- Email: [email protected]
OMISSION
N E W S
Continued from page 556 Yorba Linda, Calif.; Sumita B. Mitra, Ph.D., 3M ESPE Dental Products Laboratory, St. Paul, Minn. dADA representatives: Laura A. Kosden, publisher and chief operating officer, ADA Publishing, ADA Business Enterprises Inc., Chicago; James H. Berry, associate publisher, editorial, ADA Publishing; and James Sandrik, Ph.D., assistant to associate executive director, ADA Division of Science. —Reported by Judy Jakush, editor, ADA News.
GINGIVAL OVERGROWTH GENE DISCOVERED
gene involved in gingival overgrowth has been found by scientists supported by the National Institute of Dental and Craniofacial Research. In an article in the April issue of the American Journal of Human Genetics, scientists report that they have identified the first gene that, when altered, triggers hereditary gingival fibromatosis, or HFG, a
A
MEETINGS
dThe American Association of Women Dentists will hold its 81st Annual Conference June 6-9 in Orlando, Fla. For more information, contact Sharon Gautschy by phone at 1-312280-9296, by fax at 1-312-2809893 or by e-mail at “[email protected]”. dThe American Dental Society of Europe will hold its 108th Meeting June 18-21 in Prague, Czech Republic. For more information, contact Dr. Paul O’Neilly by phone at 011-44-1483-72-84-11, by fax at
560
rare, inherited gingival condition. The SOS1 gene encodes a protein that is known to activate the “ras” pathway, one of the key growth signals in human cells. The study’s authors say this finding suggests that when the SOS1 gene is not mutated, its protein and the ras pathway probably are involved in the normal growth of healthy gingiva, an idea that previously was unknown. If this finding is confirmed, learning how to turn on relevant portions of the pathway, like flipping a biological switch, one day might help dentists regenerate gingivae in people who have receding gingivae or advanced periodontal disease. By switching off the growth signal, dentists could prevent gingival overgrowth; people who have HGF might not need to have the excess issue surgically removed. “By identifying a gene involved in HGF, it was possible to uncover a key clue to normal gingival development, a clue that could have important
implications for dentistry,” said Dr. Thomas C. Hart, lead author of the study.
011-44-1483-72-84-11 or visit “www.adse.co.uk”. dThe American Dental Assistants Association will hold its annual conference July 4-7 in Honolulu. For more information, contact Tina Grikmanis by phone at 1-312-541-1550, by fax at 1-312-541-1496 or by e-mail at “[email protected]”. dThe American College of Dentists will hold its summer conference July 18-21 in Ponte Vedra Beach, Fla. For more information, contact Dr. Stephen Ralls by phone at 1-301-977-3223, by fax at
1-301-977-3330 or by e-mail at “[email protected]”. dThe National Dental Association will hold its 89th Annual Convention July 26-31 in Dallas. For more information, contact LaVette Henderson by phone at 1-202-588-1697, by fax at 1-202-588-1244 or by e-mail at “[email protected]”. dThe South African Dental Association will hold IDEC 2002, an international dental exhibition and congress, Aug. 18-23 in Durban. For more information, contact Dr. Neil
OMISSION
here was an accidental omission from the March JADA column by Dr. Gordon Christensen, “Orthodontics and the General Practitioner.” The sentence that begins on the bottom of page 370 should read, “It is suggested that the procedure cost should be similar to that of conventional orthodontic therapy, but the cost may be higher.”
T
CORRECTION
n article in March JADA, “Screening for Traditional Risk Factors for Cardiovascular Disease: A Review for Oral Health Care Providers” by Michael Glick, D.M.D., contained an error. Under the subhead “Excess body weight” on page 297, the second sentence should read thus: “(The BMI is calculated by dividing the weight in kilograms by the height in square meters.)”
A
Compiled by Amy E. Lund, editorial coordinator.
JADA, Vol. 133, May 2002 Copyright ©2002 American Dental Association. All rights reserved.
Continued from page 556 Yorba Linda, Calif.; Sumita B. Mitra, Ph.D., 3M ESPE Dental Products Laboratory, St. Paul, Minn. dADA representatives: Laura A. Kosden, publisher and chief operating officer, ADA Publishing, ADA Business Enterprises Inc., Chicago; James H. Berry, associate publisher, editorial, ADA Publishing; and James Sandrik, Ph.D., assistant to associate executive director, ADA Division of Science. —Reported by Judy Jakush, editor, ADA News.
GINGIVAL OVERGROWTH GENE DISCOVERED
gene involved in gingival overgrowth has been found by scientists supported by the National Institute of Dental and Craniofacial Research. In an article in the April issue of the American Journal of Human Genetics, scientists report that they have identified the first gene that, when altered, triggers hereditary gingival fibromatosis, or HFG, a
A
MEETINGS
dThe American Association of Women Dentists will hold its 81st Annual Conference June 6-9 in Orlando, Fla. For more information, contact Sharon Gautschy by phone at 1-312280-9296, by fax at 1-312-2809893 or by e-mail at “[email protected]”. dThe American Dental Society of Europe will hold its 108th Meeting June 18-21 in Prague, Czech Republic. For more information, contact Dr. Paul O’Neilly by phone at 011-44-1483-72-84-11, by fax at
560
rare, inherited gingival condition. The SOS1 gene encodes a protein that is known to activate the “ras” pathway, one of the key growth signals in human cells. The study’s authors say this finding suggests that when the SOS1 gene is not mutated, its protein and the ras pathway probably are involved in the normal growth of healthy gingiva, an idea that previously was unknown. If this finding is confirmed, learning how to turn on relevant portions of the pathway, like flipping a biological switch, one day might help dentists regenerate gingivae in people who have receding gingivae or advanced periodontal disease. By switching off the growth signal, dentists could prevent gingival overgrowth; people who have HGF might not need to have the excess issue surgically removed. “By identifying a gene involved in HGF, it was possible to uncover a key clue to normal gingival development, a clue that could have important
implications for dentistry,” said Dr. Thomas C. Hart, lead author of the study.
011-44-1483-72-84-11 or visit “www.adse.co.uk”. dThe American Dental Assistants Association will hold its annual conference July 4-7 in Honolulu. For more information, contact Tina Grikmanis by phone at 1-312-541-1550, by fax at 1-312-541-1496 or by e-mail at “[email protected]”. dThe American College of Dentists will hold its summer conference July 18-21 in Ponte Vedra Beach, Fla. For more information, contact Dr. Stephen Ralls by phone at 1-301-977-3223, by fax at
1-301-977-3330 or by e-mail at “[email protected]”. dThe National Dental Association will hold its 89th Annual Convention July 26-31 in Dallas. For more information, contact LaVette Henderson by phone at 1-202-588-1697, by fax at 1-202-588-1244 or by e-mail at “[email protected]”. dThe South African Dental Association will hold IDEC 2002, an international dental exhibition and congress, Aug. 18-23 in Durban. For more information, contact Dr. Neil
OMISSION
here was an accidental omission from the March JADA column by Dr. Gordon Christensen, “Orthodontics and the General Practitioner.” The sentence that begins on the bottom of page 370 should read, “It is suggested that the procedure cost should be similar to that of conventional orthodontic therapy, but the cost may be higher.”
T
CORRECTION
n article in March JADA, “Screening for Traditional Risk Factors for Cardiovascular Disease: A Review for Oral Health Care Providers” by Michael Glick, D.M.D., contained an error. Under the subhead “Excess body weight” on page 297, the second sentence should read thus: “(The BMI is calculated by dividing the weight in kilograms by the height in square meters.)”
A
Compiled by Amy E. Lund, editorial coordinator.
JADA, Vol. 133, May 2002 Copyright ©2002 American Dental Association. All rights reserved.