Prevalence study of cognitive impairment no dementia (CIND) and dementia in tremembé, brazil

Prevalence study of cognitive impairment no dementia (CIND) and dementia in tremembé, brazil

MMSE 6 Mini-Mental State Examination: MoCA6 Montreal Cognitive Assessment Male P value (n ¼ 189) 64.2262 78 63 9762.74 0.359 75.0462.81 74836282 0.5...

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MMSE 6 Mini-Mental State Examination: MoCA6 Montreal Cognitive Assessment

Male P value (n ¼ 189)

64.2262 78 63 9762.74 0.359 75.0462.81 74836282 0.505 832562 79 83.0862 51 0.638 91226148 105.663 54 9 3963.04 0.001 9 1364.76 56664 89 <0.001 73564 54 2 8963 91 <0.001 9 5665 77 27.9163 33 27.5162.88 0.203 26.0264 95 23 5065 56 <0.001 225467. 18 8067.03 <0.001 21117.41 25.2064.37 24 2464 48 <0.001 22.0066.21 18.5866.90 <0.001 18.0267.72 135766.99 <0.001 14.7866 89

Male P value (n ¼ 9) Female (n ¼ 221) Male P value (n ¼ 140)

70-79 years 60-69 years

Female n ¼ 586 (583) Male n ¼ 419 (41.7%)

Age 72.7268.46 72.2268.43 730 68.46 0.117 Education 7.6464.85 9.4064.40 6.4064.77 <0.001 MMSE 24.7066.12 260665.48 23.7366.37 <0.001 MoCA 20.6667.28 22.4666.54 19367.51 <0.001

Tao Wang1,2, Shifu Xiao1, Cece Yang1,2, Shuhui Dong1,2, Yan Cheng1,2, Xia Li1,2, Jinghua Wang1, Minjie Zhu1, Fuzhong Yang1, Guanjun Li1, Ning Su1, Yuanyuan Liu1, Kewei Chen3, 1Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China; 2 Alzheimer’s Disease and Related Disorders Center, Shanghai Jiao Tong

Table 1 Baseline demographic characteristics of all subjects

PREVALENCE AND INCIDENCE OF DEPRESSION DISORDER AND COGNITIVE IMPAIRMENT IN THE ELDERLY IN SHANGHAI, CHINA

P value

Background: Dementia is one of the major health issues due to the

P4-141

Female (n ¼ 130) Male (n¼ 84)

80-89 years

Karolina G. Cesar1,2, Sonia M.D. Brucki1, Leonel T. Takada1, Luiz Fernando C. Nascimento2, Camila M.S. Gomes2, Milena C.S. Almeida2, Maira O. Oliveira1, Fabio H.G. Porto1, Mirna L.H. Senaha1, Valeria S. Bahia1, Thais Bento Lima Silva1, Jessica N. Ianof1, Mario A. Cecchini1, Luciana Cassimiro1, Marcia R. Gonc¸alves1, Jerusa Smid1, Claudia S. Porto1, Maria Teresa Carthery-Goulart3, M^onica Sanches Yassuda1, Leticia L. Mansur1, Ricardo Nitrini, Sr,1, 1University of S~ao Paulo, S~ao Paulo, Brazil; 2University of Taubate, Taubate, Brazil; 3Universidade Federal do ABC, S~ ao Bernardo do Campo, Brazil. Contact e-mail: [email protected]

rapidly growing elderly population, with an estimated prevalence of 8.5% in Latin American studies. The aim of this study was to ascertain the prevalence of cognitive impairment no dementia (CIND) and dementia in a community-dwelling elderly in Brazil. Methods: This was a single phase epidemiological study with the elderly (aged 60 years) living in the municipality of Tremembe, Brazil. Twenty percent of the households with elderly were randomly selected from urban and rural areas, in order to obtain a homogeneous representation of all socioeconomic and cultural levels. In addition to clinical and neurological evaluations, questionnaires were applied to informants to assess functional activities (Informant Questionnaire on Cognitive Decline in the Elderly [IQCODE] and Pfeffer Functional Activities Questionnaire); and neuropsychological tests were administered to participants (Brief Cognitive Screening Battery, Mini-Mental State Examination, verbal fluency test and clock drawing test) along with psychiatric rating scales. Results: We assessed 630 individuals (mean age, 71.3 years; mean years of education, 4.9) and found prevalence rates of 17.5% (95% CI: 14.6 - 20.6) for dementia and 19.5% (95% CI: 16.6 - 22.8) for CIND. These prevalences were influenced by age (p< 0.001) and by educational level (p< 0.001). There was no significant gender difference among diagnostic groups (p¼ 0.166). The prevalence of dementia was higher in relatively younger individuals (<70 years old) when compared to other studies. Diagnosis of dementia was significantly associated with low socioeconomic status, stroke, previous psychiatric disorder, alcoholism, and epilepsy, while diagnosis of CIND was only associated with stroke. Conclusions: The prevalence of dementia in this study was higher than in other studies, particularly among younger elderly.

Female (n ¼ 16)

90+ years

PREVALENCE STUDY OF COGNITIVE IMPAIRMENT NO DEMENTIA (CIND) AND  BRAZIL DEMENTIA IN TREMEMBE,

Female (n ¼ 209)

P4-140

P value

within the range of that reported in other international studies (3.2 – 24.3%). The finding that the amnestic type is more common than the non-amnestic type is also in agreement with most literature. Data collection is ongoing and the final results will be presented at AAIC in July 2015.

920662 49 0 367 2 8664 17 0.004 152569 21 <0.001 113868 53 <0.001

Poster Presentations: P4

Parameter All

P832