ORAL AND MAXILLOFACIAL PATHOLOGY e102 Abstracts health professionals to this condition as a possible differential diagnosis and possibly enabling and optimizing aspects involved in the diagnosis and treatment of these patients.
CPP243 - SURGICAL TREATMENT OF ORAL LYMPHANGIOMA IN CHILDREN. PRISCILA LAIZA RUBIM LEÃO, LEANDRO JUNQUEIRA OLIVEIRA, SHEYLA VIANA OMONTE, EDSON COSTA E. SILVA, HELVÉCIO MARANGON JÚNIOR, MARTINHO CAMPOLINA REBELLO HORTA, PAULO EDUARDO ALENCAR DE SOUZA. A 9-year-old male patient presented a soft well-defined mass in the left border of the tongue, dark red colored, measuring 2.0 x 1.5 cm, with 2 years of evolution. The lesion showed translucent superficial vesicles, creating the appearance of frog eggs. Repeated trauma in the region and aesthetic complaints were reported. The differential diagnoses included lymphangioma and lymphohemangioma. An incisional biopsy was performed and the histopathologic examination showed oral mucosa with numerous subepithelial dilated lymphatic vessels filled with homogeneous eosinophilic material. The diagnosis of lymphangioma was established and the lesion was completely removed surgically with satisfactory healing. After 11 months follow-up, a 1.0 x 0.5 cm nodule with superficial vesicles appeared at the same location. The hypothesis of lymphangioma recurrence was proposed and excisional biopsy was performed. The diagnosis was confirmed by histopathology and the patient is under follow-up, without signs of recurrence after 4 months.
CCP244 - DISREGARD OF CASES: DELAYS IN DIAGNOSIS OF ORAL SQUAMOUS CELL CARCINOMA. CATARINA RODRIGUES ROSA DE OLIVEIRA, CAMILA MARIA BEDER RIBEIRO, THAYNÁ MELO DE LIMA, HELISSA MAYANE NUNES DA SILVA OLIVEIRA, ANNA CAROLINA OMENA VASCONCELLOS LE CAMPION, VANESSA DE CARLA BATISTA DOS SANTOS, SONIA MARIA SOARES FERREIRA. Oral squamous cell carcinoma (OSCC) is presented as the most common malignancy in the oral cavity. Its etiology is multifactorial. There are several causes of delay in the diagnosis of OSCC, such as patient and professional’s misinformation, as well as the difficulty to access treatment. The objective of this study is to report 2 cases of delays in OSCC with facial extension, causing destruction and leading to patients’ morbidity as a reflection of disregard and lack of focused public policies for prevention, diagnosis and treatment of this pathology. First case is a female patient, 66 years old, diagnosed in 2016 and the second is a male patient, 85 years old, diagnosed in 2008. As a result of these facts, nowadays there are cases like these in which the destruction of facial tissues remains impressive. These cases emphasize the need of attention to OSCC, head and neck cancer. This serves as a warning to health professionals and managers for the negligence of these patients.
CPP245 - ORAL INVOLVEMENT OF HYPERIMMUNOGLOBULIN E SYNDROME. EDUARDO EUDES NÓBREGA DE ARAÚJO, THAYANARA DA SILVA MELO, GUILHERME SOARES, MARINA LINS MAYMONE DE MELO, ALESSANDRA TAVARES CARVALHO, JAIR CARNEIRO LEÃO, LUIZ ALCINO MONTEIRO GUEIROS.
OOOO August 2017 Hyperimmunoglobulin E Syndrome (HIES) is a primary immunodeficiency characterized by recurrent skin and respiratory tract infections, associated with elevated serum levels of immunoglobulin E. An 8-year-old male patient was referred with multiple ulcerated lesions on the lips, tongue, mouth floor, palate and gums, with a clinical diagnosis of autosomal dominant HIES. Medical history included elevated serum IgE, eosinophilia, recurrent cutaneous abscess, bone fractures and unresponsive mucocutaneous candidiasis. Oral lesions included white plaques intermingled with erythematous lesions in a widespread distribution in the oral mucosa, diagnosed as mucocutaneous candidiasis. Delayed teeth eruption was also observed. An adequate clinical response was achieved with fluconazole 50 mg daily for 15 days, followed by preventive maintenance (fluconazole 50 mg twice/week). After 45 days, he presented with insidious pulmonary tuberculosis followed by sepsis. The patient failed to respond to treatment and died a few days later.
CPP246 - NASOPALATINE DUCT CYST TREATMENT: REPORT OF TWO CASES. PRISCILA LAIZA RUBIM LEÃO, LEANDRO JUNQUEIRA OLIVEIRA, SHEYLA VIANA OMONTE, EDSON COSTA E. SILVA, JESSYCA MICHELLE ALMEIDA, MARTINHO CAMPOLINA REBELLO HORTA, PAULO EDUARDO ALENCAR DE SOUZA. A 62-year-old male patient showed a purplish swelling in the anterior hard palate midline, measuring 1.5 cm, with pain and 40 days of evolution. CT showed a hypodense unilocular area in the incisive foramen region. A 25-year-old male patient presented a swelling in the central hard palate, with pain and 3 weeks of evolution. Radiography showed a unilocular radiolucent area with 2 cm in the anterior maxilla. In both cases, the related teeth responded to the vitality tests, the diagnosis hypothesis of nasopalatine duct cyst was proposed and needle aspiration reveals a translucent liquid. The treatment of both was surgical excision with full palatal flap and curettage. Histopathologic examination showed, in both cases, cystic capsule of fibrous connective tissue, with neurovascular bundle, lined by stratified squamous and cuboidal epithelium, establishing the diagnosis of nasopalatine duct cyst. Both patients were followed-up for 18 months with no signs of recurrence.
CPP247 - PERIPHERAL OSSIFYING FIBROMA IN MAXILLA: CASE REPORT. MARCÍLIO PONTES DE SOUZA, ZINALTON GOMES DE ANDRADE, CAMILA TATYANNE SANTOS DE FREITAS, SARA OLIVEIRA SANTOS, FRANCISCO AMADIS BATISTA, JECONIAS CAMARA. Peripheral ossifying fibroma is a non-neoplastic proliferative lesion that affects the gingival mucosa caused by trauma in the region. This condition progresses slowly, producing a swelling in the affected area and it is often asymptomatic. Female patient, 54 years old, revealed difficulty feeding herself and to use her prosthetics. On examination, was noted a small nodule in the molars on the palate area that appeared 1 year ago, measuring 5 cm in diameter, hard consistency aspect, mild discomfort on palpation. After clinical evaluation was performed incisional biopsy and the material was sent for histopathologic analysis. There were 2 irregular fragments of brownish color, measuring the largest 2 cm x 1.3 cm x 1 cm. Histopathologic findings revealed lesions of mesenchymal origin constituted by the proliferation of spindle cells with moderate deposition of hyaline material and the
OOOO Volume 124, Number 2 presence of calcified osteoid material. The lesion was successfully treated and follow-up was conducted for 12 months to check for recurrence. The patient is in good progress.
CPP248 - PREAURICULAR SINUS: CASE REPORT. MARCÍLIO PONTES DE SOUZA, ZINALTON GOMES DE ANDRADE, CAMILA TATYANNE SANTOS DE FREITAS, FRANCISCO AMADIS BATISTA, JECONIAS CAMARA. Congenital preauricular sinus or Auris Coloboma, is considered a benign malformation of the soft tissues in the preauricular region. This pathology is often isolated, but can manifest associated with congenital anomalies, the right ear is usually most affected. Female patient, 15 years old, with defects near the tragus region, complaining of pain. On examination, there was an increase in volume with signs of inflammation near the edge of the helix. Following this assessment, it was made antibiotic therapy and excisional biopsy. The material was sent for histopathologic analysis and microscopically was observed formation of cavity spaces, containing epithelial lining with few layers of cells with exuberant amount of keratin. This cavity is externalized through a fistulous opening and is moderate inflammatory infiltration in some areas. The patient was monitored for 6 months and recurred.
CPP249 - PERIPHERAL GIANT CELL GRANULOMA: CASE REPORT. HANNAH MARCELLE PAULAIN CARVALHO, MARCELO VINICIUS DE OLIVEIRA, JOEL MOTTA JUNIOR, VALBER BARBOSA MARTINS, GUSTAVO CALVACANTI DE ALBUQUERQUE, TIAGO NOVAES PINHEIRO, FLAVIO TENDOLO FAYAD. The objective of this study is to report about a peripheral granuloma focusing on clinical and histologic characteristics. This pathology is a benign lesion, with an uncertain etiopathogenesis, histologically presenting multinucleated giant cells. Female patient, 14 years old, attended the service complaining about maxilla swelling. Clinical examination showed a pedunculated and ulcerated lesion, with hyperemia, resilient consistency, painless and bleeding on touch, located in the gingival margin of teeth 25, 26 and 27. On the image exam, it was noticed radicular rest of tooth 26. The chosen conduct was excisional biopsy in hospital, realizing the closing with Bichat’s ball and subsequent submission to the laboratory. During surgery, the lesion was firm, with inaccurate limits and a hyperemic color similar to gingival tissue inflammation. Patient is under observation for 7 weeks without recurrences.
CPP250 - CARCINOMA EX PLEOMORPHIC ADENOMA OF A MINOR SALIVARY GLAND: A CASE REPORT. JORDANNY SANTOS OLIVEIRA, CAMILA TATYANNE SANTOS DE FREITAS, SARAH OLIVEIRA DOS SANTOS, PAULO VITOR MOURÃO MACHADO, JECONIA CÂMARA, NAÍZA MEDEIROS MENEZES ABRAHIM. Carcinoma ex pleomorphic adenoma is a rare and aggressive malignancy that usually develops in primary or recurrent pleomorphic adenoma. A 55-year-old male patient presented a swelling on the palate with 2 years history of evolution, reporting difficulty in adaptation of upper dentures. Intraoral examination revealed a mass covered with non-ulcerated mucosa of firm
ABSTRACTS Abstracts e103 consistency, non-tender. The lesion was completed excised and sent to microscopic evaluation. Histopathologic examination revealed a neoplastic lesion characterized by proliferation of cells, resembling myoepithelial cells, disposed in lumen structure bounded by eosinophilic, cuboidal, intercalated duct-like cells, embedded in a myxoid background stroma. Capsular integrity was incomplete with infiltration by islands of atypical cells with hyperchromatic and hypertrophic nucleus, amid necrosis areas suggesting malignancy. The diagnosis of carcinoma ex pleomorphic adenoma was established. The patient is on follow-up of 1 year and there are no signs of recurrence.
CPP251 - CALCIFYING CYSTIC ODONTOGENIC TUMOR ASSOCIATED WITH ODONTOMA: A CASE REPORT. ZINALTON GOMES DE ANDRADE, CAMILA TATYANNE SANTOS DE FREITAS, MARCILIO PONTES DE SOUZA, NAIZA MENEZES MEDEIROS ABRAHIM, SARAH OLIVEIRA DOS SANTOS, FRANCISCO AMADIS BATISTA FERREIRA, JECONIAS CÂMARA. The calcifying cystic odontogenic tumor is a rare developmental lesion that arises from the odontogenic epithelium. An 8-year-old female patient, featuring swelling involving mandible body region. Radiographic examination revealed presence of radiolucent image, circumscribed and involving teeth without root resorption. The histopathologic analysis showed large cystic cavities lined by thin epithelium that was thickened in other areas, with cells featuring increased eosinophilia with ghost cells characteristics and points with dystrophic calcifications. It was observed cords and nests of columnar epithelial cells that are arranged parallel on the periphery. It is noted still that dental germ formation consists of stellate cells layers to enamel organ, odontoblasts layer with dental matrix production and areas with fusiform cells which suggest dental papilla. Based on clinical, radiographic and histologic, the diagnosis of Calcifying Cystic Odontogenic Tumor associated to Odontoma was confirmed. The patient is under observation and after 1 year of follow-up, there is no evidence of recurrence.
CPP252 FOLLICULAR AMELOBLASTOMA: A CASE REPORT. ZINALTON GOMES DE ANDRADE, CAMILA TATYANNE SANTOS DE FREITAS, MARCILIO PONTES DE SOUZA, MOYARA MENDONÇA LIMA DE FARIAS, HANNAH MARCELLE PAULAIN CARVALHO, JOEL MOTTA JUNIOR, JECONIAS CÂMARA. Odontogenic ameloblastoma of the jaw is a rare neoplasia of the oral cavity. A 42-year-old female patient, with a chief complaint of swelling in the left side of the posterior mandible. On palpation, the lesion was firm and fixed. A radiologic examination showed multilocular radiolucencies involving molars without root resorption. The resected specimen was sent for histopathologic examination. The histopathologic analysis showed neoplastic lesion of odontogenic origin, featuring epithelial islands bordered by tall and hyperchromatic cells that resemble ameloblasts. In the central area, it was observed a loose arrangement of these cells resembling reticulum stellate enamel organ; in some of these structures, it is observed keratin formation characteristic aspect of acanthomatous and in some of these islands, the cells of the enamel organ degenerates displaying a cystic aspect. Based on clinical, radiographic and histologic, the