Penile Cancer Staging System

Curr Probl Cancer 39 (2015) 146

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Curr Probl Cancer journal homepage: www.elsevier.com/locate/cpcancer

Penile Cancer Staging System Primary tumor (T) TX Primary tumor cannot be assessed T0 No evidence of primary tumor Tis Carcinoma-in-situ Ta Noninvasive verrucous carcinoma T1a Tumor invades subepithelial connective tissue without lymphovascular invasion and is not poorly differentiated (ie, grade 3-4) T1b Tumor invades subepithelial connective tissue with lymphovascular invasion or is poorly differentiated T2 Tumor invades corpus spongiosum or cavernosum T3 Tumor invades urethra T4 Tumor invades other adjacent structures Lymph nodes (N): Pathologic stage (pN) corresponds to clinical stage but based on biopsy or surgical incision NX Regional nodes cannot be assessed N0 No palpable or visibly enlarged inguinal lymph nodes N1 Palpable mobile unilateral inguinal lymph node N2 Palpable mobile multiple or bilateral inguinal lymph nodes N3 Palpable fixed inguinal nodal mass or pelvic lymphadenopathy unilateral or bilateral M1: Distant metastasis Stage Grouping 0 Ta I T1a II T1b T2 T3 IIIa T1-3 IIIb T1-3 IV T4 Any T Any T

N0 N0 N0 N0 N0 N0 N1 N2 Any N N3

M0 M0 M0 M0 M0 M0 M0 M0 M0 M0

International Union against Cancer (UICC) TNM classification of penile cancer.1

Reference 1. Sobin LH, Gospodarowicz MK, Wittekind C, editors. International Union Against Cancer. TNM Classification of Malignant Tumours. 7th ed. Chichester, West Sussex, UK; Hoboken, NJ: Wiley-Blackwell; 2009.

http://dx.doi.org/10.1016/j.currproblcancer.2015.03.011