Poster 087: Biological Differences Between Jaw and Iliac Bone Marrow Stromal Stem Cells

Scientific Poster Session the patients were treated by the same oral and maxillofacial surgeon. The RIF technique was used in all surgical treatments and maxillomandibular fixation was not necessary beyond the intraoperative period. Results: A total of 126 subjects suffered mandible fractures either associated or not with other maxillofacial fractures and a total of 201 mandible fractures were found. The etiology most frequently observed in this retrospective study was traffic accidents. The incidence of mandible fractures was more prevalent in males, in Caucasians, and during the third decade of life. The site most affected was the condyle, followed by the mandibular body. The most common sign was facial swelling, followed by limitation in opening the mouth and malocclusion. Sensorial mental nerve dysfunction was the most common transient complication. Infection was observed in 10 subjects (8.1%), 8 being males and 2 being females. By cross-checking the data collected from infection and etiology, we observed that 4 cases (40%) of violence and 6 cases (60%) of traffic accidents developed infections. Conclusion: This retrospective study of the epidemiology and treatment of mandibular fractures revealed that the therapy applied was effective in handling this kind of fracture and also showed comparable rates of success to published data around the world. References Ellis E, Moos KF, El-Atar A: Ten years of mandibular fractures: an analysis of 2,137 cases. Oral Surg Oral Med Oral Pathol 59:120, 1985 Gabrielli MAC, Gabrielli MFR, Marcantonio E, et al: Fixation of mandibular fractures with 2.0-mm miniplates: review of 191 cases. J Oral Maxillofac Surg 61:430, 2003

POSTER 087 Biological Differences Between Jaw and Iliac Bone Marrow Stromal Stem Cells Hong-Bing Jiang, PhD, Oral and Maxillofacial Surgery Department, Affiliated Stomatological Hospital, Nanjing Medical University, 136 Hanzhong Road, Nanjing, Jiangsu, 210029, China (Tao ZJ; Xu YB; Wang XW) Bone marrow stromal cells (MSCs) can differentiate into bone, cartilage, adipose tissue, and other tissue, but there are few studies on MSCs from jaw bone. It is well known that cranio-maxillofacial bone derives from ectomesenchymal cells which come from cranial neural crest cells. orofacial bone development differs from that of axial and appendicular bone formation. Whether there exist bilological differences between jaw and iliac marrow stromal stem cells is an important title for the studies of jaw bone regeneration. To compare the biological characteristics of bone marrow stromal cells from rat mandible and ilium respectively. MSCs were isolated and proliferated by culture in vitro. The biological characteristics of MSCs derived from mandible and ilium 120

were compared, including growth curve, osteogenic induction and adipogenic differention. Results demonstrate that mandible MSCs proliferate faster and can form more calcium accumulation than iliac cells, while the latter has higher ability of adipogenesis in the adipogenic supplements. Therefore, MSCs from different sites of the same individual have distinct biological characteristics. The obtained results may give insight to the further research of pathological changes and local repair and regeneration of mandible. References Matsubara T. et al. Alveolar Bone Marrow as a Cell Source for Regenerative Medicine: Differences Between Alveolar and Iliac Bone Marrow Stromal Cells. Journal of Bone and Mineral Research, 2005, 20:399 Akintoye SO. et al. Skeletal site-specific characterization of orofacial and iliac crest human bone marrow stromal cells in same individuals. Bone, 2006, 38:758

POSTER 088 Periodontal Healing of Marginal Flap Versus Paramarginal Flap in Palatally Impacted Canine Surgery: A Prospective Study Hu ¨ seyin Ko ¨¸sger, DDS, PhD, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cumhuriyet University, Sivas, 58140, Turkey (Polat HB, Demirer S, ¨ zdemir H, Ay S) O Purpose: The aim of this study was to compare the influence of two mucoperiosteal flaps, marginal and paramarginal, on periodontal healing of adjacent maxillary teeth after extraction of palatally impacted canines. Patients and Methods: Marginal (15 patients) and paramarginal (16 patients) techniques were used to remove palatally impacted canines. The periodontal examination of the adjacent teeth included evaluation of the plaque index (PI), gingival index (GI), probing depth (PD), and clinical crown length (CL) at preoperatively and 1st, 3rd, and 6th months postoperatively by using an individual acrylic stent. Results: No significant differences between the marginal and the paramarginal flaps were found with respect to PI, GI, labial and palatal PD, and labial and palatal CL at all determination times. Paramarginal flap design showed a significant decrease in PI and GI at 6th month. Conclusion: Paramarginal flap design is a good alternative when impacted canine is just under the mucosa. However, there were no significant differences between marginal flap and paramarginal flap in palatally impacted canine surgery related to periodontal healing. References Suarez-Cunqueiro MM, Gutwald R, Reichman J, et al: Marginal flap versus paramarginal flap in impacted third molar surgery: a prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 95:403, 2003

AAOMS • 2008