- Email: [email protected]
P004 Relationship between blood pressure, body mass and adiposity in populations of different ethnic background
A
1
1
A
19
-
: J
2 9
P
P ANC
CORRELATES
O H V M F S
2
O
D E
E
8
1
W o Depolarization, abnormalities, h~ertension
r
K
C
D AOI
P B M VM mH R J a b
F R U
AI
R M
H S ~, F
P T I K MEN:A PROSPECTIVESTUDY. A Sisni’,G B L R E R E ‘ Medicine, St GeorsQ“S MT P S H,M,S,, London(UK): ‘ C &. Meal, ‘Ocpt oJComnI Meal, Fede?ico11
S n C
AS R i J
J N C c
E
t s
c
h
R B b e
e
h
o
n
a
s
c
r
:
f
O 0 E B
A
E A
C
A
d h
E
I
P O
P
1
Torres,SG Barroso,AVBDuartc,
W
P
;
O o VR
G h t p c r c i e p T t t h s i h n s l c ap r i s s b d n ( a h ( i a t d p w o iT~o t p T h d i O n a t e c w d *2w g e h s a ( + 0 1 * 0 y T i c ( p ( f @ c ( s ( p ( i ( a phmphoms(mS/&y)wers s t e b 2 4 VS 1 1 8 VS 81*9; 3 1 VS 2 4 22VS474*37;3823+237VS3383k452:3276h122VS 3276+364;21*I vs2W52vs 1068+95,respectively. D c a u c r v s h w c H 8 * 6 f m p = a 0 Y 0 0 t 0 p = 0 r T w i a s c c r a d b b u p ( a p=0 T p v f P a c i h t 8 m w 8 a f a d c k 8 m w i!Q~o. e t B p e al e i a p t f t d p i h
K
OH
7
o
P
OF REPOIARIZ4TION ABNORMALITIESIN HYPERTENS1ON. Boyiadzis,E Guzman,A Hernandez,A Armari,and R Cohen, Division of Cardiology, Department of Medicine, Woodhull Medical & Mental Health Center,Brooklyn, NY. Depolarizationabnormalities,a prolonged QTc (PQTc)and a prolongedQTc dispersion (PQTcD) , occur in hypertension(HTN), but their possible relationshipto the severityof arterialpressure n (AP) has not been described in detail, a bas obeen made witbmnormotensive(NT) c p controls. Thus the electrocardiogram(ECG) was examined in 79 consecutivept% (group 1) with untreatedHTN and in 66 NT controls (groupII) Age and sex distributionwas similar in botb groups. The average QTc was 430 * 5 maec in group 1 ve 395 * 2 msec in group (unpairedt test, P
P
2
A
LB
P
A E
P
D C
B W
George’sH.M.S,, L
lDCPIof Medi.ine ‘Oept.fPubli. (UW o
B Y TR A
TI
E t
HealthSc(ences,Sf n
O
d
o
n
UIIiverWYofNqAes(1):‘LkP1ofSCWial&Prev Mcd, SfJN3’IItBqf7i%(I&4). ~ c h i
H
(
m a
( i ~
d
_
m B
7 ( i
W
s a
7 y H
w s S
O m n
a s
s
h
r
k p
p
H m al I (
S h
k 1 P r w w h 1 w d s t b A e b b s w d r d p o 8 ( b H e y ( i c ( h ad p w h h h 9 p H O n ( r e w u w e ( 1 f a ( 1 [ m m as p t t g p
c d
K
w w
m
w O e b A m i m d T h a H d h
o T
w
H
e d
t [ s e
a h
( C L
s t m s
F 4
y m w r e m h v
2
9 H
E
- Hp
s ee 1 > s s t 7 f
a
7
Age, As, WIH Age, &, Bhfl n SBPnunffg SSfPmmHg MEN E 233 132.1(1.4) 131,6(1.4) SA 2S4 134.8(1.3) 133.2(1.3) Af 20S 136,8(1.3) ● 135.5(1.3) ● WOMEN E 291 128,7(1,2) 128.5(1.2) 130.1(1.2) SA 251 131.4(1.2) 135,s (1.0) ● Af 341 134.7(1.0)* SP increasedwifh increasingSMI and W ratio in bth men and wonwn ‘wifhin’ each ethnic group. Multipleregressionmcfftckrm (adjustedfor age, therapy and ethnic group) in men were 0.82(0.18)mmHgSBP@*m’(P-=0.WOI) for BM1and 5.9fl.2) mmHgSBP/O.lunit (P.O.OCOI)for W w significantinteraction y in C (0.95 with BM1and cfhnicify(P4.04) suggesfsfhat the effect is steep-w [0. IO]; in SA (0,60[0.23]; p-O.009) and in Af(O.25[0.19];p-O.19).SimiluI p
s
o
d m
t h 1
R t
d w
T T
s
n ag [
r 1
w [ 1
t s
a
Q
c
p I
o
- Kyi
s
s
y y
b p n
s
i w r
n
m e
n
A~’.for
e m w
&dgfQwL overweight predicts blcod p ( l a m e c differences in the pmvdenw of hypertension around the world. However,it is not clear whelk fhese differencesin f explainedby dif%enccs in obmily and whetherfix relationshipsLk?fween body weight(Wt) and y r estimateOw To adipaity o similarly in these gm.ps. ~ contributionof WI and adiposiw to flP across ethnic gmum and fo comparetk nmanitudeof tk relationshipbstweemmms.res of My maw m BP. A&tUr P c s l m a w l S L ( 4 y of Soufh Asian (SA: n=505), African (Af: ri-549) and E.mpem (whife: n-524) ancestry,randomly sekfed riom general practic&W& height,waist(W)md hip (H) circumferenceswereNken. 8P war meaauredwifhan automatedp=dure. An sdministefcdquestionnaireestablishedethnicityand drug therapy(5x). &@& BP levelswere higher in Af Ibm SA and E (135.O/a7.8w m 2 130.1/85.2 and 127.7/82.0mndig in men; 135.0/84.9.s 127.2179.6and 123.1/77.0H M t rin women). e Thaw differen=s i n groups u & )atir i mmHg in BPh WWween’ remained adjustcrncnt Rx andeifherOMIor W:Hrafia(Table; ●P
p d
r
m eK i
Wet
m t
B d epi d
-oEo
.o - G
nls
c
a
y y o
e
d i
n
r nso
e
iyg
:
1
1
A
19
-
: J
2 9
P
P ANC
CORRELATES
O H V M F S
2
O
D E
E
8
1
W o Depolarization, abnormalities, h~ertension
r
K
C
D AOI
P B M VM mH R J a b
F R U
AI
R M
H S ~, F
P T I K MEN:A PROSPECTIVESTUDY. A Sisni’,G B L R E R E ‘ Medicine, St GeorsQ“S MT P S H,M,S,, London(UK): ‘ C &. Meal, ‘Ocpt oJComnI Meal, Fede?ico11
S n C
AS R i J
J N C c
E
t s
c
h
R B b e
e
h
o
n
a
s
c
r
:
f
O 0 E B
A
E A
C
A
d h
E
I
P O
P
1
Torres,SG Barroso,AVBDuartc,
W
P
;
O o VR
G h t p c r c i e p T t t h s i h n s l c ap r i s s b d n ( a h ( i a t d p w o iT~o t p T h d i O n a t e c w d *2w g e h s a ( + 0 1 * 0 y T i c ( p ( f @ c ( s ( p ( i ( a phmphoms(mS/&y)wers s t e b 2 4 VS 1 1 8 VS 81*9; 3 1 VS 2 4 22VS474*37;3823+237VS3383k452:3276h122VS 3276+364;21*I vs2W52vs 1068+95,respectively. D c a u c r v s h w c H 8 * 6 f m p = a 0 Y 0 0 t 0 p = 0 r T w i a s c c r a d b b u p ( a p=0 T p v f P a c i h t 8 m w 8 a f a d c k 8 m w i!Q~o. e t B p e al e i a p t f t d p i h
K
OH
7
o
P
OF REPOIARIZ4TION ABNORMALITIESIN HYPERTENS1ON. Boyiadzis,E Guzman,A Hernandez,A Armari,and R Cohen, Division of Cardiology, Department of Medicine, Woodhull Medical & Mental Health Center,Brooklyn, NY. Depolarizationabnormalities,a prolonged QTc (PQTc)and a prolongedQTc dispersion (PQTcD) , occur in hypertension(HTN), but their possible relationshipto the severityof arterialpressure n (AP) has not been described in detail, a bas obeen made witbmnormotensive(NT) c p controls. Thus the electrocardiogram(ECG) was examined in 79 consecutivept% (group 1) with untreatedHTN and in 66 NT controls (groupII) Age and sex distributionwas similar in botb groups. The average QTc was 430 * 5 maec in group 1 ve 395 * 2 msec in group (unpairedt test, P
P
2
A
LB
P
A E
P
D C
B W
George’sH.M.S,, L
lDCPIof Medi.ine ‘Oept.fPubli. (UW o
B Y TR A
TI
E t
HealthSc(ences,Sf n
O
d
o
n
UIIiverWYofNqAes(1):‘LkP1ofSCWial&Prev Mcd, SfJN3’IItBqf7i%(I&4). ~ c h i
H
(
m a
( i ~
d
_
m B
7 ( i
W
s a
7 y H
w s S
O m n
a s
s
h
r
k p
p
H m al I (
S h
k 1 P r w w h 1 w d s t b A e b b s w d r d p o 8 ( b H e y ( i c ( h ad p w h h h 9 p H O n ( r e w u w e ( 1 f a ( 1 [ m m as p t t g p
c d
K
w w
m
w O e b A m i m d T h a H d h
o T
w
H
e d
t [ s e
a h
( C L
s t m s
F 4
y m w r e m h v
2
9 H
E
- Hp
s ee 1 > s s t 7 f
a
7
Age, As, WIH Age, &, Bhfl n SBPnunffg SSfPmmHg MEN E 233 132.1(1.4) 131,6(1.4) SA 2S4 134.8(1.3) 133.2(1.3) Af 20S 136,8(1.3) ● 135.5(1.3) ● WOMEN E 291 128,7(1,2) 128.5(1.2) 130.1(1.2) SA 251 131.4(1.2) 135,s (1.0) ● Af 341 134.7(1.0)* SP increasedwifh increasingSMI and W ratio in bth men and wonwn ‘wifhin’ each ethnic group. Multipleregressionmcfftckrm (adjustedfor age, therapy and ethnic group) in men were 0.82(0.18)mmHgSBP@*m’(P-=0.WOI) for BM1and 5.9fl.2) mmHgSBP/O.lunit (P.O.OCOI)for W w significantinteraction y in C (0.95 with BM1and cfhnicify(P4.04) suggesfsfhat the effect is steep-w [0. IO]; in SA (0,60[0.23]; p-O.009) and in Af(O.25[0.19];p-O.19).SimiluI p
s
o
d m
t h 1
R t
d w
T T
s
n ag [
r 1
w [ 1
t s
a
Q
c
p I
o
- Kyi
s
s
y y
b p n
s
i w r
n
m e
n
A~’.for
e m w
&dgfQwL overweight predicts blcod p ( l a m e c differences in the pmvdenw of hypertension around the world. However,it is not clear whelk fhese differencesin f explainedby dif%enccs in obmily and whetherfix relationshipsLk?fween body weight(Wt) and y r estimateOw To adipaity o similarly in these gm.ps. ~ contributionof WI and adiposiw to flP across ethnic gmum and fo comparetk nmanitudeof tk relationshipbstweemmms.res of My maw m BP. A&tUr P c s l m a w l S L ( 4 y of Soufh Asian (SA: n=505), African (Af: ri-549) and E.mpem (whife: n-524) ancestry,randomly sekfed riom general practic&W& height,waist(W)md hip (H) circumferenceswereNken. 8P war meaauredwifhan automatedp=dure. An sdministefcdquestionnaireestablishedethnicityand drug therapy(5x). &@& BP levelswere higher in Af Ibm SA and E (135.O/a7.8w m 2 130.1/85.2 and 127.7/82.0mndig in men; 135.0/84.9.s 127.2179.6and 123.1/77.0H M t rin women). e Thaw differen=s i n groups u & )atir i mmHg in BPh WWween’ remained adjustcrncnt Rx andeifherOMIor W:Hrafia(Table; ●P
p d
r
m eK i
Wet
m t
B d epi d
-oEo
.o - G
nls
c
a
y y o
e
d i
n
r nso
e
iyg
: