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BOOK REVIEWS
embryology and developmental anomalies may be confusing. The guide to specimen examination is clear and well illustrated and an excellent practical guide for novices in this area. The third and largest section gives an excellent guide. organ fystern by organ system, to the types of abnormalities that may be diagnosed in these fetuses. They illustrate and discuss in practical terms the large range of diseases which may be detected. A realistic range ot iiilrauterine infections, chromosome and developmental abnormalitiei are all described and well illustrated. The value of close examination of these often disarming fetuses and associated membranes which may arrive i n the laboratory i n v a r i o u states of disintegration is clearly demonstrated. As in all good pathology, the importance of clinicopathological correlation is emphasircd. This is not an abstruse book. Its subject matter may seem iri-elevant to many pathologists. I t is, however, an extreiiiely useful book which is highly recommended. With the increasing use of prenatal diagnosis and increasing expectations of clinicians and parents, the examinat ion of these specimens will become more frequent and this text will prove to be an invaluable guide to all pathologists.
A Furnsworrh
Boyd's Texlbook of Parhology, 9th Edition, Vol. I . Edited by A . C . Ritchie. Lea and Febiger, Philadelphia, L.ondon, 1990. ISBN 0-8121-0726-8, pp. xxii + 1043 + Ixvii. $87.00. This is a substantial 2 volume work of 2,065 pages (not including the index and prefaces) and is the descendent of Professor William Boyd's Texrbook of Pathology, the first edition of which was published i n 1931 and the eighth in 1970. This is listed as the ninth edition. I t ha\ been updated and in large part rewritten by Professor A.C. Ritchie, a New Zealander and a Fellow of our College, and who occupied the Chair of Pathology at the University of Toronto after Dr. Boyd. There is the unusual accolade of a Publisher's Foreword by MI- R. Kenneth Bussy for the publishers Lea and Febiger which give5 a brief history of the now legendary Dr William Boyd. I t is said that the Mayo brothers helped with a recommendation to a publisher after a fithing expedition with Dr Boyd. Dr Boyd (1885-1979) had a long and eventful life and wa5 one of a distinguished group of academics at the University of Manitoba, Winnipeg for many years. He followed the anatomist John Boileau Grant (also the author of a standard text) to the University of Toronto. Dr Ritchie has maintained the easy readability of Boyd's original text while bringing the advances of the last 20 years into the text. for example, the sections on genetics of cancer, a clear statement on oncogenes and human disease, the section on AIDS etc. In the preface Dr Ritchie details his aims for the text. He states that it "describes the course, development and lesions of the diseases that afflict us, their effect on the patient, the functional and secondary changes they cause, their course and complication\ and the kind of treatment appropriate to overcome them." The 2 volumes are divided into 62 chapters. Firstly, there is a section on general pathology - those changes which underlie many types of disease, in chapters I to 14. In chapters 15 to 21 the infections are considered, probably in more detail than in many other textbook5 of pathology. Chapters 22, 23 and 24 discuss nutritional diseases, physical injury and poisoning respectively. Chapters 25 t o 62 are concerned with the pathology of the barious systems of the body. Illustrations, both photograph5 and diagrams appear not to be as copious as sometimes found iri pathology texts, for example, 1 think that the section on malaria would be improved by a diagram or illustration of the malarial parasites. There is a useful and recent bibliography at the end o f each chapter. The structure of the text and the comprehensibe index allow\ location of the desired section an easy task. This extensive update of Boyd's original work maintains a tradition of lucidity and thoroughness which will recommend the text to another generation of students and pathology registrars.
B. A . Wurren
Pathology Reviews - 1989. Edited by E d ~ w \ u u t . t K L I ~ I ~Iuru . DAhll \NO\ Hurnaria Prci\. Clifton. New Icrsey. Marketed/distributed: John Wile? & Sons, Chiche\ter, N'.Su\\e\. Llh. ISBN: 0-89603-162-4, 1989, p p b i i + 299. 163.20. This book con\istt o f a collection 01 selected w i e u s on topic\ that the editors claim are exploring the interface between biologq and diwase. Both editors head combined departments of Pathology and Cell Biolog? and because of such a background their stated aim has been largely achieved. The various review i n this boluine habe been written b? c\pcrt\ i n particular fieldc. Generally. what they have produced arc' clear. conci\c and up-to-date reports in \\ hich icveral relevant references ha\ e been incorporated for those readers who wish to pursue specilic aspects of the topic. The subject matter focuses on aspects of basic pathology and tor convenience the book ha\ been di\ided into four rections: ( i ) c.ellulai and metabolic disorders; ( i i ) inflanimation and immunity; ( i i i ) tumor biology and ( i b ) methodology. In tlie first section, the highlighl\ ~nclurle amyloidosis, endocytosis and bone remodelling while i n the \econd section aspects of the actions of endotoxin, interleukin-I, tumor iiecro\i\ factor and T-helper lymphocytes are con\idered. as well a \ Ieucoc\ tc actibation, atherosclerosis and mechanism\ of glomerular i i i i i i r ) Chapters on the role of extracellular proteases in cell proliteralion and differentiation, as well as nutritional influences on caicinogene\i\. characterize the third section, ahile the place of flom cyioiiictry i n diagnostic pathology and the use i>ttransgenic mice in parhobioloyy form the subject inattei of the tourth \ecrioii. This is an excellent hooh for pathologist\ and trainee patholo@i\l\ who wish to obtain an intight inlo model-n concept\ 0 1 pathohioloy> as well as for thole experimentali\t\ who wi\h to he intornled 011 topic.\ that are closely related to their field of interest. J hl
P"pclilllr,rll,ol,
The Mepulohlasfic Anaemias, 3rd Edition. 1. C ' H \ \ \ K I ~ . Bl ach~el l Scientific Publications. Oxford. London. Fdinbuish Hosloii. Melbourne, 1990. ISBN 0-632-02549-2, p p . b i i c209. US$114 00. Professor Chanarin has an unparalleled reputation i n the field of tlie megaloblastic anemias, and this hook brings together and coridenw\ h i \ wide experience in a way \bhich is acccsiible to the general reader. For a third edition. i t comez as iomething of a surprise 1 0 find the book smaller than its predecessor\. hut the core material i \ \ti11 more than adequate to provide a comprehensive view of the i u b j e c t One of the casualties in the process o l condensation has heen the i e f c i e n c c \ . which have been C U I from 4258 in [lie second edition to 437 i i i ihc thiid. This is commendable most book\ are over-referenced any\\,r> - but it is disappointing that some of the key bits of inforination ( \ u c h a\, for example, the chromosome location of the I t gene) are not referenced while others mhich are referenced are o f no great consequence. The book ic written in a delightful, personal style mhich i \ ca5y to read. At times the lack of order can be exa\perating, as i n t h e l i \ t of causes of macrocytosis, but this i \ a minor criticism. H a b i n p a final chapter entitled "Odds and Encli" I\, f o r a text book. an original touch. The figures arc excellent and the production s h o w s the profe\\ionalism of the publishers. I t is a pity that for a monograph on rnegaloblastic anemias it was not possible to include I coloured plate \ho\vins a megaloblast. For a book o f this calibre. this would not have beeii an extravagance. ~
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Pa/hi)logy oJ AIDS Test Book and Arlus of Disecisec A s \ i ) c , i u i d Ct'i/h Acquired lniniune De/rcirnc:v S~.rrclronie. H \ K K \ L . 1011 i i i \ t I R Lippincott Company, Philadelphia, Neb\ Yo1 h . London. I S B N 0-397-44556-3. The book Purholog! of AIDS by Harry L loachim is ;I Iaige lorinat and comparatively imall bolunic book of 240 pages 11 I \ ;iciuall> 2