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Peer review report 1 on “Effect of perioperative intravenous lidocaine infusion on postoperative recovery following laparoscopic cholecystectomy-A randomized controlled trial”
International Journal of Surgery 37 Supplement 1 (2017) S444
Contents lists available at ScienceDirect
International Journal of Surgery journal homepage: www.journal-surgery.net
Peer Review Report
Peer review report 1 on “Effect of perioperative intravenous lidocaine infusion on postoperative recovery following laparoscopic cholecystectomy-A randomized controlled trial” 1. Original submission 1.1. Recommendation Minor Revision.
inflammatory markers which might be associated with pain. The observation of time to first flatus and bowel movement are notoriously unreliable but have been used by others in this area. Perhaps with some comments on these points, I recommend acceptance of the paper.
1.2. Comments to the author
2. First revision
This is an interesting and well written paper. The idea of using intravenous lignocaine to supplement general anesthesia is not original and the method was used in the 70's for breast surgery. It is beginning to receive a resurgence of interest. A recent Cochrane review concluded that the evidence in favour was low to moderate [Kranke P. et al. Cochrane Anaesthesia, Critical and Emergency Care Group 16 July 2015]. This concluded that there was a suggestion of benefit for those patient with lower abdominal and laparosopic surgery in the first 4 h. This review should be referenced. The discussion of the use of IL6 and IL8 markers is interesting. Upregulation of the genes for these cytokines during the inflammatory process was described by Wang X-M. Pain [2009] 142 (3): 275e83 and also by Scheller J et al. Biochimica Biophysica Acta [2011]. 1813, 5. 878e888. This area is still controversial in that there is no objective measure of pain, rather than just a possible correlation with
2.1. Recommendation
DOI of published article: http://dx.doi.org/10.1016/j.ijsu.2017.07.042. http://dx.doi.org/10.1016/j.ijsu.2017.07.067 1743-9191
Accept. 2.2. Comments to the author Accept with this revision. Michael Jennings Boscoe Independent Practice, Department of Anaesthetics, Brambles, Bakes Wood, Denham, Middlesex UB94LQ, United Kingdom E-mail addresses: [email protected], [email protected].
Contents lists available at ScienceDirect
International Journal of Surgery journal homepage: www.journal-surgery.net
Peer Review Report
Peer review report 1 on “Effect of perioperative intravenous lidocaine infusion on postoperative recovery following laparoscopic cholecystectomy-A randomized controlled trial” 1. Original submission 1.1. Recommendation Minor Revision.
inflammatory markers which might be associated with pain. The observation of time to first flatus and bowel movement are notoriously unreliable but have been used by others in this area. Perhaps with some comments on these points, I recommend acceptance of the paper.
1.2. Comments to the author
2. First revision
This is an interesting and well written paper. The idea of using intravenous lignocaine to supplement general anesthesia is not original and the method was used in the 70's for breast surgery. It is beginning to receive a resurgence of interest. A recent Cochrane review concluded that the evidence in favour was low to moderate [Kranke P. et al. Cochrane Anaesthesia, Critical and Emergency Care Group 16 July 2015]. This concluded that there was a suggestion of benefit for those patient with lower abdominal and laparosopic surgery in the first 4 h. This review should be referenced. The discussion of the use of IL6 and IL8 markers is interesting. Upregulation of the genes for these cytokines during the inflammatory process was described by Wang X-M. Pain [2009] 142 (3): 275e83 and also by Scheller J et al. Biochimica Biophysica Acta [2011]. 1813, 5. 878e888. This area is still controversial in that there is no objective measure of pain, rather than just a possible correlation with
2.1. Recommendation
DOI of published article: http://dx.doi.org/10.1016/j.ijsu.2017.07.042. http://dx.doi.org/10.1016/j.ijsu.2017.07.067 1743-9191
Accept. 2.2. Comments to the author Accept with this revision. Michael Jennings Boscoe Independent Practice, Department of Anaesthetics, Brambles, Bakes Wood, Denham, Middlesex UB94LQ, United Kingdom E-mail addresses: [email protected], [email protected].