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Oral Mucoceles: A Clinicopathological Review of 100 Cases
ORAL AND MAXILLOFACIAL PATHOLOGY e218 Abstracts GABRIELA BOTELHO MARTINS. UNIVERSIDADE FEDERAL DA BAHIA. This study investigated risk factors for dental caries, dental erosion, and soft tissue injuries in children with gastroesophageal reflux disease (GERD). Study Design: Twenty-one children with GERD (age 3 to 14 years) underwent oral and salivary examinations, and answered a questionnaire about their medical history, oral hygiene, dental erosion, and dietary habits. Caries was determined according to World Health Organization (WHO) criteria and dental erosion by BEWE index. Results: Two children presented dental erosion. Mean DMFT and dmft were 0.86 and 2.1, respectively. Two children showed dried lips, and one had oral aphthous ulcers on soft tissue evaluation. Conclusion: It was not possible to establish associations between GERD and dental erosion, or between GERD and soft tissue injuries. Vomiting and regurgitation episodes in the sample were controlled by the use of medications, lifestyle modifications, and changes in dietary habits, which may explain these results.
PE-439 - ORAL MUCOCELES: A CLINICOPATHOLOGICAL REVIEW OF 100 CASES. VIRGÍNIA DIAS UZÊDA E SILVA, JAMILE GOMES CONCEIÇÃO, CLARISSA ARAÚJO GURGEL, EDUARDO ANTÔNIO GONÇALVES RAMOS, FLÁVIA CALÓ DE AQUINO XAVIER, LUCIANA MARIA PEDREIRA RAMALHO, JEAN NUNES DOS SANTOS. UNIVERSIDADE FEDERAL DA BAHIA. This study described the clinicopathological features of oral mucoceles. Study Design: We retrospectively reviewed the clinical and histopathological data of oral mucoceles diagnosed by the Oral Pathology Service from 2002 to 2010. Results: The average age of the 100 patients chosen was 23.2 years, with a 1.64:1 male-to-female ratio, and predilection for the lower lip (90%). The lesions were often nodules or blisters, of elastic consistency, variable in color, mean size of 1.1 cm, and preceded by trauma. The most common clinical diagnosis was mucocele (84%) or ranula (10%). Solitary (37%), multiple cavity (33%), and noncystic structures were seen (30%) surrounded by chronic (61%) or mixed granulation tissue (29%) adjacent to the salivary gland (81%). Variants with unusual histopathological findings included superficial mucoceles (16%), myxoglobulosis (9%), pseudopapillary projections (3%), epithelioid histiocytes (4%), and multinucleated giant cells (1%). Conclusion: This study provided important insight into the demographic and histopathological features of oral mucoceles.
PE-440 - ORAL PROBLEMS AND TREATMENT NEEDS OF ADULTS AND CHILDREN WITH SICKLE CELL ANEMIA. ALINE CACHATE DE FARIAS, KARTLAND VIEIRA DE LUNA PAIVA, SONIA MARIA SOARES FERREIRA, FERNANDA BRAGA PEIXOTO, KATARINA JUCÁ DE MORAES FERNANDES, AUREA VALERIA DE MELO FRANCO, MATHEUS HENRIQUE ALVES DE LIMA. CENTRO UNIVERSITARIO CESMAC. The oral problems and treatment needs of adults and children with sickle cell anemia were investigated. Study Design: This cross-sectional study was approved by the research ethics committee of the University Center Cesmac and conducted at the Public Blood Center of Alagoas/Brazil. A questionnaire was administered and examinations were performed. Oral conditions were recorded in accordance with the World Health Organization (WHO) evaluation form. Results: A total of 34 children and
OOOO February 2014 12 adults, all of little education and low socioeconomic class, were examined. All of the patients had pallor of the oral mucosa. In 10 children enamel maturation defects were observed. Although malocclusion has been found, the major problems for these patients remain periodontal diseases and dental caries. Dental restoration is the major treatment need. Conclusions: It is important maintain oral health in order to reduce the risks of dental problems when treating these patients.
PE-441 - OSTEOMYELITIS ASSOCIATED WITH FLORID CEMENTO-OSSEOUS DYSPLASIA: FO/UERJ ORAL MEDICINE SERVICE’S CASUISTICS. ANNA PAULA NIGRI, FLÁVIA SOUZA PEREIRA DE JESUS ALMEIDA, NATHÁLIA ALMEIDA, MARIA ELIZA BARBOSA RAMOS, ROSEMIRO DE MENEZES MACIEL, MÔNICA ISRAEL, SARAH APARECIDA ANTERO. UERJ.
This study sought to correlate florid cement-Osseous dysplasia with the development of secondary osteomyelitis. Study Design: A survey of patients diagnosed with florid cemento-osseous dysplasia who were treated between 2005 and 2013 in UERJ’s oral medicine clinic was conducted. Cases in which the condition evolved to acute or chronic osteomyelitis were studied. About 50% evolved to secondary osteomyelitis after surgical intervention, with 28% after a tooth extraction and 7% after curettage. About 85.7% of cases presented purulent fluid associated with swelling and 14% presented only swelling. Results: The number of cases of florid cemento-osseous dysplasia that evolved to secondary osteomyelitis was significant. Nearly half of these cases were associated with infection. Conclusion: We emphasize the role of the dentist in preventing osteomyelitis development in patients with florid cementoosseous dysplasia. Teeth extraction and biopsies must be avoided. Preventive consultations with the dentist are strongly recommended.
PE-442 - PARTICIPATION OF HYPOXIA-INDUCIBLE FACTOR-1ALPHA AND ANGIOGENESIS IN THE CARCINOGENESIS OF TONGUE AND LOWER LIP SQUAMOUS CELL CARCINOMA. DENISE HÉLEN IMACULADA PEREIRA DE OLIVEIRA, ALESSANDRA OLIVEIRA BARRETO, FERNANDO JOSE DE OLIVEIRA NÓBREGA, DMITRY JOSÉ DE SANTANA SARMENTO, MARCELO GADELHA VASCONCELOS, ÉRICKA JANINE DANTAS DA SILVEIRA, LÉLIA MARIA GUEDES QUEIROZ. UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE.
This study analyzed the immunoexpression of HIF-1a and VEGF-C in squamous cell carcinoma (SCC) of the lower lip and tongue, comparing them with the pattern of aggressiveness of these tumors, since they exhibit different biological behaviors. Study Design: Thirty-four cases of lower lip SCC and 32 cases of tongue SCC were subjected to the immunoperoxidase method. The expressions of HIF-1a and VEGF-C were analyzed semiquantitatively. Results: HIF-1a and VEGF were expressed in all specimens. The means of HIF-1a and VEGF-C (p > 0.05) were similar. We detected a higher mean for both HIF-1a and a similar level for VEGF-C in the stroma and parenchyma of tongue SCC where the patient died, but there was no statistically significant association (p > 0.05). Conclusions: Hypoxia and angiogenesis were important events in oral carcinogenesis, but these processes did not reflect the clinical behavior and prognosis of the SCC of the lower lip and tongue studied.
PE-439 - ORAL MUCOCELES: A CLINICOPATHOLOGICAL REVIEW OF 100 CASES. VIRGÍNIA DIAS UZÊDA E SILVA, JAMILE GOMES CONCEIÇÃO, CLARISSA ARAÚJO GURGEL, EDUARDO ANTÔNIO GONÇALVES RAMOS, FLÁVIA CALÓ DE AQUINO XAVIER, LUCIANA MARIA PEDREIRA RAMALHO, JEAN NUNES DOS SANTOS. UNIVERSIDADE FEDERAL DA BAHIA. This study described the clinicopathological features of oral mucoceles. Study Design: We retrospectively reviewed the clinical and histopathological data of oral mucoceles diagnosed by the Oral Pathology Service from 2002 to 2010. Results: The average age of the 100 patients chosen was 23.2 years, with a 1.64:1 male-to-female ratio, and predilection for the lower lip (90%). The lesions were often nodules or blisters, of elastic consistency, variable in color, mean size of 1.1 cm, and preceded by trauma. The most common clinical diagnosis was mucocele (84%) or ranula (10%). Solitary (37%), multiple cavity (33%), and noncystic structures were seen (30%) surrounded by chronic (61%) or mixed granulation tissue (29%) adjacent to the salivary gland (81%). Variants with unusual histopathological findings included superficial mucoceles (16%), myxoglobulosis (9%), pseudopapillary projections (3%), epithelioid histiocytes (4%), and multinucleated giant cells (1%). Conclusion: This study provided important insight into the demographic and histopathological features of oral mucoceles.
PE-440 - ORAL PROBLEMS AND TREATMENT NEEDS OF ADULTS AND CHILDREN WITH SICKLE CELL ANEMIA. ALINE CACHATE DE FARIAS, KARTLAND VIEIRA DE LUNA PAIVA, SONIA MARIA SOARES FERREIRA, FERNANDA BRAGA PEIXOTO, KATARINA JUCÁ DE MORAES FERNANDES, AUREA VALERIA DE MELO FRANCO, MATHEUS HENRIQUE ALVES DE LIMA. CENTRO UNIVERSITARIO CESMAC. The oral problems and treatment needs of adults and children with sickle cell anemia were investigated. Study Design: This cross-sectional study was approved by the research ethics committee of the University Center Cesmac and conducted at the Public Blood Center of Alagoas/Brazil. A questionnaire was administered and examinations were performed. Oral conditions were recorded in accordance with the World Health Organization (WHO) evaluation form. Results: A total of 34 children and
OOOO February 2014 12 adults, all of little education and low socioeconomic class, were examined. All of the patients had pallor of the oral mucosa. In 10 children enamel maturation defects were observed. Although malocclusion has been found, the major problems for these patients remain periodontal diseases and dental caries. Dental restoration is the major treatment need. Conclusions: It is important maintain oral health in order to reduce the risks of dental problems when treating these patients.
PE-441 - OSTEOMYELITIS ASSOCIATED WITH FLORID CEMENTO-OSSEOUS DYSPLASIA: FO/UERJ ORAL MEDICINE SERVICE’S CASUISTICS. ANNA PAULA NIGRI, FLÁVIA SOUZA PEREIRA DE JESUS ALMEIDA, NATHÁLIA ALMEIDA, MARIA ELIZA BARBOSA RAMOS, ROSEMIRO DE MENEZES MACIEL, MÔNICA ISRAEL, SARAH APARECIDA ANTERO. UERJ.
This study sought to correlate florid cement-Osseous dysplasia with the development of secondary osteomyelitis. Study Design: A survey of patients diagnosed with florid cemento-osseous dysplasia who were treated between 2005 and 2013 in UERJ’s oral medicine clinic was conducted. Cases in which the condition evolved to acute or chronic osteomyelitis were studied. About 50% evolved to secondary osteomyelitis after surgical intervention, with 28% after a tooth extraction and 7% after curettage. About 85.7% of cases presented purulent fluid associated with swelling and 14% presented only swelling. Results: The number of cases of florid cemento-osseous dysplasia that evolved to secondary osteomyelitis was significant. Nearly half of these cases were associated with infection. Conclusion: We emphasize the role of the dentist in preventing osteomyelitis development in patients with florid cementoosseous dysplasia. Teeth extraction and biopsies must be avoided. Preventive consultations with the dentist are strongly recommended.
PE-442 - PARTICIPATION OF HYPOXIA-INDUCIBLE FACTOR-1ALPHA AND ANGIOGENESIS IN THE CARCINOGENESIS OF TONGUE AND LOWER LIP SQUAMOUS CELL CARCINOMA. DENISE HÉLEN IMACULADA PEREIRA DE OLIVEIRA, ALESSANDRA OLIVEIRA BARRETO, FERNANDO JOSE DE OLIVEIRA NÓBREGA, DMITRY JOSÉ DE SANTANA SARMENTO, MARCELO GADELHA VASCONCELOS, ÉRICKA JANINE DANTAS DA SILVEIRA, LÉLIA MARIA GUEDES QUEIROZ. UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE.
This study analyzed the immunoexpression of HIF-1a and VEGF-C in squamous cell carcinoma (SCC) of the lower lip and tongue, comparing them with the pattern of aggressiveness of these tumors, since they exhibit different biological behaviors. Study Design: Thirty-four cases of lower lip SCC and 32 cases of tongue SCC were subjected to the immunoperoxidase method. The expressions of HIF-1a and VEGF-C were analyzed semiquantitatively. Results: HIF-1a and VEGF were expressed in all specimens. The means of HIF-1a and VEGF-C (p > 0.05) were similar. We detected a higher mean for both HIF-1a and a similar level for VEGF-C in the stroma and parenchyma of tongue SCC where the patient died, but there was no statistically significant association (p > 0.05). Conclusions: Hypoxia and angiogenesis were important events in oral carcinogenesis, but these processes did not reflect the clinical behavior and prognosis of the SCC of the lower lip and tongue studied.