New Prescription Products

New Prescription Products

Prescription Practice New Prescription Products Cardrase Tablets Description: Each tablet contains 125 mg. ethoxzolamide (6-ethoxybenzothiazole-2-sul...

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Prescription Practice

New Prescription Products Cardrase Tablets Description: Each tablet contains 125 mg. ethoxzolamide (6-ethoxybenzothiazole-2-sulfonamide) . Indications: Diuretic in mild to moderate congestive heart failure. It inhibits the enzyme carbonic anhydrase. Administration: Orally, 62.5 to 125 mg. in a single dose after breakfast for 3 consecutive days of each week, or on alternate days. Form Supplied: Bottles of 25 and 100. Source: The Upjohn Co., Kalamazoo, Mich. Chel-Iron Tablets Chel-Iron Drops Description: Each tablet supplies 330 mg. iron choline citrate complex (40 mg. Fe). Each cc. of the pediatric drops contains 133 mg. iron choline citrate (16 mg. Fe). Indications: As a hematinic. A dministration: As directed by the physician. Form SUPPlied: Tablets in bottles of 100. Source: Kinney & Co., Inc., Columbus, Ind.

Dulcolax Tablets Dulcolax Suppositories Description: Each yellow entericcoated tablet contains 5 mg. and each suppository contains 10 mg. of Dulcolax, bis(p-acetoxy phenyl)-2-pyridylmethane, which is practically insoluble in intestinal juices. Indications: For relief in all types of constipation. Administration: Tablets, 1 to 3 at bedtime for morning b.m., or 30 minutes before breakfast for b.m. within 6 hrs.; Suppositories, 1 at time action is required. Form Supplied: Tablets, boxes of 6 and bottles of 100; Suppositories, boxes of 6. Source: Geigy Pharmaceuticals, Ardsley, N.Y. Leritine Tablets Leritine Iniection Description: Each oral tablet contains 25 mg. Leritine (anileridine) as the di-

hydro chloride. Each cc. of injection (with or without 0.9% benzyl alcohol) contains 25 mg. anileridine as the phosphate. Chemically, anileridine is ethyl1 - (4 - aminophenethyl) - 4 - phenylisonipecotate or 1 - [{1- (p - aminophenyl)ethyl]-4-phenyl-4-carbethoxypiperidine. Indications: A synthetic narcotic drug for relief of more severe pain. Administration: Orally, 25 mg., repeated every 6 hrs. if necessary. Injection, s.c. or i.m., 25-50 mg. The injection also may be given by i.v. infusion. Form Supplied: Tablets, bottles of 100 and 500. Injection (plain), 1-cc. and 2-cc. ampuls, both in boxes of 25 and 100. Injection (w/ benzyl alcohol 0.9%), 30-cc. rubber-capped vial. Narcotic order required for all forms. Source: Merck Sharp & Dohme, Philadelphia, Pa.

Meticortelone Soluble for Iniection Description: Each vial contains 50 mg. prednisolone (as hemisuccinate) as a buffered sterile powder to be dissolved in 2 cc. of sterile water or saline before use. Indications: For certain cases of shock which are unresponsive to standard antishock therapy; acute allergic or asthmatic reactions; acute adrenocortical insufficiency and in cases of bilateral adrenalectomy, both prophylactically and in crisis; severe infections with overwhelming toxemia, to stabilize the patient until specific antibiotics can take effect. Administration: By i.v. injection or i.v. drip infusion. Corticosteroid effect is provided within an hour after administration. Form Supplied: Individual packages, 25, 50, and 100 per box. Source: Schering Corporation, Bloomfield, N.]. Promyl Tablets Description: Each scored, yellow tablet contains: 5 mg. pipenzolate methylbromide (N -methyl-N -ethyl-3piperidinium benzilate methylbromide) , 300 mg. aluminummagnesium hydroxycarbonate, and 200 mg. aluminum proteinate.

Indir;ations: For reduction of excess gastric acidity, reduction of gastrointestinal spasm, and return of gastric secretion toward normal in control of ulcer pain. Administration: As directed by physician. Form Supplied: Bottles of 100 tablets. Source: Crookes-Barnes Labs., Inc., Wayne, N.].

Other New Products Chemicals, clinical trial drugs, diagnostic aids, equipment for the retail and hospital pharmacy.

ABDEC Drops Modified Parke, Davis & Co. has modified the formula of its ABDEC polyvitamin drops by increasing in each 0.6 cc.: B2 from 0.4 mg. to 1.2 mg.; pantothenic from 2 mg. to 5 mg.; nicotinamide from 5 mg. to 10 mg.; and by the new addition of Bl2 2 mcg./ 0.6 cc. The other ingredients (A, D, B I , B6, C) are retained in the same amounts. Supplied in 15-cc. and 50-cc. bottles with droppers. ADC Drops w /8 6 An aqueous, nonalcoholic, orange-lime solution containing, in each 0.6 cc.: vitamin A, 1.5 mg. (5,000 u.); D, 25 mcg. (1,000 u.); C, 50 mg.; and B6, 1 mg., is marketed by Parke, Davis & Co. for use in the prevention and treatment of vitamin deficiencies, particularly in children. Daily dosage for infants under 1 yr. is 0.3 cc.; for older children and adults, 0.6 cc.; dose may be dropped on tongue or mixed with milk, fruit juices, or other foods. Supplied in 15cc. and 50-cc. bottles with graduated dropper. Alphosyl Lotion A cream-colored, greaseless and stainless lotion containing a coal tar extract and allantoin is marketed by Reed & Carnrick for use in control of psoriasis. The o-t-c product is supplied in 8-oz. bottles.

Adrestat (F) Iniection-New Units Organon Inc. has added 5-cc. multiple-

All actively promoted items on which information has been received in the past thirty days are reported here. Manufacturers are urged to send details of their new products as early as possible, so that pharmacists through these pages will have full information before products ~re detailed to the physician. For inclusion in this department, for which there Is no charge, send descriptive literature to the Editor, New PreSCription Products Department, JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION, 2215 Constitution Avenue, N.W., Washington 7, D.C.

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dose vials and l-cc. disposable syringe units of the solution containing in each cc. : 5 mg. adrenochrome semicarbazone (available as 130 mg. carbazochrome salicylate) to its Adrestat (F) line. The drug is used for prevention and control of bleeding. Becetax-Formerly Beceiex The parenteral aqueous solution of vitamin B complex factors with vitamin C, formerly marketed as Becejex, is now marketed by Winthrop Laboratories under the trade name Becetax injection. Supplied in multiple-dose 10-cc. vials in boxes of 1 and 10 vials. Bio-Cuta Crea m A cream, containing in each Gm.: neomycin base, 2.5 mg., and gramicidin, 0.25 mg., in a pH 4.5 buffered base, is marketed by Columbus Pharmacal Co. for antibiotic use in cutaneous bacterial infections associated with eczema, impetigo, boils, burns, otitis externa, and conjunctivitis. Supplied in I-oz. tubes. Butyl Chloride Capsules (Vet.) Veterinary capsules containing, in each, 1 cc. (884 mg.) butyl chloride, are marketed by West-ward for use as an an thelmin tic in the destruction and expulsion of ascarids and hookworms in puppies and other animals weighing 10 to 40 lbs. Supplied ln bottles of 100 capsules. Chlor-Trimeton Compound Repetabs Schering Corp. has marketed tablets containing, in each: 4 mg. ChlorTrimeton (chlorp heniramine) maleate and 20 mg. phenylephrine, with half the amount of each in an outer layer and half in an inner core which is surrounded by a slow disintegration barrier. Recommended for relief of nasal congestion associated with colds, allergic rhinitis, and acute sinusitis, the tablets are supplied in bottles of 100.

Dainite Aminophylline Tablet Unit Irwin, Neisler & Co. has marketed a combination package containing 50 day tablets and 20 night tablets. Each pink day tablet contains: sod. phenobarbital, 0.25 gr.; aminophylline, 3 gr.; ephedrine HCI, 0.25 gr.; ethyl aminobenzoate, 0.25 gr. ; and aluminum hydroxide, 2.5 gr. Each black night tablet contains: phenobarbital, 0.38 gr.; sod. phenobarbital, 0.5 gr.; aminophylline, 4 gr.; ethyl aminobenzoate, 0.25 gr.; and aluminum hydroxide, 2.5 gr. Dosage: day, 1-2 tablets 3 times daily before meals; night, 1-2 tablets at 10 P.M. Delta-Albaplex Capsules (Vet.) Veterinary capsules containing, in each: tetracycline phosphate complex equivalent to tetracyline HCI, 60 mg.; Albamycin (as novobiocin sodium), 60 mg.; and Delta-Cortef (prednisolone), 1.5 mg., are marketed by Upjohn Co. as an oral antibiotic-corticosteroid combination in small animal medicine. Supplied in bottles of 16 and 100 capsules. Enzadin Cream A cream containing 250 mg. Enzactin (triacetin, glyceryl triacetate) in an emollient base is marketed by Ayersl Laboratories for use as an antifungal agent in athlete's foot and ringworm of the scalp. It is applied locally twice daily. Supplied in l-oz tubes. Erucyte Tablets Erucyte Neotabs Red sugar-coated tablets containing, in each: ferrous fumarate, 200 mg.; ascorbic acid, 125 mg.; and vitamin B 12, 2 mcg., are marketed by E. S. Milter Labs. for use in iron deficiency anemia. Dosage, 1 tablet 2 or 3 times a day. Supplied in bottles of 100 and 1,000. Each flavored N eotab contains 100 mg., 50 mg., and 5 mcg., respectively, of the above ingredients. Dosage same as tablets. Supplied in bottles of 100 and 1,000. Lotioblanc

Clistin R-A Tablets 12 mg. Yellow coated tablets, each containing G mg. Clistin (carbinoxamine) maleate in an outer coating and 6 mg. in an inner core for delayed action, are marketed by McNeil Laboratories for use in symptomatic relief of difficult allergic disorders. Dosage, 1 tablet is usually effective for 12 hrs. Supplied in bottles of 50.

A lotion combining zinc sulfate and sulfurated potash according to the USP method for white lotion, but with the addition of inert stabilizing agents for uniform dispersion, is marketed by Arnar-Stone Laboratories. Supplied in 4-oz. bottles.

Combid Spansule Caps.-250 Bottle The S K & F anticholinergic-tranquilizing combination of Darbid (isopropamide), 5 mg., and Compazine (prochlorperazine), 10 mg., in each Spansule capsule is now supplied in bottles of 2.50 capsules in addition to the bottles of 30.

Nupercainal Lotion Ciba PharmaceUlical Products has marketed a lotion containing 0.5% Nu~ercaine (dibucaine). SUIlPlied m squeeze bottles. See pp. 183, 255 Syntussin Tablets Tablets containing, in each: chlor-

pheniramine maleate, :2 mg.; phenylephrine HCI, 7.5 mg.; dextromethorphan HBr, 10 rr.g.; and terr;in hydrate, 64.8 mg., are marketed by Ives-Cameron Co. for use in the symptomatic control of CJlds, upper respiratory infections, and allergies. Dosage, initially 2 tablets, then 1 tablet every 3 or 4 hrs . Drowsiness may occur. Supplied in bottles of 48 tablets. Tetrad Elixir An elixir containing, in each 5-cc. teaspoonful: pentylenetetrazol, 100 mg.; nicotinic acid, 50 mg.; tetraiodothyronine, 10 mcg.; methyltestosterone, 1 mg.; and ethinyl estradiol, 0.002 mg., in a wine base, is marketed by E. S. Miller Labs. for use in pregeriatric and geriatric disorders. Dosage, 1 teaspoonful 3 times a day. Supplied in pints and gallons. Tussaminic Tablets Tablets containing, in each: phenylpropanolamine HCI, 50 mg.; pyrilamine maleate, 25 mg.; pheniramine maleate, 25 mg.; dextromethorphan HBr, 30 mg.; and terpin hydrate, 300 mg., with half these ~mounts in the outer layer and half in the inner core of the tablet, are marketed by SmithDorsey for oral use as a respiratory dec::mgestant, antitussive, and expectorant. Dosage, 1 tablet in the morning, midafternoon, and at bedtime. Supplied in bottles of 50. Uristix Reagent Strips Paper strir;s the ends of which are impregnated with reagents that give tests for proteinuria and for glycosuria (the two test portions being separated by a barrier on the strip) are marketed by Ames Company. Positive tests obtained after dipping the strip into the urine specimen are compared to the color guide on the bottle label. U ristix is supplied in bottles of 125 strips. Vasodiatol Tablets Tablets containing, in each, 10 mg. or 20 mg. (scored) pentaerythritol tetranitrate are marketed by Rowell Laboratories for use as a vasodilator to prevent anginal attacks. Not intended for relief of acute attack. Dosage, orally, 10-20 mg. 3- 4 times daily before meals and at bedtime. Supplied, both strengths in bottles of 100, 500, and 1,000, and in drums of 5,000 tablets. Vaso-Tabs Tablets containing, in each pentylenetetrazole, 100 mg., and nicotinic acid, 50 mg., are marketed by Paul Maney Labs. for use as a cerebral vascular stimulant for debilitated or convalescing pers Jns, and for elderly persons suffering from senility, apathy, fatigue states, and mental confusion. D osage, 1- 3 tablets 3 times daily. Supplied in bottles of 100 and 1,000.

VOL. 19, NO.5, MAY, 1958/ PRACTICAL PHARMACY EDITION

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