Point-Counter-Point: Psychotherapy in the Age of Pharmacology

Point-Counter-Point: Psychotherapy in the Age of Pharmacology

P o i n t - C o u n t e r- P o i n t : Psychotherapy in the Age of Pharmacology Helen D. Pratt, PhD a,b, * KEYWORDS  Psychotherapy  Pharmacother...

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P o i n t - C o u n t e r- P o i n t : Psychotherapy in the Age of Pharmacology Helen D. Pratt,

PhD

a,b,

*

KEYWORDS  Psychotherapy  Pharmacotherapy  Evidenced-based and empirically supported treatments  Children and adolescents

The long-held view that medicine or therapy is an “art” is quickly becoming obsolete. To procure referrals and reimbursement, clinicians are being forced to be accountable (ie, use empirically supported, effective, reproducible, and efficient treatment interventions) by insurance companies, professional credentialing bodies, and their consumers.1–5 This article focuses on reviews of treatment interventions by scholars, researchers, clinicians, and study groups who have examined multiple databases of published studies, and ongoing treatment protocols. Evidence-based and empirically supported treatments (ESTs) for children and adolescents for treatment of mental and behavioral disorders are reviewed. A LITERATURE REVIEW

Significant controversy continues to exist in the medical and psychological fields surrounding which therapies become designated as evidence based or empiric. Problems in methodology, subject selection, and measures plague most published studies.6 Review articles were drawn from 9 major search engines: 4 where peerreviewed articles on psychopharmacology versus psychotherapy with children and adolescents were the search criteria (First Search, Psych abstracts, Medline, EBSCOhost) and 5 research databases where reviewers had specified specific inclusion criteria, the topic, exclusion criteria, and identified treatment interventions. These databases included (1) National Registry of Evidence-based Programs and Practices (NREPP),7 (2) The Office of Behavioral and Social Sciences Research (OBSSR),8

a

Department of Pediatrics and Human Development, Michigan State University, College of Human Medicine, East Lansing, MI 48824-1317, USA b Behavioral and Developmental Pediatrics, Pediatrics Program, Michigan State University/ Kalamazoo Center for Medical Studies, 1000 Oakland Drive, Kalamazoo, MI 49008, USA * Department of Pediatrics and Human Development, Michigan State University, College of Human Medicine, East Lansing, MI 48824-1317. E-mail address: [email protected] Pediatr Clin N Am 58 (2011) 1–9 doi:10.1016/j.pcl.2010.10.012 pediatric.theclinics.com 0031-3955/11/$ – see front matter Ó 2011 Elsevier Inc. All rights reserved.

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(3) Evidence-based Mental Health Treatment for Children and Adolescents,8 (4) National Association of Cognitive-Behavioral Therapists (NACBT),9 and (5) Cochrane Database of Systematic Reviews.6 Four of the 5 databases defined and described criteria for selection of articles and reviews from primarily behavioral and cognitive behavioral resources and were procured from a wide variety of search engines (Box 1).6–10 Criteria for Cochrane Database of Systematic Reviews matched the 4 others but included articles and reviews from a variety of disciplines (eg, psychology, psychiatry, nursing, ambulatory medicine). Keywords used were psychopharmacology versus psychotherapy, mental health 1 psychotherapy, and psychotherapy 1 treatment interventions for children

Box 1 Major databases used for this review Applied Social Sciences Index and Abstracts (ASSIA) British Nursing Index (1994 to 2006) Campbell Library (including SPECTR and CENTRAL) Computer Retrieval of Information on Scientific Projects (CRISP) Cumulative Index to Nursing and Allied Health Literature (CINAHL) Cochrane Depression, Anxiety and Neurosis Trial Register Cochrane Central Register of Controlled Trials Cochrane Depression, Anxiety and Neurosis Group Register Dissertation-Abstracts International EBSCOhost Education Resources Information Center (ERIC) EMBASE is a biomedical database OCLC First Search Latin American and Caribbean Health Sciences Literature (LILACS) MEDLINE MetaRegister of Controlled Trials Ongoing and unpublished trials National Research Register (NRR) Pharmaceutical companies Ongoing and unpublished trials PsycINFO RCN database System for Information on Gray Literature in Europe Archive (SIGLE) Study Reference Lists Sociofile Sociologic Abstracts Sociologic Abstracts Sportdiscus part of Sports Research Intelligence Supportive Web of Science World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) Note: most of these databases are fee for service.

Psychotherapy in the Age of Pharmacology

and adolescents. Only empiric studies were included and details for the methodology are included on specific Web sites. These databases include a range of reviews and a variety of studies from several disciplines. This search yielded 130 reviews; 22 reviews focused on children or adolescents and also reviews of treatment interventions for mental health disorders.11–23 One review looked at pharmacologic versus psychological treatments for specific diseases and concluded that there were no significant differences between the two types of intervention, although both were effective. The Cochrane reviews also supported the findings from reviews conduced as part of the Evidence-Based Mental Health Treatment for Children and Adolescents group,24–41 Evidence-based Therapy site, and the National Registry of Evidence-based Programs and Practices (NREPP) site. PHARMACOTHERAPY

Empiric evidence supports that a combination of pharmacotherapy and psychotherapy is more beneficial to children and adolescents (attention deficit hyperactivity disorder [ADHD], body dysmorphic disorder, depression, oppositional defiant disorder, and substance abuse).1–3,5,16 The Multimodal Treatment Study of Children with Attention Deficit and Hyperactivity Disorder study comparing pharmacology and psychotherapy in the treatment of children diagnosed with ADHD is the exception; however, these results are highly controversial and contested by several research psychologists.2 For discussion of specific drugs effective in the treatment of mental health disorders outside the scope of practice and training of the current author, readers are referred to an excellent text written for clinicians and edited by Greydaus and colleagues42 entitled Pediatric and Adolescent Psychopharmacology: A Practical Manual for Pediatricians. PSYCHOTHERAPY

Psychotherapy can be a very effective tool for management of mental health disorders with children and adolescents, especially for parents and patients who may object to the use of pharmacotherapy. Some parents may not want their children medicated for a number of reasons. Some children and adolescents do not physiologically tolerate medications used to treat mental and behavioral health disorders. Additional obstacles to prescribing medication are the following: (1) some children reach the maximum dosage of a specific medication and can no longer be given higher dosages; (2) some youth are on multiple medications and are at the point where adding more medications or increasing dosages causes serious neurologic, gastrointestinal, or emotional side effects; and (3) many behavioral problems are not resolved with medication when there is an emotional component or environmental cause for the child’s behavioral responses (eg, family conflict). Table 1 contains a list of evidence- and empirically supported treatments.24–41 Cognitive behavior therapy was the most researched form of psychotherapy and provided the most evidence to support its effectiveness in the treatment of depression, anxiety, disruptive behavior problems, posttraumatic stress disorder (PTSD), and substance abuse in adolescents. Patient referrals for psychotherapy may result in the patient being denied access because of several issues that make access to psychotherapy difficult:  Even with current changes in reimbursement rules, many insurance companies do not honor the concept of parity between clinicians who provide mental health and those who provide medical services. Those panels usually do not reimburse for services delivered based on diagnoses of behavioral disorders of childhood

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Table 1 Evidence-based mental health treatment for children and adolescents

Anxiety, general symptoms School refusal behavior Child and adolescent OCD

Well-Established

Probably Efficacious

None None None

I CBT None I CBT individual CBT, plus sertraline (Zoloft) CBT CBT None CBT Behavior therapy CBT

Child and adolescent PTSD Social phobia Specific phobia Children

CBT trauma focused CBT None None

Adolescents

IPT Individual IPT

Child and adolescent ADHD

Behavior therapy

N/A

Oppositional defiant disorder Conduct disorder

Behavior therapy

CBT Behavior therapy Multisystemic therapy

Children

CBT

Adolescents

CBT IPT

CBT Behavior therapy CBT IPT

Disruptive behavior problems

Depression

Adolescent Substance abuse

CBT Group CBT Family therapy

Family therapy Multisystemic therapy

Adolescent anorexia nervosa

Family therapy

N/A

Adolescent bulimia nervosa

N/A

N/A

Child and adolescent BPD

N/A

Family therapy N/A

Early autism

Behavior therapy

N/A

Anorexia nervosa Bulimia nervosa Bipolar disorder

Autism

Psychotherapy in the Age of Pharmacology

Abbreviations: ADHD, attention deficit hyperactivity disorder; BPD, bipolar disorder; CBT, cognitive behavior therapy; IPT, interpersonal psychotherapy; N/A, not applicable; OCD, obsessive compulsive disorder; PTSD, posttraumatic stress disorder. Adapted from the Web site of the Association for Behavioral and Cognitive Therapies and the Society of Clinical Child and Adolescent Psychology Evidencebased Mental Health Treatment for Children and Adolescents. Available at: http://www.abct.org/sccap/?m5sPro&fa5pro_ESToptions#sec2. Updated July 30, 2010. Accessed September 4, 2010. Reprinted from Greydaus DE, Calles Jr JL, Patel DR, editors. Pediatric and adolescent psychopharmacology: a practical manual for pediatricians. Cambridge (NY): Cambridge Medical; 2008. p. 12–4; with permission.

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and cap reimbursement for those mental health services they do provide. If services are covered, the reimbursements are at a lower rate than for medical services. These factors make the cost of mental/behavioral health services more burdensome for parents who are responsible for payment. Clinicians trained or credentialed in the treatment of mental/behavioral disorders with infants, children, and adolescents are not always available to provide care. Even fewer of these experts are trained to specifically treat youth with severe metal and behavioral disorders (ie, schizophrenia, or a combination of mental disorders and developmental disabilities, neurologic disorders, or severe mental disorders). Managed care panels limit the numbers of mental health clinicians they will add to their provider panels, thereby limiting their access to reimbursement from those panels for services provided. Parents and youth who are in psychological distress often want immediate relief but this is not generally possible whether the treatment is pharmacotherapy or psychotherapy. Both are time-consuming processes with medicines often advertised as faster acting. Pharmacotherapy requires supervision and sometimes assertiveness by parents to administer the prescribed medication to their child or adolescent. However, parents may falsely believe that they do not have to change to “fix” their child/adolescent because the “medicine” will “fix” the child’s/adolescent’s problem. Psychotherapy often requires daily and/or weekly involvement by the whole family (especially parents) who must devote time, energy, and effort to implementing treatment intervention; youth must be transported to the treating clinician and the process can be disruptive to the family routine. If a patient receives psychosocial treatment, his or her parents are also expected to change their behaviors to support their child’s treatments gains. Referrals: Physicians must have knowledge of other clinicians and their treatment modalities to select appropriate referral resources. They must also maintain collegial relationships with those clinicians to ensure that their patients are receiving care and benefiting from that care. Although parents, teachers, and some adolescents will demand pharmacologic treatment, primary care physicians should consider the use of psychological and psychosocial treatments as a first line of treatment, or in combination with prescribing medicines.

Psychosocial treatments for emotional, behavioral, and mental disorders can be very effective and sufficient in resolving problems. However, in the case of severe or reoccurring emotional, behavioral, and mental disorders, a combination of pharmacotherapy and psychotherapy increases the positive effects of treatment. SUMMARY

Behavioral and cognitive-behavioral therapies were most often identified as wellestablished treatments for specific mental and behavioral health disorders in children and adolescents. Psychotherapy alone or in conjunction with pharmacotherapy can be a powerful tool in helping youth manage or eliminate negative outcomes of mental and behavioral disorders. Youth should receive a comprehensive medical evaluation before being referred for psychosocial treatment. When referring patients for psychotherapy, it is important to maintain contact with the treating therapist and to remember to tell patients and their parents that the process for accessing treatment, evaluation, and the treatment process are often lengthy.

Psychotherapy in the Age of Pharmacology

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