- Email: [email protected]
PP - PRIMARY LOCALIZED AMYLOIDOSIS ON TONGUE
OOOO Volume 123, Number 2 PP - THE BENEFIT OF INTRAORAL STENT DURING HEAD AND NECK RADIOTHERAPY: A PROSPECTIVE STUDY. JULIANA ROCHA VERRONE, GRAZIELLA CHAGAS JAGUAR, ANTÔNIO CÁSSIO ASSIS PELLIZZON, PETRUS PAULO COMBAS EUFRAZIO DA SILVA, ALESSANDRA DAS DORES MARCICANO, JOSÉ DIVALDO PRADO, FÁBIO DE ABREU ALVES. A.C. CAMARGO CANCER CENTER, SÃO PAULO-SP, BRAZIL. The intraoral stent is a mouth-opening device which may be used during head and neck cancer radiotherapy (RT) with the intention of preventing unnecessary irradiation in normal adjacent tissue. No prospective studies have shown the benefit of stent RT. Objective: To evaluate the dosimetry analysis in oral and oropharyngeal cancer patients during RT and verify its impact on the RT technique (three-dimensional radiotherapy - 3DRT versus intensity-modulated radiotherapy -IMRT). Methods: 53 patients (16 of 3DRT and 37 of IMRT) were prospectively submitted to pre-irradiation planning computed tomography (with and without the use of stent). Results: A significant lower radiation dose was observed in healthy structures contralateral to the tumor using the stent compared with its nonuse for both oral and oropharyngeal cancer. Interestingly, patients who wore the stent and underwent IMRT planning showed significantly better results in decreasing radiation dose in healthy structure compared with patients without stent, or who underwent 3DRT. Conclusion: The use of stent allowed for decreased radiation dose in healthy structures during RT for oral and oropharyngeal cancer, and the combination of this device and IMRT seems to produce greater improvement in the patientsquality of life. This study was sponsored by FAPESP and CNPq.
PP - PRIMARY LOCALIZED AMYLOIDOSIS ON TONGUE. VICTOR YURI NICOLAU FERREIRA, TÁCIO CANDEIA LYRA, LAUDENICE DE LUCENA PEREIRA, DANYEL ELIAS DA CRUZ PEREZ, PANMELLA PEREIRA MACIEL, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Amyloidosis is a rare disease caused by pathologic deposition of folded proteins on extracellular matrix and can be primary or secondary. This work aims to report case of primary localized amyloidosis on tongue affecting a female with 79 years-old. This patient was referred to our reference center complaining of dysphagia and painful mass on her tongue. She referred intense weight-loss during a couple of months. No alterations were observed on oral examination and the intraoral examination revealed generalized macroglossia and multiple unitary resistant nodules with yellowish surface on dorsal, lateral and ventral surfaces were clear. We considered amyloidosis as primary diagnostic hypothesis and an incisional biopsy was taken. We evaluated the feasible association with a systemic process and ordered some exams such as CBC, echocardiogram, renal ultrasound, gastrointestinal tomography, colonoscopy, radiographs of the whole body, and Bence Jones protein mensuration. All exams revealed normality and absence of signs of systemic disease. The microscopic examination revealed a proteinaceous material under positive epithelial tissue to Red Congo showing birefringence. This case was diagnosed as primary localized amyloidosis on tongue and the patient was referred to hematologist for treatment. She is currently under systemic corticotherapy with good improvement.
ABSTRACTS Abstracts e41 PP - SYSTEMIC CORTICOTHERAPY ON ORAL PEMPHIGUS VULGARIS MANAGEMENT. VICTOR YURI NICOLAU FERREIRA, TÁCIO CANDEIA LYRA, LAUDENICE DE LUCENA PEREIRA, DANYEL ELIAS DA CRUZ PEREZ, LAURA DE FÁTIMA SOUTO MAIOR, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Pemphigus vulgaris is an immuno-mediated disease characterized by multiple painful ulcerative lesions with frequent oral manifestations and treated with immunosuppressant drugs. This work aims to describe a management with systemic corticosteroids of 38 years-old male patient with multiple ulcerative and painful lesions only on oral cavity diagnosed microscopically as Pemphigus vulgaris. The lesions affected buccal mucosa bilaterally, lower and upper lip, tongue and floor of the mouth. The patient was treated with topical 0.05% clobetasol and azathioprine 50 mg/daily without clinical complete resolution. These topical formulations were followed by prednisone 80 mg/daily for two weeks and reduced progressively to 15 mg/ daily with absence of oral lesions. No systemic steroidal complications, such as hyperglycemia and hypertensive peaks were observed.
PP - PRIMARY HERPETIC GINGIVOSTOMATITIS AFFECTING AN ADULT. TA´CIO CANDEIA LYRA. VICTOR YURI NICOLAU FERREIRA, HÉLDER DOMICIANO DANTAS MARTINS, LAUDENICE DE LUCENA PEREIRA, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Primary Herpetic Gingivostomatitis (PHG) is a first clinical manifestation of an infectious disease caused by Human Simplex Virus (HSV). The clinical presentation starts after prodromal systemic manifestations. It is more common during the childhood than during the youth or adult age. The purpose of this work is to relate a case of PHG affecting a 19 years-old male, starting as an oropharyngeal infection. This patient was referred to our service complaining of painful lesion affecting oral mucosa with few days of evolution. During anamnesis, he reported an initial oropharyngeal illness, fever, prostration, cachexia and dysphagia. He was under antimicrobial therapy without resolution and with worsening of clinical manifestations. The patient also referred absence of previous herpetic infection. The extraoral examination did not show any alterations. The intraoral examination revealed multiple coalescent ulcerative lesions affecting gingival tissue, tongue, lips and hard palate. Following the history and the clinical parameters the condition was diagnosed as PHG. Supportive medications were prescribed and the patient was accompanied/ observed. One week later, the patient showed total remission of the condition.
PP - HUTCHINSON TRIAD ON CONGENITAL SYPHILIS PATIENT. TÁCIO CANDEIA LYRA, VICTOR YURI NICOLAU FERREIRA, NATHALIA PAES BARRETO DE OLIVEIRA, LAUDENICE DE LUCENA PEREIRA, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Syphilis is a chronic infection caused by Treponema pallidum and transmitted by blood, sexual fluids and vertical mode. The Hutchinson triad is the most known characteristics of fetal infection, called Congenital Syphilis: interstitial ocular keratitis, deafness, and Hutchinson teeth. This work aims to describe a case of Congenital Syphilis affecting a 16 years-old non-Caucasian
PP - PRIMARY LOCALIZED AMYLOIDOSIS ON TONGUE. VICTOR YURI NICOLAU FERREIRA, TÁCIO CANDEIA LYRA, LAUDENICE DE LUCENA PEREIRA, DANYEL ELIAS DA CRUZ PEREZ, PANMELLA PEREIRA MACIEL, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Amyloidosis is a rare disease caused by pathologic deposition of folded proteins on extracellular matrix and can be primary or secondary. This work aims to report case of primary localized amyloidosis on tongue affecting a female with 79 years-old. This patient was referred to our reference center complaining of dysphagia and painful mass on her tongue. She referred intense weight-loss during a couple of months. No alterations were observed on oral examination and the intraoral examination revealed generalized macroglossia and multiple unitary resistant nodules with yellowish surface on dorsal, lateral and ventral surfaces were clear. We considered amyloidosis as primary diagnostic hypothesis and an incisional biopsy was taken. We evaluated the feasible association with a systemic process and ordered some exams such as CBC, echocardiogram, renal ultrasound, gastrointestinal tomography, colonoscopy, radiographs of the whole body, and Bence Jones protein mensuration. All exams revealed normality and absence of signs of systemic disease. The microscopic examination revealed a proteinaceous material under positive epithelial tissue to Red Congo showing birefringence. This case was diagnosed as primary localized amyloidosis on tongue and the patient was referred to hematologist for treatment. She is currently under systemic corticotherapy with good improvement.
ABSTRACTS Abstracts e41 PP - SYSTEMIC CORTICOTHERAPY ON ORAL PEMPHIGUS VULGARIS MANAGEMENT. VICTOR YURI NICOLAU FERREIRA, TÁCIO CANDEIA LYRA, LAUDENICE DE LUCENA PEREIRA, DANYEL ELIAS DA CRUZ PEREZ, LAURA DE FÁTIMA SOUTO MAIOR, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Pemphigus vulgaris is an immuno-mediated disease characterized by multiple painful ulcerative lesions with frequent oral manifestations and treated with immunosuppressant drugs. This work aims to describe a management with systemic corticosteroids of 38 years-old male patient with multiple ulcerative and painful lesions only on oral cavity diagnosed microscopically as Pemphigus vulgaris. The lesions affected buccal mucosa bilaterally, lower and upper lip, tongue and floor of the mouth. The patient was treated with topical 0.05% clobetasol and azathioprine 50 mg/daily without clinical complete resolution. These topical formulations were followed by prednisone 80 mg/daily for two weeks and reduced progressively to 15 mg/ daily with absence of oral lesions. No systemic steroidal complications, such as hyperglycemia and hypertensive peaks were observed.
PP - PRIMARY HERPETIC GINGIVOSTOMATITIS AFFECTING AN ADULT. TA´CIO CANDEIA LYRA. VICTOR YURI NICOLAU FERREIRA, HÉLDER DOMICIANO DANTAS MARTINS, LAUDENICE DE LUCENA PEREIRA, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Primary Herpetic Gingivostomatitis (PHG) is a first clinical manifestation of an infectious disease caused by Human Simplex Virus (HSV). The clinical presentation starts after prodromal systemic manifestations. It is more common during the childhood than during the youth or adult age. The purpose of this work is to relate a case of PHG affecting a 19 years-old male, starting as an oropharyngeal infection. This patient was referred to our service complaining of painful lesion affecting oral mucosa with few days of evolution. During anamnesis, he reported an initial oropharyngeal illness, fever, prostration, cachexia and dysphagia. He was under antimicrobial therapy without resolution and with worsening of clinical manifestations. The patient also referred absence of previous herpetic infection. The extraoral examination did not show any alterations. The intraoral examination revealed multiple coalescent ulcerative lesions affecting gingival tissue, tongue, lips and hard palate. Following the history and the clinical parameters the condition was diagnosed as PHG. Supportive medications were prescribed and the patient was accompanied/ observed. One week later, the patient showed total remission of the condition.
PP - HUTCHINSON TRIAD ON CONGENITAL SYPHILIS PATIENT. TÁCIO CANDEIA LYRA, VICTOR YURI NICOLAU FERREIRA, NATHALIA PAES BARRETO DE OLIVEIRA, LAUDENICE DE LUCENA PEREIRA, PAULO ROGÉRIO FERRETI BONAN. UNIVERSIDADE FEDERAL DA PARAÍBA. Syphilis is a chronic infection caused by Treponema pallidum and transmitted by blood, sexual fluids and vertical mode. The Hutchinson triad is the most known characteristics of fetal infection, called Congenital Syphilis: interstitial ocular keratitis, deafness, and Hutchinson teeth. This work aims to describe a case of Congenital Syphilis affecting a 16 years-old non-Caucasian