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No. 77 Frenchay Aphasia Screening Test Validity in Post Stroke Colombian Patients
PM&R
and validity are properties of instruments that affect credibility of the rehabilitation process. The objectives of this study are identify stroke rehabilitation arm function domain of scales that have been validated to Brazilian cultural context and classify them using the International Classification of Functioning Disability and Health (ICF). Methods: Literature review was performed including sources from 1980 to 2013 from Medline (scale [MESH] or assessment or evaluation or measurement or Brazil or Portuguese) LILACS (stroke and evaluation and (instance:“regional”)) and SCIELO (stroke and evaluation) databases. Only stroke patients and validation studies in Brazilian cultural context of stroke assessment scales that contain a function arm domain were selected. Data extraction: after reviewing the 7778 abstracts resulting from searching, 13 papers have been selected. Five independent researchers have analyzed the articles. One study has been excluded because it does not contain an arm function evaluation and the other because the study doesn’t involve the Brazilian cultural context. Findings: 11 different scales (Jebsen-Taylor test, stroke impact scale, Rankin scale, functional independence measure, Barthel index, NIHSS motor activity log, Wolf motor function test, Fugl-Meyer assessment, Scandinavian stroke scale, Nottingham sensory assessment for stroke patients). Interpretation: Only 11 commonly used scales that evaluated the arm function are validated in Brazilian cultural context. Future studies should also include instrumental evaluation according to the participation ICF domain.
No. 77 Frenchay Aphasia Screening Test Validity in Post Stroke Colombian Patients. Camilo Chaves; Ma. De Los Angeles Tamayo, SLP; Fernando Ortiz. Disclosure: None. Objective: To establish the validity of the Frenchay aphasia screening test (FAST) in Colombian population to establish the criterion validity of the FAST by comparing it with a diagnostic and evaluation aphasia battery. Setting: Inpatient post stroke adult population in Bogota, Colombia. Participants: 65 patients (men and women) older than 18 years who were hospitalized because of first-time stroke within a 30 day course. Interventions: We applied the FAST in the stroke patients in two different times and by two different observers. To a 10 patient subgroup we applied the Boston diagnostic aphasia examination. Then we compared the results between the two FAST observers and between the FAST and the Boston diagnostic aphasia examination to establish the validity criterion and the interobserver validity of the FAST. Main Outcome Measures: Interrater validity of the FAST, FAST and Boston diagnostic aphasia examination, correlation time of the FAST application. Results: The kappa index between the FAST interobserver application was 0.8 or greater. When comparing the FAST and the Boston diagnostic aphasia examination the Spearman correlation was of at least 0.6. The FAST application time was between 5-10 minutes. Conclusions: The FAST showed an excellent interrater validity. The FAST showed a good correlation with the Boston diagnostic aphasia examination. The FAST was an easy and brief tool for screening aphasia.
No. 79 Association of CASP Gene Polymorphisms and Ischemic Stroke. Jinmann Chon; Minho Park; Seung Yeol Lee. There are several evidences of the correlation between apoptosis and ischemic stroke (IS). Apoptosis can influence neuronal cell death and neuroprotection of brain tissue thereby may have effect on the development and clinical severity of IS. The purpose of this study is to investigate whether the polymorphisms of CASP 3 gene (rs4647602; intron A/C and rs1049216; UTR C/T) and CASP9 (RS1052576; Gln/Arg G/A and rs1052571; Ser/Val T/C) were associated with the development, clinical severity and daily activities in IS. Genomic DNA from 110 IS patients and 201 healthy control subjects were extracted and polymerase chain reaction products were sequenced. In order to investigate the association of polymorphisms and
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the development modified Barthel index (K-MBI) score and National Institutes of Health Stroke Scale (k-NIHSS), multiple logistic regression models were analyzed. These results revealed that a single nucleotide polymorphism (SNP) of CASP3 (RS1049216; UTR C/T) and a missensce SNP of CASP9 (rs1052571; Ser/Val T/C) was associated with the development of IS. Polymorphism of untranslational region of CASP3 (RE1049216) has association with the development of IS (in codominant1 model OR¼ 0.51 95% CI¼0.29-0.88 p¼0.017 in dominant model OR¼0.57 95% CI¼0.34-0.97 p¼0.034 in overdominant model OR¼0.50 95% CI¼0.29-0.87 p¼0.011). A missense SNP of CASP9 gene (rs1052571 Ser/Val) was associated with the development of IS (OR¼1.93 95% CI¼1.05-3.55 p¼0.034 in recessive model). These results indicate the possibility that CASP3 and CASP9 gene CASP3 (RS1049216 and RS1052571) is a marker for the development of IS. No. 80 Programa de Terapia Cognitiva Integral en Pacientes Con Afectación Cognitiva Secundaria a Enfermedad Vascular Cerebral Isquémica. David Adrian Delgado Ruiz; Dra. Ofelia Martinez Villa. Divulgación: Ninguna. Objetivo: Mejorar el déficit cognitivo de los pacientes con enfermedad vascular cerebral isquémica. Diseño: Estudio observacional prospectivo longitudinal de cohorte. Configuración: programa de terapia cognitiva con una evaluaciones inicial y final. Nivel de evidencia: IIB - III. Participantes: Treinta y cinco hombres y doce mujeres (47 pacientes) con diagnóstico de enfermedad vascular cerebral y déficit cognitivo de ambos sexos edad de 40 a 70 años. Se valoró el estado cognitivo inicial y final con el test de minimental el test pfeiffer y la prueba del reloj. Se aplicó el programa de terapia cognitiva por 20 sesiones consistió en actividades cognoscitivas memoria gnosias y praxias cálculo y funciones ejecutivas atención razonamiento y lenguaje. Principales medidas: Los resultados se analizaron con el paquete estadístico spssv.10 mediante la prueba de Wilcoxon (significancia p<0.05). Resultados: En la evaluación inicial del nivel cognitivo con los test MSSE Pfeiffer y prueba de reloj se encontró predominio del déficit leve en un 74.46%. Las áreas que mostraron más afectación de acuerdo a test de MSSE fueron la orientación memoria inmediata atención y calculo recuerdo diferido lenguaje y construcción. Al finalizar el programa de terapia cognitiva integral el déficit leve mejoró en un 61.7%. En relación con la mejoría de las funciones valoradas el porcentaje que se encontró mediante el test de prueba de reloj fue de un 60.1% para las funciones visoperceptivas visomotoras visoconstructivas planificación y ejecución motoras expresadas en cada una de las pruebas valoradas con una significancia estadística de p < de 0.05. Conclusión: El programa de terapia integral cognitiva mejora el deterioro cognitivo en pacientes con enfermedad vascular cerebral isquémica.
No. 81 Realidad Virtual Como Terapia Complementaria en el Tratamiento De Pacientes Con Parálisis Cerebral Infantil En Edad Escolar. David Adrian Delgado Ruiz; Dra. Amparo Asenath Lugo Calles; Irene Rodríguez Ramírez. Divulgación: Ninguna. Objetivo: Valorar el beneficio en independencia funcional utilizando la escala weeFIM con el uso de realidad virtual como terapia complementaria en pacientes con parálisis cerebral infantil. Diseño: Estudio cuasiexperimental descriptivo no ciego longitudinal y prospectivo. Nivel de evidencia: II Y III. Participantes: Incluimos 6 pacientes con las siguientes características: derechohabientes en edad escolar diagnóstico PCI clasificación funcional motora gruesa grados i al iii clasificación topográfica de hemiparesia con puntaje 0 a 2 escala tardieu. Resultados: Realizamos una valoración inicial y final se aplicaron 10 sesiones de terapia con el uso de la consola wii y el software wii Sports en juegos de baseball y box durante 20 minutos por sesión. Se realizó una evaluación final y análisis estadístico de los resultados con el paquete SPSS bajo un nivel de confianza de 95% con las pruebas de chi cuadrado y de Friedman con el coeficiente de concordancia de Kendall obtuvimos
and validity are properties of instruments that affect credibility of the rehabilitation process. The objectives of this study are identify stroke rehabilitation arm function domain of scales that have been validated to Brazilian cultural context and classify them using the International Classification of Functioning Disability and Health (ICF). Methods: Literature review was performed including sources from 1980 to 2013 from Medline (scale [MESH] or assessment or evaluation or measurement or Brazil or Portuguese) LILACS (stroke and evaluation and (instance:“regional”)) and SCIELO (stroke and evaluation) databases. Only stroke patients and validation studies in Brazilian cultural context of stroke assessment scales that contain a function arm domain were selected. Data extraction: after reviewing the 7778 abstracts resulting from searching, 13 papers have been selected. Five independent researchers have analyzed the articles. One study has been excluded because it does not contain an arm function evaluation and the other because the study doesn’t involve the Brazilian cultural context. Findings: 11 different scales (Jebsen-Taylor test, stroke impact scale, Rankin scale, functional independence measure, Barthel index, NIHSS motor activity log, Wolf motor function test, Fugl-Meyer assessment, Scandinavian stroke scale, Nottingham sensory assessment for stroke patients). Interpretation: Only 11 commonly used scales that evaluated the arm function are validated in Brazilian cultural context. Future studies should also include instrumental evaluation according to the participation ICF domain.
No. 77 Frenchay Aphasia Screening Test Validity in Post Stroke Colombian Patients. Camilo Chaves; Ma. De Los Angeles Tamayo, SLP; Fernando Ortiz. Disclosure: None. Objective: To establish the validity of the Frenchay aphasia screening test (FAST) in Colombian population to establish the criterion validity of the FAST by comparing it with a diagnostic and evaluation aphasia battery. Setting: Inpatient post stroke adult population in Bogota, Colombia. Participants: 65 patients (men and women) older than 18 years who were hospitalized because of first-time stroke within a 30 day course. Interventions: We applied the FAST in the stroke patients in two different times and by two different observers. To a 10 patient subgroup we applied the Boston diagnostic aphasia examination. Then we compared the results between the two FAST observers and between the FAST and the Boston diagnostic aphasia examination to establish the validity criterion and the interobserver validity of the FAST. Main Outcome Measures: Interrater validity of the FAST, FAST and Boston diagnostic aphasia examination, correlation time of the FAST application. Results: The kappa index between the FAST interobserver application was 0.8 or greater. When comparing the FAST and the Boston diagnostic aphasia examination the Spearman correlation was of at least 0.6. The FAST application time was between 5-10 minutes. Conclusions: The FAST showed an excellent interrater validity. The FAST showed a good correlation with the Boston diagnostic aphasia examination. The FAST was an easy and brief tool for screening aphasia.
No. 79 Association of CASP Gene Polymorphisms and Ischemic Stroke. Jinmann Chon; Minho Park; Seung Yeol Lee. There are several evidences of the correlation between apoptosis and ischemic stroke (IS). Apoptosis can influence neuronal cell death and neuroprotection of brain tissue thereby may have effect on the development and clinical severity of IS. The purpose of this study is to investigate whether the polymorphisms of CASP 3 gene (rs4647602; intron A/C and rs1049216; UTR C/T) and CASP9 (RS1052576; Gln/Arg G/A and rs1052571; Ser/Val T/C) were associated with the development, clinical severity and daily activities in IS. Genomic DNA from 110 IS patients and 201 healthy control subjects were extracted and polymerase chain reaction products were sequenced. In order to investigate the association of polymorphisms and
Vol. 6, Iss. 8S2, 2014
S111
the development modified Barthel index (K-MBI) score and National Institutes of Health Stroke Scale (k-NIHSS), multiple logistic regression models were analyzed. These results revealed that a single nucleotide polymorphism (SNP) of CASP3 (RS1049216; UTR C/T) and a missensce SNP of CASP9 (rs1052571; Ser/Val T/C) was associated with the development of IS. Polymorphism of untranslational region of CASP3 (RE1049216) has association with the development of IS (in codominant1 model OR¼ 0.51 95% CI¼0.29-0.88 p¼0.017 in dominant model OR¼0.57 95% CI¼0.34-0.97 p¼0.034 in overdominant model OR¼0.50 95% CI¼0.29-0.87 p¼0.011). A missense SNP of CASP9 gene (rs1052571 Ser/Val) was associated with the development of IS (OR¼1.93 95% CI¼1.05-3.55 p¼0.034 in recessive model). These results indicate the possibility that CASP3 and CASP9 gene CASP3 (RS1049216 and RS1052571) is a marker for the development of IS. No. 80 Programa de Terapia Cognitiva Integral en Pacientes Con Afectación Cognitiva Secundaria a Enfermedad Vascular Cerebral Isquémica. David Adrian Delgado Ruiz; Dra. Ofelia Martinez Villa. Divulgación: Ninguna. Objetivo: Mejorar el déficit cognitivo de los pacientes con enfermedad vascular cerebral isquémica. Diseño: Estudio observacional prospectivo longitudinal de cohorte. Configuración: programa de terapia cognitiva con una evaluaciones inicial y final. Nivel de evidencia: IIB - III. Participantes: Treinta y cinco hombres y doce mujeres (47 pacientes) con diagnóstico de enfermedad vascular cerebral y déficit cognitivo de ambos sexos edad de 40 a 70 años. Se valoró el estado cognitivo inicial y final con el test de minimental el test pfeiffer y la prueba del reloj. Se aplicó el programa de terapia cognitiva por 20 sesiones consistió en actividades cognoscitivas memoria gnosias y praxias cálculo y funciones ejecutivas atención razonamiento y lenguaje. Principales medidas: Los resultados se analizaron con el paquete estadístico spssv.10 mediante la prueba de Wilcoxon (significancia p<0.05). Resultados: En la evaluación inicial del nivel cognitivo con los test MSSE Pfeiffer y prueba de reloj se encontró predominio del déficit leve en un 74.46%. Las áreas que mostraron más afectación de acuerdo a test de MSSE fueron la orientación memoria inmediata atención y calculo recuerdo diferido lenguaje y construcción. Al finalizar el programa de terapia cognitiva integral el déficit leve mejoró en un 61.7%. En relación con la mejoría de las funciones valoradas el porcentaje que se encontró mediante el test de prueba de reloj fue de un 60.1% para las funciones visoperceptivas visomotoras visoconstructivas planificación y ejecución motoras expresadas en cada una de las pruebas valoradas con una significancia estadística de p < de 0.05. Conclusión: El programa de terapia integral cognitiva mejora el deterioro cognitivo en pacientes con enfermedad vascular cerebral isquémica.
No. 81 Realidad Virtual Como Terapia Complementaria en el Tratamiento De Pacientes Con Parálisis Cerebral Infantil En Edad Escolar. David Adrian Delgado Ruiz; Dra. Amparo Asenath Lugo Calles; Irene Rodríguez Ramírez. Divulgación: Ninguna. Objetivo: Valorar el beneficio en independencia funcional utilizando la escala weeFIM con el uso de realidad virtual como terapia complementaria en pacientes con parálisis cerebral infantil. Diseño: Estudio cuasiexperimental descriptivo no ciego longitudinal y prospectivo. Nivel de evidencia: II Y III. Participantes: Incluimos 6 pacientes con las siguientes características: derechohabientes en edad escolar diagnóstico PCI clasificación funcional motora gruesa grados i al iii clasificación topográfica de hemiparesia con puntaje 0 a 2 escala tardieu. Resultados: Realizamos una valoración inicial y final se aplicaron 10 sesiones de terapia con el uso de la consola wii y el software wii Sports en juegos de baseball y box durante 20 minutos por sesión. Se realizó una evaluación final y análisis estadístico de los resultados con el paquete SPSS bajo un nivel de confianza de 95% con las pruebas de chi cuadrado y de Friedman con el coeficiente de concordancia de Kendall obtuvimos