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P63. Positron Emission Tomography – A third eye to solve mystery
S94
Abstracts / Oral Oncology 47 (2011) S74–S156
revealed malignancy, representing 66.7% of all specimens, which included five cases of squamous cell carcinoma, two cases of verrucous carcinoma, and a case of squamous cell carcinoma in situ. Discussion: Despite benign report in initial incisional biopsy, the risk of malignancy after complete excision was 66.7% in this series. Because leukoplakia is a superficial lesion, excision with 1 cm margin was acceptable in all patients. Complete excision seems to be a safer management strategy for leukoplakia of the lateral tongue than to wait and see with regular follow-up.
imaging modalities are used to investigate oral cancer, in this Cone Beam Computed Tomography performs the task accurately to see all the structures in three dimensions. Thus it provides the extent of lesion in all sides which will be useful for surgical procedures. The Cone Beam Computed Tomography combines conventional ray with computerized volumetric three-dimensional images by single rotation to acquire a series of projections. This paper intends to highlight the necessity of Cone Beam Computed Tomography to rule out the extent of an oral cancerous lesion and structures involved.
doi:10.1016/j.oraloncology.2011.06.303 doi:10.1016/j.oraloncology.2011.06.305 P61. N0 tongue cancer and cervical lymph node metastasis R. Asano*, T. Onituka, Y. Iida, T. Kamijyo, D. Mochizuki Shizuoka Cancer Center Hospital, Japan Object: Control of latent lymph node metastasis is issue in N0 cancers of the tongue. In our department, we administer neck dissection in tumor infiltrative thickness. Methods: Retrospective study: From September 2002 to September 2009, N0 cancer of the tongue 127 cases. Male: 81; female: 46 ages from 18 to 88, median 66 years old. The terms of observation were from 1 to 9 years, median 5 years. In these cases, all of them were first time treatment in our department. Some cases ware treated partial resection of the tongue alone (group A); others were added prophylactic neck dissection contemporary (group B). Results: Pathological diagnosis, squamous cell carcinoma was 115 cases. And the rest of them were five cases of verrucous carcinoma, five cases of CIS, two cases of Acantholytic SCC. One hundred cases were group A, treated partial resection of the tongue alone and watch policy. T classification T1:63 T2:36 T3:1. In group A, metastasis of the lymph node occurred 25 cases, and neck dissection was performed. Twenty-seven cases were group B.T classification T1:1 T2:17 T3:5 T4:4. In group B, five cases proved lymph node metastasis at pathological diagnosis. T classification T2:3 T3:1 T4:1. All of N0 cases, 30 cases were lymph node metastasis. Latent lymph node metastasis rate: 23.6%. Result of tumor infiltrative thickness in T1 cases, lymph node metastasis occurred 3.4% under 4 mm group. 47.6% in group of 4 mm and over proved lymph node metastasis. In T2 cases, no cases were lymph node metastasis less than 4 mm group. 37.8% in group of 4 mm and over proved lymph node metastasis. No difference of survival rate between groups A and B. Conclusions: Latent lymph node metastasis rate: 23.6%. More than 4 mm tumor infiltrative thickness was T1:47.6%, T2:37.8%, respectively. In T1/2 cases, we measure tumor thickness at echography or magnetic resonance imaging before operation. If thickness was less than 4 mm, prophylactic neck dissection will not be performed. More than 4 mm thickness tumor cases, we inform no difference of survival rate between groups A and B, and latent lymph node metastasis rate to patient. And we discuss about indication of neck dissection with patient considering age, social circumstance and so on.
P63. Positron Emission Tomography – A third eye to solve mystery T. Vijayavel * , S.-C. Selvamuthukumar Sree Balaji Dental College & Hospital, India Positron Emission Tomography (PET) is a modern, advanced diagnostic imaging technique in which radiopharmaceuticals are administrated intravenously and the resultant gamma rays generated from the target tissue is captured and studied. This image helps to identify peripheral infiltration, multiple involvement of neoplasm, extension of neoplasm in different directions and also whether the neoplasm originates from soft tissue, hard tissue or both. This imaging is advantageous in detecting the early lesion before it manifests clinically. Thus it helps in early diagnosis, thereby better prognosis. The present paper highlights the uses of Positron Emission Tomography in oral and maxillofacial region. doi:10.1016/j.oraloncology.2011.06.306
P64. Follicular dendritic cell sarcoma of the tonsil Y.-G. Eun *,a, D.-H. Chung b, K.-H. Kwon b a b
Sugkyunkwan University Samsung Chanwon Hospital, Republic of Korea Kyung Hee University, Republic of Korea
Follicular dendritic cell sarcoma (FDCS) is unusual, and those with an extranodal origin in the head and neck region are extremely rare. To date, no cases of tumors featuring the characteristics of follicular dendritic cells were reported in Korea. We report a new case of FDCS of the tonsils in a 65-year-old man. A diagnostic tonsillectomy was performed. Based on histopathologic and immunohistochemical findings, the patient was diagnosed with FDCS. Adjuvant radiotherapy was performed due to a high mitotic count. The patient survived with a 2-year disease free period. The differential diagnosis of a tonsillar mass must include FDCS. In cases in which FDCS is suspected on histopathologic examination, an immunohistochemical study is essential for the diagnosis.
doi:10.1016/j.oraloncology.2011.06.304 doi:10.1016/j.oraloncology.2011.06.307 P62. The task of Cone Beam Computed Tomography in oral cancer S. Mohamed Anser*, S.-C. Selvamuthukumar Sree Balaji Dental College & Hospital, India Cancer is one of the major threats to public health in the developed country and increasingly in the developing country. Various
P65. A 10 year clinicopathological study of 74 cases of keratocystic odontogenic tumour P.-S. Satheeshkumar*, A. Balan Department of Oral Medicine and Radiology, Government Dental College, Trivandrum, Kerala, India
Abstracts / Oral Oncology 47 (2011) S74–S156
revealed malignancy, representing 66.7% of all specimens, which included five cases of squamous cell carcinoma, two cases of verrucous carcinoma, and a case of squamous cell carcinoma in situ. Discussion: Despite benign report in initial incisional biopsy, the risk of malignancy after complete excision was 66.7% in this series. Because leukoplakia is a superficial lesion, excision with 1 cm margin was acceptable in all patients. Complete excision seems to be a safer management strategy for leukoplakia of the lateral tongue than to wait and see with regular follow-up.
imaging modalities are used to investigate oral cancer, in this Cone Beam Computed Tomography performs the task accurately to see all the structures in three dimensions. Thus it provides the extent of lesion in all sides which will be useful for surgical procedures. The Cone Beam Computed Tomography combines conventional ray with computerized volumetric three-dimensional images by single rotation to acquire a series of projections. This paper intends to highlight the necessity of Cone Beam Computed Tomography to rule out the extent of an oral cancerous lesion and structures involved.
doi:10.1016/j.oraloncology.2011.06.303 doi:10.1016/j.oraloncology.2011.06.305 P61. N0 tongue cancer and cervical lymph node metastasis R. Asano*, T. Onituka, Y. Iida, T. Kamijyo, D. Mochizuki Shizuoka Cancer Center Hospital, Japan Object: Control of latent lymph node metastasis is issue in N0 cancers of the tongue. In our department, we administer neck dissection in tumor infiltrative thickness. Methods: Retrospective study: From September 2002 to September 2009, N0 cancer of the tongue 127 cases. Male: 81; female: 46 ages from 18 to 88, median 66 years old. The terms of observation were from 1 to 9 years, median 5 years. In these cases, all of them were first time treatment in our department. Some cases ware treated partial resection of the tongue alone (group A); others were added prophylactic neck dissection contemporary (group B). Results: Pathological diagnosis, squamous cell carcinoma was 115 cases. And the rest of them were five cases of verrucous carcinoma, five cases of CIS, two cases of Acantholytic SCC. One hundred cases were group A, treated partial resection of the tongue alone and watch policy. T classification T1:63 T2:36 T3:1. In group A, metastasis of the lymph node occurred 25 cases, and neck dissection was performed. Twenty-seven cases were group B.T classification T1:1 T2:17 T3:5 T4:4. In group B, five cases proved lymph node metastasis at pathological diagnosis. T classification T2:3 T3:1 T4:1. All of N0 cases, 30 cases were lymph node metastasis. Latent lymph node metastasis rate: 23.6%. Result of tumor infiltrative thickness in T1 cases, lymph node metastasis occurred 3.4% under 4 mm group. 47.6% in group of 4 mm and over proved lymph node metastasis. In T2 cases, no cases were lymph node metastasis less than 4 mm group. 37.8% in group of 4 mm and over proved lymph node metastasis. No difference of survival rate between groups A and B. Conclusions: Latent lymph node metastasis rate: 23.6%. More than 4 mm tumor infiltrative thickness was T1:47.6%, T2:37.8%, respectively. In T1/2 cases, we measure tumor thickness at echography or magnetic resonance imaging before operation. If thickness was less than 4 mm, prophylactic neck dissection will not be performed. More than 4 mm thickness tumor cases, we inform no difference of survival rate between groups A and B, and latent lymph node metastasis rate to patient. And we discuss about indication of neck dissection with patient considering age, social circumstance and so on.
P63. Positron Emission Tomography – A third eye to solve mystery T. Vijayavel * , S.-C. Selvamuthukumar Sree Balaji Dental College & Hospital, India Positron Emission Tomography (PET) is a modern, advanced diagnostic imaging technique in which radiopharmaceuticals are administrated intravenously and the resultant gamma rays generated from the target tissue is captured and studied. This image helps to identify peripheral infiltration, multiple involvement of neoplasm, extension of neoplasm in different directions and also whether the neoplasm originates from soft tissue, hard tissue or both. This imaging is advantageous in detecting the early lesion before it manifests clinically. Thus it helps in early diagnosis, thereby better prognosis. The present paper highlights the uses of Positron Emission Tomography in oral and maxillofacial region. doi:10.1016/j.oraloncology.2011.06.306
P64. Follicular dendritic cell sarcoma of the tonsil Y.-G. Eun *,a, D.-H. Chung b, K.-H. Kwon b a b
Sugkyunkwan University Samsung Chanwon Hospital, Republic of Korea Kyung Hee University, Republic of Korea
Follicular dendritic cell sarcoma (FDCS) is unusual, and those with an extranodal origin in the head and neck region are extremely rare. To date, no cases of tumors featuring the characteristics of follicular dendritic cells were reported in Korea. We report a new case of FDCS of the tonsils in a 65-year-old man. A diagnostic tonsillectomy was performed. Based on histopathologic and immunohistochemical findings, the patient was diagnosed with FDCS. Adjuvant radiotherapy was performed due to a high mitotic count. The patient survived with a 2-year disease free period. The differential diagnosis of a tonsillar mass must include FDCS. In cases in which FDCS is suspected on histopathologic examination, an immunohistochemical study is essential for the diagnosis.
doi:10.1016/j.oraloncology.2011.06.304 doi:10.1016/j.oraloncology.2011.06.307 P62. The task of Cone Beam Computed Tomography in oral cancer S. Mohamed Anser*, S.-C. Selvamuthukumar Sree Balaji Dental College & Hospital, India Cancer is one of the major threats to public health in the developed country and increasingly in the developing country. Various
P65. A 10 year clinicopathological study of 74 cases of keratocystic odontogenic tumour P.-S. Satheeshkumar*, A. Balan Department of Oral Medicine and Radiology, Government Dental College, Trivandrum, Kerala, India