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Parkinson's disease and chronic insomnia disorder
S162
Abstracts/Sleep Medicine 16 (2015) S2–S199
are important, especially for temporary psycho-biological insomnia. Materials and methods: Systemic presentation of the principles and methods of operation of insomnia non-drugs therapies, including Chinese medicine physical therapies: acupuncture, massages; modern physical therapies: magnetic therapy, light therapy; psychotherapies: cognitive behavioral therapy (CBT), Morita therapy, psychoanalysis, flotation therapy, relaxing therapy, suggestion and hypnosis therapy, music therapy; Chinese medicine traditional psychotherapy: emotional mutual control therapy; Chinese medicine modern psychotherapy: Thought Imprint Psychotherapy in a lowered resistance state (TIP). Results: Among insomnia non-drugs therapy, CBT shows credible results and obtain the approval of the American Psychological Association. Nowadays, it is already the most common used and the most efficient non-drugs therapy against insomnia. Conclusion: non-drugs therapies can avoid the worsening of insomnia, reduce the quantity of drugs taken and reduce drugs dependence and side effects. Following the transformation of the medical model, non-drugs therapies are becoming a focal point of the medical profession. Acknowledgements: Thanks to the support of Key Projects in the National Science & Technology Pillar Program during the Twelfth Five-Year Plan Period (2014BAI10B07), National Natural Science Foundation of China (81373772). http://dx.doi.org/10.1016/j.sleep.2015.02.1533
Chinese medicine treatment of hypnotics-dependent insomnia Z. Xuanzi, W. Fang, W. Weidong Beijing University of Chinese Medicine, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, China
Introduction: These past years, hypnotics-dependent insomnia is becoming more and more common; Western medicine drugs substitution therapy is effective but presents potential risks, and more and more specialists are starting to look for Chinese medicine treatment. Materials and methods: Presenting the main methods of treating hypnotics-dependent insomnia with Chinese medicine. (1) Chinese medicine drugs: Mr. Sun divides hypnotics-dependent insomnia into three groups: intern phlegm heat, liver qi congestion and insufficiency of qi and yin, treating respectively with Huang Lian Wen Dan Tang, Dan Zhi Xiao Yao San and Sheng Mai San. (2) Acupuncture: Mr. Sun and others puncture mainly baihui (DU20), fengchi (GB20), tianzhu (BL10) and naokong (GB19), etc. (3) Tuina massages: Mr. Li uses Tuina techniques to treat hypnoticsdependent insomnia, using mainly baihui (DU20), touwei (ST8), yintang (EX-HN3) and sishencong (EX-HN1), etc. The techniques used are Yizhi chan, kai tianmen, etc. (4) Chinese medicine psychotherapy: Ms. Wang on the basis of Mr. Wang’s TIP sleep regulation technique considered the hypnotics reduction process and created a TIP drug reduction technique used specially to reduce the use of hypnotics. It includes cognitive drug-reducing method, substitution drug-reducing method and symptomatic drug-reducing method. Results: Chinese medicine drugs, acupuncture, Tuina massages and Chinese medicine psychotherapy are the main therapies used by Chinese medicine to treat hypnotics-dependent insomnia and all have some efficacy. Among them Mr. Zhang discovered that acupuncture could inhibit REM sleep rebound, maintain and increase slow wave sleep, regulate autonomic nervous system and have some placebo-like effects.
Conclusion: In all the above reports no serious side-effects were observed. Comparatively with Western medicine drugs, Chinese medicine probably is safer and more easily accepted by patient to treat hypnotics-dependent insomnia. Acknowledgements: Thanks to Pr. Sun Zenghua, Pr. Zhang Yue, Pr. Li Peihong, Pr. Wang Weidong and Dr. Wang Fang for their research on Chinese medicine treatments of hypnotics-dependent insomnia. http://dx.doi.org/10.1016/j.sleep.2015.02.1534
Parkinson’s disease and chronic insomnia disorder A. Ylikoski 1, K. Martikainen 2, M. Partinen 1 1 Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland 2 Finnish Parkinson Association, The Finnish Parkinson Foundation, Turku, Finland
Introduction: Various sleep related complications are common in Parkinson’s disease (PD). The prevalence of chronic insomnia disorder (ICD-10) and its association with other symptoms were studied. Materials and methods: Altogether 1447 Parkinson patients, aged 43–89 years, participated in a questionnaire study. The response rate was 59.0% and of these 80.8% had answered to all questions used in the analyses (N = 689). Results: Prevalence of insomnia was 36.8% (95% CI 33.3–40.5). Difficulty initiating sleep (≥3 evenings per week) was 18.0% (95% CI 15.1–20.9), disrupted sleep (≥3 nights per week) 81.54% (78.5– 84.4), frequent awakening during the night (≥3 nights per night) 31.3% (27.8–34.8), early morning awakening (≥3 mornings per week) 40.4% (36.8–44.1) and non-restorative sleep (at least over the last month) 38.5% (34.8–42.1). Young age, female gender, early onset of PD and longer duration of PD are more common in patients with insomnia than in patients without insomnia. In adjusted logistic regression model, chronic insomnia (OR 2.49; 95% CI 1.75–3.53) and REM behavior sleep disorder (1.78; 1.26–2.50) were significantly associated to poor quality of life (WHO5 <13). Conclusion: Occurrence of insomnia according to ICD-10 in patients with PD is more common than previously reported prevalences of insomnia disorder in general population. The most common insomnia symptoms reported by PD patients were sleep fragmentation, early awakenings and non-restorative sleep. Acknowledgements: This study was supported by the Finnish Parkinson Foundation. We thank Anne Huutoniemi and Juuso Kosonen for helping the data entry, and Hannele Laakso for linguistic help. http://dx.doi.org/10.1016/j.sleep.2015.02.1535
Validation of Chinese version of structured diagnostic interview for insomnia disorder: A preliminary report W. Yu, J. Zhang, Y. Wing The Chinese University of Hong Kong, Hong Kong
Introduction: Objectives: The Diagnostic Interview for Sleep Patterns and Disorders (DISP) has been shown to have satisfactory psychometric property to determine the diagnoses of various common sleep disorders. This study aimed to validate the Chinese version of DISP in differentiating patients with and without lifetime insomnia disorder. Materials and methods: The translation and back-translation of DISP were conducted under the standardized protocol. The consecutive patients with various sleep disorders attending sleep
Abstracts/Sleep Medicine 16 (2015) S2–S199
are important, especially for temporary psycho-biological insomnia. Materials and methods: Systemic presentation of the principles and methods of operation of insomnia non-drugs therapies, including Chinese medicine physical therapies: acupuncture, massages; modern physical therapies: magnetic therapy, light therapy; psychotherapies: cognitive behavioral therapy (CBT), Morita therapy, psychoanalysis, flotation therapy, relaxing therapy, suggestion and hypnosis therapy, music therapy; Chinese medicine traditional psychotherapy: emotional mutual control therapy; Chinese medicine modern psychotherapy: Thought Imprint Psychotherapy in a lowered resistance state (TIP). Results: Among insomnia non-drugs therapy, CBT shows credible results and obtain the approval of the American Psychological Association. Nowadays, it is already the most common used and the most efficient non-drugs therapy against insomnia. Conclusion: non-drugs therapies can avoid the worsening of insomnia, reduce the quantity of drugs taken and reduce drugs dependence and side effects. Following the transformation of the medical model, non-drugs therapies are becoming a focal point of the medical profession. Acknowledgements: Thanks to the support of Key Projects in the National Science & Technology Pillar Program during the Twelfth Five-Year Plan Period (2014BAI10B07), National Natural Science Foundation of China (81373772). http://dx.doi.org/10.1016/j.sleep.2015.02.1533
Chinese medicine treatment of hypnotics-dependent insomnia Z. Xuanzi, W. Fang, W. Weidong Beijing University of Chinese Medicine, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, China
Introduction: These past years, hypnotics-dependent insomnia is becoming more and more common; Western medicine drugs substitution therapy is effective but presents potential risks, and more and more specialists are starting to look for Chinese medicine treatment. Materials and methods: Presenting the main methods of treating hypnotics-dependent insomnia with Chinese medicine. (1) Chinese medicine drugs: Mr. Sun divides hypnotics-dependent insomnia into three groups: intern phlegm heat, liver qi congestion and insufficiency of qi and yin, treating respectively with Huang Lian Wen Dan Tang, Dan Zhi Xiao Yao San and Sheng Mai San. (2) Acupuncture: Mr. Sun and others puncture mainly baihui (DU20), fengchi (GB20), tianzhu (BL10) and naokong (GB19), etc. (3) Tuina massages: Mr. Li uses Tuina techniques to treat hypnoticsdependent insomnia, using mainly baihui (DU20), touwei (ST8), yintang (EX-HN3) and sishencong (EX-HN1), etc. The techniques used are Yizhi chan, kai tianmen, etc. (4) Chinese medicine psychotherapy: Ms. Wang on the basis of Mr. Wang’s TIP sleep regulation technique considered the hypnotics reduction process and created a TIP drug reduction technique used specially to reduce the use of hypnotics. It includes cognitive drug-reducing method, substitution drug-reducing method and symptomatic drug-reducing method. Results: Chinese medicine drugs, acupuncture, Tuina massages and Chinese medicine psychotherapy are the main therapies used by Chinese medicine to treat hypnotics-dependent insomnia and all have some efficacy. Among them Mr. Zhang discovered that acupuncture could inhibit REM sleep rebound, maintain and increase slow wave sleep, regulate autonomic nervous system and have some placebo-like effects.
Conclusion: In all the above reports no serious side-effects were observed. Comparatively with Western medicine drugs, Chinese medicine probably is safer and more easily accepted by patient to treat hypnotics-dependent insomnia. Acknowledgements: Thanks to Pr. Sun Zenghua, Pr. Zhang Yue, Pr. Li Peihong, Pr. Wang Weidong and Dr. Wang Fang for their research on Chinese medicine treatments of hypnotics-dependent insomnia. http://dx.doi.org/10.1016/j.sleep.2015.02.1534
Parkinson’s disease and chronic insomnia disorder A. Ylikoski 1, K. Martikainen 2, M. Partinen 1 1 Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland 2 Finnish Parkinson Association, The Finnish Parkinson Foundation, Turku, Finland
Introduction: Various sleep related complications are common in Parkinson’s disease (PD). The prevalence of chronic insomnia disorder (ICD-10) and its association with other symptoms were studied. Materials and methods: Altogether 1447 Parkinson patients, aged 43–89 years, participated in a questionnaire study. The response rate was 59.0% and of these 80.8% had answered to all questions used in the analyses (N = 689). Results: Prevalence of insomnia was 36.8% (95% CI 33.3–40.5). Difficulty initiating sleep (≥3 evenings per week) was 18.0% (95% CI 15.1–20.9), disrupted sleep (≥3 nights per week) 81.54% (78.5– 84.4), frequent awakening during the night (≥3 nights per night) 31.3% (27.8–34.8), early morning awakening (≥3 mornings per week) 40.4% (36.8–44.1) and non-restorative sleep (at least over the last month) 38.5% (34.8–42.1). Young age, female gender, early onset of PD and longer duration of PD are more common in patients with insomnia than in patients without insomnia. In adjusted logistic regression model, chronic insomnia (OR 2.49; 95% CI 1.75–3.53) and REM behavior sleep disorder (1.78; 1.26–2.50) were significantly associated to poor quality of life (WHO5 <13). Conclusion: Occurrence of insomnia according to ICD-10 in patients with PD is more common than previously reported prevalences of insomnia disorder in general population. The most common insomnia symptoms reported by PD patients were sleep fragmentation, early awakenings and non-restorative sleep. Acknowledgements: This study was supported by the Finnish Parkinson Foundation. We thank Anne Huutoniemi and Juuso Kosonen for helping the data entry, and Hannele Laakso for linguistic help. http://dx.doi.org/10.1016/j.sleep.2015.02.1535
Validation of Chinese version of structured diagnostic interview for insomnia disorder: A preliminary report W. Yu, J. Zhang, Y. Wing The Chinese University of Hong Kong, Hong Kong
Introduction: Objectives: The Diagnostic Interview for Sleep Patterns and Disorders (DISP) has been shown to have satisfactory psychometric property to determine the diagnoses of various common sleep disorders. This study aimed to validate the Chinese version of DISP in differentiating patients with and without lifetime insomnia disorder. Materials and methods: The translation and back-translation of DISP were conducted under the standardized protocol. The consecutive patients with various sleep disorders attending sleep