- Email: [email protected]
P192 An eighth week pulmonary rehabilitation in patients with non-cystic fibrosis bronchiectasis - observational study
Poster Walks Poster Walk 5: Epidemiology/Rehabilitation
P192 An eighth week pulmonary rehabilitation in patients with non-cystic fibrosis bronchiectasis observational study M. Balteanu1,2, R. Traistaru3, N. Cioran1,4, M. Tanasescu1, P. Postolache5 1 Institute of Pneumology Marius Nasta, 2University Titu Maiorescu, Bucharest, 3University of Medicine and Pharmacy, Craiova, 4University of Medicine and Pharmacy Carol Davila, Bucharest, 5University of Medicine and Pharmacy Iasi, Iasi, Romania Bronchiectasis is a suppurative lung disease characterized by wide and distorted bronchi, with daily cough and sputum production and infectious exacerbations. Etiologies and treatments are diverse from lung hygiene with mucolytic agents and physiotherapy, anti-inflammatory agents and antimicrobial agents. International guidelines recommend the inclusion of patients with bronchiectasis in pulmonary rehabilitation (PR) to improve exercise capacity and health-related quality of life (HRQoL). Purpose: The aim of our study was to analyze the effects of rehabilitation program on quality of life and physical performance (express through 6MWD value - distance walking in 6 minutes) and pulmonary function in patients with bronchiesctasis. Methods: 33 subjects with bronchctasis and bronchial obstruction with mean FEV1 50% were assigned to a clinic treatment group (n¼17; 13 males, 4 females; mean age [SD] ¼ 638years) or an clinical and exercise group (n¼14, 10 males, 4 females; mean age [SD]¼ 657 years). Subjects in the clinic treatment group received only pharmacological treatment, subjects in the exercise group received an rehabilitation program over an 8-week period (monitoring pharmacotherapy, education, exercise and respiratory muscle training). Measured outcomes were the distance walked in 6 minutes (6MWD), FEV1, FVC, the generic QoL scale St. George’s Respiratory Questionnaire (SGRQ). Differences parameter values between groups were tested by ANOVA test.
Conclusions: Although both groups improved by 8 weeks, subjects in the exercise group achieved larger improvements in 6MWD values and SGRQ scores. Compared with MID values for 6MWD in COPD founded in literature, our values of 6MWD changes are lower. DOI:
http://dx.doi.org/10.1016/j.chest.2017.04.096
Copyright ª 2017 American College of Chest Physicians and Swiss Respiratory Society SGP. Published by Elsevier Inc and Karger. All rights reserved.
journal.publications.chestnet.org
91A
POSTER WALKS
Results: Both groups showed clinically and statistically significant improvements in 6-minute walk distances and SGRQ scores at 8 weeks; improvements were still evident in both groups at 3 month. By 2 weeks, SGRQ scores had improved by 4 units in the clinic treatment group and by 6 units in the exercise group. 6 MWD had improved in both groups, with 2743m in exercise group and 2023m in clinical group. Important differences were observed in the mean changes of 6MWD at 8 weeks. At 3 months, both groups were substantially and about equally improved over baseline measurements. Subjects in the exercise treatment group were more satisfied with the overall outcome of their rehabilitative treatment compared with subjects in the clinical group.
P192 An eighth week pulmonary rehabilitation in patients with non-cystic fibrosis bronchiectasis observational study M. Balteanu1,2, R. Traistaru3, N. Cioran1,4, M. Tanasescu1, P. Postolache5 1 Institute of Pneumology Marius Nasta, 2University Titu Maiorescu, Bucharest, 3University of Medicine and Pharmacy, Craiova, 4University of Medicine and Pharmacy Carol Davila, Bucharest, 5University of Medicine and Pharmacy Iasi, Iasi, Romania Bronchiectasis is a suppurative lung disease characterized by wide and distorted bronchi, with daily cough and sputum production and infectious exacerbations. Etiologies and treatments are diverse from lung hygiene with mucolytic agents and physiotherapy, anti-inflammatory agents and antimicrobial agents. International guidelines recommend the inclusion of patients with bronchiectasis in pulmonary rehabilitation (PR) to improve exercise capacity and health-related quality of life (HRQoL). Purpose: The aim of our study was to analyze the effects of rehabilitation program on quality of life and physical performance (express through 6MWD value - distance walking in 6 minutes) and pulmonary function in patients with bronchiesctasis. Methods: 33 subjects with bronchctasis and bronchial obstruction with mean FEV1 50% were assigned to a clinic treatment group (n¼17; 13 males, 4 females; mean age [SD] ¼ 638years) or an clinical and exercise group (n¼14, 10 males, 4 females; mean age [SD]¼ 657 years). Subjects in the clinic treatment group received only pharmacological treatment, subjects in the exercise group received an rehabilitation program over an 8-week period (monitoring pharmacotherapy, education, exercise and respiratory muscle training). Measured outcomes were the distance walked in 6 minutes (6MWD), FEV1, FVC, the generic QoL scale St. George’s Respiratory Questionnaire (SGRQ). Differences parameter values between groups were tested by ANOVA test.
Conclusions: Although both groups improved by 8 weeks, subjects in the exercise group achieved larger improvements in 6MWD values and SGRQ scores. Compared with MID values for 6MWD in COPD founded in literature, our values of 6MWD changes are lower. DOI:
http://dx.doi.org/10.1016/j.chest.2017.04.096
Copyright ª 2017 American College of Chest Physicians and Swiss Respiratory Society SGP. Published by Elsevier Inc and Karger. All rights reserved.
journal.publications.chestnet.org
91A
POSTER WALKS
Results: Both groups showed clinically and statistically significant improvements in 6-minute walk distances and SGRQ scores at 8 weeks; improvements were still evident in both groups at 3 month. By 2 weeks, SGRQ scores had improved by 4 units in the clinic treatment group and by 6 units in the exercise group. 6 MWD had improved in both groups, with 2743m in exercise group and 2023m in clinical group. Important differences were observed in the mean changes of 6MWD at 8 weeks. At 3 months, both groups were substantially and about equally improved over baseline measurements. Subjects in the exercise treatment group were more satisfied with the overall outcome of their rehabilitative treatment compared with subjects in the clinical group.