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P11.07 Intravascular Catheter Related Infections in Neonatal Care Unit at Mansoura University Children's Hospital
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Abstracts, 6th Int. Conf. of the Hospital Infection Society, 15–18 October 2006, Amsterdam, The Netherlands
unprotective levels of antibodies. Among them 92.05% were females and 7.75% males. The 605 of unprotectivc health care workers had received the ful1 vaccination scheme. Only 20% did not receive any vaccination and another 20% were partially vaccinated. 60% of the health care workers at UGH have protective antibodies against HBV while 38% have susceptibility to get infection with HBV receive any. Different behavior among the Departments at UGH was observed as well as the difference in protection levels associated to the age and sex. P11.05 Reporting Rate of Occupational Injuries and Exposure to Blood Borne Infections among Jordanian Healthcare Workers: a Descriptive Study Z. Hassan *. Hashemite University, Jordan Background: National data are not available on the annual number of needle stick and other injuries among Jordanian healthcare workers. Aims: Examine the predictors related to reporting rate of occupational exposure to blood or body fluids among Jordanian healthcare workers. Methods: A correlational descriptive design will be utilized in this study. The target population will consist of Jordanian healthcare workers. The sample size will be 2000 participants. Data will be collected using “Survey of Healthcare Personnel on Occupational Exposure to Blood and Body Fluids” which was developed by CDC. Linear regression analysis, will be utilized to examine the relationships between the independent variables i.e. (age, gender, position title, type of unit, day or night shift, years of experience, level of education, type of agency, and timing of occurrence of injuries) and the dependant variable i.e. (reporting occupational rate of occupational exposure to blood-borne viruses). P11.06 Impact of Infection Control Program on the Prevalence of Nosocomially Urinary Tract Infection in an Egyptian University Affiliated Hospital N. Omar1 *, M. Ali2 , Specialized Medical Hospital I.C. Team1 . 1 Faculty of Medicine, Mansoura University, Egypt, 2 Faculty of Medicine, Egypt Background & Objectives: Area-specific monitoring studies aimed to gain knowledge about the type of pathogens responsible for nosocomial urinary tract infections (NUTIs) and their resistance patterns, and also to evaluate the impact of infection control program. The aim of the present study was to estimate the incidence of NUTIs in two studied periods and to evaluate the effectiveness of the infection control measures adopted against NUTIs in a tertiary care hospital at Mansoura, Egypt. Methods: Cases with UTI were retrospectively analyzed in two 6-month study periods. We compared between the two study periods as regard the following: prevalence of catheterassociated urinary tract infection, and between the causative urinary pathogens, and their antibiotic susceptibility in the 2 study periods. Result: Data on 2537, 2189 inpatients with 21% and 22.9% nosocomial infection prevalence were analyzed in the two studied periods. Patients in periods 1 and 2 were similar with regard to sex, age, and underlying disease. The NUTI prevalence was significant increased from period 2 than period 1( 34.9% vs 22.9% [P = 0.001]. Catheter-associated urinary tract infection (CAUTI) prevalence was not statistically significant increased from 16% to 24%, [P = 0.013]. The duration of urinary catheterization was statistically significantly increased during the second period [P = 0.001]. No statistically-significant changes in the distribution of pathogens over the two studied periods as E. coli was the most common pathogens in both
periods (55.4%vs 45%, [P = 0.111]). The mean susceptibility for the commonest UTI pathogens (E. coli& K. pneumoniae) was high for both of Amikin and imipenem in both studied periods. Conclusions: The results indicate an increase in the prevalence CAUTI. The increasing coincides with improper preventive programm focused on catheter policy and UTI and defects in collaboration among different parts of a health care organization. P11.07 Intravascular Catheter Related Infections in Neonatal Care Unit at Mansoura University Children’s Hospital N. Omar1 *, S. El Sallab2 , T. El Shahat2 , M. Shokeir2 . 1 Faculty of Medicine, Mansoura University, Egypt, 2 Pediatrics Depts, Faculty of Medicine, Mansoura University, Egypt Background and Objective: Catheter-related infections (CRIs) is commonly encountered in the neonatal intensive care unit (NICU). The aim of the present work is to determine the incidence of bacterial infection in catheter related blood stream infections (CRBSIs) among neonates with intravascular catheters and to determine the relation between infection and the type of catheter used. Methodology: A prospective study was carried out at the NICU of a tertiary care hospital at Mansoura, Egypt. A total of 110 of selected neonates with vascular catheters: 52 with peripheral intravenous canulae (PIV); 19 with central venous catheter (CVC); 19 with umbilical venous catheter (UVC) and 6 with peripheral long lines. Catheter tip were cultured on removal and blood culture was done to cases with signs of infections either local-catheter–related infection (L-CRIs) or CRBSIs. Systematic bacteriological identification were done for each significant isolate. Result: 84 out of 110 neonates (76.3%) were nosocomially infected, 53 of them (63.1%) had CRIs. Among those neonates with CRIs, 29 neonates (54.7%) had CRBSIs, 18 (34%) developed L-CRIs, and 6 (11.3%) developed phelebitis. L-CRIs associated with CRBSIs were observed only in 10 neonates (9.1%). Twenty nine neonates developed CRBSIs, 9 of them (31.0%) with PIV cannulae, 7 (24.1%) with more than one type of CVCs, 5 (17.2%) with UVCs and 2 (6.9%) neonates with midline catheter. CoNS were found to be the commonest pathogens that caused CRBSIs in the studies neonates (31%), followed by both group D Strep. and K. pneumoniae each of them account for 17.2%, S. aureus was found to cause colonization of catheters in 22.2%, followed by both CoNS and E. coli in 16.7%. Conclusion: Catheter colonization rates in this population were high. Well–organized programs of infection control that enable health-care providers to monitor and evaluate care is critical for the success of efforts to prevent CRIs is required. P11.08 Etiology, Resistance and Risk Factors Associated with Outcome Among 1,121 Bloodstream Infection in Intensive Care Units E. Gir˜ ao, A. Levin, M. Basso, S. Gobara, L. Brasileiro, M. Ayara, E. Medeiros, A. Barone, S. Costa *. Hospital das Cl´ ınicas, Brazil Objective: to characterize the incidence and antimicrobial resistance trends of the main agents causing bloodstream infections (BSI) in the ICUs and the risk factors associated with death in a large university-affiliated hospital. Design: All cases of nosocomial BSI in the university-affiliated hospital with twelve ICUs were identified by surveillance, using Centers for Diseases Control and Prevention criteria over a 5-year period. The following variables were evaluated: age, sex, length of stay, underlying diseases, central venous catheter, and outcome. Data were analyzed using EpiInfo 6.04 software. The c2 test for linear trend was used to evaluate the distribution of the most common agents and the proportion of resistance during
Abstracts, 6th Int. Conf. of the Hospital Infection Society, 15–18 October 2006, Amsterdam, The Netherlands
unprotective levels of antibodies. Among them 92.05% were females and 7.75% males. The 605 of unprotectivc health care workers had received the ful1 vaccination scheme. Only 20% did not receive any vaccination and another 20% were partially vaccinated. 60% of the health care workers at UGH have protective antibodies against HBV while 38% have susceptibility to get infection with HBV receive any. Different behavior among the Departments at UGH was observed as well as the difference in protection levels associated to the age and sex. P11.05 Reporting Rate of Occupational Injuries and Exposure to Blood Borne Infections among Jordanian Healthcare Workers: a Descriptive Study Z. Hassan *. Hashemite University, Jordan Background: National data are not available on the annual number of needle stick and other injuries among Jordanian healthcare workers. Aims: Examine the predictors related to reporting rate of occupational exposure to blood or body fluids among Jordanian healthcare workers. Methods: A correlational descriptive design will be utilized in this study. The target population will consist of Jordanian healthcare workers. The sample size will be 2000 participants. Data will be collected using “Survey of Healthcare Personnel on Occupational Exposure to Blood and Body Fluids” which was developed by CDC. Linear regression analysis, will be utilized to examine the relationships between the independent variables i.e. (age, gender, position title, type of unit, day or night shift, years of experience, level of education, type of agency, and timing of occurrence of injuries) and the dependant variable i.e. (reporting occupational rate of occupational exposure to blood-borne viruses). P11.06 Impact of Infection Control Program on the Prevalence of Nosocomially Urinary Tract Infection in an Egyptian University Affiliated Hospital N. Omar1 *, M. Ali2 , Specialized Medical Hospital I.C. Team1 . 1 Faculty of Medicine, Mansoura University, Egypt, 2 Faculty of Medicine, Egypt Background & Objectives: Area-specific monitoring studies aimed to gain knowledge about the type of pathogens responsible for nosocomial urinary tract infections (NUTIs) and their resistance patterns, and also to evaluate the impact of infection control program. The aim of the present study was to estimate the incidence of NUTIs in two studied periods and to evaluate the effectiveness of the infection control measures adopted against NUTIs in a tertiary care hospital at Mansoura, Egypt. Methods: Cases with UTI were retrospectively analyzed in two 6-month study periods. We compared between the two study periods as regard the following: prevalence of catheterassociated urinary tract infection, and between the causative urinary pathogens, and their antibiotic susceptibility in the 2 study periods. Result: Data on 2537, 2189 inpatients with 21% and 22.9% nosocomial infection prevalence were analyzed in the two studied periods. Patients in periods 1 and 2 were similar with regard to sex, age, and underlying disease. The NUTI prevalence was significant increased from period 2 than period 1( 34.9% vs 22.9% [P = 0.001]. Catheter-associated urinary tract infection (CAUTI) prevalence was not statistically significant increased from 16% to 24%, [P = 0.013]. The duration of urinary catheterization was statistically significantly increased during the second period [P = 0.001]. No statistically-significant changes in the distribution of pathogens over the two studied periods as E. coli was the most common pathogens in both
periods (55.4%vs 45%, [P = 0.111]). The mean susceptibility for the commonest UTI pathogens (E. coli& K. pneumoniae) was high for both of Amikin and imipenem in both studied periods. Conclusions: The results indicate an increase in the prevalence CAUTI. The increasing coincides with improper preventive programm focused on catheter policy and UTI and defects in collaboration among different parts of a health care organization. P11.07 Intravascular Catheter Related Infections in Neonatal Care Unit at Mansoura University Children’s Hospital N. Omar1 *, S. El Sallab2 , T. El Shahat2 , M. Shokeir2 . 1 Faculty of Medicine, Mansoura University, Egypt, 2 Pediatrics Depts, Faculty of Medicine, Mansoura University, Egypt Background and Objective: Catheter-related infections (CRIs) is commonly encountered in the neonatal intensive care unit (NICU). The aim of the present work is to determine the incidence of bacterial infection in catheter related blood stream infections (CRBSIs) among neonates with intravascular catheters and to determine the relation between infection and the type of catheter used. Methodology: A prospective study was carried out at the NICU of a tertiary care hospital at Mansoura, Egypt. A total of 110 of selected neonates with vascular catheters: 52 with peripheral intravenous canulae (PIV); 19 with central venous catheter (CVC); 19 with umbilical venous catheter (UVC) and 6 with peripheral long lines. Catheter tip were cultured on removal and blood culture was done to cases with signs of infections either local-catheter–related infection (L-CRIs) or CRBSIs. Systematic bacteriological identification were done for each significant isolate. Result: 84 out of 110 neonates (76.3%) were nosocomially infected, 53 of them (63.1%) had CRIs. Among those neonates with CRIs, 29 neonates (54.7%) had CRBSIs, 18 (34%) developed L-CRIs, and 6 (11.3%) developed phelebitis. L-CRIs associated with CRBSIs were observed only in 10 neonates (9.1%). Twenty nine neonates developed CRBSIs, 9 of them (31.0%) with PIV cannulae, 7 (24.1%) with more than one type of CVCs, 5 (17.2%) with UVCs and 2 (6.9%) neonates with midline catheter. CoNS were found to be the commonest pathogens that caused CRBSIs in the studies neonates (31%), followed by both group D Strep. and K. pneumoniae each of them account for 17.2%, S. aureus was found to cause colonization of catheters in 22.2%, followed by both CoNS and E. coli in 16.7%. Conclusion: Catheter colonization rates in this population were high. Well–organized programs of infection control that enable health-care providers to monitor and evaluate care is critical for the success of efforts to prevent CRIs is required. P11.08 Etiology, Resistance and Risk Factors Associated with Outcome Among 1,121 Bloodstream Infection in Intensive Care Units E. Gir˜ ao, A. Levin, M. Basso, S. Gobara, L. Brasileiro, M. Ayara, E. Medeiros, A. Barone, S. Costa *. Hospital das Cl´ ınicas, Brazil Objective: to characterize the incidence and antimicrobial resistance trends of the main agents causing bloodstream infections (BSI) in the ICUs and the risk factors associated with death in a large university-affiliated hospital. Design: All cases of nosocomial BSI in the university-affiliated hospital with twelve ICUs were identified by surveillance, using Centers for Diseases Control and Prevention criteria over a 5-year period. The following variables were evaluated: age, sex, length of stay, underlying diseases, central venous catheter, and outcome. Data were analyzed using EpiInfo 6.04 software. The c2 test for linear trend was used to evaluate the distribution of the most common agents and the proportion of resistance during