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PP173-SUN DIETARY PATTERNS AND PROSTATE CANCER RISK
Nutritional epidemiology I
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Methods: Seventy-two patients from our Day Hospital, 36 with AN (0M:36F, age 24.3±7 yrs, median: 23 yrs), 28 with BN (0M:28F, age 24.1±5 yrs, median: 23 yrs) and 8 with BED (5F:3M, age 26.4±5 yrs, median: 25 yrs) were assessed at baseline (T0), and then after 6 (T1) and 12 months (T2). Data (mean±SD) were statistically evaluated using Student’s t-test and ANOVA. A p < 0.05 was considered statistically significant. Results: Are shown in table. AN BN (BMI 25) BN (BMI < 25) BED
T0
T1
T2
16.5±2 (n = 36) 31.4±6 (n = 8) 20±2.5 (n = 20) 40.2±7.5 (n = 8)
18.5±1.3** (n = 36) 30.8±4.5 (n = 5) 19.7±1.7 (n = 13) 37.8±4.1** (n = 8)
18.8±1.7** (n = 12) 19.8±2 (n = 7) 38.4±4.4** (n = 7)
Conclusion: An integrated approach including psychological support and individualized dietary prescription is effective in AN and BED, but not in BN patients. BN patients are the less compliant to treatment. Further studies are needed to clarify the individual contribution of psychological support and personalized dietary prescription. Disclosure of Interest: None Declared
PP173-SUN DIETARY PATTERNS AND PROSTATE CANCER RISK E.H. Ax1 , T. Cederholm1 , W. Becker1 , B. Zethelius2 , P. Sj¨ ogren1 . 1 Public Health and Caring Sciences/Clinical Nutrition and Metabolism, 2 Public Health and Caring Science/Geriatrics, Uppsala Universitet, Uppsala, Sweden Rationale: Growing data indicate importance of dietary intake on PC risk, but studies on separate nutrients and foods are equivocal. By assessing dietary patterns these uncertainties might be diminished. We analysed the prospective risk of PC in relation to adherence to a Mediterranean-like diet and a carbohydrate-restricted diet among elderly Swedish men. Methods: This study is based on data from the Uppsala Longitudinal Study of Adult Men a population based cohort of 1138 elderly men (age 71±1). Diet data was recorded by seven days dietary records, unreliable dietary reporters where excluded and 566 men remained for analysis. Adherence to dietary patterns where assessed with established scoring systems. All individuals where grouped as low, medium or high adherent to each diet. Cases of PC where identified in the Swedish cancer register (follow-up < 16.4 years). Hazard ratios (HR) where calculated using Cox-proportional hazard regression. Remark was taken to the effect of death as a competing event. Complimentary analyses of selenium where done separately. Results: During follow-up 72 cases where recorded. There where no association between PC-risk and adherence to the Mediterranean diet. Adherence to a carbohydraterestricted diet was associated with a decreased risk of PC, HR 0.55 (p = 0.035) for medium adherent and 0.47 (p = 0.064) for high adherent individuals. Competing risks had a limited impact on risk relations whilst introducing selenium intake in multivariate analysis undermined the associations. Separate analyses indicated an inverse association of dietary selenium and PC-risk.
Conclusion: The results imply a decreased risk of PC with increased adherence to a carbohydrate-restricted diet among elderly Swedish men. Exploratory analyses indicate that a higher selenium intake might somewhat explain these associations. Disclosure of Interest: None Declared
PP174-SUN UNDERNOURISHED HOSPITAL PATIENTS: WHERE DO THEY COME FROM AND WHERE DO THEY GO AFTER ADMISSION? E. Leistra1,2 , M.A. van Bokhorst1,2 , M. Visser2,3 , H.M. Kruizenga1,2,3 . 1 Nutrition & Dietetics, VU University Medical Center, 2 Dutch Malnutrition Steering Group, 3 Health Sciences, Faculty of Earth and Life Sciences, VU University, Amsterdam, Netherlands Rationale: Nutrition support should be continued across different healthcare settings. Our aim was to determine patients’ living arrangements before admission and after hospital discharge. Methods: We analyzed longitudinal data of all admissions (24 hours) to adult departments of the VU University Medical Center (except for ICU) between 2008 2010. Nutritional status was defined at admission by SNAQ score. Living arrangement before and after admission, length of stay (LOS) and in-hospital mortality were compared between undernourished (SNAQ 3) and wellnourished (SNAQ < 3) patients. Results: Out of 35344 admitted patients 55% was screened (2008: 33%; 2009: 55%; 2010: 77%) and, of those, 13% was undernourished. Undernourished patients were older (63±16 vs. 58±18 years, p < 0.001) and more often male (52% vs. 47%, p < 0.001). They were less often admitted directly from home (63% vs. 69%, p < 0.001) and returned less often to their home (79% vs. 90%, p < 0.001). In contract, they were discharged to a nursing home more frequently (8% vs. 5%, p < 0.001) and older undernourished patients (65 years) were more often discharged to an institutional home (nursing, residential, rehabilitation or psychiatric home) than younger undernourished patients (17% vs. 6%, p < 0.001). For undernourished patients, LOS was longer (8±9 vs. 5±6 days, p < 0.001) and in-hospital mortality was much higher (7% vs. 1%, p < 0.001). Conclusion: Undernourished hospital patients are less often admitted directly from home and discharged to their own home. In addition they have longer LOS and higher in-hospital mortality. Disclosure of Interest: None Declared
PP175-SUN Outstanding abstract THE EFFECTIVENESS OF ORAL NUTRITION SUPPLEMENTATION DURING MEDICAL ROUNDS IN THE HOSPITAL: A RANDOMIZED CONTROLLED TRIAL G.V.D. Berg1 , R. Lindeboom2 , W.V.D. Zwet3 . 1 Department of Nutrition and Dietetics, Deventer Hospital, Deventer, 2 Division of clinical methods and Public Health, Academic Medical Centre, Amsterdam, 3 Department of Education and Research, Deventer Hospital, Deventer, Netherlands Rationale: Oral Nutritional Supplements (ONS) are considered standard treatment in acute malnutrition inpatients. ONS is usually provided in between meals,
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Methods: Seventy-two patients from our Day Hospital, 36 with AN (0M:36F, age 24.3±7 yrs, median: 23 yrs), 28 with BN (0M:28F, age 24.1±5 yrs, median: 23 yrs) and 8 with BED (5F:3M, age 26.4±5 yrs, median: 25 yrs) were assessed at baseline (T0), and then after 6 (T1) and 12 months (T2). Data (mean±SD) were statistically evaluated using Student’s t-test and ANOVA. A p < 0.05 was considered statistically significant. Results: Are shown in table. AN BN (BMI 25) BN (BMI < 25) BED
T0
T1
T2
16.5±2 (n = 36) 31.4±6 (n = 8) 20±2.5 (n = 20) 40.2±7.5 (n = 8)
18.5±1.3** (n = 36) 30.8±4.5 (n = 5) 19.7±1.7 (n = 13) 37.8±4.1** (n = 8)
18.8±1.7** (n = 12) 19.8±2 (n = 7) 38.4±4.4** (n = 7)
Conclusion: An integrated approach including psychological support and individualized dietary prescription is effective in AN and BED, but not in BN patients. BN patients are the less compliant to treatment. Further studies are needed to clarify the individual contribution of psychological support and personalized dietary prescription. Disclosure of Interest: None Declared
PP173-SUN DIETARY PATTERNS AND PROSTATE CANCER RISK E.H. Ax1 , T. Cederholm1 , W. Becker1 , B. Zethelius2 , P. Sj¨ ogren1 . 1 Public Health and Caring Sciences/Clinical Nutrition and Metabolism, 2 Public Health and Caring Science/Geriatrics, Uppsala Universitet, Uppsala, Sweden Rationale: Growing data indicate importance of dietary intake on PC risk, but studies on separate nutrients and foods are equivocal. By assessing dietary patterns these uncertainties might be diminished. We analysed the prospective risk of PC in relation to adherence to a Mediterranean-like diet and a carbohydrate-restricted diet among elderly Swedish men. Methods: This study is based on data from the Uppsala Longitudinal Study of Adult Men a population based cohort of 1138 elderly men (age 71±1). Diet data was recorded by seven days dietary records, unreliable dietary reporters where excluded and 566 men remained for analysis. Adherence to dietary patterns where assessed with established scoring systems. All individuals where grouped as low, medium or high adherent to each diet. Cases of PC where identified in the Swedish cancer register (follow-up < 16.4 years). Hazard ratios (HR) where calculated using Cox-proportional hazard regression. Remark was taken to the effect of death as a competing event. Complimentary analyses of selenium where done separately. Results: During follow-up 72 cases where recorded. There where no association between PC-risk and adherence to the Mediterranean diet. Adherence to a carbohydraterestricted diet was associated with a decreased risk of PC, HR 0.55 (p = 0.035) for medium adherent and 0.47 (p = 0.064) for high adherent individuals. Competing risks had a limited impact on risk relations whilst introducing selenium intake in multivariate analysis undermined the associations. Separate analyses indicated an inverse association of dietary selenium and PC-risk.
Conclusion: The results imply a decreased risk of PC with increased adherence to a carbohydrate-restricted diet among elderly Swedish men. Exploratory analyses indicate that a higher selenium intake might somewhat explain these associations. Disclosure of Interest: None Declared
PP174-SUN UNDERNOURISHED HOSPITAL PATIENTS: WHERE DO THEY COME FROM AND WHERE DO THEY GO AFTER ADMISSION? E. Leistra1,2 , M.A. van Bokhorst1,2 , M. Visser2,3 , H.M. Kruizenga1,2,3 . 1 Nutrition & Dietetics, VU University Medical Center, 2 Dutch Malnutrition Steering Group, 3 Health Sciences, Faculty of Earth and Life Sciences, VU University, Amsterdam, Netherlands Rationale: Nutrition support should be continued across different healthcare settings. Our aim was to determine patients’ living arrangements before admission and after hospital discharge. Methods: We analyzed longitudinal data of all admissions (24 hours) to adult departments of the VU University Medical Center (except for ICU) between 2008 2010. Nutritional status was defined at admission by SNAQ score. Living arrangement before and after admission, length of stay (LOS) and in-hospital mortality were compared between undernourished (SNAQ 3) and wellnourished (SNAQ < 3) patients. Results: Out of 35344 admitted patients 55% was screened (2008: 33%; 2009: 55%; 2010: 77%) and, of those, 13% was undernourished. Undernourished patients were older (63±16 vs. 58±18 years, p < 0.001) and more often male (52% vs. 47%, p < 0.001). They were less often admitted directly from home (63% vs. 69%, p < 0.001) and returned less often to their home (79% vs. 90%, p < 0.001). In contract, they were discharged to a nursing home more frequently (8% vs. 5%, p < 0.001) and older undernourished patients (65 years) were more often discharged to an institutional home (nursing, residential, rehabilitation or psychiatric home) than younger undernourished patients (17% vs. 6%, p < 0.001). For undernourished patients, LOS was longer (8±9 vs. 5±6 days, p < 0.001) and in-hospital mortality was much higher (7% vs. 1%, p < 0.001). Conclusion: Undernourished hospital patients are less often admitted directly from home and discharged to their own home. In addition they have longer LOS and higher in-hospital mortality. Disclosure of Interest: None Declared
PP175-SUN Outstanding abstract THE EFFECTIVENESS OF ORAL NUTRITION SUPPLEMENTATION DURING MEDICAL ROUNDS IN THE HOSPITAL: A RANDOMIZED CONTROLLED TRIAL G.V.D. Berg1 , R. Lindeboom2 , W.V.D. Zwet3 . 1 Department of Nutrition and Dietetics, Deventer Hospital, Deventer, 2 Division of clinical methods and Public Health, Academic Medical Centre, Amsterdam, 3 Department of Education and Research, Deventer Hospital, Deventer, Netherlands Rationale: Oral Nutritional Supplements (ONS) are considered standard treatment in acute malnutrition inpatients. ONS is usually provided in between meals,