Peculiar facies and eczema

486

Smith

The Journal o[ Pediatrics March 1967

21. PECULIAR FACIES AND ECZEMA (Dubowitz syndrome)

9

9 months; weight 9s/4 pounds Height age at 13 months: 5 months

3 months Height age: 1 month

Same patient at 20 months Height age: 15 months Bone age: 20 months

Small stature. Prenatal onset Facies. Hypoplasia of supraorbital ridges, zygoma, malar eminence, and mandible; short palpebral fissures simulating hypertelorism; prominent auricles Skin. Eczematoid skin eruption; thick skin; sparse hair Etiology. Unknown. A presumably affected sibling of the patient of Dubowitz died at 3 months of age Comment. The unusual facies and eczema suggest that this is a different entity than Bloom's syndrome. The eczema begins early in infancy9 Insufficient numbers of patients have been described to allow for adequate characterization of this condition and its natural course. Dull mentality is suspected REFERENCE

Dubowitz, V.: Familial low birth weight dwarfism with an unusual facies and skin eruption, J. M. Genet. 2: 12, 1965.