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Probit Analysis. 2nd ed. By D. J. Finney. Cambridge University Press, New York, 1952. 22.5 × 14 cm. xiv + 318 pp
Book Notices Methods in Medical Krseurah. Vol. 6. A. C. CORCORAN, Editor-iti-Chief. The Year Book Publishers, Inc., 1952. xiii 394 pp. 14.5 x 22.5 cm. Illustrated. Price $7.50. While this book is primarily of medical application, it also includes much of pharmaceutical interest. Many of the methods described can be adapted to the needs of research workers not directly conccrncd with problems related to basic medical research. The book is divided into three sections. The first section, dealing with methods for separation of complex mixtures and higher molecular weight substances, is of a more general nature. In this section, applications involving countcrcurrcnt distribution, paper chromatography, electrophoresis, and ultracentrifugation are discussed. In scction 11, methods of renal study are covered by ten coiltributions, several of which are divided into two or more parts. This section includes much of pharmacological and biochemical interest. Section 111, devoted to immunocheniical methods for determining homogeneity of proteins and polysaccharides, includes immunological methods of a wide scope and importance based on information not othcrwise readily accessible.
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Applied Physiology. By SAMSON WRIGHT. Oxford University Press, New York, 1952. xvi 1190 pp. 22.5 x 15 cm. Illustrated. Price $9.00. This compreheusive textbook on physiology has now been revised eight times since the first edition was published in 1926. This record indicates, to some extent, the popularity of the work. The new ninth edition of Applied Physiology has undergone a more thorough revision than any heretofore. The subject matter has been rearranged and more than half the text has been completely rewritten to reflect rccent advances in physiology. The number of illustrations has been increased by the inclusion of 200 new figures chosen mainly from recent papers. Throughout the book the clinical aspects of physiology are stressed, but despite this emphasis it should serve as a useful reference book for students whose interests are more inclined toward a gcncral treatise on physiology and those who expect to become physicians. The book is documented with references to review articles and other papers pertinent to each subject discussed. The volume is provided with au unusually complete index, and th.e printing and binding are of good quality.
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‘The text has been prepared in an dart to standardize the methods of probit analysis and to make its use available to the biologist without statistical training. The main outliiie of the fundamental mathematical theory is indicated. The theory of the analysis of quanta1 rcsponse data is discussed. The text material is covered under the following headings: Introductory (Definitions and Terms), Quanta1 Responses and the Dosage-Response Curve, Median ERective Dose, Maximum Likelihood Solution, Comparison of Effectiveness, Adjustments for riatural Mortality, Factorial Experiments, Toxic Action of Mixtures of Poisions, Graded Responses, Miscellaneous Problems, and Rcccnt Developmcnts. The author’s method of illustration by cxample is developed with the usc of 34 examples covering as many differeut problems. The large number of examples is indicative of the rapid growth in this field since the appearance of R. A. Fischer’s Statistical Methods f o r Research Workers in 1925. The explanations in Dr. Finney’s book are clcar, but one feels that unless the worker is constantly in touch with this subject, the advice that one should coilsult a statistician in these studies is more pertienent now than when Fisher offered it in 1925. This book can bc helpful t o the novice and to the expert in the bioassay field, and it should be available in rcfcrence libraries.
Experimental iVucleonics. By ERNSTBLEULERand GEORGE J. GOLDSMITH.Rinehart arid Company, 393 pp. 16 x 23.5 Inc., New York, 1952. xv cm. Price$;6.50. This book has been designed to serve as a basis for the training of people planning to perform tracer research, as well as for students of nuclear physics. It is not an elementary textbook, and in order to read it with understanding, a background of the fundamentals of nuclear physics and of chemistry is necessary. The book is conveniently divided into four major sections. In the first division is presented information conccrning the laboratory itself, the equipment, procedures in health protection, and other essential background material. Under the division hcadcd “Gcneral Techniques,” operations essential to anyone working in the field, regardless of the specialty involved, are described. This section includes many counting experiments involving cquipmcnt that will ordinarily bc encountered in experimental work on nuclear radiations. Throughout the section the role of chemistry is cmphasizcd. Probil Analysis. 2nd cd. By D. J. FINNEY. In the other two sections chemical techniques and Cambridge University Press, New York, 1952. physical techniques, including numerous experi318 pp. 22.5 x 14 a n . xiv ments, are adequately treated. The book is documented with references for supAs indicated by the sub-title, “A Statistical Treatplementary reading and is provided with an apment of thc Sigmoid Response Curvc,” this book deals with the application of statistics t o biological pendix containing useful physical constants and assays. These assays are used to determine the with author and subject indexes. This volume effect and efficiency of insecticides, fungicides, drugs, should be useful to any worker in the field of experimental nucleonics. vitamins, and other substances.
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627
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Applied Physiology. By SAMSON WRIGHT. Oxford University Press, New York, 1952. xvi 1190 pp. 22.5 x 15 cm. Illustrated. Price $9.00. This compreheusive textbook on physiology has now been revised eight times since the first edition was published in 1926. This record indicates, to some extent, the popularity of the work. The new ninth edition of Applied Physiology has undergone a more thorough revision than any heretofore. The subject matter has been rearranged and more than half the text has been completely rewritten to reflect rccent advances in physiology. The number of illustrations has been increased by the inclusion of 200 new figures chosen mainly from recent papers. Throughout the book the clinical aspects of physiology are stressed, but despite this emphasis it should serve as a useful reference book for students whose interests are more inclined toward a gcncral treatise on physiology and those who expect to become physicians. The book is documented with references to review articles and other papers pertinent to each subject discussed. The volume is provided with au unusually complete index, and th.e printing and binding are of good quality.
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‘The text has been prepared in an dart to standardize the methods of probit analysis and to make its use available to the biologist without statistical training. The main outliiie of the fundamental mathematical theory is indicated. The theory of the analysis of quanta1 rcsponse data is discussed. The text material is covered under the following headings: Introductory (Definitions and Terms), Quanta1 Responses and the Dosage-Response Curve, Median ERective Dose, Maximum Likelihood Solution, Comparison of Effectiveness, Adjustments for riatural Mortality, Factorial Experiments, Toxic Action of Mixtures of Poisions, Graded Responses, Miscellaneous Problems, and Rcccnt Developmcnts. The author’s method of illustration by cxample is developed with the usc of 34 examples covering as many differeut problems. The large number of examples is indicative of the rapid growth in this field since the appearance of R. A. Fischer’s Statistical Methods f o r Research Workers in 1925. The explanations in Dr. Finney’s book are clcar, but one feels that unless the worker is constantly in touch with this subject, the advice that one should coilsult a statistician in these studies is more pertienent now than when Fisher offered it in 1925. This book can bc helpful t o the novice and to the expert in the bioassay field, and it should be available in rcfcrence libraries.
Experimental iVucleonics. By ERNSTBLEULERand GEORGE J. GOLDSMITH.Rinehart arid Company, 393 pp. 16 x 23.5 Inc., New York, 1952. xv cm. Price$;6.50. This book has been designed to serve as a basis for the training of people planning to perform tracer research, as well as for students of nuclear physics. It is not an elementary textbook, and in order to read it with understanding, a background of the fundamentals of nuclear physics and of chemistry is necessary. The book is conveniently divided into four major sections. In the first division is presented information conccrning the laboratory itself, the equipment, procedures in health protection, and other essential background material. Under the division hcadcd “Gcneral Techniques,” operations essential to anyone working in the field, regardless of the specialty involved, are described. This section includes many counting experiments involving cquipmcnt that will ordinarily bc encountered in experimental work on nuclear radiations. Throughout the section the role of chemistry is cmphasizcd. Probil Analysis. 2nd cd. By D. J. FINNEY. In the other two sections chemical techniques and Cambridge University Press, New York, 1952. physical techniques, including numerous experi318 pp. 22.5 x 14 a n . xiv ments, are adequately treated. The book is documented with references for supAs indicated by the sub-title, “A Statistical Treatplementary reading and is provided with an apment of thc Sigmoid Response Curvc,” this book deals with the application of statistics t o biological pendix containing useful physical constants and assays. These assays are used to determine the with author and subject indexes. This volume effect and efficiency of insecticides, fungicides, drugs, should be useful to any worker in the field of experimental nucleonics. vitamins, and other substances.
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627
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