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P336 Hysteroscopic resection of benign intrauterine lesions in post-menopausal women
P335 ASSESSING POST MENOPAUSAL HYSTERECTOMY
P336 STATUS AFTER
MP Everett. MG Hardicre, A WM Hay, CF Westmacott, *H Towers, JO Drife, MA Smith University Department of Obstetrics & Gynaecology Leeds General Infirmary, Leeds LS2 3EX United Kingdom *Schering Healthcare
HYSTEROSCOPIC RESECTION OF BENIGN INTRAUTERINE LESIONS IN POST-MENOPAUSAL WOMEN E Grassini. M Benfatti, C Bertulessi, L Iasi, G Radici, P Capetta, Fifth Department Obstetrics and Gynecology, University of Milan, Via M. Melloni 52,20129 Milan, Italy.
197 hysterectomised women were screened between March 1994 and September 1995 for inclusion in a clinical trial to test a new oestrogen patch. The principal inclusion criteria we were required to use were: Age 40-65 years; Hysterectomy (Hx); FSH >40 IU; Oestradiol (E2) cl10 pmol/L. 57 women failed to meet the entry criteria. Some of those excluded were probably post menopausal (PM) and this raises a question about the suitability of the biochemical parameters used for the entry criteria. 7 women aged 48-65, 9-33 years post Hx, with 2520 and E2 ~150 be better criteria for PM status?
Between January 1995 and December 1995, 101 post-menopausalwomen with Abnormal Uterine Bleeding (A.U.B.) underwent an office hysteroscopy at the Vth Department of Obstetrics and Gynecology of the University of Milan. 25 patients presented a benign pathology of uterine cavity subsequently excised with hysteroscopic resection under general anesthesia. The average age was 59.84 years (range: 46-79) and no patient previously taked Hormone Replacement Therapy. The average hospital stay was 2.20 days (range: 2-3). The average hospitalization postoperative time was 1.16 days (range l-2). The hystology showed 21 endometrial polyps, 2 submucous myomas, one polyp with associated myoma and one polyp with associated simple endometrial hyperpiasia In the following two months after surgery, no patient reported recurrence of A.U.B. The complete hysteroscopic resection of the benign lesions allows us to resolve the bleeding and in the same time to support the hystology in the exclusion of any malignant changes.
P337
P338
TUBAL LIGATION AND LONG TERM HEALTH OUTCOMES: RETROSPECTIVE INFORMATION IN THE MELBOURNE WOMEN’S MIDLIFE STUDY.
COMPLIANCE TO ESTROGEN TREATMENT AFI’ER HYSTERECTOMY AND BILATERAL OOPHORECTOMY, PATIENTS LIFESTYLE AND KNOWLEDGE OF HRT EFFECl-S.
JR Taffe, E C Dud& L Dennerstein, Key Centre for Women’s Health, The University of Melbourne, Carlton, 3053, Australia.
P H&e, Gynrekologisk - Obstetrisk afd. Centralsygehuset i Naestved, 4700 Niestved, Denmark
Tubal ligation has been shown in hospital based and huge epidemiological studies to be associated with negative health outcomes in the long term. In a population based sample of 2001 Australian born women aged 45-55 years, over 40% of women interviewed had had a tubal ligation, and retrospective data on the dates of tubal ligation, hysterectomy, oophorectcmy and other health outcomes are available. Odds ratios of hysterectomy estimated from logistic regression with tubal ligation as a categorical exposure and allowing for confounders do not differ significantly from 1. Similarly there is a lack of association of tubal ligation with other serious outcomes, or with indicators of present wellbeing such as the Affectometer scale and self rated health. In interpreting these results it must be borne in mind that follow-up times are censored at ages between 45 and 55.
Eighty-two of 88 women, aged40-55, retumed a questionnaire 1-3 y atler hysterectomy and bilateral oophorectomy. Indications; bleeding disorders and/or tibroma of the uterus. At discharge f?om the hospital they receiveda prescription: 2 mg estrogen daily treatment Ninety-five% bought the estrogen withii 3 days, 97% started treatment the same day, 94% choose tablets and 99% took one tablet daily. Eighty-two% stayed on the same treatment and 99% were compliant to the treatment during the observation period. Knowledge of HRT; 99% knew that HRT existed, primary source of information (63%) is newspapers/magazines, secondary (53%) general practitioners (GP). Ninety-six% knows that HRT can treat climacteric symptoms, 90% know the effect on bone and 33% know the pos. effect on cardiovascular disease. Sixty-nine% believe that HRT is a riskfactor for developing breast cancer and 50% believes it increases body weight. Seventy-four % believes that HRT increases the quality of life. Developing climacteric symptoms 85% would contact the GP for more information and treatment, however having no symptoms 82% would not contact the GP. Lifestyle issues; 68% were non-smokers, 24% combined estrogen treatment with a natural medicine, 68% took a vitamin preparation 86% of which included calcium. Only 21 % drank more than half a liter milk daily. Seven%jogged more than 5 km a week, 33 % bicycled more than 10 km a week, and 61 % were active in different kinds of sportclubs. Conclusion: Women informed about estrogentreatmentand issued prescription before discharge from hospital were highly compliant to treatment during 1-3 years observation. The populationis well informed about benefits and risks to HRT.
220
P336 STATUS AFTER
MP Everett. MG Hardicre, A WM Hay, CF Westmacott, *H Towers, JO Drife, MA Smith University Department of Obstetrics & Gynaecology Leeds General Infirmary, Leeds LS2 3EX United Kingdom *Schering Healthcare
HYSTEROSCOPIC RESECTION OF BENIGN INTRAUTERINE LESIONS IN POST-MENOPAUSAL WOMEN E Grassini. M Benfatti, C Bertulessi, L Iasi, G Radici, P Capetta, Fifth Department Obstetrics and Gynecology, University of Milan, Via M. Melloni 52,20129 Milan, Italy.
197 hysterectomised women were screened between March 1994 and September 1995 for inclusion in a clinical trial to test a new oestrogen patch. The principal inclusion criteria we were required to use were: Age 40-65 years; Hysterectomy (Hx); FSH >40 IU; Oestradiol (E2) cl10 pmol/L. 57 women failed to meet the entry criteria. Some of those excluded were probably post menopausal (PM) and this raises a question about the suitability of the biochemical parameters used for the entry criteria. 7 women aged 48-65, 9-33 years post Hx, with 25
Between January 1995 and December 1995, 101 post-menopausalwomen with Abnormal Uterine Bleeding (A.U.B.) underwent an office hysteroscopy at the Vth Department of Obstetrics and Gynecology of the University of Milan. 25 patients presented a benign pathology of uterine cavity subsequently excised with hysteroscopic resection under general anesthesia. The average age was 59.84 years (range: 46-79) and no patient previously taked Hormone Replacement Therapy. The average hospital stay was 2.20 days (range: 2-3). The average hospitalization postoperative time was 1.16 days (range l-2). The hystology showed 21 endometrial polyps, 2 submucous myomas, one polyp with associated myoma and one polyp with associated simple endometrial hyperpiasia In the following two months after surgery, no patient reported recurrence of A.U.B. The complete hysteroscopic resection of the benign lesions allows us to resolve the bleeding and in the same time to support the hystology in the exclusion of any malignant changes.
P337
P338
TUBAL LIGATION AND LONG TERM HEALTH OUTCOMES: RETROSPECTIVE INFORMATION IN THE MELBOURNE WOMEN’S MIDLIFE STUDY.
COMPLIANCE TO ESTROGEN TREATMENT AFI’ER HYSTERECTOMY AND BILATERAL OOPHORECTOMY, PATIENTS LIFESTYLE AND KNOWLEDGE OF HRT EFFECl-S.
JR Taffe, E C Dud& L Dennerstein, Key Centre for Women’s Health, The University of Melbourne, Carlton, 3053, Australia.
P H&e, Gynrekologisk - Obstetrisk afd. Centralsygehuset i Naestved, 4700 Niestved, Denmark
Tubal ligation has been shown in hospital based and huge epidemiological studies to be associated with negative health outcomes in the long term. In a population based sample of 2001 Australian born women aged 45-55 years, over 40% of women interviewed had had a tubal ligation, and retrospective data on the dates of tubal ligation, hysterectomy, oophorectcmy and other health outcomes are available. Odds ratios of hysterectomy estimated from logistic regression with tubal ligation as a categorical exposure and allowing for confounders do not differ significantly from 1. Similarly there is a lack of association of tubal ligation with other serious outcomes, or with indicators of present wellbeing such as the Affectometer scale and self rated health. In interpreting these results it must be borne in mind that follow-up times are censored at ages between 45 and 55.
Eighty-two of 88 women, aged40-55, retumed a questionnaire 1-3 y atler hysterectomy and bilateral oophorectomy. Indications; bleeding disorders and/or tibroma of the uterus. At discharge f?om the hospital they receiveda prescription: 2 mg estrogen daily treatment Ninety-five% bought the estrogen withii 3 days, 97% started treatment the same day, 94% choose tablets and 99% took one tablet daily. Eighty-two% stayed on the same treatment and 99% were compliant to the treatment during the observation period. Knowledge of HRT; 99% knew that HRT existed, primary source of information (63%) is newspapers/magazines, secondary (53%) general practitioners (GP). Ninety-six% knows that HRT can treat climacteric symptoms, 90% know the effect on bone and 33% know the pos. effect on cardiovascular disease. Sixty-nine% believe that HRT is a riskfactor for developing breast cancer and 50% believes it increases body weight. Seventy-four % believes that HRT increases the quality of life. Developing climacteric symptoms 85% would contact the GP for more information and treatment, however having no symptoms 82% would not contact the GP. Lifestyle issues; 68% were non-smokers, 24% combined estrogen treatment with a natural medicine, 68% took a vitamin preparation 86% of which included calcium. Only 21 % drank more than half a liter milk daily. Seven%jogged more than 5 km a week, 33 % bicycled more than 10 km a week, and 61 % were active in different kinds of sportclubs. Conclusion: Women informed about estrogentreatmentand issued prescription before discharge from hospital were highly compliant to treatment during 1-3 years observation. The populationis well informed about benefits and risks to HRT.
220