International Journal of Gynecology & Obstetrics 119S3 (2012) S261–S530
Contents lists available at SciVerse ScienceDirect
International Journal of Gynecology and Obstetrics j o u r n a l h o m e p a g e : w w w. e l s ev i e r. c o m / l o c a t e / i j g o
Free communication (oral) presentations Abstracts in this section appear in alphabetical order according to presenter’s name, as per September 25, 2012 O001 THE EFFECT OF PREOPERATIVE SINGLE-DOSE METHYLPREDNISOLONE ON POSTOPERATIVE REHABILITATION AFTER ABDOMINAL HYSTERECTOMY: A RANDOMIZED CONTROLLED TRIAL A.J.M. Aabakke1 , L.B. Holst2 , J.C. Jørgensen1 , N.J. Secher3 . 1 Department of Obstetrics and Gynaecology, University of Copenhagen, Holbæk Hospital, Holbæk, Denmark; 2 Department of Anaesthesiology, University of Copenhagen, Holbæk Hospital, Holbæk, Denmark; 3 Department of Obstetrics and Gynaecology,University of Copenhagen, Hvidovre Hospital, Hvidovre, Denmark
O002 PSYCHOLOGICAL DISTRESS IN OLDER FIRST TIME MOTHERS, FROM MID-PREGNANCY TO 18 MONTHS AFTER BIRTH V. Aasheim1,2 , A. Hjelmstedt1 , H.J. Pettersson4 , S. Rasmussen3 , U. Waldenstrom1 , E. Schytt1 . 1 Karolinska Institutet, Department of Women’s and Children’s Health, Stockholm, Sweden; 2 Centre for Evidence-Based Practice, Bergen University College, Bergen, Norway; 3 Institute of Clinical Medicine, Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway; 4 Karolinska Institutet, Institutionen f¨ or klinisk forskning och utbildning, Stockholm, Sweden
Objectives: To compare the effect of 125mg Methylprednisolone (MP) with placebo on the postoperative rehabilitation after abdominal hysterectomy. Materials: Elective abdominal hysterectomies (n = 62) were randomized to receive either 125mg MP (n = 33) or saline (n = 29) i.v. preoperatively at a Danish university hospital. Methods: Randomization was computer-generated, with allocation concealment by opaque sequentially numbered sealed envelopes. Primary outcome was pain measured on a visual analogue scale (VAS) ranging from 0.0 (no pain) to 10.0 (worst pain) and assessed at rest and during mobilization repeatedly the first 24 hours and daily 2–7 days postoperatively. Pain scores were controlled for surgeon experience and surgery type in the statistical analysis. Secondary outcomes were postoperative use of opioids and antiemetics, vomiting, C-reactive protein (CRP) concentrations and time to mobilization and discharge. Participants, surgeons and outcome assessors were blinded to group assignment. Results: 49 woman were included in the analysis (MP n = 25, saline n = 24). Pain scores controlled for surgeon experience and surgery type did not differ between the two groups at rest (0.60 [95% CI -0.01–1.21] p = 0.055) but during mobilization VAS-scores were significantly higher in the MP group (0.89 [95% CI 0.11–1.64] p = 0.026). Both at rest and during mobilization VAS-scores were significantly lower when the surgeon performing the hysterectomy had at least 5 years experience as a gynaecological senior surgeon (rest 0.83 [95% CI 0.18–1.47] p = 0.012; mobilization 1.00 [95% CI 0.19–1.81] p = 0.016). At mobilization VAS-scores were higher after subtotal than total hysterectomy (0.95 [95% CI 0.16–1.74] p = 0.019). There was no difference between the MP and saline group regarding cumulated use of opioids (p = 0.241), antiemetics (p = 0.142) and number of vomits (p = 0.260) 24 hours postoperatively and time to mobilization (p = 0.238) and discharge (p = 0.276). CRP levels were significantly higher in the placebo group (p = 0.012). Conclusions: This study showed no beneficial effect of preoperative MP on postoperative pain or rehabilitation after abdominal hysterectomy. MP significantly lowered postoperative CRP concentrations. Based on this study a preoperative singledose administration of glucocorticoid seems to have no effect on postoperative pain and rehabilitation after abdominal hysterectomy. Trial Registration ClinicalTrials.gov; Identifier: NCT01106547
Objectives: Maternal age at first childbirth has increased dramatically during the last decades in most high income countries. The postponement of childbearing has been high on the research agenda because of the subsequent increase in medical complications during pregnancy and birth, and also because of its long-term consequences on the total fertility rate. However, there is a gap in knowledge about the psychological well-being of older first time mothers. The objective of this study was to investigate if advanced maternal age at first birth increases the risk of psychological distress, by means of depressive and anxiety symptoms, from mid-pregnancy to 18 months after the birth. Materials: 19,291 nulliparous, Norwegian speaking women, were reqruited between 1999 and 2009 from all hospitals and maternity units with more than 100 births annually. Methods: Selected data from the Norwegian Mother and Child Cohort Study (MoBa) was used. Data was collected by means of six questionnaires during pregnancy and postpartum. Psychological distress was measured by a short form of the Hopkins Symptom Checklist (SCL5) in pregnancy weeks 17 and 30 and 6 months and 18 months post-partum. Advanced maternal age was defined as ≥32 years and a reference group of women 25–31 years was used for comparisons. Women aged 20–24 years were also included. The prevalence of psychological distress at three time points was estimated and generalized estimation equations were used to investigate associations between advanced maternal age and psychological distress. Results: The findings will be presented at the conference. Conclusions: The conclusion will be presented at the conference O003 MACROSOMIA: A MOROCCAN TEACHING HOSPITAL STUDY ABOUT 1335 CASES S. Abakka1 , N. Khoummane1 , A. Ansari Chenguiti1 , S. Amrani1 , S. Bargach1 . 1 Obstetrics and gynaecology, oncology and high risk pregnancies, Maternity hospital Souissi, Rabat, Rabat-Sal´e, Morocco Objectives: Our aim was to determine the prevalence of macrosomia in 2011, its risk factors and morbidity. Materials: We studied the obstetrics notes of all deliveries of newborns with a birthweight of 4000 g and above, from the 1st January 2011 to the 31st Decembre 2011, at the teaching Maternity hospital Souissi of Rabat, Morocco. We also used abstracts and
0020-7292/ $ – see front matter © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
S262
Free communication (oral) presentations / International Journal of Gynecology & Obstetrics 119S3 (2012) S261–S530
articles published in Medline, Sciencedirect and Em-consulte for our research. Methods: We conducted a retrospective study, and the statistical analysis was performed with the SPSS 10.0Results: In 2011, 1335 macrosomic babies were born, with a prevalence of 8.26%. 857 (64.2%) were male, 477 (35.8%) were female. Shoulder dystocia occurred in 16 neonates (1.2%), of which 7 led to a brachial plexus paralysis and one fracture of the humerus. Maternal perineal tears were observed in 84 cases (6.3%) and postpartum haemorrhage in 26 cases (1.9%), of which 1 resulted in a haemostasis hysterectomy. In univariate analysis, significant risk factors for macrosomia were mother age (p < 0.001), parity (p < 0.001), diabetes (p < 0.001), hypertension (p < 0.001). The mode of delivery (normal vaginal, instrumental or caesarian section) was linked to the fetal weight (p < 0.05). After multivariate analysis, parity, diabetes and hypertension were independent risk factors (p < 0.05). Obstetrical complications and mode of delivery were also found to be significantly related to macrosomia (p < 0.05). Conclusions: Macrosomia leads to maternal and neonatal complications. Its management should include active screening for diabetes in pregnancy, to reduce its morbidity. O004 OBSTETRICAL ACUTE RENAL FAILURE: A REVIEW OF CLINICAL OUTCOME AT TERTIARY CARE R.M. Abbasi1 , S. Shaikh1 . 1 LUMHS, Jamshoro, Sindh, Pakistan Objectives: To determine the frequency of pregnancy related to acute renal failure, etiology, maternal and fetal outcome of this preventable complication of pregnancy. Materials: This study was conducted at the Department of Obstetrics and Gynaecology unit II of Liaquat University of Medical and Health sciences Hospital Hyderabad from January, 2011 to December, 2011. Methods: It was descriptive study. A predesigned proforma was used. The clinical history was noted and all underwent a physical and systemic examination. Urine output was recorded. Routine laboratory tests were performed. Foetal and maternal outcome were recorded. Data was analysed using SPSS. Results: Pregnancy related acute renal failure seen in 56 (1.19%) women. Out of which 15 (27%) were primigravida and 30 (53%) were multigravida. Majority of woman 34 (61%) were between 21–30 years of age. Majority of Woman 41 (73%) patients had not received any antenatal care and there was a history of traditional birth attendants (Dai) assisted home delivery as compared to 15 (27%) cases with adequate antenatal care. Sixteen (29%) women presented in their first trimester of pregnancy while 41 (73%) patients developed acute renal failure in their third trimester or in puerperium and 36 (64%) were anuric. Blood loss due to antepartum and postpartum haemorrhage was the common cause of acute renal failure. Clinical spectrum of pregnancy related to acute renal failure showed antepartum haemorrhage 18 (32%) cases, postpartum haemorrhage in 5 (9%) cases, eclampsia in 11 (20%) cases and septicemia seen in 12 (21%) cases. Twenty four (43%) women receive haemodialysis and 32 (57%) did not received dialysis. Maternal mortality was 26 (46%) while foetal loss was 36 (64%). Conclusions: Obstetrical acute renal failure is not only a major health problem but it also leads to high maternal and perinatal mortality
O005 HEALTH PROMOTION FOR WOMEN WITH FEMALE GENITAL MUTILATION/ CUTTING (FGM/C) J. Abdulcadir1 , C. Margairaz2 , M. Boulvain3 , O. Irion3 . 1 Department of Obstetrics and Gynecology. Working Group on FGM/C. University Hospitals of Geneva, Geneva, Switzerland; 2 Department of Community Medicine and Primary Care. Working Group on FGM/C. University Hospitals of Geneva, Geneva, Switzerland; 3 Department of Obstetrics and Gynecology. University Hospitals of Geneva, Geneva, Switzerland Objectives: To improve the health care of FGM/C patients and promote FGM/C prevention regarding their daughters. The aim of this abstract is to present our data. Materials: In a multi-ethnic society, Western gynecologists and obstetricians have to be prepared to face women originating from countries where FGM/C are ritually performed. Recent studies emphasize the lack of knowledge about the management of these women. Nevertheless, they can have different needs and require specific cultural as well as medical skills in order to offer a good diagnostic, therapeutic and preventive approach. A specific and multidisciplinary clinic for caring of women with FGM/C has been implemented at the Department of Obstetrics and Gynecology of the Geneva University Hospitals since April 2010Methods: Analysis of data of our clinic for women with FGM/CResults: During the first year (April 2010-April 2011), 74 patients attended the clinic. The average age was 30 years. They were mainly married (55 patients, 74%). They predominantly originated from Eritrea (25 patients; 34%), Somalia (21 patients; 28%), and Sudan (6 patients; 8%). Type III FGM/C (57 patients; 77%) was the most frequent type, followed by type II (9 patients; 12.2%). Consultation purposes were: information, counseling during pregnancy regarding the delivery management (eg. Intrapartum defibulation, dealing with demands of reinfibulation, which is not performed in our Department); post partum examination and prevention of FGM/C in case of baby girls; demands of defibulation or anatomical restoration (1 clitoral reconstruction until now), care and surgery in case of long term complications (epidermal cysts and one case of clitoral neuroma). Many of our patients attended the clinic to obtain simply clear information about their mutilation. In April 2012 we will add the results of the 2nd year of work. Conclusions: Women with FGM/C often have specific psychological and physical needs, associated with their personal experience of circumcision, migration and life events. A multidisciplinary team including a specifically trained gynecologist and the collaboration with pediatricians, psychiatrics-sexologists, midwives, forensic scientists and interpreters can improve the quality of prevention and health care. Offering a specifically adapted medical care improves trust, compliance and health promotion of women with FGM/C not only in terms of eventual specific complications but also in terms of women’s health (gynecological screenings, sexual health, contraception etc.) O006 FEMALE GENITAL MUTILATION (FGM): A COMPARISON BETWEEN THE MALE AND THE FEMALE VIEW O. Abdulcadir1,2 , L. Catania2 , A. Caselli2 . 1 Careggi University Hospital, Florence, Italy; 2 Reference Center for FGM, Florence, Italy Objectives: The aim of this research is to analyze the role of the men in the practice of FGM and to compare it with the role of the women. The study, patrocinated by the region Tuscany, promoted discussion about FGM in those groups of immigrants where FGM is still practiced in order to understand the different meaning of FGM given by the male groups and the female groups so that effective preventive actions could be taken. Materials: Focus Groups, were organised to make men and women discuss about the topic. The discussions were audio recorded and then transcripted to find the main discussion themes.