OOOO Volume 123, Number 2 Extraoral examination revealed no changes. On intraoral examination, a nodular, endophytic, slightly purple lesion of firm consistency was observed in the left maxillary posterior region. Radiographic exam suggested the presence of bone erosion. Computed tomography revealed an infiltrative lesion in the left alveolar ridge, with erosion in maxillary walls and invasion of palatine canal, pterygopalatine fossa and fat pad. Needle aspiration biopsy revealed a serosanguineous liquid. After incisional biopsy, the pathological examination showed an infiltrating neoplasm, with presence of epithelial and myoepithelial cells in tubular and cribriform arrangement, filled with mucoid material and hyaline stroma. Myoepithelial cells were shown by immunohistochemistry (SME+, CK5/6+, 34bE12+). The chosen treatment was radiotherapy. The patient is still being followedup and shows no signs and symptoms.
PP - ASSOCIATION OF CLINICAL, HISTOPATHOLOGICAL AND IMAGINOLOGIC EXAMS FOR DIAGNOSIS OF MANDIBULAR LESIONS. BERNAR MONTEIRO BENITES, MARCELO MARCUCCI, EDUARDO FREGNANI, CLAUDIA PEREZ FRAGA, ANA CLAUDIA LUIZ, LUIZ GUILHERME CERNAGLIA AURELIANO DE LIMA, GUILHERME TRAFANI SANCHES. CEPE - CENTRO DE ESTUDOS E PESQUISA EM ESTOMATOLOGIA/HELIÓPOLIS/ICESP. Association of clinical, histopathological and imaginologic exams for diagnosis of mandibular lesions. The patient, a 27year-old woman, melanoderma, came to the Stomatology service complaining of pain, discomfort and paresthesia in the mandible, which began after left third molar extraction. Patient had medical history neurological treatment for trigeminal neuralgia with Carbamazepine for five months, without significant improvement in clinical symptoms. Intraoral clinical examination revealed slight increase in volume in left mandibular region. The panoramic radiograph performed showed a mixed destructive unicentric lesion, in the posterior region of the left mandible. Computed-tomography revealed an expansive hyperdense lesion with ill-defined borders and periosteal reaction affecting the left mandibular body and angle. Synchronously, a lesion with clinical and imaginologic features compatible with those of simple bone cyst was observed in right mandibular posterior region. The incisional biopsy sent for histopathologic study showed a chondroblastic osteosarcoma, with tumor cells lying in the lacunae, forming lobules. The lobule center showed bony trabeculae with a feathery appearance. After diagnosis, the patient was referred for cancer treatment, underwent radical surgery and is now undergoing radiotherapy. Combined clinical, radiographic and histopathologic analysis before definitive diagnosis is prudent, especially in mandibular osteosarcomas.
PP - GIANT MUCOCELE OF THE MAXILLARY SINUS - AN UNUSUAL FINDING. ADRIELE FERREIRA GOUVÊA, REBECA DE SOUZA AZEVEDO, RAFAELA ELVIRA ROZZA DE MENEZES,
ABSTRACTS Abstracts e49 DANIELLE NOBRE LOPES, KARLA BIANCA FERNANDES DA COSTA FONTES, RENATA TUCCI, ADEMAR TAKAHAMA, JUNIOR. UNIVERSIDADE FEDERAL FLUMINENSE, ESTOMATOLOGIA E PATOLOGIA ORAL - NOVA FRIBURGO, RIO DE JANEIRO, BRAZIL. Giant mucoceles of the paranasal sinuses are uncommon lesions, especially in the maxillary sinuses. They occur as a result of sinusal accumulation and retention of mucous secretions due to persistent or intermittent obstruction of the sinus ostium or obstruction of a mucous-secreting gland, leading to an expansive mass. The pressure caused by this mucous secretion accumulation can destroy the bone walls, with ocular and intracranial involvement. The authors present the case of a giant sinusal mucocele causing bone destruction in a middle-aged patient complaining of facial asymmetry for the last three months. Based on clinical evidence and imaging findings, a number of diagnostic hypothesis were considered, even a sinus carcinoma. The clinicopathologic data and image findings will be discussed as well as the treatment modalities. This case highlights the importance of the histopathological findings leading to the correct final diagnosis.
PP - PREVALENCE OF MALIGNANT ORAL LESIONS IN PATIENTS TREATED IN THE NATIONAL ONCOLOGY CENTRE OF LUANDA, ANGOLA. ADELINO ANTÓNIO ARTUR ABRANTES, FERNANDA VIVIANE MARIANO, FERNANDO MIGUEL, JUSTO LÓPEZ ZAMORA, FILIPE MODOLO, ROGÉRIO OLIVEIRA GONDAK. NATIONAL ONCOLOGY CENTRE, LUANDA, ANGOLA/FEDERAL UNIVERSITY OF SANTA CATARINA, FLORIANÓPOLIS, BRAZIL. The prevalence of malignant oral neoplasms obeys a gender distribution and has been associated with several risk factors such as smoking, alcoholism, poor oral hygiene, air pollution, immunodeficiencies and solar exposure. With the objective of determining the prevalence of malignant oral lesions in patients treated at the National Oncology Centre of Luanda, an observational descriptive retrospective study was done, between 2007 and 2014. All patients answered a standard questionnaire and underwent oral clinical examination. Additional clinical information was found in the medical records and histopathological data of the lesions in the pathological reports. Of the 11,526 patients treated, 843 were diagnosed with malignant oral lesions, of which 554 with Kaposis sarcoma, 80 with nonHodgkins lymphoma, 67 with epidermoid carcinoma, 53 with Hodgkins lymphoma, 45 with osteosarcoma and 44 with basal cell carcinoma. The average age of the diagnosed patients was 32.1519.58 years, of those, 66.3% were male and 33.7% female. Regarding the clinical staging, 4.67% of the patients were classified as Stage I, 24% Stage II, 53% Stage III, and 18.33% Stage IV. Thus, it is concluded that early detection of precancerous lesions associated with preventive policies could contribute to the reduction of mortality caused by malignant neoplasms.