Principles of research in biology and medicine

Principles of research in biology and medicine

720 BOOK J. Chron. Dis. December, 1958 REVIEWS however, the book does not rise sufficiently above this level to be considered a delinitive analysi...

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720

BOOK

J. Chron. Dis. December, 1958

REVIEWS

however, the book does not rise sufficiently above this level to be considered a delinitive analysis of our present position with regard to regional enteritis. When one considers just how confusing that position is, perhaps it is just as well that we have to wait for a few more years until we have Meanwhile, there is a wealth of information on enteritis in Dr. Crohn’s book, such an analysis. and it can be recommended to the general internist and surgeon as well as to medical students for an over-all description of the disease as seen in the largest group of cases followed by one man. Albert

I. Mendeloff

By Dwight J. Ingle, B.S., PRINCIPLES OF RESEARCH IN BIOLOGY AND MEDICINE. Price $4.75. Pp. 123, indexed. MS., Ph.D. Philadelphia, 1958, J. B. Lippincott Company. Dr. Ingle covers This is an unusual and readable book by an extraordinary research scientist. An outstanding chapter everything from causality to the administration of research organizations. is the one which is entitled “Heteropoietic Factors” and covers the ground discussed so well by The bibliography is limited the author in an old volume of Recent Progress in Hormone Rexarch. but choice. I am sure that Dr. Ingle has purposely kept the book short, but this has of necessity led to The work would probably serve best as a test for a course incomplete coverage of some topics. on research, if one could guarantee that Ingle (or a reasonably facsimilar Ingloid) would teach the course. Recommended for new, unspoiled investigators and jaded old ones. Louis Lasagna

BIOPHYSICAL PRINCIPLES OF ELECTROCARDIOGRAPHY. By Robert H. Bayley, M.D. New York, 1958, Paul B. Hoeber, Inc. Pp. 237, 141 ills., indexed. Price $8.00. For the clinical electrocardiographer, this book interprets intelligibly and consistently the normal and pathologic ECG in terms of the simple physical model of Wilson and Bayley. Infarction and injury to specific parts of the myocardium are related rationally to the various porClinical significance is tions of the QRS, S-T, and T regions. The latter are especially clear. stressed throughout. The title, biophysics, however, is somewhat ambitioits. The research of the last 15 years on quantitative effects of body-contour, lead-theory, inhomogeneity, and pattern of depolarization is hardly mentioned. The Wilson model accounts for these effects in such a cumbersome way that it has been superseded by the dipole-multipole approach. Consequently this volume would be of little help to those who wish to understand current biophysical research in electrocardiography. Samuel A. Talbot

CHRONIC BRONCHITIS, EMPHYSEMA AND COR PULMON.\LE. By C. H. StuartHarris, M.D., F.R.C.P., and T. Hanley, M.D., M.R.C.P. Bristol. 1957, John \\:right & Baltimore, exclusive U.S. agents. Pp. 24.5, Sons, Ltd. Williams & \filkins Company, indexed. Price $8.50. This is an excellent monograph dealing with a subject that is perplexing to students of emphysema. It gives a well-organized account of a combination of conditions that are so common in England. The term “chronic bronchitis” is practically synonymous with emphysema. The authors state that “frequent reference has been made to emphysema as a complication and almost This is not, by any means, the experience in this counconstant associate of chronic bronchitis.” The data are well presented in a very However, this is a very worthwhile presentation. try. The charts are not complicated and are easily followed while reading the text. readable form. The illustrations are of a better than average quality. The chapters devoted to car pulmonale give a concise view of the clinical picture and the pathologic physiology.