Preface to the Advances in Asthma, Allergy and Immunology, 2003 The Editors of The Journal of Allergy and Clinical Immunology recognize that our readership is faced with increasing challenges in keeping up-to-date with the literature in asthma, allergy, and immunology. We therefore felt that it would be important to publish a series of reviews highlighting pivotal papers published within the previous year and a comprehensive bibliography from the major interest sections in our field. Thus, we present the first annual Advances in Asthma, Allergy and Immunology as a supplement to the Journal. What follows is a synopsis of articles that have appeared in JACI from October 2001 through September 2002. These reports have added significantly to our knowledge and are influencing current trends in research and therapy. Selected articles appearing outside of this timeframe or in other journals have been included because they complemented or supplemented the articles that appeared in the Journal. Learning objectives for the Advances feature are: • To understand the epidemiological and scientific bases for the hygiene hypothesis of childhood asthma and allergies. • To describe the patterns of sensitization to food and
inhalant allergens in childhood that best predict the development of asthma. • To identify the revisions in the asthma guidelines that pertain to asthma management in young children. • To become familiar with the National Asthma Education and Prevention Program’s 2002 Update to their 1997 Guidelines. • To have a greater appreciation of the reality of the “one airway” concept and be able to apply it to treatment of the practitioner’s patients. • To appreciate how recent advances in anaphylaxis and hypersensitivity reactions to foods, drugs and insect venom impact current practice and may alter future diagnostic and therapeutic practices. • To review recent articles dealing with human eosinophil and basophil biology and animal models of allergic disease. • To describe new finding in the pathophysiology of allergic skin diseases and new treatment options. • To become familiar with important research progress reported in the year 2001-2002 in the field of basic and clinical immunology.