Physciological pharmaceutics: Biological barriers to drug absorption

Physciological pharmaceutics: Biological barriers to drug absorption

particle size distribution. Chapter II deals with the effect of the interaction of absorbent polymer and pulp on the performance of diapers. Chapter 1...

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particle size distribution. Chapter II deals with the effect of the interaction of absorbent polymer and pulp on the performance of diapers. Chapter 13. the last chamer of the book, describes the microstructural analysis ofagraft copolymer. HMHEC (hydrophobically modified hydroxyethyl cellulose). These chapters provide diversitied eaperimental results on absorbent polymers ranging from novel polyelectrolyte gels 10 mdustrial absorbents. Although this book covers both the theoretical and experimental aspects ofabsorbent polymers with a detinitivc llavour towards industrial RP-

interested in wellable or swelling-controlled delivery systems. This book is also useful for polymer scientists and researchers interested in the pbysicocbemicsl aspects of neutral and polyelectrolyte gels, polymer complexation, and transport in porous polymers. Overall, this is an excellent reference volume for those who are interested in hydrophillic network polymers. The editors should be commended for their effort in putting together an exceptional volume with admirably uniform print style and clarity of figures, which was produced from camera-ready originals.

plications in prrsonol cnrc products. the same fundamental polymer btructura.I considerations should be cxtremcly valuable for scientists and researchers in the controlled release tie’d who arc

The book reviewed herr is a most enjoyable monograph which should be on the bookshelves ofall controlled release researchers who are trying to devise new deliveq systems for a wide range of routes of administration. The book defines the adsorption sites and mechanisms, as well as biological barriers for the oral. gastroiNestmal. transdermal. ocular, nasnl and pulmonary administration. The clarity and style of presentation are outstanding. Anatomi-

cal and physiological characteristics for each administration route are followed by a clear presentation describing cellular and other barriers. In the process, the authors analyze problems with drug absorption and point out related literature. As scintigrapby is the favorite experimental technique of these investigators, such iavestigations are offered as proof of adsorption. Overall, this is an excellent, concise book with a detailed (but not exhaustive) bibliographic search. Highly recommended.