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eclampsia in pregnant women
Free communication (oral) presentations / International Journal of Gynecology & Obstetrics 107S2 (2009) S93–S396
2006. Squamous cell carcinoma was the most common histological subtype, accounting for 79% of all cancer cases. Conclusion: We found an increase in the incidence of anal cancer among women in Denmark. As most anal cancers are associated with HPV16 and HPV18, the HPV vaccines may be valuable instruments in the future prevention of anal cancer. O676 Safety of medical vs. surgical abortion in adolescents M. Niinimaki ¨ 1 , A. Pouta2 , A. Bloigu2 , M. Gissler3 , E. Hemminki3 , S. Suhonen4 , O. Heikinheimo4 . 1 Departement of Obstetrics and Gynecology, University Hospital of Oulu, Finland, 2 National Institute for Health and Welfare, Oulu, Finland, 3 National Institute for Health and Welfare, Helsinki, Finland, 4 The Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland Objectives: Safe abortion is an important public health issue. We investigated the immediate (<42 days) post-abortal adverse events following medical vs. surgical abortion among adolescent women using Finnish national health registries. Materials and Methods: The study consists of 2 454 medical and 2 234 surgical abortions among women <18 years of age, and 19 914 medical abortions among women aged ≥18 years. The duration of gestation was ≤63 days. Results: Majority of the adolescents in medical (84%) and surgical (95%) group did not have any adverse events. More cases of haemorrhage (13% vs. 1.5%, p < 0.001), incomplete abortions (3.4 vs. 1.7%, p < 0.001) and surgical re-evacuation (3.0% vs. 1.6%, p = 0.002) were noticed after medical abortion. The incidence of infections (1.4% vs. 1.5%, p = 0.79) did not differ between the groups. Surgical injury or complication requiring surgical intervention was more common after surgical abortion (0.36% vs. 0.04%, p = 0.01). No difference in the incidence of thromboembolic events and psychiatric morbidity were noticed between the cohorts. No pregnancy-related deaths occurred in this cohort. When compared to adults, the incidence of haemorrhage (p = 0.001), incomplete abortion (p < 0.001), surgical (re)evacuation (p < 0.001) and number of complications (p < 0.001) were significantly lower in adolescent cohort following both methods. The incidence of infections, injuries or surgical interventions, thromboembolic disease and psychiatric morbidity did not differ between adolescents and adults. Conclusions: The incidence of post-abortal complications is similar or lower among adolescents than among adult women. Compared to surgical method, medical abortion is a safe alternative to adolescent women. O677 Does Ljungan virus cause malformation, intrauterine fetal death and sudden infant death syndrome? B. Niklasson1 , A. Samsioe2 , P. Rasten Almqvist3 , N. Papadogiannakis4 , W. Klitz5 . 1 Department of Medical Cell Biology, Uppsala University, Box 571, SE-751 23, 2 Division of Reproductive and Perinatal Health, Department of Woman and Child Health Karolinska Institutet, Retzius v¨ ag 13 A, SE-171 77 Stockholm, 3 National Board of Forensic Medicine in Stockholm, 171 65 Solna, Sweden, 4 Department of Pathology, Karolinska University Hospital, Huddinge, SE-141 86 Stockholm, Sweden, 5 School of Public Health, University of California, 50 University Hall, Berkeley, CA and Public Health Institute, Oakland, CA, USA Objectives: The Ljungan virus (LV), a member of the Parecho virus genus, and Picornaviridae family, was originally isolated from its wild reservoir, the bank vole (Myodes glareolus), at the Ljungan River in central Sweden. Ljungan virus is associated with diseases such as myocarditis, encephalitis, pregnancy-related diseases and diabetes in several species of wild rodents. The same outcomes can be induced in CD-1 mice under controlled laboratory conditions. The present study investigates whether malformation, intrauterine
S287
fetal death (IUFD) and sudden infant death syndrome (SIDS) in humans may have Ljungan virus as a common zoonotic etiology. Methods: Formalin fixed tissues from IUFD, SIDS and hydrocephalus cases were investigated using LV specific immunohistochemistry (IHC). Tissues from elective abortions due to Trisomia 21 were used as controls. Frozen specimens were analyzed for presence of LV specific RNA using a real time RT PCR. Results: Ljungan virus was detected by IHC in the majority of IUFD (7/16), SIDS (6/8) and hydrocephalus (9/10) cases while only one of eighteen Trisomia 21 control cases investigated by IHC. The IHC results have been confirmed by RT PCR. O678 Relationship of vitamin E consumption and preeclampsia/eclampsia in pregnant women S. Nikpour1 , Z. Atarodi kashany2 , S. Parsay1 , H. Haghani3 . 1 Public health nursing School of Nursing and Midwifery and Center for Nursing Care Research, 2 Midwifery, 3 Statistics Pregnancy influencing the health of mothers and their fetus. So, prevention of these complications through Providing mothers with natural diet vitamins during pregnancy is very important. Material and Method: This was a case–control study. data were collected through interview and filling up questionnaires. One hundred and fifty four with age between 18–35 years were selected through continues sampling method (75 women in case and 79 in control group). Case and control groups were matched according to the gravida and vitamins supplement consumption. Results: Finding indicated that there were statistically significant relationship between preeclampsia/eclampsia and consumption of foods rich in vitamin E. This relationship was significant according to the number of servings and also amount of vitamin E received, for the number of serving for both nuts and unsaturated vegetable oil (P = 0/000), mayonnaise cream (P = 0/012), and for the amount of vitamin E received from diet (≥15 mg/day) (P = 0/000). Consumption of these diets in case group was less than control group. The consumption of saturated vegetable oil in case group were higher than control group (P = 0/009). Conclusion: As the results showed, there were direct relations between preeclampsia/eclampsia and insufficient consumption of food full of vitamin E.proper educational programs about nutrition during pregnancy, particularly during first trimester in first pregnancy, is recommended. prospective studies are suggested in order to confirm the existed findings. O679 Vaginoplasty using amnion graft: Revisited P. Nisa, I. Sarwar. Ayub Teaching Hospital, Abbottabad Objectives: The aim of this study was to determine the effectiveness of vaginoplasty by using amnion graft in the creation of neovagina for patients with vaginal agenesis. Material and Methods: This is a retrospective study of 28 cases of vaginal agenesis associated with Mayer-Rokitansky-Kuster-Hauser syndrome, over a period of 15 years presenting in the department of gynaecology and obstetrics, Ayub Teaching Hospital, Abbottabad. In all cases vaginoplasty was performed by using amnion as graft. Results: Vaginoplasty using amnion as graft was performed in all cases except one in which rectum got opened and procedure was abandoned after repair of the rectum. The functional results were quite satisfactory. Except one case none had any significant peri operative complications. None of the patients had vaginal stenosis during follow up visits. Post surgical results were acceptable to the patients sexually and aesthetically. Conclusions: Although new techniques of vaginoplasty have evolved over the years using different graft materials and laparoscopy, but in the developing country like Pakistan where facilities and expertise for newer techniques are not available freely, vaginoplasty with amnion graft is still a safe, effective and cheap
2006. Squamous cell carcinoma was the most common histological subtype, accounting for 79% of all cancer cases. Conclusion: We found an increase in the incidence of anal cancer among women in Denmark. As most anal cancers are associated with HPV16 and HPV18, the HPV vaccines may be valuable instruments in the future prevention of anal cancer. O676 Safety of medical vs. surgical abortion in adolescents M. Niinimaki ¨ 1 , A. Pouta2 , A. Bloigu2 , M. Gissler3 , E. Hemminki3 , S. Suhonen4 , O. Heikinheimo4 . 1 Departement of Obstetrics and Gynecology, University Hospital of Oulu, Finland, 2 National Institute for Health and Welfare, Oulu, Finland, 3 National Institute for Health and Welfare, Helsinki, Finland, 4 The Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, Finland Objectives: Safe abortion is an important public health issue. We investigated the immediate (<42 days) post-abortal adverse events following medical vs. surgical abortion among adolescent women using Finnish national health registries. Materials and Methods: The study consists of 2 454 medical and 2 234 surgical abortions among women <18 years of age, and 19 914 medical abortions among women aged ≥18 years. The duration of gestation was ≤63 days. Results: Majority of the adolescents in medical (84%) and surgical (95%) group did not have any adverse events. More cases of haemorrhage (13% vs. 1.5%, p < 0.001), incomplete abortions (3.4 vs. 1.7%, p < 0.001) and surgical re-evacuation (3.0% vs. 1.6%, p = 0.002) were noticed after medical abortion. The incidence of infections (1.4% vs. 1.5%, p = 0.79) did not differ between the groups. Surgical injury or complication requiring surgical intervention was more common after surgical abortion (0.36% vs. 0.04%, p = 0.01). No difference in the incidence of thromboembolic events and psychiatric morbidity were noticed between the cohorts. No pregnancy-related deaths occurred in this cohort. When compared to adults, the incidence of haemorrhage (p = 0.001), incomplete abortion (p < 0.001), surgical (re)evacuation (p < 0.001) and number of complications (p < 0.001) were significantly lower in adolescent cohort following both methods. The incidence of infections, injuries or surgical interventions, thromboembolic disease and psychiatric morbidity did not differ between adolescents and adults. Conclusions: The incidence of post-abortal complications is similar or lower among adolescents than among adult women. Compared to surgical method, medical abortion is a safe alternative to adolescent women. O677 Does Ljungan virus cause malformation, intrauterine fetal death and sudden infant death syndrome? B. Niklasson1 , A. Samsioe2 , P. Rasten Almqvist3 , N. Papadogiannakis4 , W. Klitz5 . 1 Department of Medical Cell Biology, Uppsala University, Box 571, SE-751 23, 2 Division of Reproductive and Perinatal Health, Department of Woman and Child Health Karolinska Institutet, Retzius v¨ ag 13 A, SE-171 77 Stockholm, 3 National Board of Forensic Medicine in Stockholm, 171 65 Solna, Sweden, 4 Department of Pathology, Karolinska University Hospital, Huddinge, SE-141 86 Stockholm, Sweden, 5 School of Public Health, University of California, 50 University Hall, Berkeley, CA and Public Health Institute, Oakland, CA, USA Objectives: The Ljungan virus (LV), a member of the Parecho virus genus, and Picornaviridae family, was originally isolated from its wild reservoir, the bank vole (Myodes glareolus), at the Ljungan River in central Sweden. Ljungan virus is associated with diseases such as myocarditis, encephalitis, pregnancy-related diseases and diabetes in several species of wild rodents. The same outcomes can be induced in CD-1 mice under controlled laboratory conditions. The present study investigates whether malformation, intrauterine
S287
fetal death (IUFD) and sudden infant death syndrome (SIDS) in humans may have Ljungan virus as a common zoonotic etiology. Methods: Formalin fixed tissues from IUFD, SIDS and hydrocephalus cases were investigated using LV specific immunohistochemistry (IHC). Tissues from elective abortions due to Trisomia 21 were used as controls. Frozen specimens were analyzed for presence of LV specific RNA using a real time RT PCR. Results: Ljungan virus was detected by IHC in the majority of IUFD (7/16), SIDS (6/8) and hydrocephalus (9/10) cases while only one of eighteen Trisomia 21 control cases investigated by IHC. The IHC results have been confirmed by RT PCR. O678 Relationship of vitamin E consumption and preeclampsia/eclampsia in pregnant women S. Nikpour1 , Z. Atarodi kashany2 , S. Parsay1 , H. Haghani3 . 1 Public health nursing School of Nursing and Midwifery and Center for Nursing Care Research, 2 Midwifery, 3 Statistics Pregnancy influencing the health of mothers and their fetus. So, prevention of these complications through Providing mothers with natural diet vitamins during pregnancy is very important. Material and Method: This was a case–control study. data were collected through interview and filling up questionnaires. One hundred and fifty four with age between 18–35 years were selected through continues sampling method (75 women in case and 79 in control group). Case and control groups were matched according to the gravida and vitamins supplement consumption. Results: Finding indicated that there were statistically significant relationship between preeclampsia/eclampsia and consumption of foods rich in vitamin E. This relationship was significant according to the number of servings and also amount of vitamin E received, for the number of serving for both nuts and unsaturated vegetable oil (P = 0/000), mayonnaise cream (P = 0/012), and for the amount of vitamin E received from diet (≥15 mg/day) (P = 0/000). Consumption of these diets in case group was less than control group. The consumption of saturated vegetable oil in case group were higher than control group (P = 0/009). Conclusion: As the results showed, there were direct relations between preeclampsia/eclampsia and insufficient consumption of food full of vitamin E.proper educational programs about nutrition during pregnancy, particularly during first trimester in first pregnancy, is recommended. prospective studies are suggested in order to confirm the existed findings. O679 Vaginoplasty using amnion graft: Revisited P. Nisa, I. Sarwar. Ayub Teaching Hospital, Abbottabad Objectives: The aim of this study was to determine the effectiveness of vaginoplasty by using amnion graft in the creation of neovagina for patients with vaginal agenesis. Material and Methods: This is a retrospective study of 28 cases of vaginal agenesis associated with Mayer-Rokitansky-Kuster-Hauser syndrome, over a period of 15 years presenting in the department of gynaecology and obstetrics, Ayub Teaching Hospital, Abbottabad. In all cases vaginoplasty was performed by using amnion as graft. Results: Vaginoplasty using amnion as graft was performed in all cases except one in which rectum got opened and procedure was abandoned after repair of the rectum. The functional results were quite satisfactory. Except one case none had any significant peri operative complications. None of the patients had vaginal stenosis during follow up visits. Post surgical results were acceptable to the patients sexually and aesthetically. Conclusions: Although new techniques of vaginoplasty have evolved over the years using different graft materials and laparoscopy, but in the developing country like Pakistan where facilities and expertise for newer techniques are not available freely, vaginoplasty with amnion graft is still a safe, effective and cheap