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P050 Refined Ventricular Pace Ameliorates Unnecessary Right Ventricular Apical Pacing in Patients with Bradyarrhythmia
Poster Sessions / International Journal of Cardiology 147S1 (2011) S9–S32
Conclusion: This study showed that hypertension was common and an independent predictor of stroke patients in Iran. P049 Epidemiological Survey of Kawasaki Disease in Kurdish Patients in Sanandaj of Iran N. Ghotbi1 , S. Molanaei2 . 1 Pediatrics and Head of Pediatric Department – Kurdistan University of Medical Science & Health Services, 2 Kurdistan University of Medical Science, Sanandaj, Iran Introduction: Kawasaki disease (KD) is no. 1 acute febrile Systemic Uasculitis that involves children under 5 years. Etioloyy is unknown. There is no Labaratory test to diaynosis Kawasaki diseuse, so that, diagnosis is clinical. The most serious complications are Cardiovascular. Coronary artery aneurysms occur in 25% of patients. Intravenous Immunoglobulin (IVIG) within 10 days of onset can prevent coronary artery involvement. Methods: In this study, medical records of 20 patient with kawasaki disease admitted to Besat hospital from 1980 to 1984 were analysed. Results: Age range was 18 months to 10 years. Mean age was 56.4 months. Male to female ratio was 3 to 2. This disease was seen in summer more then other seasons. 70% of patients met diagnostic criteria for KD but 30% had atypical presentation. Fever was seen in 100%, mocusal changes in 80%, bilateral conjunctivitis in 75%, skin rashs in 75%, cervical lymphadenopathy in 60% of all patients. Echocardiography was done in 14 cases. No aneurysm was reported, but a case had mild mitral regurgitation. 15 patients (75%) were treated with IVIG and Aspirin, 3 patients (15%) received Aspirin only, 2 patients (10%) received no treatment. There was no mortality. Conclusion: This study showed that Kawasaki disease is not uncommon in Kurdistan province. Because there is no laboratory test to distinguish the disease, diagnosis is based on clinical findings, so that, attention to clinical manifestations and early diagnosis in acute phase of the disease can prevent the coronary artery aneurysms that are the most common cause of mortality.
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(CVP) <40%. The CVP of 26 patients between post-setting and presetting were 22.24±4.21VS 74.12±11.35 (P < 0.01). With RAP on, cumulative atrial pacing (CAP) of 9 pts (9/26; 34.62%) is less than 40% while the number were 7 pts (7/26; 26.92%) with RAP off. The CAP of 26 patients between post-setting and pre-setting were 41.81±8.04 VS 57.19±9.82 (P > 0.05). Conclusion: The function of refined ventricular pacing (RVP) can reduce unnecessary right ventricular apical pacing and improve clinical outcomes. P051 Impact of Pharmacist Intervention on Glycemic Control and Cardiovascular Risks Management in Hypertensive Type 2 Diabetic Patients in Primary Care Settings V.W.Y. Lee, K.K.Y. Chu, S.S.K. Lam, W.Y.S. Leung. School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
P050 Refined Ventricular Pace Ameliorates Unnecessary Right Ventricular Apical Pacing in Patients with Bradyarrhythmia
Objective: To develop a model of pharmacist clinic for hypertensive type 2 diabetic patients in primary care settings and to evaluate the impact on glycemic control and cardiovascular risk. Methods: It was a prospective randomized controlled trial. Patients were randomized to the pharmacist group (PG) received individualized patient education, review of drug regimen and the evaluation of drug compliance. Primary endpoint was the change in hemoglobin A1c (HbA1c ). Secondary outcome measures included the change in the 10-year cardiac risk scores, systolic and diastolic blood pressure (BP), random blood glucose, lipid panels, and patients’ HbA1c and BP treatment goal attainment rates. Results: 109 patients completed the study. Patients in PG (n = 54) had a significant reduction in HbA1c compared with those in the control group (CG) (n = 55) (PG: −1.0±1.8% vs CG: −0.2±0.9%, p < 0.05). Patients in PG showed a greater decrease in coronary heart disease (CHD) (PG: −4.16±10.65% vs CG: −1.18±6.78%, p = 0.13) and fatal CHD risk scores (PG: −3.46±9.72% vs CG: −0.94±5.98%, p = 0.14) than the control. No reductions were noted in CVA (PG: 0.50±1.82 vs CG: 0.77±2.41, p = 0.33) and fatal CVA risk scores (PG: 0.16±0.51 vs CG: 0.07±0.84, p = 0.54) in both groups. Conclusion: Structured pharmaceutical care in hypertensive type 2 diabetic patients improved glycemic control in the primary care settings. The benefit in cardiac risks management needed to be further investigated.
C.Y. Lin, L. Liu, D.L. Chen, H.W. Fei, Y.H. Liang, S.L. Chen. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medicine Science, Guangzhou, China
P052 Reconstruction and Visualization of Left Ventricular Torsion using a Prolate Spheroidal B-solid Model
Objective: To investigate the clinical effect of refined atrial pacing (RAP) and refined ventricular pacing (RVP) function by the Vitatron T Series dual-chamber pacemaker on reducing right ventricular apical pacing. Methods: The study included 30 consecutive patients with sick sinus syndrome or non-three degree atrioventricular block admitted for pacemaker implantation in GuangDong Provincial Cardiovascular Institute. 11 patients were implanted T60 pacemaker and 19 pts were planted T70 pacemaker. Atrial and ventricular leads were routinely paced in the right atrial auricle and right ventricular apex respectively. After 1 month of implantation, The RAP and RVP function will be turned on during 2 months’ follow-up. AV Delay Extension was set to 120 ms, Atrial hysterisis was set to 100 ms. Mode switch was set to automatic (Auto), Max PAV Delay was set to 220 ms. 2 months later, Atrial and ventricular pacing percentage were measured and compared between pre-setting and post-setting. Results: 4 of these patients were excluded from the study because of pacing dependency (3 pts) and lost to follow-up (unknown, 1 pts). When RVP was turned on, there were 21 pts (21/26; 80.77%) with cumulative ventricular pacing (CVP) <40%; While RVP was set off, only 4 pts (4/26; 15.38%) were cumulative ventricular pacing
H.S. Wu1 , L.S. Wang1 , J. Qin1 , T.T. Wong1 , P.A. Heng1 , C.M. Yu2 . Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China; 2 Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China 1
Objective: This study aims at developing a novel method for highaccuracy 3D reconstruction and visualization of left ventricular (LV) torsion using a prolate spheroidal B-solid model, which is essential in examining myocardial dysfunction, such as diastolic heart failure and situs inversus totalis (SIT). Methods: Tagged MRI of a patient with diastolic heart failure and one healthy volunteer were performed on a Siemens Sonata 1.5T MRI Scanner using a breath-hold spatial modulation of magnetization (SPAMM). From the end-diastole, we tracked the tags using an optimized Harmonic Phase (HARP) algorithm. Then, we built a 3D prolate spheroidal B-solid model to describe the typical LV shape. During the beating cycle, the LV torsion was reconstructed by fitting the twist motion of myocardial points to the tracked tags along the circumferential direction. Finally, the 3D LV torsion from apex region to base region was visualized in an interactive and comprehensive way.
Conclusion: This study showed that hypertension was common and an independent predictor of stroke patients in Iran. P049 Epidemiological Survey of Kawasaki Disease in Kurdish Patients in Sanandaj of Iran N. Ghotbi1 , S. Molanaei2 . 1 Pediatrics and Head of Pediatric Department – Kurdistan University of Medical Science & Health Services, 2 Kurdistan University of Medical Science, Sanandaj, Iran Introduction: Kawasaki disease (KD) is no. 1 acute febrile Systemic Uasculitis that involves children under 5 years. Etioloyy is unknown. There is no Labaratory test to diaynosis Kawasaki diseuse, so that, diagnosis is clinical. The most serious complications are Cardiovascular. Coronary artery aneurysms occur in 25% of patients. Intravenous Immunoglobulin (IVIG) within 10 days of onset can prevent coronary artery involvement. Methods: In this study, medical records of 20 patient with kawasaki disease admitted to Besat hospital from 1980 to 1984 were analysed. Results: Age range was 18 months to 10 years. Mean age was 56.4 months. Male to female ratio was 3 to 2. This disease was seen in summer more then other seasons. 70% of patients met diagnostic criteria for KD but 30% had atypical presentation. Fever was seen in 100%, mocusal changes in 80%, bilateral conjunctivitis in 75%, skin rashs in 75%, cervical lymphadenopathy in 60% of all patients. Echocardiography was done in 14 cases. No aneurysm was reported, but a case had mild mitral regurgitation. 15 patients (75%) were treated with IVIG and Aspirin, 3 patients (15%) received Aspirin only, 2 patients (10%) received no treatment. There was no mortality. Conclusion: This study showed that Kawasaki disease is not uncommon in Kurdistan province. Because there is no laboratory test to distinguish the disease, diagnosis is based on clinical findings, so that, attention to clinical manifestations and early diagnosis in acute phase of the disease can prevent the coronary artery aneurysms that are the most common cause of mortality.
S23
(CVP) <40%. The CVP of 26 patients between post-setting and presetting were 22.24±4.21VS 74.12±11.35 (P < 0.01). With RAP on, cumulative atrial pacing (CAP) of 9 pts (9/26; 34.62%) is less than 40% while the number were 7 pts (7/26; 26.92%) with RAP off. The CAP of 26 patients between post-setting and pre-setting were 41.81±8.04 VS 57.19±9.82 (P > 0.05). Conclusion: The function of refined ventricular pacing (RVP) can reduce unnecessary right ventricular apical pacing and improve clinical outcomes. P051 Impact of Pharmacist Intervention on Glycemic Control and Cardiovascular Risks Management in Hypertensive Type 2 Diabetic Patients in Primary Care Settings V.W.Y. Lee, K.K.Y. Chu, S.S.K. Lam, W.Y.S. Leung. School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
P050 Refined Ventricular Pace Ameliorates Unnecessary Right Ventricular Apical Pacing in Patients with Bradyarrhythmia
Objective: To develop a model of pharmacist clinic for hypertensive type 2 diabetic patients in primary care settings and to evaluate the impact on glycemic control and cardiovascular risk. Methods: It was a prospective randomized controlled trial. Patients were randomized to the pharmacist group (PG) received individualized patient education, review of drug regimen and the evaluation of drug compliance. Primary endpoint was the change in hemoglobin A1c (HbA1c ). Secondary outcome measures included the change in the 10-year cardiac risk scores, systolic and diastolic blood pressure (BP), random blood glucose, lipid panels, and patients’ HbA1c and BP treatment goal attainment rates. Results: 109 patients completed the study. Patients in PG (n = 54) had a significant reduction in HbA1c compared with those in the control group (CG) (n = 55) (PG: −1.0±1.8% vs CG: −0.2±0.9%, p < 0.05). Patients in PG showed a greater decrease in coronary heart disease (CHD) (PG: −4.16±10.65% vs CG: −1.18±6.78%, p = 0.13) and fatal CHD risk scores (PG: −3.46±9.72% vs CG: −0.94±5.98%, p = 0.14) than the control. No reductions were noted in CVA (PG: 0.50±1.82 vs CG: 0.77±2.41, p = 0.33) and fatal CVA risk scores (PG: 0.16±0.51 vs CG: 0.07±0.84, p = 0.54) in both groups. Conclusion: Structured pharmaceutical care in hypertensive type 2 diabetic patients improved glycemic control in the primary care settings. The benefit in cardiac risks management needed to be further investigated.
C.Y. Lin, L. Liu, D.L. Chen, H.W. Fei, Y.H. Liang, S.L. Chen. Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medicine Science, Guangzhou, China
P052 Reconstruction and Visualization of Left Ventricular Torsion using a Prolate Spheroidal B-solid Model
Objective: To investigate the clinical effect of refined atrial pacing (RAP) and refined ventricular pacing (RVP) function by the Vitatron T Series dual-chamber pacemaker on reducing right ventricular apical pacing. Methods: The study included 30 consecutive patients with sick sinus syndrome or non-three degree atrioventricular block admitted for pacemaker implantation in GuangDong Provincial Cardiovascular Institute. 11 patients were implanted T60 pacemaker and 19 pts were planted T70 pacemaker. Atrial and ventricular leads were routinely paced in the right atrial auricle and right ventricular apex respectively. After 1 month of implantation, The RAP and RVP function will be turned on during 2 months’ follow-up. AV Delay Extension was set to 120 ms, Atrial hysterisis was set to 100 ms. Mode switch was set to automatic (Auto), Max PAV Delay was set to 220 ms. 2 months later, Atrial and ventricular pacing percentage were measured and compared between pre-setting and post-setting. Results: 4 of these patients were excluded from the study because of pacing dependency (3 pts) and lost to follow-up (unknown, 1 pts). When RVP was turned on, there were 21 pts (21/26; 80.77%) with cumulative ventricular pacing (CVP) <40%; While RVP was set off, only 4 pts (4/26; 15.38%) were cumulative ventricular pacing
H.S. Wu1 , L.S. Wang1 , J. Qin1 , T.T. Wong1 , P.A. Heng1 , C.M. Yu2 . Department of Computer Science and Engineering, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China; 2 Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China 1
Objective: This study aims at developing a novel method for highaccuracy 3D reconstruction and visualization of left ventricular (LV) torsion using a prolate spheroidal B-solid model, which is essential in examining myocardial dysfunction, such as diastolic heart failure and situs inversus totalis (SIT). Methods: Tagged MRI of a patient with diastolic heart failure and one healthy volunteer were performed on a Siemens Sonata 1.5T MRI Scanner using a breath-hold spatial modulation of magnetization (SPAMM). From the end-diastole, we tracked the tags using an optimized Harmonic Phase (HARP) algorithm. Then, we built a 3D prolate spheroidal B-solid model to describe the typical LV shape. During the beating cycle, the LV torsion was reconstructed by fitting the twist motion of myocardial points to the tracked tags along the circumferential direction. Finally, the 3D LV torsion from apex region to base region was visualized in an interactive and comprehensive way.