Pain threshold in unilateral migraine

s73

BUPRENORPHINE OPERATIVE

VS MORPHINE

BOTH SPINALLY

PAIN RELIEF.2S;Valenti'

INJECTED

*Inst.Anesthesiology

and Intensive

Care,Padova,

Aim of investigation:Opioids(OP)spinally association

Bianchi.*jm di Livenza,

, Dept.Anesth.Hosp.Motta

E.Vincenti**,G.P.Giron

AND POST-

,A.Segatto*tE.De

ITALY

administered

with Local Anaesthetics(LA)produce

than LA alone during postoperative

period.

a better

Morphine(M

before

However,

in some patients.

Buprenorphine(BPN)

in

action

the most used OP

its use causes some side effects

for this purpose.

surgery

analgesic

such as itching

is considered

an alternative

was carried

out on 4 groups

OP, but

the ideal dose is not clear yet. Methods:The

clinical

gical patients

spinal administration received

M;the

respectively

0,0015

and 0,003O

minutes

Nausea/Vomiting Itching urinary

Conclusions:Our to 0,007 mg.kg-1

Bupivacaine(BP)(25

group);the

second

mg.kg-lof

of total pain relief

Results:

Retention

schedule),all

first group

in addition

with 0,007 to the LA

time(in minutesjwas

the end of the surgery.

IDgroup

IIOgroup

IIIOgroup

IVOgroup

524 + 398

1329 + 270

740 + 481

1290 + 396

6 _-

30%

9

45% suggest

results

of M spinally

but a lower incidence

mg).The

BPN. Analgesia

following

of 20 sur -

were given by

one was also treated

third and the fourth ones received

as period

Analgesia

to a randomized

1% hyperbaric

only BP(contro1

mg.kg-'of defined

investigation

eachcaccording

3

5

25%

4

20%

10

50%

-

-

9

45%

9 8 40% 45% mg.kg-1 OF BPN in comparison

that O,OQ30

injected

of side effects

produce

the same analgesic

in postoperative

15%

time

,

period.

Headache PAIN THRESHOLD IN UNILATERAL MIGRAINE. G. Nattero.G. Allais*,L. Biale*.C. De Lorenzo*.Dept. of Biomedicine. HeadacheCenter, Universityof Turin, Turin, Italy. Aim of Investigation: Lateralization,one of the most peculiar feature of the migraine syndrome, is inborn in the term migraine. It is well known that some migrainous patients suffer only from typical unilateral migraine crises during their whole lifetime. Up to now there is no agreement among Authors on a definite explanation for this phenomenon. Aim of our study was to evaluate the possible differences in the pain threshold between the two sides of the patient's head and to see if this difference is a typical feature of the migraineur in the headache-free periods. methods: 30 patients were examined, on the basis of the Ad Hoc Coaaaitteeon Headache Classification 6 suffered from classic and 24 from cormionmigraine. Criteria for admission were: 1) Mono and ipsilateral pain crises; 2) a frequency of 4 crises a month at the most; 3) no medication allowed; 4) no head injury. The measurement of pain threshold was done bilaterally on the patient's forehead skin, 2 cm from the nose root, by means of 2 silver electrodes. A 300 Hz train of square wave pulses of 2Omsec duration was used. Measurements were done 3 times in a 20 days period, always in basal conditions, and 72 hours at least after the previous attack in order to ensure a pain threshold measurement free from any painful sequelae. Moreover, MMPI, BDI and STAI Xl-2 were administered to every patient to perform personality assessment and exclude any anxious or depressive components. Results: The pain-affected side showed a pain threshold significantlylower when compared to the unaffected area (p