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Pre and post resection pleural cytology in patients undergoing lung resection and mediastinal node mapping for carcinoma
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199 Tumoral volume and prognosis in limited small-cell lung carcinoma (S.C.L.C.)
BALDEYROU P., BOUAOUINA P., LE CHEVALIER T. INSTITUT GUSTAVE ROUSSY FRANCE -
N.,
ARRIAGADA
(I.G.R.)
R.,
RUFFIE
94805 VILLEJUIF
-
SUPERIORVENACAVASYNDROME (SVCSI IS A RISK FACTORFOR BRAIN NETASTASISIN SHALLCELL LUNG CANCER(SCLC). B. LEBEAU, T. URBAN, Cl. CHASTANG,for the “Petites Cellules” Group. Service de Pneumol ie, HBpital St Antoine, 184, rue du Faubourg St-Ant0o! ne. 75571 Paris Cedex 12, France.
The tumoral volumes (tumor = T, adenopathy = A, global = T t A) were studied in 90 limited SCLC ; all included in 4 successive patients were protocols of alternating radiotherapy (RT) and chemotherapy (CT) and treated at I.G.R. The volumes were drawn on frontal and lateral chest X-Ray before the first course of CT and before the second course of CT. Volumes were assimilated to spheres or cylinders. This evaluation was possible in 89/90 patients. The volume decrease was evaluated as response (2 50 %) or minimal response (
201 SURVIVAL OF PATIENTS WITH LUNG CANCER DETECTED DURING CANCER SCRFBIING IN XUAN WEI, CHINA. F.D. Hul, H.W. Zhaol, and J.L. Mumford*. IPeople's Hospital of Yunnan Province, Kunming, Environmental Protection Agency, China, *U.S. Research Triangle Park, NC, U.S.A. The Lung cancer mortality rate in Xuan Wei County, Yunnan Province is among China's highest, especially in women, and is associated with smoky coal use in This study assessed the survival unvented homes. rate of 125 Xuan Wei lung cancer patients (54 males and 71 females), who did not receive therapy after Lung cancer of these patients was being diagnosed. detected during physical examinations for cancer screening. The diagnosis was confirmed by pathology and these patients were followed. The natural l-, 2-, 3-t 4-, and 5-year survival rate of these patients was 43.2, 27.2, 16.0, 8.8, and 3.2X, respectively. One case of squamous cell carcinoma and one case of adenocarcinoma survived for 7 and 8 years, Mean survival days for squamous cell respectively. carcinoma, adenocarcinoma, anaplastic cell carcinoma, and mixed carcinoma were 723, 820, 622, and 1192 Mean survival days for all days, respectively. cancer types ranged 715-1703, 617-1263, and 336-680 There days for stages I, II, and III, respectively. was no significant difference between males and females in survival rates of all cancer types. ThiS study showed that type of cancer and stage of lung cancer affected the survival of lung cancer patients. The natural survival data can provide information on prognosis and can be used as a baseline to evaluate the effectiveness of medical intervention. NATURAL
PRE AND POST RESECTION PLEURAL CYTOLOGY IN PATIENTS UNDERGOING LUNG RESECTION AND MEDIASTINAL NODE MAPPING FOR CARCINOMA. Drs PH Cole, A Firouz-Abadi, N Johnston, A Dare, Department of Thoracic Surgery and Pathology, The Prince Charles Hospital, Brisbane, Australia. TO investigate whether pre operative fine needle aspiration biopsy (FNA) of lung carcinomas,or mediastinal node mapping contributed to the detectable spread of malignant cells in the pleural cavity,pre and post resection pleural lavages were examined for malignant cells. Patients were operable, with no evidence of pleural effusions,clinically and radiologically. Of 136 patients.90 had pre and 136 had post resection cytologies,with 88 having both. Ten of the 90 pre and 13 of the 136 post resection lavages were positive for malignant cells. In the 88 having both pre and post cytologies, 6 were both positive, 77 were both negative,with 3 being positive pre and negative post,and 2 being negative pre and positive post. Of the 6 with both positive,2 were Stage 1, 2 Stage 2 and 2 Stage 3a.4 had FNA biopsy for diagnosisthe other 2 were TlN2 and T2Nl. Of the 77 patients with both negative,39 had FNA and these were 42 Stage1 14 Stage 2,20 Stage 3a.and 1 Stage 4. In conclusion, the diagnosis by FNA does not contribute to a significant seeding of the pleural cavity of malignant cells, nor does mediastinal node mapping.
199 Tumoral volume and prognosis in limited small-cell lung carcinoma (S.C.L.C.)
BALDEYROU P., BOUAOUINA P., LE CHEVALIER T. INSTITUT GUSTAVE ROUSSY FRANCE -
N.,
ARRIAGADA
(I.G.R.)
R.,
RUFFIE
94805 VILLEJUIF
-
SUPERIORVENACAVASYNDROME (SVCSI IS A RISK FACTORFOR BRAIN NETASTASISIN SHALLCELL LUNG CANCER(SCLC). B. LEBEAU, T. URBAN, Cl. CHASTANG,for the “Petites Cellules” Group. Service de Pneumol ie, HBpital St Antoine, 184, rue du Faubourg St-Ant0o! ne. 75571 Paris Cedex 12, France.
The tumoral volumes (tumor = T, adenopathy = A, global = T t A) were studied in 90 limited SCLC ; all included in 4 successive patients were protocols of alternating radiotherapy (RT) and chemotherapy (CT) and treated at I.G.R. The volumes were drawn on frontal and lateral chest X-Ray before the first course of CT and before the second course of CT. Volumes were assimilated to spheres or cylinders. This evaluation was possible in 89/90 patients. The volume decrease was evaluated as response (2 50 %) or minimal response (
201 SURVIVAL OF PATIENTS WITH LUNG CANCER DETECTED DURING CANCER SCRFBIING IN XUAN WEI, CHINA. F.D. Hul, H.W. Zhaol, and J.L. Mumford*. IPeople's Hospital of Yunnan Province, Kunming, Environmental Protection Agency, China, *U.S. Research Triangle Park, NC, U.S.A. The Lung cancer mortality rate in Xuan Wei County, Yunnan Province is among China's highest, especially in women, and is associated with smoky coal use in This study assessed the survival unvented homes. rate of 125 Xuan Wei lung cancer patients (54 males and 71 females), who did not receive therapy after Lung cancer of these patients was being diagnosed. detected during physical examinations for cancer screening. The diagnosis was confirmed by pathology and these patients were followed. The natural l-, 2-, 3-t 4-, and 5-year survival rate of these patients was 43.2, 27.2, 16.0, 8.8, and 3.2X, respectively. One case of squamous cell carcinoma and one case of adenocarcinoma survived for 7 and 8 years, Mean survival days for squamous cell respectively. carcinoma, adenocarcinoma, anaplastic cell carcinoma, and mixed carcinoma were 723, 820, 622, and 1192 Mean survival days for all days, respectively. cancer types ranged 715-1703, 617-1263, and 336-680 There days for stages I, II, and III, respectively. was no significant difference between males and females in survival rates of all cancer types. ThiS study showed that type of cancer and stage of lung cancer affected the survival of lung cancer patients. The natural survival data can provide information on prognosis and can be used as a baseline to evaluate the effectiveness of medical intervention. NATURAL
PRE AND POST RESECTION PLEURAL CYTOLOGY IN PATIENTS UNDERGOING LUNG RESECTION AND MEDIASTINAL NODE MAPPING FOR CARCINOMA. Drs PH Cole, A Firouz-Abadi, N Johnston, A Dare, Department of Thoracic Surgery and Pathology, The Prince Charles Hospital, Brisbane, Australia. TO investigate whether pre operative fine needle aspiration biopsy (FNA) of lung carcinomas,or mediastinal node mapping contributed to the detectable spread of malignant cells in the pleural cavity,pre and post resection pleural lavages were examined for malignant cells. Patients were operable, with no evidence of pleural effusions,clinically and radiologically. Of 136 patients.90 had pre and 136 had post resection cytologies,with 88 having both. Ten of the 90 pre and 13 of the 136 post resection lavages were positive for malignant cells. In the 88 having both pre and post cytologies, 6 were both positive, 77 were both negative,with 3 being positive pre and negative post,and 2 being negative pre and positive post. Of the 6 with both positive,2 were Stage 1, 2 Stage 2 and 2 Stage 3a.4 had FNA biopsy for diagnosisthe other 2 were TlN2 and T2Nl. Of the 77 patients with both negative,39 had FNA and these were 42 Stage1 14 Stage 2,20 Stage 3a.and 1 Stage 4. In conclusion, the diagnosis by FNA does not contribute to a significant seeding of the pleural cavity of malignant cells, nor does mediastinal node mapping.