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Prevalence of Bacteria in Patients With Non-CF Bronchiectasis
March 2014, Vol 145, No. 3_MeetingAbstracts Obstructive Lung Diseases | March 2014
Prevalence of Bacteria in Patients With Non-CF Bronchiectasis Georgina Gramblicka, MD; Daniela Visentini, MD; Valeria Morandi, MD; Maria Laura Grodnitzky, MD; Gabriela Tabaj, MD; Patricia Malamud, MD; Ana Sangoy, MD; Andrea Appendino, MD; Laura Biglieri, MD; Silvia Guaycochea, MD Hospital Cetrángolo, Vicente Lopéz, Argentina
Chest. 2014;145(3_MeetingAbstracts):419A. doi:10.1378/chest.1810691
Abstract SESSION TITLE: Bronchiectasis Posters SESSION TYPE: Poster Presentations PRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PM PURPOSE: Bronchiectasis are defined as permanent, abnormal dilation of bronchi and bronchioles. Laenec in 1819, the first described them as a very common disease before the age of antibiotics. Today is a minor problem in developed countries in opposition to developing countries. The purpose of this study is to determine the prevalence of bacteria in patients with non-CF bronquiectacias. METHODS: It is a descriptive cross-sectional study to determine the prevalence of bacteria in non-CF bronchiectasis. Data comes from the Pneumology Service of the Hospital Clinic Antonio A. Cetrángolo. Vicente Lopez. Prov of Buenos Aires obtained during the period from January 1, 2011 to December 31, 2012. We studied 69 adult patients of both sexes aged 18 to 65 years with diagnosis of bronchiectasis. Were considered suitable for cultivation only those samples with direct microscopic examination of Gram staining, assessed by Murray and Washington criteria of < 10 > 25 PMN per field . Samples with normal flora of upper airway were excluded. RESULTS: Pseudomonas sp was the most common germ isolated(58%) An increased in bacterial isolatation of Stenotrophomonas maltophilia (4%)was recovered as emerging bacteria from one year to another. We noted an increased in the recovery of Staphylococcus aureus (6%) with the introduction of a selective medium. CONCLUSIONS: Severity and clinical features of bronchiectasis vary for one
patient to another depending on the length of illness and chronic infection. The progression of bronchiectasis depends on the persistence of bacterial infection. It is importan to reduce the load of bateria in this population. Antibiotics should be directed to specific germs, becoming sputum culture the best way for the identification and antibiotic sensitivity to guide treatment. CLINICAL IMPLICATIONS: Optimizing antibiotic treatment of bronchiectasis NON -CF according to specific bacteria. DISCLOSURE: The following authors have nothing to disclose: Georgina Gramblicka, Daniela Visentini, Valeria Morandi, Maria Laura Grodnitzky, Gabriela Tabaj, Patricia Malamud, Ana Sangoy, Andrea Appendino, Laura Biglieri, Silvia Guaycochea No Product/Research Disclosure Information
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Prevalence of Bacteria in Patients With Non-CF Bronchiectasis Georgina Gramblicka, MD; Daniela Visentini, MD; Valeria Morandi, MD; Maria Laura Grodnitzky, MD; Gabriela Tabaj, MD; Patricia Malamud, MD; Ana Sangoy, MD; Andrea Appendino, MD; Laura Biglieri, MD; Silvia Guaycochea, MD Hospital Cetrángolo, Vicente Lopéz, Argentina
Chest. 2014;145(3_MeetingAbstracts):419A. doi:10.1378/chest.1810691
Abstract SESSION TITLE: Bronchiectasis Posters SESSION TYPE: Poster Presentations PRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PM PURPOSE: Bronchiectasis are defined as permanent, abnormal dilation of bronchi and bronchioles. Laenec in 1819, the first described them as a very common disease before the age of antibiotics. Today is a minor problem in developed countries in opposition to developing countries. The purpose of this study is to determine the prevalence of bacteria in patients with non-CF bronquiectacias. METHODS: It is a descriptive cross-sectional study to determine the prevalence of bacteria in non-CF bronchiectasis. Data comes from the Pneumology Service of the Hospital Clinic Antonio A. Cetrángolo. Vicente Lopez. Prov of Buenos Aires obtained during the period from January 1, 2011 to December 31, 2012. We studied 69 adult patients of both sexes aged 18 to 65 years with diagnosis of bronchiectasis. Were considered suitable for cultivation only those samples with direct microscopic examination of Gram staining, assessed by Murray and Washington criteria of < 10 > 25 PMN per field . Samples with normal flora of upper airway were excluded. RESULTS: Pseudomonas sp was the most common germ isolated(58%) An increased in bacterial isolatation of Stenotrophomonas maltophilia (4%)was recovered as emerging bacteria from one year to another. We noted an increased in the recovery of Staphylococcus aureus (6%) with the introduction of a selective medium. CONCLUSIONS: Severity and clinical features of bronchiectasis vary for one
patient to another depending on the length of illness and chronic infection. The progression of bronchiectasis depends on the persistence of bacterial infection. It is importan to reduce the load of bateria in this population. Antibiotics should be directed to specific germs, becoming sputum culture the best way for the identification and antibiotic sensitivity to guide treatment. CLINICAL IMPLICATIONS: Optimizing antibiotic treatment of bronchiectasis NON -CF according to specific bacteria. DISCLOSURE: The following authors have nothing to disclose: Georgina Gramblicka, Daniela Visentini, Valeria Morandi, Maria Laura Grodnitzky, Gabriela Tabaj, Patricia Malamud, Ana Sangoy, Andrea Appendino, Laura Biglieri, Silvia Guaycochea No Product/Research Disclosure Information
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