Neuropsychopharmacology of the trace amines, experimental and clinical aspects

Neuropsychopharmacology of the trace amines, experimental and clinical aspects

Journal of the Neurological Sciences, 1987, 79:345-348 345 Elsevier Book Reviews Comparative Neurobiology of the Basal Ganglia, A. Parent (ed.), W...

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Journal of the Neurological Sciences, 1987, 79:345-348

345

Elsevier

Book Reviews

Comparative Neurobiology of the Basal Ganglia, A. Parent (ed.), Wiley Series in Neurobiology, John Wiley & Sons, N.Y., Chichester, 1986 This monograph gathers recently acquired knowledge on the basal ganglia in mammals and in non-mammalian vertebrates, mainly based on the matrix of immunohistochemical and neuroanatomical data. In this way, the basic structural and functional design of these complex structures is put in their proper perspective. The phylogeny, organisation in lower and higher vertebrates is first set out in detail and followed by a synthetic synopsis. The heterogenous mammalian striatum is then analysed in depth, as well as the nigra, closing with a penetrating look at the limbic and striatal balance. A most illuminating, reliable and thought provoking test, which rewards even the neurologist pre-oceupied with movement disorders to re-think traditional concepts. Extremely well-indexed. Unreservedly recommended reading. G.W. BRUYN

Neuropsychopharmacology of the Trace Amines, Experimental and Clinical Aspects, A. A. Boulton, P. R. Bieck, L. Maitre, P. Riederer (eds.), Humana Press, Clifton, New Jersey, 1985 This monograph is a collection of papers presented at the 2nd Trace Amine Symposium, May 1985. In some thirty papers on experimental research the effects of trace amines on behaviour, and on neurotransmission are enlarged upon, specifically the effects of phenylethylamine, tryptamine, and octopamine. Their catabolism as possible alternative metabolic pathways for some aminoacids are set out. In 15 clinical pharmacological papers the effects are analysed of the trace amines and their metabolites, such as on aggression, attention, depression, etc. The expert in this field will certainly use the book as a handy reference source, the interested clinician whether psychiatrist or neurologist, will find a wealth of detail quickly to be absorbed. G.W. BRUYN

New Brain Imaging Techniques and Psychopharmacology, M.R. Trimble (ed.), Brit. Assoc. Psychopharmacol, Monograph No. 9, Oxford University Press, Oxford, N.Y., Tokyo, 1986 This small monograph surveys recent techniques such as 2-deoxyglucose autoradiography, PET-scanning and its implications for neurological and psychiatric disorders (such as epilepsy, dementia, schizophrenia, Parkinsonism, etc.), 133xenon-inhalation assays of cerebral blood flow, and NMR. Published early in 1986, the text, by keeping to basics, has not become outdated. A useful introduction. G.W. BRUYN 0022-510X/87/$03.50 © 1987 Elsevier Science Publishers B.V. (Biomedical Division)