- Email: [email protected]
P-201: Impact of the frailty status on muscle mass and muscle strength of nursing home residents
Poster presentations / European Geriatric Medicine 6S1 (2015) S32–S156
S85
abductors, hip extensors, elbow extensors and elbow flexors). The Pearson’s correlation test was used to test the relationship between lean mass and muscle strength. Results: The mean values were 9.1±10.1 kg/m2 for ALM/ht2 , 15.9±6.9 kg for grip strength, and for isometric strength they ranged from 56.9±31.5N (elbow extensors) to 101.3±58.2N (knee extensors). Correlation between ALM/ht2 and grip strength was significant (r = 0.28; p = 0.014) as well as between ALM/ht2 and strength of all muscle groups except for hip abductors and extensors. The correlations ranged from 0.38 (elbow extensors and ankle extensors) to 0.52 (elbow extensors). Correlation between lean mass of the dominant leg and grip strength, was also significant (r = 0.44; p = 0.001) whereas the relation between lean mass of the dominant arm and grip strength was not significant (r = 0.19; p = 0.66). Conclusion: There seems to be a positive correlation between appendicular lean mass and strength of various muscle groups including grip strength in nursing home residents. Longitudinal studies are needed to better understand the clinical impact of this observation.
falls in the last year. Frailty was assessed with three different scales: the Fried’s scale, the Frailty Index and the Frailty Trait Scale. And finally, the number of drugs was defined as the number of drug being taken when the interview was done. Logistic regression models were used to assess this relationship using BMI, age and sex as possible confounders. Results: Independently whether the frailty scale is included into the model and the scale used, the number of drugs was associated with RF, OR (95% CI) for an increment of one drug range from 1.085 (1.014–1.160) to 1.087 (1.016–1.163). If we change the order of inclusion in the statistical model, we observed the same effect with the frailty score, OR (95% CI) were 3.800 (2.097–6.901), 1.031(1.015– 1.047) and 1.032 (1.013–1.052) for Frail vs Robust (Fried’s scale) and for an increment of 1 point in the FTS and FI score, respectively. Conclusions: Independently of the frailty scale used, the number of drugs and frailty are two independent risk factors of recurrent falls.
P-201 Impact of the frailty status on muscle mass and muscle strength of nursing home residents
J.J. Calvo Aguirre1 , O. Bueno Yanez ˜ 2 , A. Araneta Herguedas1 , J. Zubeldia Etxeberria1 , N. Zinkunegi Zubizarreta1 , M. Ugartemendia Yerobi1 1 SESOSGI, San Sebastian, Spain; 2 Geriatric Nursing. Residencia Sagrado Coraz´ on, Paseo Gabierrota, Spain
F. Buckinx1 , J.-L. Croisier1 , J.-Y. Reginster1 , J. Petermans1 , O. Bruyere ` 1 1 University of Li`ege, Li`ege, Belgium Background: The aim of this study was to compare muscle mass and muscle strength of frail, pre-frail and robust subjects living in nursing homes. Methods: This is a cross sectional study performed in 10 nursing homes in Liege, ` Belgium. Patients were classified as frail, pre-frail or robust according to Fried’s definition. Muscle mass, and more specifically appendicular lean mass divided by height squared, was assessed using a recently validated bioelectrical impedance analyzer, the InBody S10 (Buckinx et al. 2015). Grip strength was assessed with a hydraulic dynamometer and maximal isometric strength of 8 different muscle groups (i.e. knee extensors, knee flexors, ankle extensors, ankle flexors, hip abductors, hip extensors, elbow flexors and elbow extensors) was assessed with a microFET2 hand-held dynamometer. Results: A total of 250 subjects were included in this study (81.2±10.3 years, 67.2% of women). After adjustment for age, sex and BMI, muscle strength at all sites was significantly different between robust, pre-frail and frail groups. However, the difference in appendicular lean mass was not significant between the three groups based on the frailty status. Conclusion: Frailty status, among nursing home residents, seems to be associated with reduction in muscle strength but not with muscle mass. P-202 Drugs, frailty and falls. The Toledo Study for Healthy Aging ´ Caballero Mora1 , M. Valdes-Aragon M.A. ´ es ´ 2 , F.J. Manzano Lista3 , C. Alonso Bouzon4 , R. Petidier Torregrossa4 1 Hospital Universitario de Getafe, Getafe, Madrid, Spain; 2 Hospital Universitario de Getafe, Madrid, Spain; 3 Hospital Virgen del Valle, Toledo, Spain; 4 Hospital Universitario de Getafe, Getafe, Spain Objectives: Interventions to avoid risk factors associated with frailty are needed among others reduction of drugs to prevent falls. However do not exist studies that analyze the relationship between frailty and drugs. Our objective is to evaluate association between number of drugs and frailty with recurrent falls (RF) in the elderly. Methods: 1723 subjects from the Toledo Study for Healthy Aging, a prospective Spanish cohort study. RF was defined as two or more
P-203 Sarcopenia in elder population with good functional capabilities – Evaluation of functionality and detection
Objectives: The active ageing (WHO) pretends to optimize the health opportunities to improve the elderly population’s life quality. The evaluation of the functional capacity in an elderly population with a good level of basal functionality, allows to detect risk situations and subsidiary sarcopenia improvement, by means of an intervention program. Method: 137 persons were evaluated, all of them with a good level of functionality and autonomous mobility. 103 lived in their community and 34 in residences. Initial evaluation included measurement of anthropometric parameters, history of falls, nutritional and clinic status, polipharmacy, functional status, life quality, MARCHA DUAL, functional status according to Short Physical Performance Battery (SPPB), walking speed, dual walk, muscular strength measured by dynamometry and muscle mass measured by impedanciometry. Sarcopenia diagnosis criteria were established by meeting EWGSOP and Janssen & Masanes criteria. Physical performance status was evaluated by crossedpress strength tests, walking speed and muscle mass index. Results: The average age of the population is 76.6 years (74.6 in the community and 84.3 in the residence). The residential population presents functional tests below the communal. In the communal population, exist 5% of presarcopenia cases and 6% of sarcopenia. In the residential, exist 24% of people with sarcopenia. A physical exercise program is designed for the total population. Conclusions: • Sarcopenia is more frequent in the residential environment than in the communal. • A multicomponent physical exercise program is presented. P-204 The FNIH-criteria for sarcopenia predict 12 year mortality in ambulatory older men S. De Buyser1 , M. Petrovic2 , Y. Taes1 , B. Lapauw1 , K. Toye1 , J.-M. Kaufman1 , S. Goemaere1 1 Ghent University, Ghent, Belgium; 2 Dept. of Geriatrics, Ghent University Hospital, Ghent, Belgium Objectives: The Foundation for the National Institutes of Health [FNIH] Sarcopenia Project recently developed new criteria for diagnosis of weakness and low muscle mass in older adults. These criteria were associated with increased likelihood for
S85
abductors, hip extensors, elbow extensors and elbow flexors). The Pearson’s correlation test was used to test the relationship between lean mass and muscle strength. Results: The mean values were 9.1±10.1 kg/m2 for ALM/ht2 , 15.9±6.9 kg for grip strength, and for isometric strength they ranged from 56.9±31.5N (elbow extensors) to 101.3±58.2N (knee extensors). Correlation between ALM/ht2 and grip strength was significant (r = 0.28; p = 0.014) as well as between ALM/ht2 and strength of all muscle groups except for hip abductors and extensors. The correlations ranged from 0.38 (elbow extensors and ankle extensors) to 0.52 (elbow extensors). Correlation between lean mass of the dominant leg and grip strength, was also significant (r = 0.44; p = 0.001) whereas the relation between lean mass of the dominant arm and grip strength was not significant (r = 0.19; p = 0.66). Conclusion: There seems to be a positive correlation between appendicular lean mass and strength of various muscle groups including grip strength in nursing home residents. Longitudinal studies are needed to better understand the clinical impact of this observation.
falls in the last year. Frailty was assessed with three different scales: the Fried’s scale, the Frailty Index and the Frailty Trait Scale. And finally, the number of drugs was defined as the number of drug being taken when the interview was done. Logistic regression models were used to assess this relationship using BMI, age and sex as possible confounders. Results: Independently whether the frailty scale is included into the model and the scale used, the number of drugs was associated with RF, OR (95% CI) for an increment of one drug range from 1.085 (1.014–1.160) to 1.087 (1.016–1.163). If we change the order of inclusion in the statistical model, we observed the same effect with the frailty score, OR (95% CI) were 3.800 (2.097–6.901), 1.031(1.015– 1.047) and 1.032 (1.013–1.052) for Frail vs Robust (Fried’s scale) and for an increment of 1 point in the FTS and FI score, respectively. Conclusions: Independently of the frailty scale used, the number of drugs and frailty are two independent risk factors of recurrent falls.
P-201 Impact of the frailty status on muscle mass and muscle strength of nursing home residents
J.J. Calvo Aguirre1 , O. Bueno Yanez ˜ 2 , A. Araneta Herguedas1 , J. Zubeldia Etxeberria1 , N. Zinkunegi Zubizarreta1 , M. Ugartemendia Yerobi1 1 SESOSGI, San Sebastian, Spain; 2 Geriatric Nursing. Residencia Sagrado Coraz´ on, Paseo Gabierrota, Spain
F. Buckinx1 , J.-L. Croisier1 , J.-Y. Reginster1 , J. Petermans1 , O. Bruyere ` 1 1 University of Li`ege, Li`ege, Belgium Background: The aim of this study was to compare muscle mass and muscle strength of frail, pre-frail and robust subjects living in nursing homes. Methods: This is a cross sectional study performed in 10 nursing homes in Liege, ` Belgium. Patients were classified as frail, pre-frail or robust according to Fried’s definition. Muscle mass, and more specifically appendicular lean mass divided by height squared, was assessed using a recently validated bioelectrical impedance analyzer, the InBody S10 (Buckinx et al. 2015). Grip strength was assessed with a hydraulic dynamometer and maximal isometric strength of 8 different muscle groups (i.e. knee extensors, knee flexors, ankle extensors, ankle flexors, hip abductors, hip extensors, elbow flexors and elbow extensors) was assessed with a microFET2 hand-held dynamometer. Results: A total of 250 subjects were included in this study (81.2±10.3 years, 67.2% of women). After adjustment for age, sex and BMI, muscle strength at all sites was significantly different between robust, pre-frail and frail groups. However, the difference in appendicular lean mass was not significant between the three groups based on the frailty status. Conclusion: Frailty status, among nursing home residents, seems to be associated with reduction in muscle strength but not with muscle mass. P-202 Drugs, frailty and falls. The Toledo Study for Healthy Aging ´ Caballero Mora1 , M. Valdes-Aragon M.A. ´ es ´ 2 , F.J. Manzano Lista3 , C. Alonso Bouzon4 , R. Petidier Torregrossa4 1 Hospital Universitario de Getafe, Getafe, Madrid, Spain; 2 Hospital Universitario de Getafe, Madrid, Spain; 3 Hospital Virgen del Valle, Toledo, Spain; 4 Hospital Universitario de Getafe, Getafe, Spain Objectives: Interventions to avoid risk factors associated with frailty are needed among others reduction of drugs to prevent falls. However do not exist studies that analyze the relationship between frailty and drugs. Our objective is to evaluate association between number of drugs and frailty with recurrent falls (RF) in the elderly. Methods: 1723 subjects from the Toledo Study for Healthy Aging, a prospective Spanish cohort study. RF was defined as two or more
P-203 Sarcopenia in elder population with good functional capabilities – Evaluation of functionality and detection
Objectives: The active ageing (WHO) pretends to optimize the health opportunities to improve the elderly population’s life quality. The evaluation of the functional capacity in an elderly population with a good level of basal functionality, allows to detect risk situations and subsidiary sarcopenia improvement, by means of an intervention program. Method: 137 persons were evaluated, all of them with a good level of functionality and autonomous mobility. 103 lived in their community and 34 in residences. Initial evaluation included measurement of anthropometric parameters, history of falls, nutritional and clinic status, polipharmacy, functional status, life quality, MARCHA DUAL, functional status according to Short Physical Performance Battery (SPPB), walking speed, dual walk, muscular strength measured by dynamometry and muscle mass measured by impedanciometry. Sarcopenia diagnosis criteria were established by meeting EWGSOP and Janssen & Masanes criteria. Physical performance status was evaluated by crossedpress strength tests, walking speed and muscle mass index. Results: The average age of the population is 76.6 years (74.6 in the community and 84.3 in the residence). The residential population presents functional tests below the communal. In the communal population, exist 5% of presarcopenia cases and 6% of sarcopenia. In the residential, exist 24% of people with sarcopenia. A physical exercise program is designed for the total population. Conclusions: • Sarcopenia is more frequent in the residential environment than in the communal. • A multicomponent physical exercise program is presented. P-204 The FNIH-criteria for sarcopenia predict 12 year mortality in ambulatory older men S. De Buyser1 , M. Petrovic2 , Y. Taes1 , B. Lapauw1 , K. Toye1 , J.-M. Kaufman1 , S. Goemaere1 1 Ghent University, Ghent, Belgium; 2 Dept. of Geriatrics, Ghent University Hospital, Ghent, Belgium Objectives: The Foundation for the National Institutes of Health [FNIH] Sarcopenia Project recently developed new criteria for diagnosis of weakness and low muscle mass in older adults. These criteria were associated with increased likelihood for