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Abstracts, 7th International Conference of the Hospital Infection Society, 10–13 October 2010, Liverpool, UK / Journal of Hospital Infection 76S1 (2010) S1–S90
Conclusion: In our setting, exposure to pathogen appears to be continual. Adherence to hand washing, good general hygiene and scrupulous attention to preparing nasogastric milk feeds and proper antibiotic usage is warranted to reduce burden of ND. Poster Session 31 – Tuberculosis P31.01 Evaluation of tuberculosis case contacts study program P. Garcia-Shimizu, C. Villanueva-Ruiz, M. Fuster-Perez, ´ J. Sanchez-Pay ´ a, ´ C. Escriva-Pons, J. Barrenengoa-Sanudo, ˜ A. RinconCarlavilla, A. Gonzalez-Torga. Universitary General Hospital of Alicante, Spain Background: One of the basic strategies of control of the Tuberculosis is the accomplishment of the studies of contact of the cases. Objective: Evaluate the degree of accomplishment with the recommendations and its decisive factors in a tuberculosis case contacts study. Methods: Observational, retrospective cohort study of tuberculosis case contacts. We included 1059 contacts corresponding to the tuberculosis cases diagnosed during the period 2000–2005. The outcome variable has 2 categories (end of the study or retirement). There are two types of independent variables: related to the case (age, sex, home country, baciloscopy, risk factors) and related to the contact (age, sex, home country, previous family exposure, previous workplace exposure, comorbidity, kind of contacts, tuberculosis infection, advice). The analysis unit was the contact and variables of the index case were applied to all of them. The Chi-square test was used to study the association of the variables, relative risk with confidence interval respectively were calculated to asses its dimension, for the significantly statistic variables logistic regression method was used. Results: The global compliance with the recommendations was 67.8%, the compliance with the recommendations was 72% and 53% when the recommendation was primary chemoprophylaxis and secondary chemoprophylaxis respectively. Variables significantly associated with retirement in multivariate analysis were: index case age under 35, RR = 2.1 (1.4–3.0); positive baciloscopy, RR = 1.8 (1.2–2.7); immigrant contact, RR = 2.8 (1.4–5.7); primary chemoprophylaxis advice, RR = 0.5 (0.3–0.8). Conclusion: It is necessary to develop strategies to improve compliance with the recommendations of the tuberculosis case contacts directed fundamentally to tuberculosis case contacts under 35, baciloscopy positive and immigrant contact.