1364 XHG=1411 XHG=1478 XHG=1568 XHG=1617 XHG=1777 XHG=1862 XHG=1977 XHG=2033 XHG=2190 XHG=2290 XHG=2365 YBD=3385 YBD=3394 YBD=3386 YHG=3358>add YHG=3364>to YHG=3357>the YHG=3357>total YHG=3357>in YHG=3358>practice. YHG=3358>The YHG=3358>infant YHG=3367>on YHG=3358>artificial YHG=3358>feeds YHG=3359>and YHG=3358>the XBD=225 XHG=840 XBD=271 XBD=381 XBD=447 XBD=551 XBD=626 XBD=709 XBD=758 XBD=825 XBD=937 XBD=1010 XBD=1140 XBD=1191 XHG=78 XHG=241 XHG=287 XHG=396 XHG=463 XHG=568 XHG=641 XHG=723 XHG=772 XHG=955 XHG=1027 XHG=1154 YBD=3429 YBD=3437 YBD=3438 YBD=3430 YBD=3429 YBD=3431 YBD=3429 YHG=3401>ourselves YHG=3408>to YHG=3410>prove YHG=3401>point YHG=3411>one YHG=3411>way YHG=3411>or YHG=3401>the YHG=3402>other. YHG=3401>We YHG=3402>should YHG=3402>be XBD=1472 XBD=1622 XBD=1757 XBD=1916 XBD=1988 XBD=2257 XBD=2417 XHG=1289 XHG=1482 XHG=1632 XHG=1768 XHG=1927 XHG=1997 XHG=2268 YBD=3429 YBD=3437 YBD=3438 YBD=3430 YHG=3401>interaction YHG=3401>between YHG=3401>feeding YHG=3402>practices YHG=3402>and YHG=3401>gastrointestinal YHG=3402>infection XBD=196 XHG=829 XBD=285 XBD=352 XBD=426 XBD=507 XBD=575 XBD=655 XBD=815 XBD=867 XBD=1015 XBD=1106 XBD=1192 XHG=78 XHG=212 XHG=300 XHG=368 XHG=443 XHG=523 XHG=590 XHG=672 XHG=876 XHG=1031 XHG=1122 YBD=3474 YBD=3473 YBD=3482 YBD=3474 YBD=3474 YHG=3451>content YHG=3444>with YHG=3444>fact YHG=3445>that YHG=3445>the YHG=3451>vast YHG=3445>majority YHG=3445>of YHG=3445>children YHG=3445>with YHG=3445>ITP XBD=1367 XBD=1434 XBD=1645 XBD=1688 XBD=1779 XBD=1941 XHG=1288 XHG=1381 XHG=1448 XHG=1656 XHG=1701 XHG=1792 YBD=3481 YBD=3473 YBD=3483 YBD=3474 YHG=3454>were YHG=3451>not YHG=3445>emphasised YHG=3445>in YHG=3454>your YHG=3446>editorial.