Prostate Cancer

Prostate Cancer

E1etabolic acidosis. /.'l_tnother a tubular diso:rder "'"'""'"rn,,; in retention of acid JVith cblo:ride. 5) The use of ,mcvc,µ,"u,e should be monitor...

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E1etabolic acidosis. /.'l_tnother a tubular diso:rder "'"'""'"rn,,; in retention of acid JVith cblo:ride. 5) The use of ,mcvc,µ,"u,e should be monitored especially if a patient is on a low protein diet that will decrease vv,A,"-''"u of nonvolatile acids. The con1bination may restrict the availability of fer titratable acid and this could further limit net acid excretion. In summary, aside from its '"''m,M•m•~,,,h, chronic renal failure differs from acute renal failure in several respects. The chronic form is gradual in development and often progressive. mechanisms, which maintain water and solute homeostasis until 70 to 80 per cent of the nephrons are ntoQn·,rn·<>n provide the to management before onset of uremia, vvhen dialysis therapy is mandated. 6 figures, 5 tables, 6 references

Abstractor's comment. The depth and scope of this article make a suitably comprehensive abstract near Therefore, the interested reader is urged to read the article in its entirety. E.D, W. Isosexual Precocious Puberty 'With Luteinized F'ollicular Cyst MuECRLER, A. J,

D,

CARY

AND

M. Uni·

filtration rat,o;. The infusion ofindometh~c,c;,o;.~·r.'c.'::;.·,.,;:,y :reduced urine fiow :rate~ rr,,w,,.<-,'"" filtration rate and total renal blood flow responses in animals with relea.se of ureteral occlusion after 24 hours but did not affect these results in animals after unilateral h,-·,0 ,0 1-,wnu or persisting ureteral occlusion. "''"~'""'~U=•·.r inclomethacin abolished recovery of filtration rate and total renal blood flow in the kidney after the release of ureteral occlusion. These data might suggest that this adaptive response could be prostaglandin mediated and do suggest that the contralateral in studies of unilateral ureteral occlusion cannot be assumed to have nor:mal function and should not be used as the control organ in studies of obstructive uropa .. G.W.K. l 3 tables, 20 references

E.

STRAUB AND

J.

SPRANGER,

Children's u,,_,.,,.,,, ..,._,,,., Univer-

}!lainz, Kidney Int., 20: 695-699 (Dec,) 1981 The authors present the clinical features of 14 the prune The tuous

n!>nc,nr·Q

with tor-

and N. Y, State J. Med., 82: 1353-1356

1982

A 7-year-old girl presented with precocious puberty. She was found to have a right ovary containing a 4 cm. and 4, 2 to 3 mn-1. cysts. After the cysts were removed the had no further episodes of vaginal uHee•.1u1,e:. after 18 rnonths breast and axillary hair The authors suggest that sexual ,m"'"''"''"'',." associated with ovarian follicle cyst is owing to central activation of the axis. suggest that it may be µucncuouu.u" and pituitary ovarian foHide cysts. 2 figures, 2 tables, 19 references

megaureter in other ,.,ac,~"'"'"· The 12 mal urethra associated with a small or absent prostate. Urethral obstruction was demonstrated in only 4 patients, all Six demonstrated classical prune m,,w,mfi while in 7 others \rn.cn,wu;: 2 of the abdominal musculature v1as confirrned. The authors relate their observations to the and C011dude that the r.unn,l"r.AQa

cf

01·,1naoa·.r

consequences of intrauterine obstructive

G.WJ( 2 tables, 48 references

BOOK REVmw

MISCELLANE;OUS Inhibition l[n_dorn-ethadn of·'""'"'""-'''''"' ·~""A"'''-~·D in the Contralateral ~-····"·~~·., AfteI" Release of Unila1.;ce1·al Ure~ te:n,-1 Occ1m,ion M. J.

K. UPADHYAYA Pediatrics and 1:'lUfi:ot,oflV Yale "u.u.:,,wc:. New Haven, Connecticut

Edited Gur>ther R Jacobi and Rudolf Hohenfellner. Volume 3 cf International ,J~C"Q'nc.,,h In Edited John A_ Libertino. Baltimore: The Willian:,s & Wilkins 1982, 485 pages,

SIEGEL,

School

Int., 20: 691-694 (Dec.) 1981

The authors attempted to delineate the changes that occur in the contralateral kidney after release of unilateral ureteral obstruction in rats and to compare these changes to the changes that occur after the loss of renal mass or function and, additionally, to determine if these changes could be altered by the infusion of indomethacin. Urine flow rates were increased in rats undergoing either unilateral nephrectomy or unilateral occlusion. There was a small increase in glomerular filtration rate in animals with unilateral nephrectomy and persistent ureteral occlusion but a markedly increased glomerular filtra-

The authors and editors have The of cancer is research as well as clinical issues in a and fair manner. For -,"-,,,,-,,,- there are 22 authors and their associates, representing 7 European countries and Japan. Each chapter generally is supplemented an editorial comment that is fair and lends a good perspective to the topic. Anyone, I believe, would find it hard today to improve on this contribution. The new chapters on Stereology, Histophotometric Diagnosis and Nucleic Acid Determinations for Monitoring Therapy are the most up-to-date one can find anywhere. In summary it is a good book on a difficult topic that any urologist at any stage of development, or oncologist for that manner, ought to read and enjoy. G.P.111.