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Pleomorphic Adenoma in the Parotid Gland
PATH TO PATIENT IMAGE QUIZ
Pleomorphic Adenoma in the Parotid Gland Lori A. Erickson, MD
A
superficial parotidectomy revealed a well-circumscribed, fleshy, bulging mass. Pathologic examination identified a pleomorphic adenoma.
From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Which statement is most accurate about these tumors?
a. Pleomorphic adenoma is the most common salivary gland neoplasm b. The vast majority of these tumors occur in the sublingual gland
c. Pleomorphic adenoma most commonly occurs in children and rarely occurs in adults d. Pleomorphic adenomas almost always arise in the deep lobe of the parotid gland
(see page e56 for answer) Mayo Clin Proc. n March 2017;92(3):e55-e56 n http://dx.doi.org/10.1016/j.mayocp.2017.01.006 www.mayoclinicproceedings.org n ª 2016 Mayo Foundation for Medical Education and Research
e55
MAYO CLINIC PROCEEDINGS
Answer: a. Pleomorphic adenoma is the most common salivary gland neoplasm
Pleomorphic adenomas account for the majority of salivary neoplasms and most commonly occur in the superficial lobe of the parotid gland. They can involve the submandibular and minor salivary glands but rarely involve sublingual glands. These tumors most commonly present in the fourth to fifth decade of life but can occur over a wide age range. They are benign tumors but can recur, often in a multifocal pattern, and be difficult to treat.1 These tumors may also be associated with malignant transformation. Microscopy shows an encapsulated tumor with epithelial and myoepithelial components as well as mesenchymal and stromal components.
REFERENCE 1. Abu-Ghanem Y, Mizrachi A, Papovtzer A, Abu-Ghanem N, Feinmesser R. Recurrent pleomorphic adenoma of the parotid
e56
Mayo Clin Proc.
n
gland: institutional experience and review of the literature. J Surg Oncol. 2016;114(6):714-718.
March 2017;92(3):e55-e56
n
http://dx.doi.org/10.1016/j.mayocp.2017.01.006 www.mayoclinicproceedings.org
Pleomorphic Adenoma in the Parotid Gland Lori A. Erickson, MD
A
superficial parotidectomy revealed a well-circumscribed, fleshy, bulging mass. Pathologic examination identified a pleomorphic adenoma.
From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Which statement is most accurate about these tumors?
a. Pleomorphic adenoma is the most common salivary gland neoplasm b. The vast majority of these tumors occur in the sublingual gland
c. Pleomorphic adenoma most commonly occurs in children and rarely occurs in adults d. Pleomorphic adenomas almost always arise in the deep lobe of the parotid gland
(see page e56 for answer) Mayo Clin Proc. n March 2017;92(3):e55-e56 n http://dx.doi.org/10.1016/j.mayocp.2017.01.006 www.mayoclinicproceedings.org n ª 2016 Mayo Foundation for Medical Education and Research
e55
MAYO CLINIC PROCEEDINGS
Answer: a. Pleomorphic adenoma is the most common salivary gland neoplasm
Pleomorphic adenomas account for the majority of salivary neoplasms and most commonly occur in the superficial lobe of the parotid gland. They can involve the submandibular and minor salivary glands but rarely involve sublingual glands. These tumors most commonly present in the fourth to fifth decade of life but can occur over a wide age range. They are benign tumors but can recur, often in a multifocal pattern, and be difficult to treat.1 These tumors may also be associated with malignant transformation. Microscopy shows an encapsulated tumor with epithelial and myoepithelial components as well as mesenchymal and stromal components.
REFERENCE 1. Abu-Ghanem Y, Mizrachi A, Papovtzer A, Abu-Ghanem N, Feinmesser R. Recurrent pleomorphic adenoma of the parotid
e56
Mayo Clin Proc.
n
gland: institutional experience and review of the literature. J Surg Oncol. 2016;114(6):714-718.
March 2017;92(3):e55-e56
n
http://dx.doi.org/10.1016/j.mayocp.2017.01.006 www.mayoclinicproceedings.org