Papers on combinatorial chemistry or solid-phase synthesis from other journals - May 2000

Papers on combinatorial chemistry or solid-phase synthesis from other journals – May 2000 Rolling loop scan: an approach featuring ring-closing metathesis for generating libraries of peptides with molecular shapes mimicking bioactive conformations or local folding of peptides and proteins. Reichwein, J.F.; Wels, B.; Kruijtzer, J.A.W.; Versluis, C.; Liskamp, R.M.J. Angew. Chem., Int. Ed. (1999), 38(24), 3684-3687. An ARE-selective DNA minor groove binder from a combinatorial approach. Hamy, F.; Albrecht, G.; Florsheimer, A.; Bailly, C. Biochem. Biophys. Res. Commun. (2000), 270(2), 393-399. Soluble-polymer-supported synthesis of β-lactams on a modified poly(ethylene glycol). Annunziata, R.; Benaglia, M.; Cinquini, M.; Cozzi, F. Chem. Eur. J. (2000), 6(1), 133138. A facile solid-phase strategy for the synthesis of oligonucleotide-tetraphenylporphyrin conjugates. De Napoli, L.; De Luca, S.; Di Fabio, G.; Messere, A.; Montesarchio, D.; Morelli, G.; Piccialli, G.; Tesauro, D. Eur. J. Org. Chem. (2000), (6), 1013-1018. Solid-phase synthesis and structural analysis of bicyclic β-turn mimetics incorporating functionality at the i to i + 3 positions. Eguchi, M.; Lee, M.S.; Nakanishi, H.; Stasiak, M.; Lovell, S.; Kahn, M. J. Am. Chem. Soc. (1999), 121(51), 12204-12205. Substrate specificity and inhibition studies of human serotonin N-acetyltransferase. Ferry, G.; Loynel, A.; Kucharczyk, N.; Bertin, S.; Rodriguez, M.; Delagrange, P.; Galizzi, J.-P.; Jacoby, E.; Volland, J.-P.; Lesieur, D.; Renard, P.; Canet, E.; Fauchere, J.-L.; Boutin, J.A. J. Biol. Chem. (2000), 275(12), 8794-8805. Preparation of an amine N-oxide on solid phase: an efficient promoter of the PausonKhand reaction. Kerr, W.J.; Lindsay, D.M. JCS Chem. Commun. (1999), (24), 25512552. Single-bead structure elucidation. Requirements for analysis of combinatorial solid-phase libraries by Nanoprobe MAS-NMR spectroscopy. Gotfredsen, C.H.; Grotli, M.; Willert, M.; Meldal, M.; Duus, J.O. JCS Perkin Trans. 1 (2000), (7), 1167-1171. Efficient solid-phase synthesis of regioregular head-to-tail-coupled oligo(3alkylthiophene)s up to a dodecamer. Kirschbaum, T.; Briehn, C.A.; Bauerle, P. JCS Perkin Trans. 1 (2000), (8), 1211-1216. Comparative study of reductive amination reaction on 5-(4-formyl-3,5dimethoxyphenoxy)valeric acid and its monomethoxy analog using the Multipin approach. Bui, C.T.; Bray, A.M.; Pham, Y.; Campbell, R.; Ercole, F.; Rasoul, F.A.; Maeji, N.J. Mol. Diversity (2000), 4(3), 155-163.

Solid phase synthesis of hydantoins by thermal cyclization and screening of reaction conditions using APOS 1200. Karnbrock, W.; Deeg, M.; Gerhardt, J.; Rapp, W. Mol. Diversity (2000), 4(3), 165-171. Use of combinatorial library screening to identify inhibitors of a bacterial two-component signal transduction kinase. Roychoudhury, S.; Blondelle, S.E.; Collins, S.M.; Davis, M.C.; McKeever, H.D.; Houghten, R.A.; Parker, C.N. Mol. Diversity (2000), 4(3), 173182. Synthesis of peptidomimetics using a polymer-bound Boc-linker. Redemann, T.; Bandel, H.; Jung, G. Mol. Diversity (2000), 4(3), 191-197. Comparative conformational analysis of peptide libraries. Jacchieri, S.G. Mol. Diversity (2000), 4(3), 199-207. Novel hydrazino-carbonyl-amino-methylated polystyrene (HCAM) resin methodology for the synthesis of P1-aldehyde protease inhibitor candidates. Siev, D.V.; Semple, J.E. Org. Lett. (2000), 2(1), 19-22. Combinatorial target-guided ligand assembly: identification of potent subtype-selective cSrc inhibitors. Maly, D.J.; Choong, I.C.; Ellman, J.A. Proc. Natl. Acad. Sci. USA. (2000), 97(6), 2419-2424. A novel approach to the solid-phase synthesis of (acyloxy)methyl ketones. Mujica, M.T.; Jung, G. Synlett (1999), (12), 1933-1935. © 2000 Elsevier Science Inc. All rights reserved.