ORAL MANIFESTATIONS OF THE COWDEN SYNDROME: CASE REPORT

ORAL MANIFESTATIONS OF THE COWDEN SYNDROME: CASE REPORT

OOOO Volume 129, Number 1 Case 2: A 68-year-old woman showed multiple pigmented lesions on the tongue. Clinical hypotheses were Peutz-Jeghers syndrome...

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OOOO Volume 129, Number 1 Case 2: A 68-year-old woman showed multiple pigmented lesions on the tongue. Clinical hypotheses were Peutz-Jeghers syndrome and Laugier-Hunziker syndrome. Medical investigation revealed chronic abdominal pain history, gastrointestinal bleeding, and previous surgery for excision of polyps. In addition, multiple pigmented skin lesions were detected except on the nails, leading to the final diagnosis of Peutz-Jeghers Syndrome. Both patients remain under follow-up.

TREATMENT OF ODONTOGENIC KERATOCYST USING DECOMPRESSIVE TECHNIQUES, FOLLOWED BY ENUCLEATION CASE REPORT. JULIANA MARIANO BERALDO, SOLIMAR DE OLIVEIRA PONTES, MICHELLE BIANCHI  DE MORAES, FERNANDO VAGNER RALDI, FABIO RICARDO LOUREIRO SATO and, RODRIGO DIAS NASCIMENTO A 54-year-old white male patient sought the outpatient clinic in 2015, presenting spontaneous drainage through the gingival sulcus of tooth 47. On radiographic examination, he presented a radiolucent area compatible with cystic lesion related to tooth 48. An incisional biopsy was performed, and the results presented negative puncture. The treatment was extraction of tooth 48 and lesion decompression with fixed obturator installation that subsequently was replaced by a removable acrylic obturator. The histopathologic examination presented the diagnosis of dentigerous cyst, but because of the characteristics of the lesion, there was a suspicion of odontogenic keratocyst. The patient returned in 2017 for follow-up, and new radiolucent area was verified in the same region. The treatment was the enucleation of the lesion under general anesthesia using Carnoys solution, and a new histopathologic examination confirmed the diagnosis of odontogenic keratocyst. The patient has been undergoing follow-up for 12 months without clinical or radiographic signs of recurrence.

ORAL SIGNS IN A PATIENT WITH UNDIAGNOSED ROSAI-DORFMAN DISEASE: A CASE REPORT. FELIPE SOUZA LIMA ALENCAR,  ALVARO CAVALHEIRO SOARES, LUCIANA FERREIRA STAHEL-LAGE and, JOSE ROBERTO DE MENEZES PONTES Rosai-Dorfman disease (RDD) is a rare, nonneoplastic, idiopathic histiocytic proliferation disorder. Massive lymphadenopathy is one of the main clinical findings, although it can occur without nodal involvement, mimicking other conditions and making diagnosis difficult. Oral manifestations are extremely rare. A 65-year-old female patient was attended for evaluation in a stomatology service at a cancer hospital. Physical examination revealed a reddish macule with irregular contour and telangiectasia and a 4-cm, nodular, sessile, well-delimited lesion with normal coloration that softened to palpation. Both lesions were asymptomatic and localized in the hard palate. Furthermore, multiple papular lesions with bluish coloration in the face were observed. An incisional biopsy of both intraoral lesions was performed, and after the histopathologic and immunohistochemical analysis (S100), the diagnosis of RDD was obtained. Therapy was initially instituted with oral prednisone 60 mg/d resulting in significant regression of clinical signs. Currently, the patient is under monthly follow-up in stomatology and hematology services.

ABSTRACTS

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TREATMENT BY ENUCLEATION OF NASOLABIAL CYST - CASE REPORT. JULIANA MARIANO BERALDO, SOLIMAR DE OLIVEIRA PONTES, MICHELLE BIANCHI DE MORAES,  FERNANDO VAGNER RALDI, FABIO RICARDO LOUREIRO SATO and, RODRIGO DIAS NASCIMENTO A 70-year-old black female patient with total edentulism presenting good general health status appeared in the outpatient clinic in 2014, presenting edema in the region of teeth 12 and 13, resulting in elevation of the nose wing and disappearance of the nasal labial sulcus, with evolution of edema for 6 months and transient episodes of symptomatology. Imaging tests did not show intraosseous lesion reinforcing the diagnostic hypothesis of nasolabial cyst. Excisional biopsy of the lesion was then scheduled in an outpatient setting under local anesthesia. After a positive puncture, an incision was made in the vestibule fundus, capsular divulsion, and lesion enucleation. The material was sent for histopathologic examination, which confirmed the presence of limiting epithelium and the diagnostic hypothesis of nasolabial cyst. After 24 months of preservation no signs of lesion recurrence are observed.

ORAL MANIFESTATIONS OF THE COWDEN SYNDROME: CASE REPORT. KATRYNE DA COSTA, LILIAN MACHADO DE SOUZA ALMEIDA, ELIANE PEDRA DIAS, DANIELLE CASTEX CONDE, ADRIANNA MILAGRES, KARIN SOARES GONCALVES ¸ CUNHA and, RAFAELA ELVIRA ROZZADE-MENEZES Cowden syndrome (CS) is an autosomal dominant disease with increased risk of breast, thyroid, and endometrial malignant neoplasms as well as mucocutaneous lesions. A 63-year-old woman with previous diagnosis of CS was referred to our oral diagnostic clinic complaining of a painless nodule on the left buccal mucosa with history of trauma. The patient also had a history of multiple facial trichilemmomas, palmoplantar keratosis, gastrointestinal polyps, hemangioma on the left upper limb, liposarcoma in the inframammary region, abdominal dermatofibrosarcoma protuberans, and follicular adenoma in the thyroid. Oral examination revealed an isolated painless normochromic nodule on the buccal mucosa and multiple painless normochromic papules diffusely distributed on the upper and lower gingiva and alveolar mucosa. The histopathologic analysis revealed fibrous focal hyperplasia of buccal mucosa nodule and fibroepithelial hyperplasia of upper gingiva. The gingival lesions are one of the oral manifestations of CS. The follow-up has been conducted without oral alterations.

DENTAL CARE IN BURNED PATIENT REPORT OF 2 CASES. ANA LUIZA BARBOZA  VIANNA, CESAR WERNECK NOCE DOS  SANTOS, NATHALIA DE ALMEIDA FREIRE, LIDIANE REZENDE, ROBERTA IMPERIAL, LUCAS LOPES PIMENTEL and, BEATRIZ DA ROCHA MIRANDA VENTURI Despite overall advances in treatment, wound infection remains one of the leading causes of morbidity and mortality in patients with severe burn injuries. Burn injury to the face can lead to scarring and contractures that may impair oral