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Paper Electrophoresis
316
BOOK REVIEWS
imperfect response of the general adapta tion syndrome plays the major role. Adapta tion manifests two phases, or sometimes three, consisting of the alarm reaction (adrenocortical enlargement, thymicolymphatic atrophy, and loss of weight), the stage of resistance and—if this is inade quate—the stage of exhaustion. Stress, ap plied in moderation, is necessary for life. Everyone must experience the first two stages again and again ; otherwise man would never become adapted to perform the activi ties and resist the injuries and infections which are his lot. Selye envisions far-reaching philosophic implications. " T h e incitement, by our actions, of gratitude in others is most likely to assure our security within society. W h y not seek this consciously as a long-range aim in life?" T h e jacket contains the following state ment : " H e r e , in language easily understand able by the general reader, the man who has been called 'the Einstein of Medicine' ex plains his stress concept." Since this book was intended for both layman and scientist, the repeated use of arbitrary abbreviations should have been avoided. James E . Lebensohn. J . A . M . A . Q U E R I E S AND M I N O R N O T E S .
St.
Louis, C. V. Mosby, 1956. (Published for the American Medical Association.) 334 pages. P r i c e : $5.50. The column entitled "Queries and minor notes" appearing in the Journal of the American Medical Association has long been popular with readers and some of the more interesting items have been reprinted in this book. T h e material is arranged and indexed according to the Standard Nomen clature of Diseases and Operations so that one can find the material in any special field without difficulty. Twenty-six items on the eye are included, ranging from "After image in color-blind persons" to "Xanthopia following snake bite."
The intriguing thing about this feature in the J.A.M.A. is the fact that the questions are those submitted by practicing physicians (name usually signed) who have been unable to find the answer to their particular prob lems and that the answers are by competent authorities, who, by A.M.A. policy, are anonymous. It would add further interest and authority if the replies were signed. Since many of the questions raised are unique the book becomes of interest, not as a textbook, but as an interesting means of acquiring information on little-known sub jects. William A. Mann. P A P E R ELECTROPHORESIS.
Ciba Foundation
Symposium. Edited by G. E. W . Wolstenhome and E. C. P . Millar. Boston, Little, Brown & Company, 1956. 224 pages, 74 illustrations, index. Price : $6.75. Paper electrophoretic technique has be come an increasingly important diagnostic tool. In this volume the world's leading experts in this field detail the methods of paper electrophoresis and their use in medi cal and biochemical problems. Electrophore sis on filter paper is a simple alternative to the complicated procedure of free electro phoresis introduced by Tiselius in 1937 and has many advantages over the latter. Paper electrophoresis permits the simultaneous analysis, in the same sample, of proteins, lipids, and the protein-bound carbohydrates, and, by staining and other means, various substances which are part of the protein can also be determined. About 4,000 reports have been published dealing with the manifold applications of paper electrophoresis, includ ing a notable number relating to the bio chemistry of the eye. Since 1949 the Ciba Foundation has spon sored five or six such symposia annually; and 20 specialized volumes such as this have been published to date. James E. Lebensohn.
BOOK REVIEWS
imperfect response of the general adapta tion syndrome plays the major role. Adapta tion manifests two phases, or sometimes three, consisting of the alarm reaction (adrenocortical enlargement, thymicolymphatic atrophy, and loss of weight), the stage of resistance and—if this is inade quate—the stage of exhaustion. Stress, ap plied in moderation, is necessary for life. Everyone must experience the first two stages again and again ; otherwise man would never become adapted to perform the activi ties and resist the injuries and infections which are his lot. Selye envisions far-reaching philosophic implications. " T h e incitement, by our actions, of gratitude in others is most likely to assure our security within society. W h y not seek this consciously as a long-range aim in life?" T h e jacket contains the following state ment : " H e r e , in language easily understand able by the general reader, the man who has been called 'the Einstein of Medicine' ex plains his stress concept." Since this book was intended for both layman and scientist, the repeated use of arbitrary abbreviations should have been avoided. James E . Lebensohn. J . A . M . A . Q U E R I E S AND M I N O R N O T E S .
St.
Louis, C. V. Mosby, 1956. (Published for the American Medical Association.) 334 pages. P r i c e : $5.50. The column entitled "Queries and minor notes" appearing in the Journal of the American Medical Association has long been popular with readers and some of the more interesting items have been reprinted in this book. T h e material is arranged and indexed according to the Standard Nomen clature of Diseases and Operations so that one can find the material in any special field without difficulty. Twenty-six items on the eye are included, ranging from "After image in color-blind persons" to "Xanthopia following snake bite."
The intriguing thing about this feature in the J.A.M.A. is the fact that the questions are those submitted by practicing physicians (name usually signed) who have been unable to find the answer to their particular prob lems and that the answers are by competent authorities, who, by A.M.A. policy, are anonymous. It would add further interest and authority if the replies were signed. Since many of the questions raised are unique the book becomes of interest, not as a textbook, but as an interesting means of acquiring information on little-known sub jects. William A. Mann. P A P E R ELECTROPHORESIS.
Ciba Foundation
Symposium. Edited by G. E. W . Wolstenhome and E. C. P . Millar. Boston, Little, Brown & Company, 1956. 224 pages, 74 illustrations, index. Price : $6.75. Paper electrophoretic technique has be come an increasingly important diagnostic tool. In this volume the world's leading experts in this field detail the methods of paper electrophoresis and their use in medi cal and biochemical problems. Electrophore sis on filter paper is a simple alternative to the complicated procedure of free electro phoresis introduced by Tiselius in 1937 and has many advantages over the latter. Paper electrophoresis permits the simultaneous analysis, in the same sample, of proteins, lipids, and the protein-bound carbohydrates, and, by staining and other means, various substances which are part of the protein can also be determined. About 4,000 reports have been published dealing with the manifold applications of paper electrophoresis, includ ing a notable number relating to the bio chemistry of the eye. Since 1949 the Ciba Foundation has spon sored five or six such symposia annually; and 20 specialized volumes such as this have been published to date. James E. Lebensohn.