S198
Posters
- Miscellaneous
Igs or C3) at the dermoepidermal junction located both in the roof and bottom of a blister provoked on perilesional skin by a solution of 1 M nace. The lesions of the skin responded to oral treatment with dapsone, but mucosal involvement required immunosupression with azathioprine. The clinical manifestations of this patient are indistinguishable from those of cicatricial pemphigoid. Only the immunofluorescence findings made possible the diagnosis of adult linear IgA disease. I P196 The acute effect of smoking on cutaneous
microcirculation blood flow in habitual smokers and non smokers
Cl. Monfrecola, G. Riccio, C. Savarese, G. Posteraro, E.M. Procaccini. Dept. of Dermatology, University “Federico II”,
Naples,
I PI 98 Subcutaneous
manifestation of metastatic thyroid carcinoma
Italy
Smoking is known to be a primary cause of chronic harmful effects on vascular system. It also induces some acute effects on the coronary circulation and on the ophthalmic artery. Our purpose was to assess the effect of a single cigarette smoking on cutaneous blood flow in habitual smoker as well as in non smoker subjects. A Laser Doppler flowmeter has been used to perform measurements of cutaneous microcirculation. Flowmetric data have been recorded (i) before smoking, (ii) inhaling an unlighted cigarette, (iii) during a cigarette smoking, (iiii) 2 and (iiiii) 5 minutes after smoking. Results show that the smoke of a single cigarette acts on cutaneous microcirculation reducing blood flow in both groups of patients (38.1% reduction in smoker subjects and 28.1% reduction in non smoker ones) (p < 0.01). Interestingly, the recovering phase is faster in non smoker subjects than in smoker ones; in fact, the recovering is complete 2 minutes and 5 minutes after a cigarette smoking in non smoker and in smoker subjects respectively. In conclusion the smoke of a single cigarette decreases the cutaneous blood flow in habitual smoker as well as in non smoker subjects. Moreover the slower recovering phase of smoker subjects suggest that their microcircle is become inured to smoke. 0PI 97 The prevalence of occupational dermatoses in the Cukurova region M.A. Acar, M. Karakag, V.L. Aksungur, Y.G. Denli, M. Baba, H. Kavukcu, H.R. Memigoglu. Cukurova University, Faculty of Medicine,
contact dermatitis 32 (5.94%), tinea infection 117 (21.74%) acne 82 (15.24%), pruritus 56 (10.40%), urticaria 28 (5.20%) pyodermia 20 (3.71%) psoriasis 21 (3.90%), scabies 28 (5.20), lichen planus 27 (5.01), keratoderma 13 (2.41%) and others 54 (10.03%). Skin tests have been planned for application to patients with allergic contact dermatitis, irritant contact dermatitis and urticaria since these may be associated with their occupation. It was observed that contact dermatitis occurred frequently in susceptible persons when protective gloves were not used. Tinea infections were the most common dermatological disease which are associated with the climate of the region rather than with their occupation. This study has been supported by the project No: TF.94.34 of Cukurova University Research Fond.
Department
of Dermatology,
Adana,
Turkey
The aim of this study was to determine the rate of occupational dermatoses in factories in the Cukurova region. After meeting with the managers of the industrial establishments in question, a dermatological examination was made of the workers. For 6 months, a dermatological examination was made of 2960 men and 1040 women (totaling 4000) in various branches of industry especially in the following 12 fields: Plastic, weaving, dye, thread, margarine, tobacco and textile dyeing: Skin diseases were found in 617 people (332 men and 285 women whose ages ranged between 18-54). Dermatological disease was observed as follows: Allergic contact dermatitis 81 (15.05%), irritant
L. Fabricio ‘3’ , M. D’Incan’, P. Souteyrand 2. ‘Department Curitiba, Brazil, 2Department Hotel-Dieu, Clermont-Ferrand,
H. Roger 2, S. Mansard2, of Dermatology, of Dermatology, France
FEMPAR, CRHU
An 89-year-old woman had a 4 month history of a progressively enlarging subcutaneous mass on the head. Examination revealed a firm, non-throbbing, subcutaneous mass 4 cm in diameter, localized in the right temporal region, with normal covering skin. A goitre and a homolateral exophtalmos were noted. She complained of intermittent headache. A computed tomographic scan of the head was performed before routine biopsy, fortunately, as it showed a large right temporal mass with osteolytic and cerebral invasion features. Metastatic thyroid carcinoma was diagnosed on the basis of histological specimens. During biopsy, performed by a neurosurgeon, the patient had a haemorrhage. She refused surgical treatment and thus radiation therapy was recommended. This report shows that care should be taken before performing biopsy in cases of subcutaneous cranial tumour to avoid potentially dangerous surgical complications. I PI 99 Systemic amyloidosis. Report of four cases: S. Cordoba, E. Vargas, J. Fraga’, E. Dauden, M. Aragties. Department Universitario
of Dermatology; de la Princesa,
‘Pathology, Hospital Madrid, Spain
Introduction: Immunoglobulin light chains related systemic amyloidoses, also called AL amyloidosis, are almost always associated with monoclonal gammopathy or myeloma. The occurrence of mucocutaneous lesions ranges from 29 to 40%. usually they become purpuric after minimal trauma, due to perivascular deposit of amyloid protein. Patients: We report four patients, two women and two men, aged ranged between 58 and 81, that assisted to our department reporting a 10 months-10 years history of white-yellowish plaques with purpuric zones. Two cases were associated with myeloma while the other two had monoclonal gammopathy. All the patients showed amyloid deposition throughout multiple organs as revealed by fine needle aspiration of subcutaneous fat and tongue, skin or bone marrow biopsies. Two cases presented diffuse plane normolipaemic xanthoma (DPNX) coexisting with amyloidosis in cutaneous lesions. One patient showed