P080 Telangiectases: New treatment modalities

S172

Posters - Dermatological

Case Report: A girl, 6 years old, with a port-wine stain covering most of the right half of her face. She was treated with dye laser for the fourth time in general anesthesia administered by mask using sevoflurane and 100% oxygen. N20z was used only in the initial phase of the anesthesia. The intraocular pressure was measured before the laser treatment. The port-wine stain was treated with dye laser, 6.5 J/cm2, starting on the forehead. The second laser pulse close to the upper part of the eyebrown induced a blaze and the eyebrown was in a moment destroyed by the fire. The mask fitted well to the face and there was no obvious leakage. Comment: Up till now we have used the same technique in over 300 operations in children for port-wine stain, most of them in the face. Hair is frequently singed but has never ignited. Even if very rare, however, the case presented points at the potential hazard of the dye laser when operated in the face of a patient receiving inhalation anesthesia.

I PO79

Tattoos: Sala-microdermabrasion radiobistuty

Claudio Comacchi, Tore110 Lotti ’ . Department Dermatology, Dermatology,

University University

with of

of Florence; ‘Department of Siena, Italy

of

Various methods are used for tattoo removal, but all leave at least some scar marks (1). In addition to the various treatments available (excision, salabrasion, dermabrasion, lasers, cryosurgery, electrofulguration, grafting and tissue expansion) we have evaluated the efficacy of sala-microdermabrasion with radiobistury (AM 308 N - E.P.E.M., Florence, Italy). We treated five patients with tattoos - operating in the super pulsed mode, without local anaesthetic, gently brushing with the electrode on the macules. As the tattoos become prominent, a sodium chloride precipitate in saturated solution is applied using a cotton swab. The site is washed with saline solution after l-2 hours. A dry black escar forms after some days and falls off in 4-5 weeks. Good aesthetic results were obtained without any further complications. Our limited data suggest that sala-microdermabrasion may represent the treatment of choice for tattoo removal. Reference [l] Bose SK, Ortonne JP. Pigmentation: dyschromia. In: Baraa R and Maibach HI eds. Cosmetic Dermatology. London, Martin Dunitz, 1994,277-298,

Telangiectases: New treatment modalities I PO80 C. Comacchi, T. Lotti ’ Department of Dermatology, University University

of Florence; ‘Department of Siena, Italy

of Dermatology,

Telangiectases are permanently dilated capillaries and venules in the papillary and subpapillary dermis. This condition frequently occurs on the face or legs, and can be divided into primary and secondary types. Secondary telangiectases can be caused by exogenous influences (chronic exposure to sun, long-term local treatment with corticosteroids) or as a result of skin diseases (scleroderma, crest syndrome, lupus erythematosus, etc) (1). Protection against ultraviolet light and extreme

Surgery/Dermatopathology

temperatures may be important for telangiectases of the face, while directional doppler ultrasound is of great help in the evaluation of telangiectases of the legs (1). Treatment modalities of telangiectases include programmed diathermocoagulation, laser beam treatment, sclerotherapy, cryotherapy, crenotherapy, topical treatment, and camouflage make-up (1). We evaluated the efficacy of programmed diathermocoagulation (AM 308 N - E.P.E.M., Florence, Italy) and sclerotberapy (30.5 G needle, 0.5% polidocanol) in the treatment of 14 patients with telangiectases on the face and legs. The new diathermy technique permits operation in pulsed or super pulsed mode, without local anaesthetic, while sclerotherapy with 0.5% polidocanol reduces the possibility of complications, such as brown staining, venular thrombosis, skin necrosis. Good aesthetic results are usually obtained without any complications. Our data suggest that programmed diathermocoagulation may represent the treatment of choice for small and medium-sized telangiectases on the face or legs. Sclerotherapy is instead, in our opinion, the basic treatment for larger telangiectases. Reference

[l] Ramelet AA. Telangiectases. In: Baran R and Maibach HI eds. Cosmetic Dermatology. London, Martin Dunitz, 1994.259-265, I PO81

Application of Lamisil in the treatment of trychophytosis

M.R. Tsoy. Research Venereology,

Tashkent,

Institute of Dermatology Uzbekistan

and

The work was aimed at study of Lamisil effect on trychophytia course induced by zoophilic fungi. 45 children with trychophytia aged from 3 to 12 were observed. Lanisil was administered according to body mass. Under 20 kg-62.5 mg, from 20 to 40 kg-125 mg once a day during 14 days, in some cases - 2 1. External treatment was performed just in infiltrative-suppurative trychophytia by dressings with 10% ichthyol liniment. Results showed clinical and micologic recovery in ringworm of the body in average 14.2 days, in infiltrative - 20.5, infiltrative purulent - 29.3. Investigation of biochemical blood in dices and hepatic MOS showed that lamisil did not effect detoxication function and hepatic enzymes activity. Preparation is well tolerated. Side effects were noted in 2 children as small popular eruptions in separate body areas that regressed if discontinued. Studies performed proved high sensibility of lamisil as regard dermatophytes. Shortening of treatment allows to recommend it as principal remedy. I PO82 UV-irradiated human skin exhibits altered

expression of p53-regulated proteins

A. O’Grady ’ , E.W. Kay ’ , D.B. McKenna *, M.A. Bennett ’ , M.B. Leader’, G.M. Murphy*. ‘Departments of Histopathology; Ireland

*Dermatology

Beaumont

Hospital,

Dublin,

The distribution of p2 1Wafl’Cirl , MDM2 and Bax/Bcl-2 proteins in UV-irradiated and unirradiated human skin were examined immunohistochemically and compared with p53 protein levels. Sun-protected buttock skin from three volunteers was exposed