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PP164-MON A NATIONAL OBSERVATIONAL SURVEY ON HEALTH CARE WORKERS’ NUTRITIONAL PRACTICES IN CANCER PATIENTS
176 Methods: A cross-sectional study in intensive care unit of surgery’s department in QSUT (University Hospital Centre, Tirana, Albania). The patients were characterized by scoring the components “undernutrition” and “severity of disease” in 4 categories (absent, mild, moderate or severe), using Nutritional Risk Screening 2002. The patient could have a score of 0 3 for each component (undernutrition and severity of disease), and any patient with a total score 3 was considered at nutritional risk. Undernutrition was evaluated by any of the 3 variables (BMI, recent weight loss, recent food intake). Results: 228 patients admitted to surgical intensive care unit (mean age was 60.0 years (18 92) were evaluated. Prevalence of patients at nutritional risk was 54.1% in admission to the ICU. Average age in patients at nutritional risk was significantly higher than in well-nourished group (mean age 65.58 years vs 54.15 years). Patient at nutritional risk had significantly (p < 0.05) higher incidence of complications (42.4% vs 28%), increased mortality (42.4% vs 30%), longer length of hospital stay (mean of 9.08 days vs 4.20 days), longer length of ventilator stay (mean of 8.229 days vs 5.21 days) compared with well-nourished group. Conclusion: Nearly 55% of patients in surgical ICU are at nutritional risk and need a nutrition plan and a plan for monitoring. New routines and staff education are needed. Identifying patient at nutritional risk on admission to hospital will help to be effective during hospitalization. Disclosure of Interest: None Declared
PP164-MON A NATIONAL OBSERVATIONAL SURVEY ON HEALTH CARE WORKERS’ NUTRITIONAL PRACTICES IN CANCER PATIENTS X. H´ ebuterne1 , J. Durand2 , S. Antoun3 , G. Calais4 , I. Krakowski5 , C. Hannequin6 , P. Senesse7 . 1 Gastroenterology and Clinical Nutrition, CHU of Nice, Nice, 2 Medical Oncology Department, Hˆ opital Cochin, Paris, 3 Oncology, Institut Gustave Roussy, Villejuif, 4 Radiotherapy, CHU of Tours, Tours, 5 Oncology, CLCC, Nancy, 6 Radiotherapy, Hˆ opital Saint-Louis, Paris, 7 Gastroenterology and Clinical Nutrition, CLCC, Montpellier, France Rationale: Malnutrition is a major concern in cancer patients, but data on nutritional practice in oncology are lacking. This survey aimed to assess nutritional screening, resources and attitudes of care givers in cancer centres. Methods: This national observational survey was conducted between 11/01/10 and 01/31/11. A selfadministered questionnaire was mailed to health care givers in all cancer centres. Results: Among the 675 responders (406 doctors (MD) [43 nutrionnists], 236 dieticians and 33 nurses), 89.7% (87.5% of MD and 93.1% of non MD) systematically or most often screened nutritional status of cancer patients. The three major variables to assess undernutrition were BMI (73.1% for total responders; 67.7% for MD/81.1% for non MD), serum albumin (72.1%;72.0%/72.8%) and body weight (66.0%;67.4%/63.8%). The two weight loss variables (5% over one month/10% over six months) were ranked among the major parameters by 79.2% of
Poster presentations responders (MD: 79.9%/non MD: 78.1%). Most responders were unaware of the recommended threshold values for risk of undernutrition: BMI < 18.5 (79.7%; MD: 87.4%/non MD: 68.0%), serum albumin <30g/L (59.0%; 59.9%/57.6%), % of weight loss over one month (39.7%; 48.8%/26.0%) and over six months (37.6%; 44.1%/27.9%). For all responders, the most commonly reported consequences of undernutrition were perioperative morbi-mortality (80.2%), anti-cancer drugs toxicities (69.1%) and altered quality of life (47.3%). Risk factors of malnutrition were tumour stage (48.2%), tumour treatment (47.6%), anorexia (47.3%). In a response of a simple clinical case, 42.0% of MD and 50.6% of non MD displayed an adequate nutritional intervention to evaluate and treat malnourished patients, respectively. Conclusion: This study showed interest and willingness for nutrition care in cancer patients in cancer centres. However, adequate assessment and treatment of undernutrition should be improved, especially in MD. Disclosure of Interest: X. H´ ebuterne Grant/Research Support from: Baxter, J. Durand Grant/Research Support from: Baxter, S. Antoun Grant/Research Support from: Baxter, G. Calais Grant/Research Support from: Baxter, I. Krakowski Grant/Research Support from: Baxter, C. Hannequin Grant/ Research Support from: Baxter, P. Senesse Grant/Research Support from: Baxter
PP165-MON THE INFLUENCE OF MENSTRUAL CYCLE ON SERUM DIAMINE OXIDASE ACTIVITY IN HEALTHY WOMEN Y. Hamada1 , Y. Shinohara1 , M. Yano2 , M. Yamamoto2 , M. Yoshio1 , K. Satake1 , A. Toda1 , M. Hirai3 , M. Usami1,4 . 1 Department of Nutrition, 2 Department of Laboratory, 3 Department of Pharmacy, Kobe University School of Medicine, 4 Division of Nutrition and Metabolism, Kobe University School of Health Science, Kobe, Japan Rationale: Since gut plays a critical role in not only absorption of nutrients but also host immune defense, it is very important to evaluate gut function of patients. Serum diamine oxidase (DAO) activity is employed as a useful marker of the integrity of intestinal mucosa. However, it has been reported the gender-related difference in serum DAO activity and women have wider range in serum DAO levels than men in health. We hypothesized that menstrual cycle may affect DAO activity. Methods: Thirty-six women, who were Japanese, were recruited among students at Kobe University School of Health Sciences and staff of Kobe University Hospital. All participants were aged from 20 to 29 and healthy. The food surveys were based on questionnaires validated by national registered dietitians in Japan. Fasting blood samples were collected from each subject in both follicular and luteal phase. Complete blood counts, biochemical parameters, and female hormones were measured. Serum DAO activity was determined by the colorimetric method of Takagi et al. Paired t tests were used for comparison between follicular and luteal phase. p < 0.05 was considered to be significant. Results: Food intakes of follicular phase were not different from those of luteal phase (34±9 kcal/kg body weight/day and 34±9 kcal/kg body weight/day, respectively). Biochemical parameters except for DAO
PP164-MON A NATIONAL OBSERVATIONAL SURVEY ON HEALTH CARE WORKERS’ NUTRITIONAL PRACTICES IN CANCER PATIENTS X. H´ ebuterne1 , J. Durand2 , S. Antoun3 , G. Calais4 , I. Krakowski5 , C. Hannequin6 , P. Senesse7 . 1 Gastroenterology and Clinical Nutrition, CHU of Nice, Nice, 2 Medical Oncology Department, Hˆ opital Cochin, Paris, 3 Oncology, Institut Gustave Roussy, Villejuif, 4 Radiotherapy, CHU of Tours, Tours, 5 Oncology, CLCC, Nancy, 6 Radiotherapy, Hˆ opital Saint-Louis, Paris, 7 Gastroenterology and Clinical Nutrition, CLCC, Montpellier, France Rationale: Malnutrition is a major concern in cancer patients, but data on nutritional practice in oncology are lacking. This survey aimed to assess nutritional screening, resources and attitudes of care givers in cancer centres. Methods: This national observational survey was conducted between 11/01/10 and 01/31/11. A selfadministered questionnaire was mailed to health care givers in all cancer centres. Results: Among the 675 responders (406 doctors (MD) [43 nutrionnists], 236 dieticians and 33 nurses), 89.7% (87.5% of MD and 93.1% of non MD) systematically or most often screened nutritional status of cancer patients. The three major variables to assess undernutrition were BMI (73.1% for total responders; 67.7% for MD/81.1% for non MD), serum albumin (72.1%;72.0%/72.8%) and body weight (66.0%;67.4%/63.8%). The two weight loss variables (5% over one month/10% over six months) were ranked among the major parameters by 79.2% of
Poster presentations responders (MD: 79.9%/non MD: 78.1%). Most responders were unaware of the recommended threshold values for risk of undernutrition: BMI < 18.5 (79.7%; MD: 87.4%/non MD: 68.0%), serum albumin <30g/L (59.0%; 59.9%/57.6%), % of weight loss over one month (39.7%; 48.8%/26.0%) and over six months (37.6%; 44.1%/27.9%). For all responders, the most commonly reported consequences of undernutrition were perioperative morbi-mortality (80.2%), anti-cancer drugs toxicities (69.1%) and altered quality of life (47.3%). Risk factors of malnutrition were tumour stage (48.2%), tumour treatment (47.6%), anorexia (47.3%). In a response of a simple clinical case, 42.0% of MD and 50.6% of non MD displayed an adequate nutritional intervention to evaluate and treat malnourished patients, respectively. Conclusion: This study showed interest and willingness for nutrition care in cancer patients in cancer centres. However, adequate assessment and treatment of undernutrition should be improved, especially in MD. Disclosure of Interest: X. H´ ebuterne Grant/Research Support from: Baxter, J. Durand Grant/Research Support from: Baxter, S. Antoun Grant/Research Support from: Baxter, G. Calais Grant/Research Support from: Baxter, I. Krakowski Grant/Research Support from: Baxter, C. Hannequin Grant/ Research Support from: Baxter, P. Senesse Grant/Research Support from: Baxter
PP165-MON THE INFLUENCE OF MENSTRUAL CYCLE ON SERUM DIAMINE OXIDASE ACTIVITY IN HEALTHY WOMEN Y. Hamada1 , Y. Shinohara1 , M. Yano2 , M. Yamamoto2 , M. Yoshio1 , K. Satake1 , A. Toda1 , M. Hirai3 , M. Usami1,4 . 1 Department of Nutrition, 2 Department of Laboratory, 3 Department of Pharmacy, Kobe University School of Medicine, 4 Division of Nutrition and Metabolism, Kobe University School of Health Science, Kobe, Japan Rationale: Since gut plays a critical role in not only absorption of nutrients but also host immune defense, it is very important to evaluate gut function of patients. Serum diamine oxidase (DAO) activity is employed as a useful marker of the integrity of intestinal mucosa. However, it has been reported the gender-related difference in serum DAO activity and women have wider range in serum DAO levels than men in health. We hypothesized that menstrual cycle may affect DAO activity. Methods: Thirty-six women, who were Japanese, were recruited among students at Kobe University School of Health Sciences and staff of Kobe University Hospital. All participants were aged from 20 to 29 and healthy. The food surveys were based on questionnaires validated by national registered dietitians in Japan. Fasting blood samples were collected from each subject in both follicular and luteal phase. Complete blood counts, biochemical parameters, and female hormones were measured. Serum DAO activity was determined by the colorimetric method of Takagi et al. Paired t tests were used for comparison between follicular and luteal phase. p < 0.05 was considered to be significant. Results: Food intakes of follicular phase were not different from those of luteal phase (34±9 kcal/kg body weight/day and 34±9 kcal/kg body weight/day, respectively). Biochemical parameters except for DAO